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RKIPAQISERLPAAAELFAERGLNDTKIEDVAATTGIAKATLYYYFAGKEEILAFLLEDVLQHVADEVTA IVEADGTAAQRLHTVINAQLRVMAQRPAVCRALIGELGRAARMPAIADMITTAYFEPVETLLRAGAADGS LVALDKPRAAAIALFGAVTISALTYLITDDALNEELIARTIHDVAFIGLRPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4832 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0684 | - | 6e-11 | 33.33% (117) | putative regulatory protein |
| M. marinum M | MMAR_5046 | - | 2e-09 | 33.02% (106) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 1e-09 | 31.09% (119) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4584 | - | 3e-67 | 66.84% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 1e-09 | 31.09% (119) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-07 | 27.27% (176) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0901c | - | 5e-11 | 26.23% (183) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5138 | - | 2e-09 | 30.12% (166) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 1e-09 | 28.89% (135) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2070 | - | 7e-12 | 32.46% (114) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4120 | - | 3e-09 | 32.69% (104) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0318 | - | 4e-74 | 72.54% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3587c|M.bovis_AF2122/97 ------------------MDRVAGQVNSRRGELLELAAAMFAERGLRATT
Rv3557c|M.tuberculosis_H37Rv ------------------MDRVAGQVNSRRGELLELAAAMFAERGLRATT
MUL_4120|M.ulcerans_Agy99 ---------------------------------MGLAAVMFAERGLRATT
TH_2070|M.thermoresistible__bu --------------------MTNSGPPTRRDELLELAAQMFAERGLKATT
MSMEG_6009|M.smegmatis_MC2_155 -----------------MAPDTPSQPASRRDELLQLAATMFADRGLKATT
Mflv_4584|M.gilvum_PYR-GCK ----------------------MHDTPSQICDRHPASADLSAEKGPNDSK
Mvan_0318|M.vanbaalenii_PYR-1 ----------------------MRKIPRQISDRLPAAADLFAEKGLNDSK
MMAR_4832|M.marinum_M ----------------------MRKIPAQISERLPAAAELFAERGLNDTK
MAB_0901c|M.abscessus_ATCC_199 -----------MTTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTS
MAV_5138|M.avium_104 ----------------MPADSSTPNGQTRREELLAVATKLFAARGYHGTR
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: : :
Mb3587c|M.bovis_AF2122/97 VRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYR-DIVDSTA
Rv3557c|M.tuberculosis_H37Rv VRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYR-DIVDSTA
MUL_4120|M.ulcerans_Agy99 VRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFARYL-EIVDGEP
TH_2070|M.thermoresistible__bu VRDIADSAGILSGSLYHHFASKEEMVDEVLRGFLDWLFDRYR-SIVETEP
MSMEG_6009|M.smegmatis_MC2_155 VRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLFGRYQ-QILDTAT
Mflv_4584|M.gilvum_PYR-GCK FEDVAAVTGVPKATLYYYFAGKEDILAFLLEDLLKDISEAVT-AIVHTDG
Mvan_0318|M.vanbaalenii_PYR-1 IEDVAAVTGVPKATLYYYFAGKEDILAFLLEDLLKDISEAVT-AIVHTDG
MMAR_4832|M.marinum_M IEDVAATTGIAKATLYYYFAGKEEILAFLLEDVLQHVADEVT-AIVEADG
MAB_0901c|M.abscessus_ATCC_199 MEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFAATE-APDTTTG
MAV_5138|M.avium_104 MDDVADVIGLNKATVYHYYASKSLILYDIYQQAAERTLAAVHDDPSMTAR
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
. .:: *: :.*.: .*. ::
Mb3587c|M.bovis_AF2122/97 NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQ
Rv3557c|M.tuberculosis_H37Rv NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQ
MUL_4120|M.ulcerans_Agy99 NPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSSQPRFSYLEDRNKEQ
TH_2070|M.thermoresistible__bu NPLERFKGLFMASFEAIEHRHAQVVIYQDEAKRLSSQPRFAYVEQRNREQ
MSMEG_6009|M.smegmatis_MC2_155 SPLEKLTGLFMASFEAIEHRHAQVVIYQDEAKRLSDLPQFDFVETRNKEQ
Mflv_4584|M.gilvum_PYR-GCK TGAERLELVIRAQLRAMAQRPAVCRALIGELGRAARMP--AIAEMINTAY
Mvan_0318|M.vanbaalenii_PYR-1 TGAERLELVIRAQLRAMAQRPAVCRALIGELGRAARMP--AIAEMINTAY
MMAR_4832|M.marinum_M TAAQRLHTVINAQLRVMAQRPAVCRALIGELGRAARMP--AIADMITTAY
MAB_0901c|M.abscessus_ATCC_199 PAIDRLENLVKRSIQVLVQELPYVTLLLRIRGNTAAERR---ALARRREF
MAV_5138|M.avium_104 EALYQYTVRLLDQIAANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQV
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
. : . .
Mb3587c|M.bovis_AF2122/97 RKMWVDVLNQGIEEGYFRPDLD-VDLVYRFIRDTTWVSVRWYRPGGPLTA
Rv3557c|M.tuberculosis_H37Rv RKMWVDVLNQGIEEGYFRPDLD-VDLVYRFIRDTTWVSVRWYRPGGPLTA
MUL_4120|M.ulcerans_Agy99 RKMWLDVLNQGIEEGYFRPDLD-VDLVYRFIRDTTWVSVRWYKPGGALTA
TH_2070|M.thermoresistible__bu RKMWVDVLTQGIEEGYFRSDID-VDLVYRFIRDTTWVSVRWYRPGGPLTA
MSMEG_6009|M.smegmatis_MC2_155 RKMWVDILQEGVADGSFRPDLD-VDLVYRFIRDTTWVSVRWYKPGGPLSA
Mflv_4584|M.gilvum_PYR-GCK QQPVEILLIEGARDGSLVAQPDARSTSIALFGAVTINALMYLVTENHLDE
Mvan_0318|M.vanbaalenii_PYR-1 QQPVETLLVEGARDGSLVAQPDARSTSIALFGAVTINALMYLVTENHLDE
MMAR_4832|M.marinum_M FEPVETLLRAGAADGSLVALDKPRAAAIALFGAVTISALTYLITDDALNE
MAB_0901c|M.abscessus_ATCC_199 DDIVGNLVEEACNEGSIRAGVD-PALTSRLIFGTVNSLIEWYRPSRTLSA
MAV_5138|M.avium_104 YEHVHGLIDRGIASGEFYECDS-HVLALGYIG-MTLGAYRWLRPSGRRSA
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAAT-FSDEKPLIPD
. . . : . :
Mb3587c|M.bovis_AF2122/97 QQVGQQYLAIVLGGITKEGV---------
Rv3557c|M.tuberculosis_H37Rv QQVGQQYLAIVLGGITKEGV---------
MUL_4120|M.ulcerans_Agy99 QQVGQKYLAIVLGGIQKEGV---------
TH_2070|M.thermoresistible__bu EEVGRQYLSIVLGGITAGAN---------
MSMEG_6009|M.smegmatis_MC2_155 EQVGQQYLAIVLGGITQSQGDKHA-----
Mflv_4584|M.gilvum_PYR-GCK TVVASTLSAVMFDGLRPRTGDQS------
Mvan_0318|M.vanbaalenii_PYR-1 TVVARTLSAVMFDGLRPRTGDQS------
MMAR_4832|M.marinum_M ELIARTIHDVAFIGLRPR-----------
MAB_0901c|M.abscessus_ATCC_199 DEVADAVATMIFDGLRTRSGQH-------
MAV_5138|M.avium_104 KEIAAEFSTALLRGLIRDEEIRTTSPLGP
MLBr_01070|M.leprae_Br4923 KKVIDTLVHIWLASIYGS-----------
: : .: