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RRMRATLAVVAVLLAVSPVAACGGGVLSPDLVLVNGGEPPNPLIPTGTNDSYGGRIIDRLFAGLVSYDAK GKPSLEVAQSIDTTDNVNYRILLKPGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVA GEPGEGKPTTMSGLHVVNNREFTVRLRAPTIDFMLSLGHSSFYPLPEAAFKDMAAFGRNPIGNGPYRLDS GGEEPAWEHNVKIDLVPNPDYRGNRKPRNKGLRFEFYANLETAYSDLLSGNLDVLDTIPSSALTVYGRDL GDNATSGPAAINQTLDTPLRLAHFGGEEGRLRRLALSAAIDRPQICQQIFNGTRSAARDFTARSLPGFDP HIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAYNADSGHQEWVDTVANSIKNVLGIEAMGAPQPTFA GLRTQITNRTIDTAFRAGWQGDFPSMIEFLAPLYGTGAGSNDVGYSNQEFDDALAAAAAAPTLQEADRLA NVAQRILFHDMPTIPLWDYIAVVGWSTEVSNVQVTWNGLPDYENLVKA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5154 | dppA | - | 100% (539) | periplasmic dipeptide-binding lipoprotein DppA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3690c | dppA | 0.0 | 82.59% (540) | periplasmic dipeptide-binding lipoprotein DppA |
| M. gilvum PYR-GCK | Mflv_2761 | - | 9e-17 | 23.15% (553) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv3666c | dppA | 0.0 | 82.41% (540) | periplasmic dipeptide-binding lipoprotein DppA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0426 | - | 1e-74 | 34.38% (541) | peptide ABC transporter DppA |
| M. avium 104 | MAV_0464 | - | 0.0 | 78.60% (528) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_4545 | - | 1e-12 | 23.72% (607) | extracellular solute-binding protein, family protein 5 |
| M. thermoresistible (build 8) | TH_4152 | - | 1e-17 | 24.86% (527) | PUTATIVE extracellular solute-binding protein, family 5 |
| M. ulcerans Agy99 | MUL_4240 | dppA | 0.0 | 99.63% (539) | periplasmic dipeptide-binding lipoprotein DppA |
| M. vanbaalenii PYR-1 | Mvan_3773 | - | 8e-14 | 23.26% (374) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA
Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------------------MRTV
TH_4152|M.thermoresistible__bu -------------------------------------------------V
MMAR_5154|M.marinum_M ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM
Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM
MAV_0464|M.avium_104 --------------------------------------------------
MAB_0426|M.abscessus_ATCC_1997 ----------------------------------------------MRLR
MSMEG_4545|M.smegmatis_MC2_155 -------------------------------------MKTTRRVLGTLIA
Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVDLGDGAGGALIAAIAGEPDQLDPHKTTAYF
Mvan_3773|M.vanbaalenii_PYR-1 VLATCVFLAALTGCSPGDRVDLGAGAADALIAAIAGEPDQLDPHKTTSYF
TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVDLGD-LSGNLIAAIAGEPDQLDPHKTSAYF
MMAR_5154|M.marinum_M RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGEPPNPLIPTGTNDSY
MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGEPPNPLIPTGTNDSY
Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSN
Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSN
MAV_0464|M.avium_104 MAVLATAAAALLVVASLAGCGGGVLSPDLVVVNGGEPPNPLVPTGTNDSQ
MAB_0426|M.abscessus_ATCC_1997 RLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNTTENQ
MSMEG_4545|M.smegmatis_MC2_155 TTALVVAACGTNTSESASTADPDSLYGGTLRIASVEDIDALDPLIAYSAE
. . . . * * :
Mflv_2761|M.gilvum_PYR-GCK SFEVLENVFDTLVEPDQ-------DLQMKPALAESWEVSP-DQLTWTFRL
Mvan_3773|M.vanbaalenii_PYR-1 SFEVLENVFDTLVEPDG-------NLQMQPALARAWEVSP-DQLTWTFHL
TH_4152|M.thermoresistible__bu SFQVLENVFDTLVEPDE-------DLRMRPALAESWQVSA-DQRVWTFRL
MMAR_5154|M.marinum_M GGRIIDRLFAGLVSYD---------AKGKPSLEVAQSIDTTDNVNYRILL
MUL_4240|M.ulcerans_Agy99 GGRIIDRLFAGLVSYD---------AKGKPSLEVAQSIDTTDNVNYRILL
Mb3690c|M.bovis_AF2122/97 GGRIIDRLFAGLMSYD---------AVGKPSLEVAQSIESADNVNYRITV
Rv3666c|M.tuberculosis_H37Rv GGRIIDRLFAGLMSYD---------AVGKPSLEVAQSIESADNVNYRITV
MAV_0464|M.avium_104 GGRILDRLFAGLMSYD---------AAGNPAPEVAQSIESGDNVNYRIVL
MAB_0426|M.abscessus_ATCC_1997 GGRILRSLFTALVEFNN-------ETAAVEYTGVAESITSHDNVNWTIKL
MSMEG_4545|M.smegmatis_MC2_155 SWQVIRATTRQLVTYPGSKEGIGDDTTVVPDLAESWDVSP-DRKTYTFHL
. .:: *: : .: . *. : : :
Mflv_2761|M.gilvum_PYR-GCK RPGVTFHDGT--PLAAEDVVFSYRR---------IIDEQLANSDKFSSVQ
Mvan_3773|M.vanbaalenii_PYR-1 RPGVTFHDGT--PLTADDVVFSYRR---------IIDEQLANSDKFSSVA
TH_4152|M.thermoresistible__bu RPGVTFHDGS--PLTADDVVFSYRR---------IIDEHLTNVDRLSAVT
MMAR_5154|M.marinum_M KPGWRFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGYEEVA
MUL_4240|M.ulcerans_Agy99 KPGWGFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGYEEVA
Mb3690c|M.bovis_AF2122/97 KPGWKFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGFDDVA
Rv3666c|M.tuberculosis_H37Rv KPGWKFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGFDDVA
MAV_0464|M.avium_104 KPGWRFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQSFFSPIDGYDALA
MAB_0426|M.abscessus_ATCC_1997 KPGWTFHNGE--PVTAQSYVDAWNYTA-LSTNAQGSSSFLANVDGFDDLQ
MSMEG_4545|M.smegmatis_MC2_155 RDNITFSGASNREITAHDFVYAVKRFPDPNAQVSAITYFNATFDGFEEYA
: . * .. ::*.. * : . : : .
Mflv_2761|M.gilvum_PYR-GCK AVEAPDPS------------------------TVVIRVDRPTPNMLTNLG
Mvan_3773|M.vanbaalenii_PYR-1 AVDAPDPN------------------------TVVIRVDRPTPNMLTNLG
TH_4152|M.thermoresistible__bu EVTAVDPL------------------------TVRITVARPTPNLLTNLG
MMAR_5154|M.marinum_M GEPGEGKP------------TTMSGLHVVNNREFTVRLRAPTIDFMLSLG
MUL_4240|M.ulcerans_Agy99 GEPGEGKP------------TTMSGLHVVNNREFTVRLRAPTIDFMLSLG
Mb3690c|M.bovis_AF2122/97 GAPGDKSR------------TTMSGLRVVNDLEFTVRLKAPTIDFTLRLG
Rv3666c|M.tuberculosis_H37Rv GAPGDKSR------------TTMSGLRVVNDLEFTVRLKAPTIDFTLRLG
MAV_0464|M.avium_104 A--GQPQQ------------TTMTGLRVVNDLEFTVRLKAPTVDFKLRLG
MAB_0426|M.abscessus_ATCC_1997 GDPAHKIAP---------RATQMRGLHVVDDVTFTVRLNTPFAIYPMTLG
MSMEG_4545|M.smegmatis_MC2_155 AEFAKVPTGDLAAVKQFIDTHEIRGFKALDDKTLQLTLTEPASDILDILT
. . : : * *
Mflv_2761|M.gilvum_PYR-GCK GFKGMAIVSRA----NVESGRIATHPVGTGPFSFLG------QKSGDSIS
Mvan_3773|M.vanbaalenii_PYR-1 GFKGMAIVSRA----NVESGRIATQPVGTGPFRFLG------QKSGDSIS
TH_4152|M.thermoresistible__bu GFKGMAIVQRA----NVETGRIATHPVGTGPFEFRG------ARSGDSIT
MMAR_5154|M.marinum_M HSSFYPLPEAA----FKDMAAFGRNPIGNGPYRLDSGGEEPAWEHNVKID
MUL_4240|M.ulcerans_Agy99 HSSFYPLPEAA----FKDMAAFGRNPIGNGPYRLDSGGEEPAWEHNVKID
Mb3690c|M.bovis_AF2122/97 HSSFYPLPDSA----FRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRID
Rv3666c|M.tuberculosis_H37Rv HSSFYPLPDSA----FRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRID
MAV_0464|M.avium_104 HSAFYPLPQAA----FRDMAAFGRHPIGNGPYQLAGGPDGPAWEHNVRID
MAB_0426|M.abscessus_ATCC_1997 YTAFLPLPKAF----FRDPVKFGVHPIGNGPFKADG-----DWVRGVGFT
MSMEG_4545|M.smegmatis_MC2_155 LNFVTPLPEEVTSKYFADSLEFRKNYVSSGPYHIES------YDQGKQLT
.: . : : : :..**: . . :
Mflv_2761|M.gilvum_PYR-GCK LRANPDYWAG-PPGVAGVTFRFIP----EPSTALSALQAGEVDWTD---S
Mvan_3773|M.vanbaalenii_PYR-1 LAANPNYWDG-PPGVSGVTYRFIS----EPSTALSALQAGEIDWTD---S
TH_4152|M.thermoresistible__bu LVANDDHWAG-PPRLNGVTFRFIS----EPATALSALQAGEIDWTD---A
MMAR_5154|M.marinum_M LVPNPDYRGNRKPRNKGLRFEFYA----NLETAYSDLLSGNLDVLD---T
MUL_4240|M.ulcerans_Agy99 LVPNPDYRGNRKPRNKGLRFEFYA----NLETAYSDLLSGNLDVLD---T
Mb3690c|M.bovis_AF2122/97 LVPNPDYHGNRKPRNKGLRFEFYA----NLDTAYADLLSGNLDVLD---T
Rv3666c|M.tuberculosis_H37Rv LVPNPDYHGNRKPRNKGLRFEFYA----NLDTAYADLLSGNLDVLD---T
MAV_0464|M.avium_104 LRPNPDYHGNRKPRNKGLRFEFYA----NLDTAYADLLSGNLDVLD---T
MAB_0426|M.abscessus_ATCC_1997 LSRYDQYAGEKKAKAKGLIWRVYT----EGLTAYTDMQAGALDIQL---D
MSMEG_4545|M.smegmatis_MC2_155 LARVPEYNSEGDPRKAYADKIVFDTTVASADAASQQLQTGTADIALYVRS
* :: . . . :* : :* *
Mflv_2761|M.gilvum_PYR-GCK VPPQRVSQLRDDESLQLTVTPSNDYWYLALN----QARAPWNDVR---VR
Mvan_3773|M.vanbaalenii_PYR-1 VPPQRVTQLRDDESLELAVTPSNDYWYLALN----EAREPWNDVR---VR
TH_4152|M.thermoresistible__bu IPTQRVTQLRNDDSLTLAVTPSNDYWYLALN----HARAPWHDLR---VR
MMAR_5154|M.marinum_M IPSSALTVYGRDLGDNATSGPAAINQTLDTP----LRLAHFGGEEGRLRR
MUL_4240|M.ulcerans_Agy99 IPSSALTVYGRDLGDNATSGPAAINQTLDTP----LRLAHFGGEEGRLRR
Mb3690c|M.bovis_AF2122/97 IPPSALTVYQRDLGDHATSGPAAINQTLDTP----LRLPHFGGEEGRLRR
Rv3666c|M.tuberculosis_H37Rv IPPSALTVYQRDLGDHATSGPAAINQTLDTP----LRLPHFGGEEGRLRR
MAV_0464|M.avium_104 IPPSALPVYRRDLGERVTAGPAAINQSLDTP----LRLPHFGGEEGRLRR
MAB_0426|M.abscessus_ATCC_1997 LPDAAYENAKAEFGSAYLERPRPDITSLGFP----MYDPRYRDVR---VR
MSMEG_4545|M.smegmatis_MC2_155 FPANVIAQYKRTDPDHLHSSASGSAVFISWNNPAEPATPAQAALKDLKVR
.* . : . *
Mflv_2761|M.gilvum_PYR-GCK QAIAYAIDRDAIVQATSYG-TAAANQLAIPEGNPWFTPYDRYREDGEE-G
Mvan_3773|M.vanbaalenii_PYR-1 QAVAYAVDRDAIVQATSYG-TAAVNQLAIPQGNPWFTPYDRYRDDGEQ-G
TH_4152|M.thermoresistible__bu RAIAFGIDREAIVTATGYG-TATANQLAIPPGDFWYTHYDRYRYD-----
MMAR_5154|M.marinum_M LALSAAIDRPQICQQIFNG-TRSAARDFTARSLPGFDPHIPGNEALDF-N
MUL_4240|M.ulcerans_Agy99 LALSAAIDRPQICQQIFNG-TRSAARDFTARSLPGFDPHIPGNEALDF-N
Mb3690c|M.bovis_AF2122/97 LALSAAINRPQICQQIFAG-TRSPARDFTARSLPGFDPNLPGNEVLDY-D
Rv3666c|M.tuberculosis_H37Rv LALSAAINRPQICQQIFAG-TRSPARDFTARSLPGFDPNLPGNEVLDY-D
MAV_0464|M.avium_104 LALSAAINRAQICRQIFAD-TRSPARDFTARSLPGFDPNIAGSDALDF-D
MAB_0426|M.abscessus_ATCC_1997 QAISMAIDREAITQVIFSG-TRTPATSYGSAVVYGYRKGACG-KLCEL-H
MSMEG_4545|M.smegmatis_MC2_155 QAVNYSLNRADVVRGLGGPDSAIPSNEILTSTTLGFNDENPYPTPEDKGD
*: .::* : : . :
Mflv_2761|M.gilvum_PYR-GCK LETARDLLRQANAT----PGDLDMLVTTEYPETVTAAQIVADNLAPLGIT
Mvan_3773|M.vanbaalenii_PYR-1 LETARTLLREAGAQ----PRELDMLVTTEYPETVTAAQIIADNLAPLGIS
TH_4152|M.thermoresistible__bu LDRARALLDEARAAGVDPPRRLDMLVTGDYPQTVTAAQIIADNVAPLGIT
MMAR_5154|M.marinum_M PQRARQLWAQANAIS-PWSGSYAIAYNADSGHQEWVDTVANSIKNVLGIE
MUL_4240|M.ulcerans_Agy99 PQRARQLWAQANAIS-PWSGSYAIAYNADSGHQEWVDAVANSIKNVLGIE
Mb3690c|M.bovis_AF2122/97 PQRARRLWAQADAIS-PWSGRYAIAYNADAGHRDWVDAVANSIKNVLGID
Rv3666c|M.tuberculosis_H37Rv PQRARRLWAQADAIS-PWSGRYAIAYNADAGHRDWVDAVANSIKNVLGID
MAV_0464|M.avium_104 PERARRLWAQADAIS-AWSGSYPIAYNADAGHQDWVDAVANGIKNVLGID
MAB_0426|M.abscessus_ATCC_1997 VDEANKLLDEAHFDR-NKPIELWYSS-SSTGALSWVQAIGNQLQSNLKVP
MSMEG_4545|M.smegmatis_MC2_155 PDKAKALLADSGHKDLTLSAAYRNTPEFEKIATSVQNALARSGITLRLVP
: *. * :: . . : :
Mflv_2761|M.gilvum_PYR-GCK VNIRTVDFATWLDEQ--NSGNFDMLMMGWLGNID------PDDFYYAQHH
Mvan_3773|M.vanbaalenii_PYR-1 VKIRTVDFATWLDEQ--NSGNFDMLMMGWLGNID------PDDFYYAQHH
TH_4152|M.thermoresistible__bu VDIRTVDFATWLDEQ--NNGTFDMLMMGWLGNID------PDDYYYAQHH
MMAR_5154|M.marinum_M AMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFP------SMIEFLAPLY
MUL_4240|M.ulcerans_Agy99 AMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFP------SMIEFLAPLY
Mb3690c|M.bovis_AF2122/97 AVAAPQPTFAGFRTQITNRAIDSAFRAGWQGDYP------SMIGFLAPLF
Rv3666c|M.tuberculosis_H37Rv AVAAPQPTFAGFRTQITNRAIDSAFRAGWRGDYP------SMIEFLAPLF
MAV_0464|M.avium_104 ALGAPQPTFAGFRTQITNRSIGSAFRSGWQGDYP------SMIEFLAPLF
MAB_0426|M.abscessus_ATCC_1997 YLLKSLP-WSQFLPLQDGKGMTGPFRSGWVMDYP------SIYNFLESLY
MSMEG_4545|M.smegmatis_MC2_155 IAGDSWGAFRAYLADKSNLDQWDLAITTWTPDWQGNSARMTLGGWLNSDF
. . * : . : .
Mflv_2761|M.gilvum_PYR-GCK TDG-----TSNAQKFSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADE
Mvan_3773|M.vanbaalenii_PYR-1 TDG-----TSNAQKFSDPEVDRLLDASRVETDEAARKEQYAGAATLIADK
TH_4152|M.thermoresistible__bu TDG-----ASNAQRFSDPEVDRLLDAARAEPDRDRRKALYDRAATLIADR
MMAR_5154|M.marinum_M GTG----AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHD
MUL_4240|M.ulcerans_Agy99 GTG----AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHD
Mb3690c|M.bovis_AF2122/97 TAG----AGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHD
Rv3666c|M.tuberculosis_H37Rv TAG----AGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHD
MAV_0464|M.avium_104 ATG----AGSNDVGYSSPRFDAALATAEAAPDLPQAAALANDAQRILFHD
MAB_0426|M.abscessus_ATCC_1997 GTVALPPNGSNYVFYSNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKD
MSMEG_4545|M.smegmatis_MC2_155 APG----GTWNGVTYHNPQLNAAAARAFAAADP---TADWKEANRIASAD
* : . .: . . * :
Mflv_2761|M.gilvum_PYR-GCK VSYIYLYNPSVIQAWNPALSGYEARRDG-AVRFRSASLDSDGNV-----
Mvan_3773|M.vanbaalenii_PYR-1 VSYIYLYNPSVIQAWNPALSGYEARRDG-AVRFRSATFGADGGA-----
TH_4152|M.thermoresistible__bu VSYLFLYNPAVVQAWSPDLSGYRARRDA-AVRFRDASLNRDGLNRDGPP
MMAR_5154|M.marinum_M MPTIPLWDYIAVVGWSTEVSNVQVTWNG-LPDYENLVKA----------
MUL_4240|M.ulcerans_Agy99 MPTIPLWDYIAVVGWSTEVSNVQVTWNG-LPDYENLVKA----------
Mb3690c|M.bovis_AF2122/97 MPVVPLWDYISVVGWSSQVSNVTVTWNG-LPDYENIVKA----------
Rv3666c|M.tuberculosis_H37Rv MPVVPLWDYISVVGWSSQVSNVTVTWNG-LPDYENIVKA----------
MAV_0464|M.avium_104 MPVVPLWNYISVVGWSGEVSHVTVTWNG-LPDYENIVKA----------
MAB_0426|M.abscessus_ATCC_1997 LPAAPLFYEVNQAVHSKRVRNVKIGIQD-CIEYADVEVVQ---------
MSMEG_4545|M.smegmatis_MC2_155 LAWFPLIERVKTIPTSDRVTNWTWQSLGNNADITNISVNS---------
:. * . : .