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VTAAASSPAALDSDPFRQRLLEGLVASIGERGYHATTVADIVRHARTSKRTFYDRFESKEQCFLDLLRAD NERLAKRIRAAVDPEADWQAQIRQAVEAYLSHIESRLAVTLSWIREFPSLGPISYPVQRHGMNLLTSLLV ELSASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIVEPAVDASIALVGPRH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4775 | - | - | 100% (201) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_0323 | - | 2e-07 | 37.50% (80) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_4864 | - | 4e-07 | 30.06% (173) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0140c | - | 3e-83 | 78.00% (200) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1103 | - | 7e-59 | 61.33% (181) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0135c | - | 3e-83 | 78.00% (200) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 1e-06 | 28.87% (97) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 3e-07 | 34.38% (96) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 1e-110 | 99.50% (201) | transcriptional regulatory protein |
| M. avium 104 | MAV_5161 | - | 5e-75 | 68.66% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6480 | - | 4e-64 | 65.22% (184) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0083 | - | 5e-64 | 63.78% (196) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5713 | - | 3e-53 | 54.87% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1103|M.gilvum_PYR-GCK ------------------MNDRLLDGLASSIVERGYRETTVADIVRHAKT
Mvan_5713|M.vanbaalenii_PYR-1 MRTTPLAAGPHP-----SVADRLLDGLASAITERGYRDSTVADVVRYART
MUL_4775|M.ulcerans_Agy99 MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATTVADIVRHART
MMAR_0345|M.marinum_M MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATTVADIVRHART
Mb0140c|M.bovis_AF2122/97 MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATTVSDIVRHART
Rv0135c|M.tuberculosis_H37Rv MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATTVSDIVRHART
MAV_5161|M.avium_104 MTATDGEPDLGE---IDPFRLRLLDGLATSIGERGYRASTVADVVRCART
TH_0083|M.thermoresistible__bu MTTAVQPADVGAG--DDAFRGRLLSGLAASIAERGYRETTVADIVRHART
MSMEG_6480|M.smegmatis_MC2_155 MTTALTGTATAGGSGGDAFRSRLLDGLSTAIDDKGYRDSTVADIVRHART
MAB_1379c|M.abscessus_ATCC_199 MPEQLSRFERRK----QETRREILGAALACFAERGYHATGIADIVRRVGI
MLBr_02568|M.leprae_Br4923 MAGGAKRIPRAVR------EQQMLDAAVQMFSVNGYHKTSMDAIAAEAQI
.:* . : .**: : : :. .
Mflv_1103|M.gilvum_PYR-GCK SKRAFYEQFASK----EQCLIELLRNNNTDLIAHINAAVDPESDWREQIG
Mvan_5713|M.vanbaalenii_PYR-1 SKRTFYEQFASK----EECLIEMLRRNHSDLIAGIGAAVEPEADWRLQID
MUL_4775|M.ulcerans_Agy99 SKRTFYDRFESK----EQCFLDLLRADNERLAKRIRAAVDPEADWQAQIR
MMAR_0345|M.marinum_M SKRTFYDRFESK----EQCFLDLLRADNERLAKRIRAAVDPEADWQAQIR
Mb0140c|M.bovis_AF2122/97 SKRTFYDRFTSK----EQCFLELLLADNETLGNSIRAAVDPNADWHDQIR
Rv0135c|M.tuberculosis_H37Rv SKRTFYDRFTSK----EQCFLELLLADNETLGNSIRAAVDPNADWHDQIR
MAV_5161|M.avium_104 SKRTFYDHFAGK----EECFLELLAVDIEKLGAKIAASVDPEADWHVQIR
TH_0083|M.thermoresistible__bu SKRTFYDQFGSK----EECFQELLWANNIDMIGAIRAAVDPEADWSEQIR
MSMEG_6480|M.smegmatis_MC2_155 SKRTFYDQFASK----EACFIELLRANNAALVEHIRSAVSPEAEWQDQID
MAB_1379c|M.abscessus_ATCC_199 AQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLAEYRDQAE
MLBr_02568|M.leprae_Br4923 SKPMLYLYYGSK----EDLFGACLNREMSRFIAMVRADIDFTQSPKDLLR
:: :* : .* * : : : : .
Mflv_1103|M.gilvum_PYR-GCK QAVDAYIGHISARPAITLCWIREAPALGAVARP---LHRQVMRDLTEMLT
Mvan_5713|M.vanbaalenii_PYR-1 KAVGAYIDHISARPAITLCWIREAPGLGAAARP---LHRLVMGDLTDLLV
MUL_4775|M.ulcerans_Agy99 QAVEAYLSHIESRLAVTLSWIREFPSLGPISYP---VQRHGMNLLTSLLV
MMAR_0345|M.marinum_M QAVEAYVSHIESRLAVTLSWIREFPSLGPISYP---VQRHGMNLLTSLLV
Mb0140c|M.bovis_AF2122/97 QAVEAYVTHIESRPAVTLSWIREFPSLGAAAYP---VQRRGMEQLTSLLI
Rv0135c|M.tuberculosis_H37Rv QAVEAYVTHIESRPAVTLSWIREFPSLGAAAYP---VQRRGMEQLTSLLI
MAV_5161|M.avium_104 QAVEAYVGYIEARPAITLSWIRELPSLGAAARP---VQRRGLQLLTSLLI
TH_0083|M.thermoresistible__bu QAVVAYVDHIESRPAITLAWIRELPAIGASVRP---IQRAMMHELTELLI
MSMEG_6480|M.smegmatis_MC2_155 QAVGAYVEHIESAPSITLSWIRELPALGPAARP---LQRDAMGALTDLLI
MAB_1379c|M.abscessus_ATCC_199 HISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAAIQATYL
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANRASWIVMYIQAMSLPAFAQT----VREARDQITELVA
: : :.: : .: :
Mflv_1103|M.gilvum_PYR-GCK ALTGSSGFRRAGLQP--IEPAIALILLG----GLRELT---ALFVEDGRD
Mvan_5713|M.vanbaalenii_PYR-1 SLTGNPGFRRAGLDP--ITAPVALILVG----GLRELT---ALFVEDERD
MUL_4775|M.ulcerans_Agy99 ELSASPGFRRAGLPA--VPGALAVILLG----GLRELT---ALTVEDGRD
MMAR_0345|M.marinum_M ELSASPGFRRAGLPA--VPGALAVILLG----GLRELT---ALTVEDGRD
Mb0140c|M.bovis_AF2122/97 ELSASPGFRRANLPP--LNVPLAVILLG----GLRELT---ALTVEDGQP
Rv0135c|M.tuberculosis_H37Rv ELSASPGFRRANLPP--LNVPLAVILLG----GLRELT---ALTVEDGQP
MAV_5161|M.avium_104 DLSASPGFRRAQLPP--LTAPLAVILLG----GLRELT---ALAVEDGKP
TH_0083|M.thermoresistible__bu ELSRSPGFARAQMPP--LTRQLAVFLLG----GLRELT---ALFVEDGRD
MSMEG_6480|M.smegmatis_MC2_155 DLSDSPGFRRAGLNG--LSRQMAIILLG----GLRELT---ALIVEDGHD
MAB_1379c|M.abscessus_ATCC_199 QHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSP--AAFEQLAHA
MLBr_02568|M.leprae_Br4923 GLMR-VGTRSSRPDH--EYEIMAGALVGAGEAMATRLTTGDIAVDEAAEL
* : : *:. : : .
Mflv_1103|M.gilvum_PYR-GCK MRGIAGPATAAAVALLGPH-------
Mvan_5713|M.vanbaalenii_PYR-1 VHGIAAPAVAAATALVSAG-------
MUL_4775|M.ulcerans_Agy99 IREIVEPAVDASIALVGPRH------
MMAR_0345|M.marinum_M IREIVEPAVDASIALVGPRH------
Mb0140c|M.bovis_AF2122/97 IRNIVEPAVDASIALLGPRS------
Rv0135c|M.tuberculosis_H37Rv IRNIVEPAVDASIALLGPRS------
MAV_5161|M.avium_104 VRGIVEPAVDASVALLGPRH------
TH_0083|M.thermoresistible__bu VRGLIAPAVSASKALLSAGASE----
MSMEG_6480|M.smegmatis_MC2_155 IREIYEPAVAASRAILTASSAEHQAR
MAB_1379c|M.abscessus_ATCC_199 VREILYYGLASDHHPQIAD-------
MLBr_02568|M.leprae_Br4923 MINLFWHGLKGAPADRDFGPSIVAG-
: : . .