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VVDQLDTGQLAALSAVVEFGSFDAAAERLHVTPSAISQRIKALEQRVGQVLVLREKPCVATPAGVPLLRL AAQTALLQAEALAEMRGGSAELPRIAMAVNADSMATWFTEVFARLPHVLFDIRIEDQDHSAQLLREGVVM GAVTTERAPVAGCRVQPLGVMRYVPVATEAYVQRHLPDGFTREAAERAPSLAWNRADALQDQLVRKVFRR SVARPVHYVPTAAGFGAAVHAGLGWGMYPIQLLDASFVPITDQHLDVPLYWQCWKLDSDTVRQVTAAVDS AASGLLRDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0375 | - | - | 100% (289) | chromosome replication initiation inhibitor protein |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 3e-07 | 31.03% (174) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 4e-05 | 26.67% (135) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2007c | - | 1e-112 | 71.13% (291) | chromosome replication initiation inhibitor protein |
| M. gilvum PYR-GCK | Mflv_0362 | - | 1e-143 | 86.51% (289) | chromosome replication initiation inhibitor protein |
| M. tuberculosis H37Rv | Rv1985c | - | 1e-112 | 71.13% (291) | chromosome replication initiation inhibitor protein |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-08 | 27.13% (258) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4381c | - | 5e-86 | 58.42% (291) | chromosome replication initiation inhibitor protein |
| M. marinum M | MMAR_3419 | - | 5e-08 | 24.29% (247) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2838 | - | 1e-07 | 28.95% (190) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_0548 | - | 1e-124 | 77.27% (286) | chromosome replication initiation inhibitor protein |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-05 | 33.33% (81) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-07 | 24.79% (238) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2007c|M.bovis_AF2122/97 --MVDPQLDGPQLAALAAVVELGSFDAAAERLHVTPSAVSQRIKSLEQQV
Rv1985c|M.tuberculosis_H37Rv --MVDPQLDGPQLAALAAVVELGSFDAAAERLHVTPSAVSQRIKSLEQQV
Mvan_0375|M.vanbaalenii_PYR-1 ---MVDQLDTGQLAALSAVVEFGSFDAAAERLHVTPSAISQRIKALEQRV
Mflv_0362|M.gilvum_PYR-GCK ---MTDHLDTAHLAALSAVVEFGSFDAAGAHLHITPSAVSQRIKALEQRV
MSMEG_0548|M.smegmatis_MC2_155 -----MQIDGQQLAAFAAVIELGSFDAAAARLHVTPSAVSQRIKALEQRV
MAB_4381c|M.abscessus_ATCC_199 -----MSLDSQQLVAFAAVVDEGSFDAAARRLMITPSAVSQRVKALERSV
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
MAV_2838|M.avium_104 MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGL
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
: : *: : : *. * : .::*. : ::*
Mb2007c|M.bovis_AF2122/97 GQVLVVR-EKPCRATTAGIPLLRLAAQTALLESEALAEMGGNASLKRTRI
Rv1985c|M.tuberculosis_H37Rv GQVLVVR-EKPCRATTAGIPLLRLAAQTALLESEALAEMGGNASLKRTRI
Mvan_0375|M.vanbaalenii_PYR-1 GQVLVLR-EKPCVATPAGVPLLRLAAQTALLQAEALAEMRG-GSAELPRI
Mflv_0362|M.gilvum_PYR-GCK GQVLVLR-EKPCVATPAGAPLLRLAAQTALLQAEALAELRG-GTADLPRI
MSMEG_0548|M.smegmatis_MC2_155 GQVLVVR-EKPCTATPAGVPLLRLAAQTALLESEALAEMGG-GSSHRPRM
MAB_4381c|M.abscessus_ATCC_199 GQVLVRR-EKPCVATDAGTSLMRLAAQIGTLEREALQEMGG---GVPIRV
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
MAV_2838|M.avium_104 GTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGM
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
* * * : * * : .
Mb2007c|M.bovis_AF2122/97 TIAVN----ADSMATWFSAVFDGLGD-----VLLDVRIEDQDHSARLLRE
Rv1985c|M.tuberculosis_H37Rv TIAVN----ADSMATWFSAVFDGLGD-----VLLDVRIEDQDHSARLLRE
Mvan_0375|M.vanbaalenii_PYR-1 AMAVN----ADSMATWFTEVFARLPH-----VLFDIRIEDQDHSAQLLRE
Mflv_0362|M.gilvum_PYR-GCK ALAVN----ADSMATWFTEVLTRLPH-----VLFDVRIEDQDHSARLLRE
MSMEG_0548|M.smegmatis_MC2_155 ALAVN----ADSMASWFTGVFRRLPD-----VLFDIRIEDQDLSARFLRE
MAB_4381c|M.abscessus_ATCC_199 AIAVN----ADSFGTWMGSVVSQIPDG----VLIDIRIEDQDHSAELLRA
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRL-----PTLTLRVVEDQTEHLLTALRE
MAV_2838|M.avium_104 RLGLIPTVAPYVLPTVLAGIAERR-----PGLTLRVTEDQTERLLAVLRE
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYPS-----TSFTLRQLYPDALTDAVFD
:. : . : : :
Mb2007c|M.bovis_AF2122/97 GVAMGAVTTERNPVPGCRVHPLGEMRYLPVASRPFVQRHLSDGFTA---A
Rv1985c|M.tuberculosis_H37Rv GVAMGAVTTERNPVPGCRVHPLGEMRYLPVASRPFVQRHLSDGFTA---A
Mvan_0375|M.vanbaalenii_PYR-1 GVVMGAVTTERAPVAGCRVQPLGVMRYVPVATEAYVQRHLPDGFTR---E
Mflv_0362|M.gilvum_PYR-GCK GVVMGAVTTERAPVAGCRVHALGVMRYVPVASRDYVARHFPDGFTR---E
MSMEG_0548|M.smegmatis_MC2_155 GVVMGAVTTERTPVSGCRVHPLGAMRYIPVASAEYMARYLPDGFNR---E
MAB_4381c|M.abscessus_ATCC_199 GVVMAAVTTEPRPIAGCRSESLGAMRYFGMASPEYVERHLPDGLLDSGID
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRR-VPTT---
MAV_2838|M.avium_104 GALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRR-VPAT---
MMAR_3419|M.marinum_M GTADLGFVENPGPPTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTAR---
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGPPTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTAR---
TH_3504|M.thermoresistible__bu GTVQLGLRRGVVPTPELATAVIGYHRVRVAFVDSHPLAARESVDITEL--
*. .. . : .
Mb2007c|M.bovis_AF2122/97 AAAKAPSLAWNRDDGLQDMLVRKAFRRAITRPTHFVP------TTEGFTA
Rv1985c|M.tuberculosis_H37Rv AAAKAPSLAWNRDDGLQDMLVRKAFRRAITRPTHFVP------TTEGFTA
Mvan_0375|M.vanbaalenii_PYR-1 AAERAPSLAWNRADALQDQLVRKVFRRSVARPVHYVP------TAAGFGA
Mflv_0362|M.gilvum_PYR-GCK AASKAPSLAWNRDDALQDQLVRKVFRRSVQRPTHYVP------TATGFGA
MSMEG_0548|M.smegmatis_MC2_155 AAAAAPSLAWNRDDRLQDQLVRKVFRRDVTRPVHFIP------TAEGFGA
MAB_4381c|M.abscessus_ATCC_199 KVRQAPLIRWDRRDALQDQFLRKLFRRDVVVAGHCVP------TTVGFTA
MLBr_02041|M.leprae_Br4923 ALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTR----AASLATAVQ
MAV_2838|M.avium_104 ALADLPLLLLDEGHCLRDQALDVCHKAGVRAELANTR----AASLATAVQ
MMAR_3419|M.marinum_M ELAETPLVTREPRSGIRDS-LTVALRQVLGEDMVQASPVLELSSAAAMRA
MUL_2698|M.ulcerans_Agy99 ELAEMPLVTREPRSGIRDS-LTVALRQVLGEDMVQASPVLELSSAAAMRA
TH_3504|M.thermoresistible__bu AREQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSR-----VQGAATVA
. * : : .
Mb2007c|M.bovis_AF2122/97 AARAGLGWGMFPEKLAASPLADGSFVRVC----DIHLDVPLYWQCWKLDS
Rv1985c|M.tuberculosis_H37Rv AARAGLGWGMFPEKLAASPLADGSFVRVC----DIHLDVPLYWQCWKLDS
Mvan_0375|M.vanbaalenii_PYR-1 AVHAGLGWGMYPIQ-----LLDASFVPIT----DQHLDVPLYWQCWKLDS
Mflv_0362|M.gilvum_PYR-GCK AVHAGLGWGMYPIA-----LLDGSFVPIT----EQHLDVPLYWQCWKLDS
MSMEG_0548|M.smegmatis_MC2_155 AVRAGLGWGMYPED-----LVDASFVPIT----EHHLDVPLFWQCWKLDS
MAB_4381c|M.abscessus_ATCC_199 ALRAGLGWGMMPEQ-----LGREGLVELAP---GRYLDVPLYWQHWKFES
MLBr_02041|M.leprae_Br4923 CVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRS
MAV_2838|M.avium_104 CVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRD
MMAR_3419|M.marinum_M AVLAGAGPAAMSRLAIADDLAVGRLRAISIPGLDLRRQLRAIWVG--GRV
MUL_2698|M.ulcerans_Agy99 AVLAGAGPAAMSRLAIADDLAVGRLRAISIPGLDLRRQLRAIWVG--GRV
TH_3504|M.thermoresistible__bu APLTTGGIAFVTAAAGPTMNGRVQVVDLTP---PLLVPVQALWQR-----
. * . . : :
Mb2007c|M.bovis_AF2122/97 PIIARITDTVRAAASGLYRGQQRRRRPG
Rv1985c|M.tuberculosis_H37Rv PIIARITDTVRAAASGLYRGQQRRRRPG
Mvan_0375|M.vanbaalenii_PYR-1 DTVRQVTAAVDSAASGLLRDR-------
Mflv_0362|M.gilvum_PYR-GCK AVVAQVTAAVDAAAAGLLRDR-------
MSMEG_0548|M.smegmatis_MC2_155 PLVQAITDAVLAASARLRGRRTAAER--
MAB_4381c|M.abscessus_ATCC_199 STLSAITSAVREAATVLRRSR-------
MLBr_02041|M.leprae_Br4923 ASYRQIAKIIGELISTEHHVRLVA----
MAV_2838|M.avium_104 DSYRELAGLIGELISSQHQVRLVK----
MMAR_3419|M.marinum_M PPAGAIRELLSHITSGGE----------
MUL_2698|M.ulcerans_Agy99 PPAGAIRELLSHITSGGE----------
TH_3504|M.thermoresistible__bu HTLSAIRDRILEGLG-------------
: :