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MVRLRKLAVAASAILVAGCGMGRPPGAIDGEYLTVGTTDRVSTLDPAGAYDNGSFQVENQVYPFLMNFTP GTGDLKPDLAAGCGFENPTLYRCTLKPGSVFANGHELTSSDVKFSYDRERVINDPNGPQSLLANLDRVET PDDLTVDFRLKLPNDQTFPQVLATNAGPVIDEEVFPPDRLLDDDAIARAEPFAGPYTITSHTKNQLIGLR ANPKYVGGLGKPQWDLIGIKYYTGGENLKIDIENRAIDVAYRSLSPNDIETLRVNPRLSVHEGPGGELRY IVFNLKTMPGVTDAQKLAIRRAVASLVDREALSRDVYKGVYTPVYSVVPESMAGSVESFKALYGVKPNVD LARKFLSEAQVAAPVLINLQYNPDHYGGNSSEEYAAVKGQLEASGLFSVDLQSTEWVAYQERRSSDSYPV YQFGWFPDFPDPDNYLTPFFMPDNMLVNHFQNDTITRLITAEVTEPDSAKRLRIIGQIQDLMARDYISTL PLLTGKQIAVSVKNVDGIKLGPSFKFQFTPLKKTGGTA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0719 | - | - | 100% (528) | putative oligopeptide ABC transporter, solute-binding protein |
M. abscessus ATCC 19977 | MAB_0426 | - | 1e-15 | 22.87% (551) | peptide ABC transporter DppA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3690c | dppA | 4e-09 | 20.97% (472) | periplasmic dipeptide-binding lipoprotein DppA |
M. gilvum PYR-GCK | Mflv_2761 | - | 1e-17 | 22.22% (468) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv3666c | dppA | 4e-09 | 20.97% (472) | periplasmic dipeptide-binding lipoprotein DppA |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | - | - | - | - | - |
M. avium 104 | MAV_0464 | - | 1e-12 | 20.57% (457) | extracellular solute-binding protein, family protein 5 |
M. smegmatis MC2 155 | MSMEG_0643 | - | 9e-18 | 24.44% (491) | extracellular solute-binding protein, family protein 5, |
M. thermoresistible (build 8) | TH_4152 | - | 7e-14 | 22.13% (488) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4240 | dppA | 5e-05 | 19.55% (491) | periplasmic dipeptide-binding lipoprotein DppA |
M. vanbaalenii PYR-1 | Mvan_3773 | - | 4e-16 | 22.62% (473) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM MAV_0464|M.avium_104 -------------------------------------------------- MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------------------MRTV TH_4152|M.thermoresistible__bu -------------------------------------------------V MSMEG_0643|M.smegmatis_MC2_155 ----------------------------------------MIAGRKCLKI MAB_0719|M.abscessus_ATCC_1997 ---------------------------------------------MVRLR Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCG---GGVLSPDVVLVNGGEPPNPLIPTGTN Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCG---GGVLSPDVVLVNGGEPPNPLIPTGTN MAV_0464|M.avium_104 MAVLATAAAALLVVASLAGCG---GGVLSPDLVVVNGGEPPNPLVPTGTN MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACG---GGVLSPDLVLVNGGEPPNPLIPTGTN Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVD---LGDGAGGALIAAIAGEPDQLDPHKTT Mvan_3773|M.vanbaalenii_PYR-1 VLATCVFLAALTGCSPGDRVD---LGAGAADALIAAIAGEPDQLDPHKTT TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVD---LGD-LSGNLIAAIAGEPDQLDPHKTS MSMEG_0643|M.smegmatis_MC2_155 ASVAAVAVLGVAACGGGGGSGGSSGAANEGGEVNVTMTSFPDYVDPQLSY MAB_0719|M.abscessus_ATCC_1997 KLAVAASAILVAGCGMGRPPG-----AIDGEYLTVGTTDRVSTLDPAGAY .. . : . . : * : Mb3690c|M.bovis_AF2122/97 DSNGGRIIDRLFAGLMSYDAV-----GKPSLEVAQSI-ESA-DNVNYRIT Rv3666c|M.tuberculosis_H37Rv DSNGGRIIDRLFAGLMSYDAV-----GKPSLEVAQSI-ESA-DNVNYRIT MAV_0464|M.avium_104 DSQGGRILDRLFAGLMSYDAA-----GNPAPEVAQSI-ESG-DNVNYRIV MUL_4240|M.ulcerans_Agy99 DSYGGRIIDRLFAGLVSYDAK-----GKPSLEVAQSI-DTT-DNVNYRIL Mflv_2761|M.gilvum_PYR-GCK AYFSFEVLENVFDTLVEPDQD-----LQMKPALAESW-EVSPDQLTWTFR Mvan_3773|M.vanbaalenii_PYR-1 SYFSFEVLENVFDTLVEPDGN-----LQMQPALARAW-EVSPDQLTWTFH TH_4152|M.thermoresistible__bu AYFSFQVLENVFDTLVEPDED-----LRMRPALAESW-QVSADQRVWTFR MSMEG_0643|M.smegmatis_MC2_155 TMEGWEVLYNTYVPLLTYKHAKGEEGAEVAPGLAEDMPEVSPDGKTYKLK MAB_0719|M.abscessus_ATCC_1997 DNGSFQVENQVYPFLMNFTPG----TGDLKPDLAAGC--GFENPTLYRCT . .: . : *: :* : : Mb3690c|M.bovis_AF2122/97 VKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGA Rv3666c|M.tuberculosis_H37Rv VKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGA MAV_0464|M.avium_104 LKPGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQSFFSPIDGYDALA-- MUL_4240|M.ulcerans_Agy99 LKPGWGFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAGE Mflv_2761|M.gilvum_PYR-GCK LRPGVTFHDGTPLAAEDVVFSYRR--------IIDEQLANSD-------- Mvan_3773|M.vanbaalenii_PYR-1 LRPGVTFHDGTPLTADDVVFSYRR--------IIDEQLANSD-------- TH_4152|M.thermoresistible__bu LRPGVTFHDGSPLTADDVVFSYRR--------IIDEHLTNVD-------- MSMEG_0643|M.smegmatis_MC2_155 LRQNMKYADGTPIKASDFTYAIQR------LFKADSGGSVFFGVIVGAND MAB_0719|M.abscessus_ATCC_1997 LKPGSVFANGHELTSSDVKFSYDR------ERVINDPNGPQS-------- :: . : :* : : .. : : Mb3690c|M.bovis_AF2122/97 PGDKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFR Rv3666c|M.tuberculosis_H37Rv PGDKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFR MAV_0464|M.avium_104 AGQPQQTTMTGLRVVNDL-EFTVRLKAPTVDFKLRLGHSAFYPLPQAAFR MUL_4240|M.ulcerans_Agy99 PGEGKPTTMSGLHVVNNR-EFTVRLRAPTIDFMLSLGHSSFYPLPEAAFK Mflv_2761|M.gilvum_PYR-GCK ----KFSSVQAVEAPDPS-TVVIRVDRPTPNMLTNLGGFKGMAIVSRANV Mvan_3773|M.vanbaalenii_PYR-1 ----KFSSVAAVDAPDPN-TVVIRVDRPTPNMLTNLGGFKGMAIVSRANV TH_4152|M.thermoresistible__bu ----RLSAVTEVTAVDPL-TVRITVARPTPNLLTNLGGFKGMAIVQRANV MSMEG_0643|M.smegmatis_MC2_155 YAEGKADTITGIQTNDDTGDITINLTEANGTFDNLLGLPFSAPVPPTTPL MAB_0719|M.abscessus_ATCC_1997 ----LLANLDRVETPDDL-TVDFRLKLPNDQTFPQVLATNAGPVIDEEVF : : . : . . : .. : .: Mb3690c|M.bovis_AF2122/97 DMAAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPR Rv3666c|M.tuberculosis_H37Rv DMAAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPR MAV_0464|M.avium_104 DMAAFGRHPIGNGPYQLA--GGPDGPAWEHNVRIDLRPNPDYHGNR-KPR MUL_4240|M.ulcerans_Agy99 DMAAFGRNPIGNGPYRLD--SGGEEPAWEHNVKIDLVPNPDYRGNR-KPR Mflv_2761|M.gilvum_PYR-GCK ESGRIATHPVGTGPFSFL--GQKSG------DSISLRANPDYWAG--PPG Mvan_3773|M.vanbaalenii_PYR-1 ESGRIATQPVGTGPFRFL--GQKSG------DSISLAANPNYWDG--PPG TH_4152|M.thermoresistible__bu ETGRIATHPVGTGPFEFR--GARSG------DSITLVANDDHWAG--PPR MSMEG_0643|M.smegmatis_MC2_155 DTDATNNPPPGSGPFTITSVDAPHTLVMERNPQFQTVKDAGADEVA-DAH MAB_0719|M.abscessus_ATCC_1997 PPDRLLDDDAIARAEPFA--GPYTITSHTKNQLIGLRANPKYVGGLGKPQ . : . : : . Mb3690c|M.bovis_AF2122/97 NKGLRFEFYANLDTAYADLLSGNLDVLDTIP-PSALTVYQRDLGDHATSG Rv3666c|M.tuberculosis_H37Rv NKGLRFEFYANLDTAYADLLSGNLDVLDTIP-PSALTVYQRDLGDHATSG MAV_0464|M.avium_104 NKGLRFEFYANLDTAYADLLSGNLDVLDTIP-PSALPVYRRDLGERVTAG MUL_4240|M.ulcerans_Agy99 NKGLRFEFYANLETAYSDLLSGNLDVLDTIP-SSALTVYGRDLGDNATSG Mflv_2761|M.gilvum_PYR-GCK VAGVTFRFIPEPSTALSALQAGEVDWTDSVP-PQRVSQLRDDESLQLTVT Mvan_3773|M.vanbaalenii_PYR-1 VSGVTYRFISEPSTALSALQAGEIDWTDSVP-PQRVTQLRDDESLELAVT TH_4152|M.thermoresistible__bu LNGVTFRFISEPATALSALQAGEIDWTDAIP-TQRVTQLRNDDSLTLAVT MSMEG_0643|M.smegmatis_MC2_155 VDKIIVTQNKSNSAQVTDIEQNKTDFMHDPPDADRLPEVKARFGDRFRLE MAB_0719|M.abscessus_ATCC_1997 WDLIGIKYYTGGENLKIDIENRAIDVAYRSLSPNDIETLRVNPRLSVHEG : : * .. : Mb3690c|M.bovis_AF2122/97 PAAINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSP Rv3666c|M.tuberculosis_H37Rv PAAINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSP MAV_0464|M.avium_104 PAAINQSLDTPLRLPHFGGEEGRLRR-LALSAAINRAQICRQIFADTRSP MUL_4240|M.ulcerans_Agy99 PAAINQTLDTPLRLAHFGGEEGRLRR-LALSAAIDRPQICQQIFNGTRSA Mflv_2761|M.gilvum_PYR-GCK PS--NDYWYLALNQARAPWNDVRVR--QAIAYAIDRDAIVQATSYGTAAA Mvan_3773|M.vanbaalenii_PYR-1 PS--NDYWYLALNEAREPWNDVRVR--QAVAYAVDRDAIVQATSYGTAAV TH_4152|M.thermoresistible__bu PS--NDYWYLALNHARAPWHDLRVR--RAIAFGIDREAIVTATGYGTATA MSMEG_0643|M.smegmatis_MC2_155 DS--INTYYFWMNTQQAPFNDVRVR--QAVNYAIDPEALN-RVFGGRLHP MAB_0719|M.abscessus_ATCC_1997 PGGELRYIVFNLKTMPGVTDAQKLAIRRAVASLVDREALSRDVYKGVYTP . :. . :: *: :: : . Mb3690c|M.bovis_AF2122/97 ARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAY Rv3666c|M.tuberculosis_H37Rv ARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAY MAV_0464|M.avium_104 ARDFTARSLPGFDPNIAGSDALDFDPERARRLWAQADAISAWSGSYPIAY MUL_4240|M.ulcerans_Agy99 ARDFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAY Mflv_2761|M.gilvum_PYR-GCK NQLAIPEGNPWFTPYDRYREDGEEGLETARDLLRQANAT-----PGDLDM Mvan_3773|M.vanbaalenii_PYR-1 NQLAIPQGNPWFTPYDRYRDDGEQGLETARTLLREAGAQ-----PRELDM TH_4152|M.thermoresistible__bu NQLAIPPGDFWYTHYDRYRYD----LDRARALLDEARAAGVDP-PRRLDM MSMEG_0643|M.smegmatis_MC2_155 TQQILPPGMPGYEEFTLYPGP---DMDKAKQLIAEANPA-----DRDITV MAB_0719|M.abscessus_ATCC_1997 VYSVVPESMAGSVESFKALYGVKPNVDLARKFLSEAQVAAPVLINLQYNP . . : *: : :* Mb3690c|M.bovis_AF2122/97 NADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFR Rv3666c|M.tuberculosis_H37Rv NADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFR MAV_0464|M.avium_104 NADAGHQDWVDAVANGIKNVLGIDALGAPQPTFAGFRTQITNRSIGSAFR MUL_4240|M.ulcerans_Agy99 NADSGHQEWVDAVANSIKNVLGIEAMGAPQPTFAGLRTQITNRTIDTAFR Mflv_2761|M.gilvum_PYR-GCK LVTTEYPETVTAAQIVADNLAPLGITVNIRTVDFATWLDEQNSGNFDMLM Mvan_3773|M.vanbaalenii_PYR-1 LVTTEYPETVTAAQIIADNLAPLGISVKIRTVDFATWLDEQNSGNFDMLM TH_4152|M.thermoresistible__bu LVTGDYPQTVTAAQIIADNVAPLGITVDIRTVDFATWLDEQNNGTFDMLM MSMEG_0643|M.smegmatis_MC2_155 WTD-DEPDRKRIGEYYHDVLTQLGFNATLKVIAGDVYWTTIGNQTTPDLD MAB_0719|M.abscessus_ATCC_1997 DHYGGNSSEEYAAVKGQLEASGL-FSVDLQSTEWVAYQERRSSDSYPVYQ . : : . Mb3690c|M.bovis_AF2122/97 AG---WQGDYPSMIGFLAPLFT-----AGAGSNDVGYINPEFDAALAAAE Rv3666c|M.tuberculosis_H37Rv AG---WRGDYPSMIEFLAPLFT-----AGAGSNDVGYINPEFDAALAAAE MAV_0464|M.avium_104 SG---WQGDYPSMIEFLAPLFA-----TGAGSNDVGYSSPRFDAALATAE MUL_4240|M.ulcerans_Agy99 AG---WQGDFPSMIEFLAPLYG-----TGAGSNDVGYSNQEFDDALAAAA Mflv_2761|M.gilvum_PYR-GCK MG---WLGNIDPDDFYYAQHHT-----DGT-SNAQKFSNPEVDRLLDAGR Mvan_3773|M.vanbaalenii_PYR-1 MG---WLGNIDPDDFYYAQHHT-----DGT-SNAQKFSDPEVDRLLDASR TH_4152|M.thermoresistible__bu MG---WLGNIDPDDYYYAQHHT-----DGA-SNAQRFSDPEVDRLLDAAR MSMEG_0643|M.smegmatis_MC2_155 TGFGDWFQDFPHPDDFFRPLINGKSILPTNGNNFSRVAIPELDAKMNELL MAB_0719|M.abscessus_ATCC_1997 FG---WFPDFPDPDNYLTPFFMP------DNMLVNHFQNDTITRLITAEV * * : : . : Mb3690c|M.bovis_AF2122/97 AAPTLTESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWN Rv3666c|M.tuberculosis_H37Rv AAPTLTESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWN MAV_0464|M.avium_104 AAPDLPQAAALANDAQRILFHD-MPVVPLWNYISVVGWSGEVSHVTVTWN MUL_4240|M.ulcerans_Agy99 AAPTLQEADRLANVAQRILFHD-MPTIPLWDYIAVVGWSTEVSNVQVTWN Mflv_2761|M.gilvum_PYR-GCK VETDEQTRKAGYARAATLIADE-VSYIYLYNPSVIQAWNPALSGYEARRD Mvan_3773|M.vanbaalenii_PYR-1 VETDEAARKEQYAGAATLIADK-VSYIYLYNPSVIQAWNPALSGYEARRD TH_4152|M.thermoresistible__bu AEPDRDRRKALYDRAATLIADR-VSYLFLYNPAVVQAWSPDLSGYRARRD MSMEG_0643|M.smegmatis_MC2_155 TQQLTDETKKGYADLDRAYMEQ-AVWAPYGNEQLATFLSDRMDFDRSYHH MAB_0719|M.abscessus_ATCC_1997 TEPDSAKRLRIIGQIQDLMARDYISTLPLLTGKQIAVSVKNVDGIKLGPS . :. Mb3690c|M.bovis_AF2122/97 GLPDYENIVKA---------- Rv3666c|M.tuberculosis_H37Rv GLPDYENIVKA---------- MAV_0464|M.avium_104 GLPDYENIVKA---------- MUL_4240|M.ulcerans_Agy99 GLPDYENLVKA---------- Mflv_2761|M.gilvum_PYR-GCK GAVRFRSASLDSDGNV----- Mvan_3773|M.vanbaalenii_PYR-1 GAVRFRSATFGADGGA----- TH_4152|M.thermoresistible__bu AAVRFRDASLNRDGLNRDGPP MSMEG_0643|M.smegmatis_MC2_155 VLFNQDFTSFALK-------- MAB_0719|M.abscessus_ATCC_1997 FKFQFTPLKKTGGTA------