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HIFRRALIIACVASLAAFGVAACGSDDSSGGGGGSGGDITVNATSFPDYIDPQLSYTVEGWEVLWNVYTP LLTYRHARGKEGTEVVPALAEALPDISPDGKTYKLKLRPNMKYSDGTPIKASDFTYAIQRLFKTDSGGSV FYNVIAGATEYADGAADTITGITTDDGTGDITIQLTEPNGTFDNLLGLMFAAPIPQSTPLDADATNNPPP ASGPFMFTTVDAPRTLTMERNPQFQTVKDAGADEVADAGVDKITLIENKNQSAQVTDIMQNKVDFMMDPV PSDRLQEVKSRYSDRFRMEDSINTYYMFMNTERAPFNDVRVRQAINYAIDPEALNRIFGGRLHPTQQVLP PGMPGYQEYKLYPGPDMDKARALIAEANPADRDITVWTDDEPDRKRIGEYYHDLLTQLGFNATLKVIAGD VYWTTVGNQSTPDVDTGFADWFQDFPHPDDFFRPLLHGDSILPTNGNNLSRANIAENNAKMDELVTKQIT DEGVEQQYADLDRAYMEQAVWAPYGNEQFTTFLSERMDFDKSYHHLLFKQDFTSFALK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0438 | - | - | 100% (549) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_3773 | - | 9e-31 | 24.15% (501) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1024 | - | 3e-19 | 25.36% (414) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3690c | dppA | 5e-13 | 22.71% (480) | periplasmic dipeptide-binding lipoprotein DppA |
| M. gilvum PYR-GCK | Mflv_2761 | - | 3e-33 | 25.65% (460) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv3666c | dppA | 2e-13 | 22.71% (480) | periplasmic dipeptide-binding lipoprotein DppA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0719 | - | 3e-16 | 24.12% (514) | putative oligopeptide ABC transporter, solute-binding protein |
| M. marinum M | MMAR_5154 | dppA | 4e-13 | 23.11% (502) | periplasmic dipeptide-binding lipoprotein DppA |
| M. avium 104 | MAV_0464 | - | 4e-10 | 21.67% (480) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_0643 | - | 0.0 | 77.37% (548) | extracellular solute-binding protein, family protein 5, |
| M. thermoresistible (build 8) | TH_4152 | - | 7e-25 | 24.14% (435) | PUTATIVE extracellular solute-binding protein, family 5 |
| M. ulcerans Agy99 | MUL_4240 | dppA | 8e-13 | 23.11% (502) | periplasmic dipeptide-binding lipoprotein DppA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0438|M.vanbaalenii_PYR-1 --------------------------------------MHIFRRALIIAC
MSMEG_0643|M.smegmatis_MC2_155 --------------------------------------MIAGRKCLKIAS
Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM
Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM
MMAR_5154|M.marinum_M ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
MAV_0464|M.avium_104 --------------------------------------------------
Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA
TH_4152|M.thermoresistible__bu -------------------------------------------------V
MAB_0719|M.abscessus_ATCC_1997 ---------------------------------------------MVRLR
Mvan_0438|M.vanbaalenii_PYR-1 VASLAAFGVAACGSDDSSGGGGGS---GGDITVNATSFPDYIDPQLSYTV
MSMEG_0643|M.smegmatis_MC2_155 VAAVAVLGVAACGGGGGSGGSSGAANEGGEVNVTMTSFPDYVDPQLSYTM
Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCGGGV-LSPDVVLVNGGEPPNPLIPTGTNDS
Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCGGGV-LSPDVVLVNGGEPPNPLIPTGTNDS
MMAR_5154|M.marinum_M RATLAVVAV-LLAVSPVAACGGGV-LSPDLVLVNGGEPPNPLIPTGTNDS
MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACGGGV-LSPDLVLVNGGEPPNPLIPTGTNDS
MAV_0464|M.avium_104 MAVLATAAAALLVVASLAGCGGGV-LSPDLVVVNGGEPPNPLVPTGTNDS
Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVDLGD-GAGGALIAAIAGEPDQLDPHKTTAY
TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVDLGD-LSG-NLIAAIAGEPDQLDPHKTSAY
MAB_0719|M.abscessus_ATCC_1997 KLAVAASAILVAGCGMGRPPGAID---GEYLTVGTTDRVSTLDPAGAYDN
:.. . : . . : * :
Mvan_0438|M.vanbaalenii_PYR-1 EGWEVLWNVYTPLLTYRHARGKEGTEVVPALAEALPDISPDGKTYKLKLR
MSMEG_0643|M.smegmatis_MC2_155 EGWEVLYNTYVPLLTYKHAKGEEGAEVAPGLAEDMPEVSPDGKTYKLKLR
Mb3690c|M.bovis_AF2122/97 NGGRIIDRLFAGLMSY-----DAVGKPSLEVAQSIESA--DNVNYRITVK
Rv3666c|M.tuberculosis_H37Rv NGGRIIDRLFAGLMSY-----DAVGKPSLEVAQSIESA--DNVNYRITVK
MMAR_5154|M.marinum_M YGGRIIDRLFAGLVSY-----DAKGKPSLEVAQSIDTT--DNVNYRILLK
MUL_4240|M.ulcerans_Agy99 YGGRIIDRLFAGLVSY-----DAKGKPSLEVAQSIDTT--DNVNYRILLK
MAV_0464|M.avium_104 QGGRILDRLFAGLMSY-----DAAGNPAPEVAQSIESG--DNVNYRIVLK
Mflv_2761|M.gilvum_PYR-GCK FSFEVLENVFDTLVEP-----DQDLQMKPALAESWEVSP-DQLTWTFRLR
TH_4152|M.thermoresistible__bu FSFQVLENVFDTLVEP-----DEDLRMRPALAESWQVSA-DQRVWTFRLR
MAB_0719|M.abscessus_ATCC_1997 GSFQVENQVYPFLMNFT----PGTGDLKPDLAAGCGFEN--PTLYRCTLK
. .: . : *: :* : ::
Mvan_0438|M.vanbaalenii_PYR-1 PNMKYSDGTPIKASDFTYAIQR------LFKTDSGGSVFYNVIAGATEYA
MSMEG_0643|M.smegmatis_MC2_155 QNMKYADGTPIKASDFTYAIQR------LFKADSGGSVFFGVIVGANDYA
Mb3690c|M.bovis_AF2122/97 PGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPG
Rv3666c|M.tuberculosis_H37Rv PGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPG
MMAR_5154|M.marinum_M PGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAGEPG
MUL_4240|M.ulcerans_Agy99 PGWGFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAGEPG
MAV_0464|M.avium_104 PGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQSFFSPIDGYDALAA--G
Mflv_2761|M.gilvum_PYR-GCK PGVTFHDGTPLAAEDVVFSYRR--------IIDEQLANSD----------
TH_4152|M.thermoresistible__bu PGVTFHDGSPLTADDVVFSYRR--------IIDEHLTNVD----------
MAB_0719|M.abscessus_ATCC_1997 PGSVFANGHELTSSDVKFSYDR------ERVINDPNGPQS----------
. : :* : : .. : :
Mvan_0438|M.vanbaalenii_PYR-1 DGAADTITGITTDDGTGDITIQLTEPNGTFDNLLGLMFAAPIPQSTPLDA
MSMEG_0643|M.smegmatis_MC2_155 EGKADTITGIQTNDDTGDITINLTEANGTFDNLLGLPFSAPVPPTTPLDT
Mb3690c|M.bovis_AF2122/97 DKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDM
Rv3666c|M.tuberculosis_H37Rv DKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDM
MMAR_5154|M.marinum_M EGKPTTMSGLHVVNNR-EFTVRLRAPTIDFMLSLGHSSFYPLPEAAFKDM
MUL_4240|M.ulcerans_Agy99 EGKPTTMSGLHVVNNR-EFTVRLRAPTIDFMLSLGHSSFYPLPEAAFKDM
MAV_0464|M.avium_104 QPQQTTMTGLRVVNDL-EFTVRLKAPTVDFKLRLGHSAFYPLPQAAFRDM
Mflv_2761|M.gilvum_PYR-GCK --KFSSVQAVEAPDPS-TVVIRVDRPTPNMLTNLGGFKGMAIVSRANVES
TH_4152|M.thermoresistible__bu --RLSAVTEVTAVDPL-TVRITVARPTPNLLTNLGGFKGMAIVQRANVET
MAB_0719|M.abscessus_ATCC_1997 --LLANLDRVETPDDL-TVDFRLKLPNDQTFPQVLATNAGPVIDEEVFPP
: : . : . . : .. : .:
Mvan_0438|M.vanbaalenii_PYR-1 DATNNPPPASGPFMFTTVDAPRTLTMERNPQFQTVKDAGADEVA-DAGVD
MSMEG_0643|M.smegmatis_MC2_155 DATNNPPPGSGPFTITSVDAPHTLVMERNPQFQTVKDAGADEVA-DAHVD
Mb3690c|M.bovis_AF2122/97 AAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPRNK
Rv3666c|M.tuberculosis_H37Rv AAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPRNK
MMAR_5154|M.marinum_M AAFGRNPIGNGPYRLD--SGGEEPAWEHNVKIDLVPNPDYRGNR-KPRNK
MUL_4240|M.ulcerans_Agy99 AAFGRNPIGNGPYRLD--SGGEEPAWEHNVKIDLVPNPDYRGNR-KPRNK
MAV_0464|M.avium_104 AAFGRHPIGNGPYQLA--GGPDGPAWEHNVRIDLRPNPDYHGNR-KPRNK
Mflv_2761|M.gilvum_PYR-GCK GRIATHPVGTGPFSFL--GQKSG------DSISLRANPDYWAG--PPGVA
TH_4152|M.thermoresistible__bu GRIATHPVGTGPFEFR--GARSG------DSITLVANDDHWAG--PPRLN
MAB_0719|M.abscessus_ATCC_1997 DRLLDDDAIARAEPFA--GPYTITSHTKNQLIGLRANPKYVGGLGKPQWD
. : . : : .
Mvan_0438|M.vanbaalenii_PYR-1 KITLIENKNQSAQVTDIMQNKVDFMMDPVPSDRLQEVKSRYSDRFRMEDS
MSMEG_0643|M.smegmatis_MC2_155 KIIVTQNKSNSAQVTDIEQNKTDFMHDPPDADRLPEVKARFGDRFRLEDS
Mb3690c|M.bovis_AF2122/97 GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALTVYQRDLGDHATSGPA
Rv3666c|M.tuberculosis_H37Rv GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALTVYQRDLGDHATSGPA
MMAR_5154|M.marinum_M GLRFEFYANLETAYSDLLSGNLDVLDT-IPSSALTVYGRDLGDNATSGPA
MUL_4240|M.ulcerans_Agy99 GLRFEFYANLETAYSDLLSGNLDVLDT-IPSSALTVYGRDLGDNATSGPA
MAV_0464|M.avium_104 GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALPVYRRDLGERVTAGPA
Mflv_2761|M.gilvum_PYR-GCK GVTFRFIPEPSTALSALQAGEVDWTDS-VPPQRVSQLRDDESLQLTVTPS
TH_4152|M.thermoresistible__bu GVTFRFISEPATALSALQAGEIDWTDA-IPTQRVTQLRNDDSLTLAVTPS
MAB_0719|M.abscessus_ATCC_1997 LIGIKYYTGGENLKIDIENRAIDVAYRSLSPNDIETLRVNPRLSVHEGPG
: . : * .. : .
Mvan_0438|M.vanbaalenii_PYR-1 --INTYYMFMNTERAPFNDVRVR--QAINYAID-PEALNRIFGGRLHPTQ
MSMEG_0643|M.smegmatis_MC2_155 --INTYYFWMNTQQAPFNDVRVR--QAVNYAID-PEALNRVFGGRLHPTQ
Mb3690c|M.bovis_AF2122/97 AINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSPAR
Rv3666c|M.tuberculosis_H37Rv AINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSPAR
MMAR_5154|M.marinum_M AINQTLDTPLRLAHFGGEEGRLRR-LALSAAIDRPQICQQIFNGTRSAAR
MUL_4240|M.ulcerans_Agy99 AINQTLDTPLRLAHFGGEEGRLRR-LALSAAIDRPQICQQIFNGTRSAAR
MAV_0464|M.avium_104 AINQSLDTPLRLPHFGGEEGRLRR-LALSAAINRAQICRQIFADTRSPAR
Mflv_2761|M.gilvum_PYR-GCK --NDYWYLALNQARAPWNDVRVR--QAIAYAIDRDAIVQATSYGTAAANQ
TH_4152|M.thermoresistible__bu --NDYWYLALNHARAPWHDLRVR--RAIAFGIDREAIVTATGYGTATANQ
MAB_0719|M.abscessus_ATCC_1997 GELRYIVFNLKTMPGVTDAQKLAIRRAVASLVDREALSRDVYKGVYTPVY
:. . :: *: :: . .
Mvan_0438|M.vanbaalenii_PYR-1 QVLPPGMPGYQEYKLYPGP---DMDKARALIAEANPADRDITVWTDDEPD
MSMEG_0643|M.smegmatis_MC2_155 QILPPGMPGYEEFTLYPGP---DMDKAKQLIAEANPADRDITVWTDDEPD
Mb3690c|M.bovis_AF2122/97 DFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNA
Rv3666c|M.tuberculosis_H37Rv DFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNA
MMAR_5154|M.marinum_M DFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAYNA
MUL_4240|M.ulcerans_Agy99 DFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAYNA
MAV_0464|M.avium_104 DFTARSLPGFDPNIAGSDALDFDPERARRLWAQADAISAWSGSYPIAYNA
Mflv_2761|M.gilvum_PYR-GCK LAIPEGNPWFTPYDRYREDGEEGLETARDLLRQANAT-----PGDLDMLV
TH_4152|M.thermoresistible__bu LAIPPGDFWYTHYDRYRYD----LDRARALLDEARAAGVDP-PRRLDMLV
MAB_0719|M.abscessus_ATCC_1997 SVVPESMAGSVESFKALYGVKPNVDLARKFLSEAQVAAPVLINLQYN-PD
. . : *: : :*
Mvan_0438|M.vanbaalenii_PYR-1 RKRIGEYYHDLLTQLGFNATLKVIAG---DVYWTTVGNQSTPDVDTGFAD
MSMEG_0643|M.smegmatis_MC2_155 RKRIGEYYHDVLTQLGFNATLKVIAG---DVYWTTIGNQTTPDLDTGFGD
Mb3690c|M.bovis_AF2122/97 DAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAG
Rv3666c|M.tuberculosis_H37Rv DAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAG
MMAR_5154|M.marinum_M DSGHQEWVDTVANSIKNVLGIEAMGAPQPTFAGLRTQITNRTIDTAFRAG
MUL_4240|M.ulcerans_Agy99 DSGHQEWVDAVANSIKNVLGIEAMGAPQPTFAGLRTQITNRTIDTAFRAG
MAV_0464|M.avium_104 DAGHQDWVDAVANGIKNVLGIDALGAPQPTFAGFRTQITNRSIGSAFRSG
Mflv_2761|M.gilvum_PYR-GCK TTEYPETVTAAQIVADNLAPLGITVNIRTVDFATWLDEQNSGNFDMLMMG
TH_4152|M.thermoresistible__bu TGDYPQTVTAAQIIADNVAPLGITVDIRTVDFATWLDEQNNGTFDMLMMG
MAB_0719|M.abscessus_ATCC_1997 HYGGNSSEEYAAVKGQLEASGLFSVDLQSTEWVAYQERRSSDSYPVYQFG
. . .
Mvan_0438|M.vanbaalenii_PYR-1 WFQDFPHPDDFFRPLLHGDSILPTNGNNLSRANIAENNAKMDELVTKQIT
MSMEG_0643|M.smegmatis_MC2_155 WFQDFPHPDDFFRPLINGKSILPTNGNNFSRVAIPELDAKMNELLTQQLT
Mb3690c|M.bovis_AF2122/97 WQGDYPSMIGFLAPLFT-----AGAGSNDVGYINPEFDAALAAAEAAPTL
Rv3666c|M.tuberculosis_H37Rv WRGDYPSMIEFLAPLFT-----AGAGSNDVGYINPEFDAALAAAEAAPTL
MMAR_5154|M.marinum_M WQGDFPSMIEFLAPLYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTL
MUL_4240|M.ulcerans_Agy99 WQGDFPSMIEFLAPLYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTL
MAV_0464|M.avium_104 WQGDYPSMIEFLAPLFA-----TGAGSNDVGYSSPRFDAALATAEAAPDL
Mflv_2761|M.gilvum_PYR-GCK WLGNIDPDDFYYAQHHT-----DGT-SNAQKFSNPEVDRLLDAGRVETDE
TH_4152|M.thermoresistible__bu WLGNIDPDDYYYAQHHT-----DGA-SNAQRFSDPEVDRLLDAARAEPDR
MAB_0719|M.abscessus_ATCC_1997 WFPDFPDPDNYLTPFFMP------DNMLVNHFQNDTITRLITAEVTEPDS
* : : : .
Mvan_0438|M.vanbaalenii_PYR-1 DEGVEQQYADLDRAYME-QAVWAPYGNEQFTTFLSERMDFDKSYHHLLFK
MSMEG_0643|M.smegmatis_MC2_155 DE-TKKGYADLDRAYME-QAVWAPYGNEQLATFLSDRMDFDRSYHHVLFN
Mb3690c|M.bovis_AF2122/97 TESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWNGLPDY
Rv3666c|M.tuberculosis_H37Rv TESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWNGLPDY
MMAR_5154|M.marinum_M QEADRLANVAQRILFHD-MPTIPLWDYIAVVGWSTEVSNVQVTWNGLPDY
MUL_4240|M.ulcerans_Agy99 QEADRLANVAQRILFHD-MPTIPLWDYIAVVGWSTEVSNVQVTWNGLPDY
MAV_0464|M.avium_104 PQAAALANDAQRILFHD-MPVVPLWNYISVVGWSGEVSHVTVTWNGLPDY
Mflv_2761|M.gilvum_PYR-GCK QTRKAGYARAATLIADE-VSYIYLYNPSVIQAWNPALSGYEARRDGAVRF
TH_4152|M.thermoresistible__bu DRRKALYDRAATLIADR-VSYLFLYNPAVVQAWSPDLSGYRARRDAAVRF
MAB_0719|M.abscessus_ATCC_1997 AKRLRIIGQIQDLMARDYISTLPLLTGKQIAVSVKNVDGIKLGPSFKFQF
. .
Mvan_0438|M.vanbaalenii_PYR-1 QDFTSFALK-------
MSMEG_0643|M.smegmatis_MC2_155 QDFTSFALK-------
Mb3690c|M.bovis_AF2122/97 ENIVKA----------
Rv3666c|M.tuberculosis_H37Rv ENIVKA----------
MMAR_5154|M.marinum_M ENLVKA----------
MUL_4240|M.ulcerans_Agy99 ENLVKA----------
MAV_0464|M.avium_104 ENIVKA----------
Mflv_2761|M.gilvum_PYR-GCK RSASLDSDGNV-----
TH_4152|M.thermoresistible__bu RDASLNRDGLNRDGPP
MAB_0719|M.abscessus_ATCC_1997 TPLKKTGGTA------