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ARTAVGAAVLAVCALVLSLTGCNTGERVDLGDGAGGALIAAIAGEPDQLDPHKTTAYFSFEVLENVFDTL VEPDQDLQMKPALAESWEVSPDQLTWTFRLRPGVTFHDGTPLAAEDVVFSYRRIIDEQLANSDKFSSVQA VEAPDPSTVVIRVDRPTPNMLTNLGGFKGMAIVSRANVESGRIATHPVGTGPFSFLGQKSGDSISLRANP DYWAGPPGVAGVTFRFIPEPSTALSALQAGEVDWTDSVPPQRVSQLRDDESLQLTVTPSNDYWYLALNQA RAPWNDVRVRQAIAYAIDRDAIVQATSYGTAAANQLAIPEGNPWFTPYDRYREDGEEGLETARDLLRQAN ATPGDLDMLVTTEYPETVTAAQIVADNLAPLGITVNIRTVDFATWLDEQNSGNFDMLMMGWLGNIDPDDF YYAQHHTDGTSNAQKFSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYIYLYNPSVIQAWNPAL SGYEARRDGAVRFRSASLDSDGNV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2761 | - | - | 100% (515) | extracellular solute-binding protein |
M. gilvum PYR-GCK | Mflv_0119 | - | 7e-26 | 25.45% (503) | extracellular solute-binding protein |
M. gilvum PYR-GCK | Mflv_2258 | - | 7e-10 | 22.07% (290) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1311c | oppA | 8e-15 | 22.03% (522) | periplasmic oligopeptide-binding lipoprotein OppA |
M. tuberculosis H37Rv | Rv1280c | oppA | 8e-15 | 22.03% (522) | periplasmic oligopeptide-binding lipoprotein OppA |
M. leprae Br4923 | MLBr_01121 | - | 1e-12 | 22.14% (411) | putative extracellular solute-binding dependent transport |
M. abscessus ATCC 19977 | MAB_0426 | - | 9e-20 | 25.15% (517) | peptide ABC transporter DppA |
M. marinum M | MMAR_5154 | dppA | 1e-16 | 23.15% (553) | periplasmic dipeptide-binding lipoprotein DppA |
M. avium 104 | MAV_0464 | - | 8e-19 | 24.06% (532) | extracellular solute-binding protein, family protein 5 |
M. smegmatis MC2 155 | MSMEG_4354 | - | 0.0 | 79.29% (507) | dipeptide-binding protein of ABC transport system |
M. thermoresistible (build 8) | TH_4152 | - | 0.0 | 74.46% (505) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4240 | dppA | 9e-17 | 23.62% (542) | periplasmic dipeptide-binding lipoprotein DppA |
M. vanbaalenii PYR-1 | Mvan_3773 | - | 0.0 | 86.61% (508) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1311c|M.bovis_AF2122/97 ------------MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFA Rv1280c|M.tuberculosis_H37Rv ------------MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFA MLBr_01121|M.leprae_Br4923 ------------MIMLSR-------IVAAL-------------------- Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------------------MRTV MSMEG_4354|M.smegmatis_MC2_155 ---------------------------------------------MAGMA TH_4152|M.thermoresistible__bu -------------------------------------------------V MMAR_5154|M.marinum_M ----------------------------------------------MRRM MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM MAV_0464|M.avium_104 -------------------------------------------------M MAB_0426|M.abscessus_ATCC_1997 -----------------------------------------------MRL Mb1311c|M.bovis_AF2122/97 LLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDG Rv1280c|M.tuberculosis_H37Rv LLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDG MLBr_01121|M.leprae_Br4923 ----LVVGLILTGCSASN---RLVPSAASNAALGKTSDINPQDPATLKDG Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGE-RVDLGDGAGGALIAAIAGEPDQLDPHKT--- Mvan_3773|M.vanbaalenii_PYR-1 VLATCVFLAALTGCSPGD-RVDLGAGAADALIAAIAGEPDQLDPHKT--- MSMEG_4354|M.smegmatis_MC2_155 TAWLAALVLVFTACSTGE-RVDLGDEASGNLIAAIAGEPDQLDPQKT--- TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQ-RVDLGD-LSGNLIAAIAGEPDQLDPHKT--- MMAR_5154|M.marinum_M RATLAVVAVLLAVSPVAACGGGVLS--PDLVLVNGGEPPNPLIPTGT--- MUL_4240|M.ulcerans_Agy99 RATLAVVAVLLAVSPVAACGGGVLS--PDLVLVNGGEPPNPLIPTGT--- MAV_0464|M.avium_104 AVLATAAAALLVVASLAGCGGGVLS--PDLVVVNGGEPPNPLVPTGT--- MAB_0426|M.abscessus_ATCC_1997 RRLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNT--- . . . : . * Mb1311c|M.bovis_AF2122/97 GNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDT Rv1280c|M.tuberculosis_H37Rv GNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDT MLBr_01121|M.leprae_Br4923 GNLRLALTDFPANFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDT Mflv_2761|M.gilvum_PYR-GCK -TAYFSFEVLENVFDTLVE----PDQDLQMKPALAESWEVSPD------- Mvan_3773|M.vanbaalenii_PYR-1 -TSYFSFEVLENVFDTLVE----PDGNLQMQPALARAWEVSPD------- MSMEG_4354|M.smegmatis_MC2_155 -SAYFSFEVLENVFDTLVE----PDENLQMQPALAESWEVSPD------- TH_4152|M.thermoresistible__bu -SAYFSFQVLENVFDTLVE----PDEDLRMRPALAESWQVSAD------- MMAR_5154|M.marinum_M -NDSYGGRIIDRLFAGLVSYD----AKGKPSLEVAQSIDTTDN------- MUL_4240|M.ulcerans_Agy99 -NDSYGGRIIDRLFAGLVSYD----AKGKPSLEVAQSIDTTDN------- MAV_0464|M.avium_104 -NDSQGGRILDRLFAGLMSYD----AAGNPAPEVAQSIESGDN------- MAB_0426|M.abscessus_ATCC_1997 -TENQGGRILRSLFTALVEFNN--ETAAVEYTGVAESITSHDN------- . . : * * :..: : Mb1311c|M.bovis_AF2122/97 NYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIHA----ISG Rv1280c|M.tuberculosis_H37Rv NYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIHA----ISG MLBr_01121|M.leprae_Br4923 NYFTSIKLTSTSPQVVTYTINPKAVWSDGTPITWRDIDRQIHA----NSG Mflv_2761|M.gilvum_PYR-GCK ------------QLTWTFRLRPGVTFHDGTPLAAEDVVFSYRR----IID Mvan_3773|M.vanbaalenii_PYR-1 ------------QLTWTFHLRPGVTFHDGTPLTADDVVFSYRR----IID MSMEG_4354|M.smegmatis_MC2_155 ------------QLTWTFHLRDGVRWHDGTPLTADDVVYSYRR----IID TH_4152|M.thermoresistible__bu ------------QRVWTFRLRPGVTFHDGSPLTADDVVFSYRR----IID MMAR_5154|M.marinum_M -------------VNYRILLKPGWRFTDGSPVTAHSFVDAWNYGALSTNA MUL_4240|M.ulcerans_Agy99 -------------VNYRILLKPGWGFTDGSPVTAHSFVDAWNYGALSTNA MAV_0464|M.avium_104 -------------VNYRIVLKPGWRFTDGSPVTAHSFVDAWNYGALSTNA MAB_0426|M.abscessus_ATCC_1997 -------------VNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNA :. : :* *:: . . Mb1311c|M.bovis_AF2122/97 ADKAFEIASSSGAERVASVTRGVDDR--------------QAVVTFAKPY Rv1280c|M.tuberculosis_H37Rv ADKAFEIASSSGAERVASVTRGVDDR--------------QAVVTFAKPY MLBr_01121|M.leprae_Br4923 KNKAFEIAGTNGCERVASIRPGANDR--------------QAIVTFAQPY Mflv_2761|M.gilvum_PYR-GCK EQ----LANSDKFSSVQAVE-APDPS--------------TVVIRVDRPT Mvan_3773|M.vanbaalenii_PYR-1 EQ----LANSDKFSSVAAVD-APDPN--------------TVVIRVDRPT MSMEG_4354|M.smegmatis_MC2_155 EQ----LTNVDKFSAVTDVS-APDPA--------------TVRIVVSHPT TH_4152|M.thermoresistible__bu EH----LTNVDRLSAVTEVT-AVDPL--------------TVRITVARPT MMAR_5154|M.marinum_M QLQQHFFSPIEGYEEVAGEPGEGKP---TTMSGLHVVNNREFTVRLRAPT MUL_4240|M.ulcerans_Agy99 QLQQHFFSPIEGYEEVAGEPGEGKP---TTMSGLHVVNNREFTVRLRAPT MAV_0464|M.avium_104 QLQQSFFSPIDGYDALAA--GQPQQ---TTMTGLRVVNDLEFTVRLKAPT MAB_0426|M.abscessus_ATCC_1997 QGSSSFLANVDGFDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPF :: . . : : . * Mb1311c|M.bovis_AF2122/97 AEWRGMFAGNGMLLPASMTATPEAFNKGQLDGPGPSAGPFVVSALD---- Rv1280c|M.tuberculosis_H37Rv AEWRGMFAGNGMLLPASMTATPEAFNKGQLDGPGPSAGPFVVSALD---- MLBr_01121|M.leprae_Br4923 AEWRGMFAGNGMLLPATMTATPEAFNKGQLDRPGPSAGPFIVSSLD---- Mflv_2761|M.gilvum_PYR-GCK PNMLTNLGG----FKGMAIVSRANVESGRIATHPVGTGPFSFLGQ----- Mvan_3773|M.vanbaalenii_PYR-1 PNMLTNLGG----FKGMAIVSRANVESGRIATQPVGTGPFRFLGQ----- MSMEG_4354|M.smegmatis_MC2_155 PNLLTNLGG----FKGMAIVQRGNVESGQIATHPIGTGPFAFAGR----- TH_4152|M.thermoresistible__bu PNLLTNLGG----FKGMAIVQRANVETGRIATHPVGTGPFEFRGA----- MMAR_5154|M.marinum_M IDFMLSLGHS----SFYPLPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPA MUL_4240|M.ulcerans_Agy99 IDFMLSLGHS----SFYPLPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPA MAV_0464|M.avium_104 VDFKLRLGHS----AFYPLPQAAFRDMAAFGRHPIGNGPYQLAGGPDGPA MAB_0426|M.abscessus_ATCC_1997 AIYPMTLGYT----AFLPLPKAFFRDPVKFGVHPIGNGPFKADG-----D :. : : . **: . Mb1311c|M.bovis_AF2122/97 -RTAQRIVLTRNPRWWGA-RPRLDSITY-LVLDDAARLPALQNNTIDATG Rv1280c|M.tuberculosis_H37Rv -RTAQRIVLTRNPRWWGA-RPRLDSITY-LVLDDAARLPALQNNTIDATG MLBr_01121|M.leprae_Br4923 -RTTQRIVLTHNPKWWGT-PPRLDSITY-LVLDDAARLPALQNNTIDATG Mflv_2761|M.gilvum_PYR-GCK -KSGDSISLRANPDYWAG-PPGVAGVTFRFIPEPSTALSALQAGEVDWTD Mvan_3773|M.vanbaalenii_PYR-1 -KSGDSISLAANPNYWDG-PPGVSGVTYRFISEPSTALSALQAGEIDWTD MSMEG_4354|M.smegmatis_MC2_155 -KSGDSITLKANPHYWGP-EPRVSGVTFRFISEPATALSALQAGEIDWTD TH_4152|M.thermoresistible__bu -RSGDSITLVANDDHWAG-PPRLNGVTFRFISEPATALSALQAGEIDWTD MMAR_5154|M.marinum_M WEHNVKIDLVPNPDYRGNRKPRNKGLRFEFYANLETAYSDLLSGNLDVLD MUL_4240|M.ulcerans_Agy99 WEHNVKIDLVPNPDYRGNRKPRNKGLRFEFYANLETAYSDLLSGNLDVLD MAV_0464|M.avium_104 WEHNVRIDLRPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLD MAB_0426|M.abscessus_ATCC_1997 WVRGVGFTLSRYDQYAGEKKAKAKGLIWRVYTEGLTAYTDMQAGALDIQL : * . .: : . : : . : . :* Mb1311c|M.bovis_AF2122/97 VGTLDQLTIAARTKGISIRRAPGP--SWYHFTLNGAPGSILADKALRLAI Rv1280c|M.tuberculosis_H37Rv VGTLDQLTIAARTKGISIRRAPGP--SWYHFTLNGAPGSILADKALRLAI MLBr_01121|M.leprae_Br4923 VGTLDQLTTAQRTNGISIRRTPAP--RWSHFTFNGAVGSILADQGLRLAV Mflv_2761|M.gilvum_PYR-GCK SVPPQRVSQLRDDESLQLTVTPSN--DYWYLALNQAR-APWNDVRVRQAI Mvan_3773|M.vanbaalenii_PYR-1 SVPPQRVTQLRDDESLELAVTPSN--DYWYLALNEAR-EPWNDVRVRQAV MSMEG_4354|M.smegmatis_MC2_155 SVPPQRVAQLRDDDSLTLAVTPSN--DYWYLALNEAR-APWNDVRVRQAI TH_4152|M.thermoresistible__bu AIPTQRVTQLRNDDSLTLAVTPSN--DYWYLALNHAR-APWHDLRVRRAI MMAR_5154|M.marinum_M TIPSSALTVYGRDLGDNATSGPAAINQTLDTPLRLAHFGGEEGRLRRLAL MUL_4240|M.ulcerans_Agy99 TIPSSALTVYGRDLGDNATSGPAAINQTLDTPLRLAHFGGEEGRLRRLAL MAV_0464|M.avium_104 TIPPSALPVYRRDLGERVTAGPAAINQSLDTPLRLPHFGGEEGRLRRLAL MAB_0426|M.abscessus_ATCC_1997 DLPDAAYENAKAEFGSAYLERPRPDITSLGFPMYDPRYRDVR---VRQAI . . * .: . * *: Mb1311c|M.bovis_AF2122/97 AKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQA Rv1280c|M.tuberculosis_H37Rv AKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQA MLBr_01121|M.leprae_Br4923 SKGIDRRTIAKVVQYGLANNPEPLNNHVYVDGQEGYQDNSGVVGYDPEQA Mflv_2761|M.gilvum_PYR-GCK AYAIDRDAIVQATSYGTAA----ANQLAIPEGNPWFTPYDRYREDGEEGL Mvan_3773|M.vanbaalenii_PYR-1 AYAVDRDAIVQATSYGTAA----VNQLAIPQGNPWFTPYDRYRDDGEQGL MSMEG_4354|M.smegmatis_MC2_155 AYGIDRDAIATATSYRTAA----INQLAIPEGNPWFTSYDRYRFD----L TH_4152|M.thermoresistible__bu AFGIDREAIVTATGYGTAT----ANQLAIPPGDFWYTHYDRYRYD----L MMAR_5154|M.marinum_M SAAIDRPQICQQIFNGTRSAARDFTARSLPGFDPHIPGNEALDFN----P MUL_4240|M.ulcerans_Agy99 SAAIDRPQICQQIFNGTRSAARDFTARSLPGFDPHIPGNEALDFN----P MAV_0464|M.avium_104 SAAINRAQICRQIFADTRSPARDFTARSLPGFDPNIAGSDALDFD----P MAB_0426|M.abscessus_ATCC_1997 SMAIDREAITQVIFSGTRTPATSYGSAVVYGYRKGACG-KLCELH----V : .::* * . Mb1311c|M.bovis_AF2122/97 KRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIG Rv1280c|M.tuberculosis_H37Rv KRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIG MLBr_01121|M.leprae_Br4923 QHELDALGWKLNGQFREKDGRQLVIRYLFYDAQGSREFAQLAQHSLAQIG Mflv_2761|M.gilvum_PYR-GCK ETARDLLRQANAT----PGDLDMLVTTEYPETVT---AAQIVADNLAPLG Mvan_3773|M.vanbaalenii_PYR-1 ETARTLLREAGAQ----PRELDMLVTTEYPETVT---AAQIIADNLAPLG MSMEG_4354|M.smegmatis_MC2_155 DESKRLLDEAGAH----PENLDMLVTSEYPETVT---AAQIIADNLAPLG TH_4152|M.thermoresistible__bu DRARALLDEARAAGVDPPRRLDMLVTGDYPQTVT---AAQIIADNVAPLG MMAR_5154|M.marinum_M QRARQLWAQANAI----SPWSGSYAIAYNADSGHQEWVDTVANSIKNVLG MUL_4240|M.ulcerans_Agy99 QRARQLWAQANAI----SPWSGSYAIAYNADSGHQEWVDAVANSIKNVLG MAV_0464|M.avium_104 ERARRLWAQADAI----SAWSGSYPIAYNADAGHQDWVDAVANGIKNVLG MAB_0426|M.abscessus_ATCC_1997 DEANKLLDEAHFD----RNKPIELWYSS-SSTGALSWVQAIGNQLQSNLK . .: : : Mb1311c|M.bovis_AF2122/97 VKLELQAKS-GSGFFSDYVNVGAFDIAQFGWVGDAFPLSSLTQIYASDG- Rv1280c|M.tuberculosis_H37Rv VKLELQAKS-GSGFFSDYVNVGAFDIAQFGWVGDAFPLSSLTQIYASDG- MLBr_01121|M.leprae_Br4923 VKLELQAKA-GSGFFTNYVNVGAFDIVQFGWVGDAFPLSALTQIYQSDG- Mflv_2761|M.gilvum_PYR-GCK ITVNIRTVD-FATWLDE-QNSGNFDMLMMGWLGNIDPDDFYYAQHHTDG- Mvan_3773|M.vanbaalenii_PYR-1 ISVKIRTVD-FATWLDE-QNSGNFDMLMMGWLGNIDPDDFYYAQHHTDG- MSMEG_4354|M.smegmatis_MC2_155 ISVNIRTVD-FATWLDE-QNTGNFDMLMMGWLGNIDPDDFYYAQHHSNG- TH_4152|M.thermoresistible__bu ITVDIRTVD-FATWLDE-QNNGTFDMLMMGWLGNIDPDDYYYAQHHTDG- MMAR_5154|M.marinum_M IEAMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFPSMIEFLAPLYGTG- MUL_4240|M.ulcerans_Agy99 IEAMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFPSMIEFLAPLYGTG- MAV_0464|M.avium_104 IDALGAPQPTFAGFRTQITNRSIGSAFRSGWQGDYPSMIEFLAPLFATG- MAB_0426|M.abscessus_ATCC_1997 VPYLLKSLP-WSQFLPLQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVA : . : . ** : . Mb1311c|M.bovis_AF2122/97 ----ESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSL Rv1280c|M.tuberculosis_H37Rv ----ESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSL MLBr_01121|M.leprae_Br4923 ----ESNFGKISSPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSL Mflv_2761|M.gilvum_PYR-GCK ----TSNAQKFSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYI Mvan_3773|M.vanbaalenii_PYR-1 ----TSNAQKFSDPEVDRLLDASRVETDEAARKEQYAGAATLIADKVSYI MSMEG_4354|M.smegmatis_MC2_155 ----TSNAQKFSDPEVDRLLDAGRVETDTAERKDVYARAATRIADEVSYI TH_4152|M.thermoresistible__bu ----ASNAQRFSDPEVDRLLDAARAEPDRDRRKALYDRAATLIADRVSYL MMAR_5154|M.marinum_M ---AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHDMPTI MUL_4240|M.ulcerans_Agy99 ---AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHDMPTI MAV_0464|M.avium_104 ---AGSNDVGYSSPRFDAALATAEAAPDLPQAAALANDAQRILFHDMPVV MAB_0426|M.abscessus_ATCC_1997 LPPNGSNYVFYSNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAA ** .. .* : . : Mb1311c|M.bovis_AF2122/97 PLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR-------- Rv1280c|M.tuberculosis_H37Rv PLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR-------- MLBr_01121|M.leprae_Br4923 PLTQSPGDVAVRSTLANFGAAGFGDLNYTAIGFMQN-------- Mflv_2761|M.gilvum_PYR-GCK YLYNPSVIQAWNPALSGYEARRDGAVRFRSASLDSDGNV----- Mvan_3773|M.vanbaalenii_PYR-1 YLYNPSVIQAWNPALSGYEARRDGAVRFRSATFGADGGA----- MSMEG_4354|M.smegmatis_MC2_155 YLYNPSVIQAWSNDLSGYVARRDGAIRFRTADLGRGGPE----- TH_4152|M.thermoresistible__bu FLYNPAVVQAWSPDLSGYRARRDAAVRFRDASLNRDGLNRDGPP MMAR_5154|M.marinum_M PLWDYIAVVGWSTEVSNVQVTWNGLPDYENLVKA---------- MUL_4240|M.ulcerans_Agy99 PLWDYIAVVGWSTEVSNVQVTWNGLPDYENLVKA---------- MAV_0464|M.avium_104 PLWNYISVVGWSGEVSHVTVTWNGLPDYENIVKA---------- MAB_0426|M.abscessus_ATCC_1997 PLFYEVNQAVHSKRVRNVKIGIQDCIEYADVEVVQ--------- * : :