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IAGRKCLKIASVAAVAVLGVAACGGGGGSGGSSGAANEGGEVNVTMTSFPDYVDPQLSYTMEGWEVLYNT YVPLLTYKHAKGEEGAEVAPGLAEDMPEVSPDGKTYKLKLRQNMKYADGTPIKASDFTYAIQRLFKADSG GSVFFGVIVGANDYAEGKADTITGIQTNDDTGDITINLTEANGTFDNLLGLPFSAPVPPTTPLDTDATNN PPPGSGPFTITSVDAPHTLVMERNPQFQTVKDAGADEVADAHVDKIIVTQNKSNSAQVTDIEQNKTDFMH DPPDADRLPEVKARFGDRFRLEDSINTYYFWMNTQQAPFNDVRVRQAVNYAIDPEALNRVFGGRLHPTQQ ILPPGMPGYEEFTLYPGPDMDKAKQLIAEANPADRDITVWTDDEPDRKRIGEYYHDVLTQLGFNATLKVI AGDVYWTTIGNQTTPDLDTGFGDWFQDFPHPDDFFRPLINGKSILPTNGNNFSRVAIPELDAKMNELLTQ QLTDETKKGYADLDRAYMEQAVWAPYGNEQLATFLSDRMDFDRSYHHVLFNQDFTSFALK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0643 | - | - | 100% (551) | extracellular solute-binding protein, family protein 5, putative |
| M. smegmatis MC2 155 | MSMEG_4545 | - | 1e-29 | 27.83% (460) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_4354 | - | 3e-25 | 24.09% (494) | dipeptide-binding protein of ABC transport system |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3690c | dppA | 2e-09 | 21.76% (510) | periplasmic dipeptide-binding lipoprotein DppA |
| M. gilvum PYR-GCK | Mflv_2761 | - | 5e-26 | 24.75% (501) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv3666c | dppA | 8e-10 | 21.76% (510) | periplasmic dipeptide-binding lipoprotein DppA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0719 | - | 7e-18 | 24.44% (491) | putative oligopeptide ABC transporter, solute-binding protein |
| M. marinum M | MMAR_5154 | dppA | 7e-10 | 24.10% (502) | periplasmic dipeptide-binding lipoprotein DppA |
| M. avium 104 | MAV_0464 | - | 2e-08 | 26.73% (217) | extracellular solute-binding protein, family protein 5 |
| M. thermoresistible (build 8) | TH_4152 | - | 2e-19 | 22.58% (527) | PUTATIVE extracellular solute-binding protein, family 5 |
| M. ulcerans Agy99 | MUL_4240 | dppA | 1e-09 | 24.10% (502) | periplasmic dipeptide-binding lipoprotein DppA |
| M. vanbaalenii PYR-1 | Mvan_0438 | - | 0.0 | 77.37% (548) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0643|M.smegmatis_MC2_155 --------------------------------------MIAGRKCLKIAS
Mvan_0438|M.vanbaalenii_PYR-1 --------------------------------------MHIFRRALIIAC
Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM
Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM
MMAR_5154|M.marinum_M ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
MAV_0464|M.avium_104 --------------------------------------------------
Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA
TH_4152|M.thermoresistible__bu -------------------------------------------------V
MAB_0719|M.abscessus_ATCC_1997 ---------------------------------------------MVRLR
MSMEG_0643|M.smegmatis_MC2_155 VAAVAVLGVAACGGGGGSGGSSGAANEGGEVNVTMTSFPDYVDPQLSYTM
Mvan_0438|M.vanbaalenii_PYR-1 VASLAAFGVAACGSDDSSGGGGGS---GGDITVNATSFPDYIDPQLSYTV
Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCGGGV-LSPDVVLVNGGEPPNPLIPTGTNDS
Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCGGGV-LSPDVVLVNGGEPPNPLIPTGTNDS
MMAR_5154|M.marinum_M RATLAVVAV-LLAVSPVAACGGGV-LSPDLVLVNGGEPPNPLIPTGTNDS
MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACGGGV-LSPDLVLVNGGEPPNPLIPTGTNDS
MAV_0464|M.avium_104 MAVLATAAAALLVVASLAGCGGGV-LSPDLVVVNGGEPPNPLVPTGTNDS
Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVDLGD-GAGGALIAAIAGEPDQLDPHKTTAY
TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVDLGD-LSG-NLIAAIAGEPDQLDPHKTSAY
MAB_0719|M.abscessus_ATCC_1997 KLAVAASAILVAGCGMGRPPGAID---GEYLTVGTTDRVSTLDPAGAYDN
:.. . : . . : * :
MSMEG_0643|M.smegmatis_MC2_155 EGWEVLYNTYVPLLTYKHAKGEEGAEVAPGLAEDMPEVSPDGKTYKLKLR
Mvan_0438|M.vanbaalenii_PYR-1 EGWEVLWNVYTPLLTYRHARGKEGTEVVPALAEALPDISPDGKTYKLKLR
Mb3690c|M.bovis_AF2122/97 NGGRIIDRLFAGLMSY-----DAVGKPSLEVAQSIESA--DNVNYRITVK
Rv3666c|M.tuberculosis_H37Rv NGGRIIDRLFAGLMSY-----DAVGKPSLEVAQSIESA--DNVNYRITVK
MMAR_5154|M.marinum_M YGGRIIDRLFAGLVSY-----DAKGKPSLEVAQSIDTT--DNVNYRILLK
MUL_4240|M.ulcerans_Agy99 YGGRIIDRLFAGLVSY-----DAKGKPSLEVAQSIDTT--DNVNYRILLK
MAV_0464|M.avium_104 QGGRILDRLFAGLMSY-----DAAGNPAPEVAQSIESG--DNVNYRIVLK
Mflv_2761|M.gilvum_PYR-GCK FSFEVLENVFDTLVEP-----DQDLQMKPALAESWEVSP-DQLTWTFRLR
TH_4152|M.thermoresistible__bu FSFQVLENVFDTLVEP-----DEDLRMRPALAESWQVSA-DQRVWTFRLR
MAB_0719|M.abscessus_ATCC_1997 GSFQVENQVYPFLMNFT----PGTGDLKPDLAAGCGFEN--PTLYRCTLK
. .: . : *: :* : ::
MSMEG_0643|M.smegmatis_MC2_155 QNMKYADGTPIKASDFTYAIQR------LFKADSGGSVFFGVIVGANDYA
Mvan_0438|M.vanbaalenii_PYR-1 PNMKYSDGTPIKASDFTYAIQR------LFKTDSGGSVFYNVIAGATEYA
Mb3690c|M.bovis_AF2122/97 PGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPG
Rv3666c|M.tuberculosis_H37Rv PGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPG
MMAR_5154|M.marinum_M PGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAGEPG
MUL_4240|M.ulcerans_Agy99 PGWGFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAGEPG
MAV_0464|M.avium_104 PGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQSFFSPIDGYDALAA--G
Mflv_2761|M.gilvum_PYR-GCK PGVTFHDGTPLAAEDVVFSYRR--------IIDEQLANSD----------
TH_4152|M.thermoresistible__bu PGVTFHDGSPLTADDVVFSYRR--------IIDEHLTNVD----------
MAB_0719|M.abscessus_ATCC_1997 PGSVFANGHELTSSDVKFSYDR------ERVINDPNGPQS----------
. : :* : : .. : :
MSMEG_0643|M.smegmatis_MC2_155 EGKADTITGIQTNDDTGDITINLTEANGTFDNLLGLPFSAPVPPTTPLDT
Mvan_0438|M.vanbaalenii_PYR-1 DGAADTITGITTDDGTGDITIQLTEPNGTFDNLLGLMFAAPIPQSTPLDA
Mb3690c|M.bovis_AF2122/97 DKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDM
Rv3666c|M.tuberculosis_H37Rv DKSRTTMSGLRVVNDL-EFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDM
MMAR_5154|M.marinum_M EGKPTTMSGLHVVNNR-EFTVRLRAPTIDFMLSLGHSSFYPLPEAAFKDM
MUL_4240|M.ulcerans_Agy99 EGKPTTMSGLHVVNNR-EFTVRLRAPTIDFMLSLGHSSFYPLPEAAFKDM
MAV_0464|M.avium_104 QPQQTTMTGLRVVNDL-EFTVRLKAPTVDFKLRLGHSAFYPLPQAAFRDM
Mflv_2761|M.gilvum_PYR-GCK --KFSSVQAVEAPDPS-TVVIRVDRPTPNMLTNLGGFKGMAIVSRANVES
TH_4152|M.thermoresistible__bu --RLSAVTEVTAVDPL-TVRITVARPTPNLLTNLGGFKGMAIVQRANVET
MAB_0719|M.abscessus_ATCC_1997 --LLANLDRVETPDDL-TVDFRLKLPNDQTFPQVLATNAGPVIDEEVFPP
: : . : . . : .. : .:
MSMEG_0643|M.smegmatis_MC2_155 DATNNPPPGSGPFTITSVDAPHTLVMERNPQFQTVKDAGADEVA-DAHVD
Mvan_0438|M.vanbaalenii_PYR-1 DATNNPPPASGPFMFTTVDAPRTLTMERNPQFQTVKDAGADEVA-DAGVD
Mb3690c|M.bovis_AF2122/97 AAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPRNK
Rv3666c|M.tuberculosis_H37Rv AAFGRNPIGNGPYKLA--DGPAGPAWEHNVRIDLVPNPDYHGNR-KPRNK
MMAR_5154|M.marinum_M AAFGRNPIGNGPYRLD--SGGEEPAWEHNVKIDLVPNPDYRGNR-KPRNK
MUL_4240|M.ulcerans_Agy99 AAFGRNPIGNGPYRLD--SGGEEPAWEHNVKIDLVPNPDYRGNR-KPRNK
MAV_0464|M.avium_104 AAFGRHPIGNGPYQLA--GGPDGPAWEHNVRIDLRPNPDYHGNR-KPRNK
Mflv_2761|M.gilvum_PYR-GCK GRIATHPVGTGPFSFL--GQKSG------DSISLRANPDYWAG--PPGVA
TH_4152|M.thermoresistible__bu GRIATHPVGTGPFEFR--GARSG------DSITLVANDDHWAG--PPRLN
MAB_0719|M.abscessus_ATCC_1997 DRLLDDDAIARAEPFA--GPYTITSHTKNQLIGLRANPKYVGGLGKPQWD
. : . : : .
MSMEG_0643|M.smegmatis_MC2_155 KIIVTQNKSNSAQVTDIEQNKTDFMHDPPDADRLPEVKARFGDRFRLEDS
Mvan_0438|M.vanbaalenii_PYR-1 KITLIENKNQSAQVTDIMQNKVDFMMDPVPSDRLQEVKSRYSDRFRMEDS
Mb3690c|M.bovis_AF2122/97 GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALTVYQRDLGDHATSGPA
Rv3666c|M.tuberculosis_H37Rv GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALTVYQRDLGDHATSGPA
MMAR_5154|M.marinum_M GLRFEFYANLETAYSDLLSGNLDVLDT-IPSSALTVYGRDLGDNATSGPA
MUL_4240|M.ulcerans_Agy99 GLRFEFYANLETAYSDLLSGNLDVLDT-IPSSALTVYGRDLGDNATSGPA
MAV_0464|M.avium_104 GLRFEFYANLDTAYADLLSGNLDVLDT-IPPSALPVYRRDLGERVTAGPA
Mflv_2761|M.gilvum_PYR-GCK GVTFRFIPEPSTALSALQAGEVDWTDS-VPPQRVSQLRDDESLQLTVTPS
TH_4152|M.thermoresistible__bu GVTFRFISEPATALSALQAGEIDWTDA-IPTQRVTQLRNDDSLTLAVTPS
MAB_0719|M.abscessus_ATCC_1997 LIGIKYYTGGENLKIDIENRAIDVAYRSLSPNDIETLRVNPRLSVHEGPG
: . : * .. : .
MSMEG_0643|M.smegmatis_MC2_155 --INTYYFWMNTQQAPFNDVRVR--QAVNYAID-PEALNRVFGGRLHPTQ
Mvan_0438|M.vanbaalenii_PYR-1 --INTYYMFMNTERAPFNDVRVR--QAINYAID-PEALNRIFGGRLHPTQ
Mb3690c|M.bovis_AF2122/97 AINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSPAR
Rv3666c|M.tuberculosis_H37Rv AINQTLDTPLRLPHFGGEEGRLRR-LALSAAINRPQICQQIFAGTRSPAR
MMAR_5154|M.marinum_M AINQTLDTPLRLAHFGGEEGRLRR-LALSAAIDRPQICQQIFNGTRSAAR
MUL_4240|M.ulcerans_Agy99 AINQTLDTPLRLAHFGGEEGRLRR-LALSAAIDRPQICQQIFNGTRSAAR
MAV_0464|M.avium_104 AINQSLDTPLRLPHFGGEEGRLRR-LALSAAINRAQICRQIFADTRSPAR
Mflv_2761|M.gilvum_PYR-GCK --NDYWYLALNQARAPWNDVRVR--QAIAYAIDRDAIVQATSYGTAAANQ
TH_4152|M.thermoresistible__bu --NDYWYLALNHARAPWHDLRVR--RAIAFGIDREAIVTATGYGTATANQ
MAB_0719|M.abscessus_ATCC_1997 GELRYIVFNLKTMPGVTDAQKLAIRRAVASLVDREALSRDVYKGVYTPVY
:. . :: *: :: . .
MSMEG_0643|M.smegmatis_MC2_155 QILPPGMPGYEEFTLYPGP---DMDKAKQLIAEANPADRDITVWTDDEPD
Mvan_0438|M.vanbaalenii_PYR-1 QVLPPGMPGYQEYKLYPGP---DMDKARALIAEANPADRDITVWTDDEPD
Mb3690c|M.bovis_AF2122/97 DFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNA
Rv3666c|M.tuberculosis_H37Rv DFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNA
MMAR_5154|M.marinum_M DFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAYNA
MUL_4240|M.ulcerans_Agy99 DFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAISPWSGSYAIAYNA
MAV_0464|M.avium_104 DFTARSLPGFDPNIAGSDALDFDPERARRLWAQADAISAWSGSYPIAYNA
Mflv_2761|M.gilvum_PYR-GCK LAIPEGNPWFTPYDRYREDGEEGLETARDLLRQANAT-----PGDLDMLV
TH_4152|M.thermoresistible__bu LAIPPGDFWYTHYDRYRYD----LDRARALLDEARAAGVDP-PRRLDMLV
MAB_0719|M.abscessus_ATCC_1997 SVVPESMAGSVESFKALYGVKPNVDLARKFLSEAQVAAPVLINLQYN-PD
. . : *: : :*
MSMEG_0643|M.smegmatis_MC2_155 RKRIGEYYHDVLTQLGFNATLKVIAG---DVYWTTIGNQTTPDLDTGFGD
Mvan_0438|M.vanbaalenii_PYR-1 RKRIGEYYHDLLTQLGFNATLKVIAG---DVYWTTVGNQSTPDVDTGFAD
Mb3690c|M.bovis_AF2122/97 DAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAG
Rv3666c|M.tuberculosis_H37Rv DAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAG
MMAR_5154|M.marinum_M DSGHQEWVDTVANSIKNVLGIEAMGAPQPTFAGLRTQITNRTIDTAFRAG
MUL_4240|M.ulcerans_Agy99 DSGHQEWVDAVANSIKNVLGIEAMGAPQPTFAGLRTQITNRTIDTAFRAG
MAV_0464|M.avium_104 DAGHQDWVDAVANGIKNVLGIDALGAPQPTFAGFRTQITNRSIGSAFRSG
Mflv_2761|M.gilvum_PYR-GCK TTEYPETVTAAQIVADNLAPLGITVNIRTVDFATWLDEQNSGNFDMLMMG
TH_4152|M.thermoresistible__bu TGDYPQTVTAAQIIADNVAPLGITVDIRTVDFATWLDEQNNGTFDMLMMG
MAB_0719|M.abscessus_ATCC_1997 HYGGNSSEEYAAVKGQLEASGLFSVDLQSTEWVAYQERRSSDSYPVYQFG
. . .
MSMEG_0643|M.smegmatis_MC2_155 WFQDFPHPDDFFRPLINGKSILPTNGNNFSRVAIPELDAKMNELLTQQLT
Mvan_0438|M.vanbaalenii_PYR-1 WFQDFPHPDDFFRPLLHGDSILPTNGNNLSRANIAENNAKMDELVTKQIT
Mb3690c|M.bovis_AF2122/97 WQGDYPSMIGFLAPLFT-----AGAGSNDVGYINPEFDAALAAAEAAPTL
Rv3666c|M.tuberculosis_H37Rv WRGDYPSMIEFLAPLFT-----AGAGSNDVGYINPEFDAALAAAEAAPTL
MMAR_5154|M.marinum_M WQGDFPSMIEFLAPLYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTL
MUL_4240|M.ulcerans_Agy99 WQGDFPSMIEFLAPLYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTL
MAV_0464|M.avium_104 WQGDYPSMIEFLAPLFA-----TGAGSNDVGYSSPRFDAALATAEAAPDL
Mflv_2761|M.gilvum_PYR-GCK WLGNIDPDDFYYAQHHT-----DGT-SNAQKFSNPEVDRLLDAGRVETDE
TH_4152|M.thermoresistible__bu WLGNIDPDDYYYAQHHT-----DGA-SNAQRFSDPEVDRLLDAARAEPDR
MAB_0719|M.abscessus_ATCC_1997 WFPDFPDPDNYLTPFFMP------DNMLVNHFQNDTITRLITAEVTEPDS
* : : : .
MSMEG_0643|M.smegmatis_MC2_155 DE-TKKGYADLDRAYME-QAVWAPYGNEQLATFLSDRMDFDRSYHHVLFN
Mvan_0438|M.vanbaalenii_PYR-1 DEGVEQQYADLDRAYME-QAVWAPYGNEQFTTFLSERMDFDKSYHHLLFK
Mb3690c|M.bovis_AF2122/97 TESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWNGLPDY
Rv3666c|M.tuberculosis_H37Rv TESHELVNDAQRILFHD-MPVVPLWDYISVVGWSSQVSNVTVTWNGLPDY
MMAR_5154|M.marinum_M QEADRLANVAQRILFHD-MPTIPLWDYIAVVGWSTEVSNVQVTWNGLPDY
MUL_4240|M.ulcerans_Agy99 QEADRLANVAQRILFHD-MPTIPLWDYIAVVGWSTEVSNVQVTWNGLPDY
MAV_0464|M.avium_104 PQAAALANDAQRILFHD-MPVVPLWNYISVVGWSGEVSHVTVTWNGLPDY
Mflv_2761|M.gilvum_PYR-GCK QTRKAGYARAATLIADE-VSYIYLYNPSVIQAWNPALSGYEARRDGAVRF
TH_4152|M.thermoresistible__bu DRRKALYDRAATLIADR-VSYLFLYNPAVVQAWSPDLSGYRARRDAAVRF
MAB_0719|M.abscessus_ATCC_1997 AKRLRIIGQIQDLMARDYISTLPLLTGKQIAVSVKNVDGIKLGPSFKFQF
. .
MSMEG_0643|M.smegmatis_MC2_155 QDFTSFALK-------
Mvan_0438|M.vanbaalenii_PYR-1 QDFTSFALK-------
Mb3690c|M.bovis_AF2122/97 ENIVKA----------
Rv3666c|M.tuberculosis_H37Rv ENIVKA----------
MMAR_5154|M.marinum_M ENLVKA----------
MUL_4240|M.ulcerans_Agy99 ENLVKA----------
MAV_0464|M.avium_104 ENIVKA----------
Mflv_2761|M.gilvum_PYR-GCK RSASLDSDGNV-----
TH_4152|M.thermoresistible__bu RDASLNRDGLNRDGPP
MAB_0719|M.abscessus_ATCC_1997 TPLKKTGGTA------