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M. thermoresistible (build 8) TH_4152 (-)

annotation: extracellular solute-binding protein, family 5
coordinates: 2386710 - 2388245
length: 512

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4152--100% (512)extracellular solute-binding protein, family 5
M. thermoresistible (build 8)TH_2965-1e-2728.31% (491) PUTATIVE extracellular solute-binding protein, family 5
M. thermoresistible (build 8)TH_0742oppA6e-2224.21% (409) PROBABLE PERIPLASMIC OLIGOPEPTIDE-BINDING LIPOPROTEIN OPPA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1311coppA7e-2124.34% (419) periplasmic oligopeptide-binding lipoprotein OppA
M. gilvum PYR-GCKMflv_2761-0.074.46% (505) extracellular solute-binding protein
M. tuberculosis H37RvRv1280coppA7e-2124.34% (419) periplasmic oligopeptide-binding lipoprotein OppA
M. leprae Br4923MLBr_01121-3e-1722.22% (405) putative extracellular solute-binding dependent transport
M. abscessus ATCC 19977MAB_0426-1e-1822.69% (498) peptide ABC transporter DppA
M. marinum MMMAR_5154dppA2e-1724.86% (527) periplasmic dipeptide-binding lipoprotein DppA
M. avium 104MAV_0464-3e-2025.42% (531) extracellular solute-binding protein, family protein 5
M. smegmatis MC2 155MSMEG_4354-0.075.25% (501) dipeptide-binding protein of ABC transport system
M. ulcerans Agy99MUL_4240dppA1e-1724.42% (520) periplasmic dipeptide-binding lipoprotein DppA
M. vanbaalenii PYR-1Mvan_3773-0.073.16% (503) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1311c|M.bovis_AF2122/97           ------------MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFA
Rv1280c|M.tuberculosis_H37Rv        ------------MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFA
MLBr_01121|M.leprae_Br4923          ------------MIMLSR-------IVAAL--------------------
Mflv_2761|M.gilvum_PYR-GCK          -----------------------------------------MARTAVGAA
Mvan_3773|M.vanbaalenii_PYR-1       ----------------------------------------------MRTV
MSMEG_4354|M.smegmatis_MC2_155      ---------------------------------------------MAGMA
TH_4152|M.thermoresistible__bu      -------------------------------------------------V
MMAR_5154|M.marinum_M               ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99           MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
MAV_0464|M.avium_104                -------------------------------------------------M
MAB_0426|M.abscessus_ATCC_1997      -----------------------------------------------MRL
                                                                                      

Mb1311c|M.bovis_AF2122/97           LLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDG
Rv1280c|M.tuberculosis_H37Rv        LLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDG
MLBr_01121|M.leprae_Br4923          ----LVVGLILTGCSASN---RLVPSAASNAALGKTSDINPQDPATLKDG
Mflv_2761|M.gilvum_PYR-GCK          VLAVCALVLSLTGCNTGE-RVDLGDGAGGALIAAIAGEPDQLDPHKT---
Mvan_3773|M.vanbaalenii_PYR-1       VLATCVFLAALTGCSPGD-RVDLGAGAADALIAAIAGEPDQLDPHKT---
MSMEG_4354|M.smegmatis_MC2_155      TAWLAALVLVFTACSTGE-RVDLGDEASGNLIAAIAGEPDQLDPQKT---
TH_4152|M.thermoresistible__bu      SNLVAVLLIAATGCAPGQ-RVDLGD-LSGNLIAAIAGEPDQLDPHKT---
MMAR_5154|M.marinum_M               RATLAVVAVLLAVSPVAACGGGVLS--PDLVLVNGGEPPNPLIPTGT---
MUL_4240|M.ulcerans_Agy99           RATLAVVAVLLAVSPVAACGGGVLS--PDLVLVNGGEPPNPLIPTGT---
MAV_0464|M.avium_104                AVLATAAAALLVVASLAGCGGGVLS--PDLVVVNGGEPPNPLVPTGT---
MAB_0426|M.abscessus_ATCC_1997      RRLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNT---
                                         .     .    .     :                .   *      

Mb1311c|M.bovis_AF2122/97           GNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDT
Rv1280c|M.tuberculosis_H37Rv        GNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDT
MLBr_01121|M.leprae_Br4923          GNLRLALTDFPANFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDT
Mflv_2761|M.gilvum_PYR-GCK          -TAYFSFEVLENVFDTLVE----PDQDLQMKPALAESWEVSPD-------
Mvan_3773|M.vanbaalenii_PYR-1       -TSYFSFEVLENVFDTLVE----PDGNLQMQPALARAWEVSPD-------
MSMEG_4354|M.smegmatis_MC2_155      -SAYFSFEVLENVFDTLVE----PDENLQMQPALAESWEVSPD-------
TH_4152|M.thermoresistible__bu      -SAYFSFQVLENVFDTLVE----PDEDLRMRPALAESWQVSAD-------
MMAR_5154|M.marinum_M               -NDSYGGRIIDRLFAGLVSYD----AKGKPSLEVAQSIDTTDN-------
MUL_4240|M.ulcerans_Agy99           -NDSYGGRIIDRLFAGLVSYD----AKGKPSLEVAQSIDTTDN-------
MAV_0464|M.avium_104                -NDSQGGRILDRLFAGLMSYD----AAGNPAPEVAQSIESGDN-------
MAB_0426|M.abscessus_ATCC_1997      -TENQGGRILRSLFTALVEFNN--ETAAVEYTGVAESITSHDN-------
                                     .   .   :   *  *                :..:     :       

Mb1311c|M.bovis_AF2122/97           NYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIHA----ISG
Rv1280c|M.tuberculosis_H37Rv        NYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIHA----ISG
MLBr_01121|M.leprae_Br4923          NYFTSIKLTSTSPQVVTYTINPKAVWSDGTPITWRDIDRQIHA----NSG
Mflv_2761|M.gilvum_PYR-GCK          ------------QLTWTFRLRPGVTFHDGTPLAAEDVVFSYRR----IID
Mvan_3773|M.vanbaalenii_PYR-1       ------------QLTWTFHLRPGVTFHDGTPLTADDVVFSYRR----IID
MSMEG_4354|M.smegmatis_MC2_155      ------------QLTWTFHLRDGVRWHDGTPLTADDVVYSYRR----IID
TH_4152|M.thermoresistible__bu      ------------QRVWTFRLRPGVTFHDGSPLTADDVVFSYRR----IID
MMAR_5154|M.marinum_M               -------------VNYRILLKPGWRFTDGSPVTAHSFVDAWNYGALSTNA
MUL_4240|M.ulcerans_Agy99           -------------VNYRILLKPGWGFTDGSPVTAHSFVDAWNYGALSTNA
MAV_0464|M.avium_104                -------------VNYRIVLKPGWRFTDGSPVTAHSFVDAWNYGALSTNA
MAB_0426|M.abscessus_ATCC_1997      -------------VNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNA
                                                       :.    : :* *::  .     .        

Mb1311c|M.bovis_AF2122/97           ADKAFEIASSSGAERVASVTRGVDDR--------------QAVVTFAKPY
Rv1280c|M.tuberculosis_H37Rv        ADKAFEIASSSGAERVASVTRGVDDR--------------QAVVTFAKPY
MLBr_01121|M.leprae_Br4923          KNKAFEIAGTNGCERVASIRPGANDR--------------QAIVTFAQPY
Mflv_2761|M.gilvum_PYR-GCK          EQ----LANSDKFSSVQAVE-APDPS--------------TVVIRVDRPT
Mvan_3773|M.vanbaalenii_PYR-1       EQ----LANSDKFSSVAAVD-APDPN--------------TVVIRVDRPT
MSMEG_4354|M.smegmatis_MC2_155      EQ----LTNVDKFSAVTDVS-APDPA--------------TVRIVVSHPT
TH_4152|M.thermoresistible__bu      EH----LTNVDRLSAVTEVT-AVDPL--------------TVRITVARPT
MMAR_5154|M.marinum_M               QLQQHFFSPIEGYEEVAGEPGEGKP---TTMSGLHVVNNREFTVRLRAPT
MUL_4240|M.ulcerans_Agy99           QLQQHFFSPIEGYEEVAGEPGEGKP---TTMSGLHVVNNREFTVRLRAPT
MAV_0464|M.avium_104                QLQQSFFSPIDGYDALAA--GQPQQ---TTMTGLRVVNDLEFTVRLKAPT
MAB_0426|M.abscessus_ATCC_1997      QGSSSFLANVDGFDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPF
                                          ::  .  . :                           : .  * 

Mb1311c|M.bovis_AF2122/97           AEWRGMFAGNGMLLPASMTATPEAFNKGQLDGPGPSAGPFVVSALD----
Rv1280c|M.tuberculosis_H37Rv        AEWRGMFAGNGMLLPASMTATPEAFNKGQLDGPGPSAGPFVVSALD----
MLBr_01121|M.leprae_Br4923          AEWRGMFAGNGMLLPATMTATPEAFNKGQLDRPGPSAGPFIVSSLD----
Mflv_2761|M.gilvum_PYR-GCK          PNMLTNLGG----FKGMAIVSRANVESGRIATHPVGTGPFSFLGQ-----
Mvan_3773|M.vanbaalenii_PYR-1       PNMLTNLGG----FKGMAIVSRANVESGRIATQPVGTGPFRFLGQ-----
MSMEG_4354|M.smegmatis_MC2_155      PNLLTNLGG----FKGMAIVQRGNVESGQIATHPIGTGPFAFAGR-----
TH_4152|M.thermoresistible__bu      PNLLTNLGG----FKGMAIVQRANVETGRIATHPVGTGPFEFRGA-----
MMAR_5154|M.marinum_M               IDFMLSLGHS----SFYPLPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPA
MUL_4240|M.ulcerans_Agy99           IDFMLSLGHS----SFYPLPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPA
MAV_0464|M.avium_104                VDFKLRLGHS----AFYPLPQAAFRDMAAFGRHPIGNGPYQLAGGPDGPA
MAB_0426|M.abscessus_ATCC_1997      AIYPMTLGYT----AFLPLPKAFFRDPVKFGVHPIGNGPFKADG-----D
                                          :.                 :   :     . **:   .      

Mb1311c|M.bovis_AF2122/97           -RTAQRIVLTRNPRWWGA-RPRLDSITY-LVLDDAARLPALQNNTIDATG
Rv1280c|M.tuberculosis_H37Rv        -RTAQRIVLTRNPRWWGA-RPRLDSITY-LVLDDAARLPALQNNTIDATG
MLBr_01121|M.leprae_Br4923          -RTTQRIVLTHNPKWWGT-PPRLDSITY-LVLDDAARLPALQNNTIDATG
Mflv_2761|M.gilvum_PYR-GCK          -KSGDSISLRANPDYWAG-PPGVAGVTFRFIPEPSTALSALQAGEVDWTD
Mvan_3773|M.vanbaalenii_PYR-1       -KSGDSISLAANPNYWDG-PPGVSGVTYRFISEPSTALSALQAGEIDWTD
MSMEG_4354|M.smegmatis_MC2_155      -KSGDSITLKANPHYWGP-EPRVSGVTFRFISEPATALSALQAGEIDWTD
TH_4152|M.thermoresistible__bu      -RSGDSITLVANDDHWAG-PPRLNGVTFRFISEPATALSALQAGEIDWTD
MMAR_5154|M.marinum_M               WEHNVKIDLVPNPDYRGNRKPRNKGLRFEFYANLETAYSDLLSGNLDVLD
MUL_4240|M.ulcerans_Agy99           WEHNVKIDLVPNPDYRGNRKPRNKGLRFEFYANLETAYSDLLSGNLDVLD
MAV_0464|M.avium_104                WEHNVRIDLRPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLD
MAB_0426|M.abscessus_ATCC_1997      WVRGVGFTLSRYDQYAGEKKAKAKGLIWRVYTEGLTAYTDMQAGALDIQL
                                          : *           .   .: : .  :  :  . :  . :*   

Mb1311c|M.bovis_AF2122/97           VGTLDQLTIAARTKGISIRRAPGP--SWYHFTLNGAPGSILADKALRLAI
Rv1280c|M.tuberculosis_H37Rv        VGTLDQLTIAARTKGISIRRAPGP--SWYHFTLNGAPGSILADKALRLAI
MLBr_01121|M.leprae_Br4923          VGTLDQLTTAQRTNGISIRRTPAP--RWSHFTFNGAVGSILADQGLRLAV
Mflv_2761|M.gilvum_PYR-GCK          SVPPQRVSQLRDDESLQLTVTPSN--DYWYLALNQAR-APWNDVRVRQAI
Mvan_3773|M.vanbaalenii_PYR-1       SVPPQRVTQLRDDESLELAVTPSN--DYWYLALNEAR-EPWNDVRVRQAV
MSMEG_4354|M.smegmatis_MC2_155      SVPPQRVAQLRDDDSLTLAVTPSN--DYWYLALNEAR-APWNDVRVRQAI
TH_4152|M.thermoresistible__bu      AIPTQRVTQLRNDDSLTLAVTPSN--DYWYLALNHAR-APWHDLRVRRAI
MMAR_5154|M.marinum_M               TIPSSALTVYGRDLGDNATSGPAAINQTLDTPLRLAHFGGEEGRLRRLAL
MUL_4240|M.ulcerans_Agy99           TIPSSALTVYGRDLGDNATSGPAAINQTLDTPLRLAHFGGEEGRLRRLAL
MAV_0464|M.avium_104                TIPPSALPVYRRDLGERVTAGPAAINQSLDTPLRLPHFGGEEGRLRRLAL
MAB_0426|M.abscessus_ATCC_1997      DLPDAAYENAKAEFGSAYLERPRPDITSLGFPMYDPRYRDVR---VRQAI
                                      .           .      *         .:  .          * *:

Mb1311c|M.bovis_AF2122/97           AKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQA
Rv1280c|M.tuberculosis_H37Rv        AKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQA
MLBr_01121|M.leprae_Br4923          SKGIDRRTIAKVVQYGLANNPEPLNNHVYVDGQEGYQDNSGVVGYDPEQA
Mflv_2761|M.gilvum_PYR-GCK          AYAIDRDAIVQATSYGTAA----ANQLAIPEGNPWFTPYDRYREDGEEGL
Mvan_3773|M.vanbaalenii_PYR-1       AYAVDRDAIVQATSYGTAA----VNQLAIPQGNPWFTPYDRYRDDGEQGL
MSMEG_4354|M.smegmatis_MC2_155      AYGIDRDAIATATSYRTAA----INQLAIPEGNPWFTSYDRYRFD----L
TH_4152|M.thermoresistible__bu      AFGIDREAIVTATGYGTAT----ANQLAIPPGDFWYTHYDRYRYD----L
MMAR_5154|M.marinum_M               SAAIDRPQICQQIFNGTRSAARDFTARSLPGFDPHIPGNEALDFN----P
MUL_4240|M.ulcerans_Agy99           SAAIDRPQICQQIFNGTRSAARDFTARSLPGFDPHIPGNEALDFN----P
MAV_0464|M.avium_104                SAAINRAQICRQIFADTRSPARDFTARSLPGFDPNIAGSDALDFD----P
MAB_0426|M.abscessus_ATCC_1997      SMAIDREAITQVIFSGTRTPATSYGSAVVYGYRKGACG-KLCELH----V
                                    : .::*  *                              .          

Mb1311c|M.bovis_AF2122/97           KRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIG
Rv1280c|M.tuberculosis_H37Rv        KRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIG
MLBr_01121|M.leprae_Br4923          QHELDALGWKLNGQFREKDGRQLVIRYLFYDAQGSREFAQLAQHSLAQIG
Mflv_2761|M.gilvum_PYR-GCK          ETARDLLRQANAT----PGDLDMLVTTEYPETVT---AAQIVADNLAPLG
Mvan_3773|M.vanbaalenii_PYR-1       ETARTLLREAGAQ----PRELDMLVTTEYPETVT---AAQIIADNLAPLG
MSMEG_4354|M.smegmatis_MC2_155      DESKRLLDEAGAH----PENLDMLVTSEYPETVT---AAQIIADNLAPLG
TH_4152|M.thermoresistible__bu      DRARALLDEARAAGVDPPRRLDMLVTGDYPQTVT---AAQIIADNVAPLG
MMAR_5154|M.marinum_M               QRARQLWAQANAI----SPWSGSYAIAYNADSGHQEWVDTVANSIKNVLG
MUL_4240|M.ulcerans_Agy99           QRARQLWAQANAI----SPWSGSYAIAYNADSGHQEWVDAVANSIKNVLG
MAV_0464|M.avium_104                ERARRLWAQADAI----SAWSGSYPIAYNADAGHQDWVDAVANGIKNVLG
MAB_0426|M.abscessus_ATCC_1997      DEANKLLDEAHFD----RNKPIELWYSS-SSTGALSWVQAIGNQLQSNLK
                                    .                             .:        :       : 

Mb1311c|M.bovis_AF2122/97           VKLELQAKS-GSGFFSDYVNVGAFDIAQFGWVGDAFPLSSLTQIYASDG-
Rv1280c|M.tuberculosis_H37Rv        VKLELQAKS-GSGFFSDYVNVGAFDIAQFGWVGDAFPLSSLTQIYASDG-
MLBr_01121|M.leprae_Br4923          VKLELQAKA-GSGFFTNYVNVGAFDIVQFGWVGDAFPLSALTQIYQSDG-
Mflv_2761|M.gilvum_PYR-GCK          ITVNIRTVD-FATWLDE-QNSGNFDMLMMGWLGNIDPDDFYYAQHHTDG-
Mvan_3773|M.vanbaalenii_PYR-1       ISVKIRTVD-FATWLDE-QNSGNFDMLMMGWLGNIDPDDFYYAQHHTDG-
MSMEG_4354|M.smegmatis_MC2_155      ISVNIRTVD-FATWLDE-QNTGNFDMLMMGWLGNIDPDDFYYAQHHSNG-
TH_4152|M.thermoresistible__bu      ITVDIRTVD-FATWLDE-QNNGTFDMLMMGWLGNIDPDDYYYAQHHTDG-
MMAR_5154|M.marinum_M               IEAMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFPSMIEFLAPLYGTG-
MUL_4240|M.ulcerans_Agy99           IEAMGAPQPTFAGLRTQITNRTIDTAFRAGWQGDFPSMIEFLAPLYGTG-
MAV_0464|M.avium_104                IDALGAPQPTFAGFRTQITNRSIGSAFRSGWQGDYPSMIEFLAPLFATG-
MAB_0426|M.abscessus_ATCC_1997      VPYLLKSLP-WSQFLPLQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVA
                                    :     .    :       .         **  :  .             

Mb1311c|M.bovis_AF2122/97           ----ESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSL
Rv1280c|M.tuberculosis_H37Rv        ----ESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSL
MLBr_01121|M.leprae_Br4923          ----ESNFGKISSPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSL
Mflv_2761|M.gilvum_PYR-GCK          ----TSNAQKFSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYI
Mvan_3773|M.vanbaalenii_PYR-1       ----TSNAQKFSDPEVDRLLDASRVETDEAARKEQYAGAATLIADKVSYI
MSMEG_4354|M.smegmatis_MC2_155      ----TSNAQKFSDPEVDRLLDAGRVETDTAERKDVYARAATRIADEVSYI
TH_4152|M.thermoresistible__bu      ----ASNAQRFSDPEVDRLLDAARAEPDRDRRKALYDRAATLIADRVSYL
MMAR_5154|M.marinum_M               ---AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHDMPTI
MUL_4240|M.ulcerans_Agy99           ---AGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRILFHDMPTI
MAV_0464|M.avium_104                ---AGSNDVGYSSPRFDAALATAEAAPDLPQAAALANDAQRILFHDMPVV
MAB_0426|M.abscessus_ATCC_1997      LPPNGSNYVFYSNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAA
                                         **    ..  .*  :                  .   :       

Mb1311c|M.bovis_AF2122/97           PLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR--------
Rv1280c|M.tuberculosis_H37Rv        PLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR--------
MLBr_01121|M.leprae_Br4923          PLTQSPGDVAVRSTLANFGAAGFGDLNYTAIGFMQN--------
Mflv_2761|M.gilvum_PYR-GCK          YLYNPSVIQAWNPALSGYEARRDGAVRFRSASLDSDGNV-----
Mvan_3773|M.vanbaalenii_PYR-1       YLYNPSVIQAWNPALSGYEARRDGAVRFRSATFGADGGA-----
MSMEG_4354|M.smegmatis_MC2_155      YLYNPSVIQAWSNDLSGYVARRDGAIRFRTADLGRGGPE-----
TH_4152|M.thermoresistible__bu      FLYNPAVVQAWSPDLSGYRARRDAAVRFRDASLNRDGLNRDGPP
MMAR_5154|M.marinum_M               PLWDYIAVVGWSTEVSNVQVTWNGLPDYENLVKA----------
MUL_4240|M.ulcerans_Agy99           PLWDYIAVVGWSTEVSNVQVTWNGLPDYENLVKA----------
MAV_0464|M.avium_104                PLWNYISVVGWSGEVSHVTVTWNGLPDYENIVKA----------
MAB_0426|M.abscessus_ATCC_1997      PLFYEVNQAVHSKRVRNVKIGIQDCIEYADVEVVQ---------
                                     *            :            :