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MRRQQHRRRQMAAQSTDEVGARILDAALELLRARGPRAVTMQAIVDATGIAKTTIYRRHQNRRMLLTAAL ETLGERPSAPPESGRAERLQWVITQSVDVIAAGIGAGGFAALLTDEDPEFSEAFRAILVAYRRQAIDALA IGDRVGDTLVDIIVGSYVAELARTGSIDDGWAARIAAVLDGVLDAAAND
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0230 | - | - | 100% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 3e-08 | 30.92% (152) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0323 | - | 1e-07 | 30.50% (141) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1998c | - | 7e-05 | 26.19% (126) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0437 | - | 3e-71 | 77.46% (173) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-05 | 37.93% (58) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00949 | - | 7e-05 | 33.71% (89) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_3565 | - | 4e-07 | 33.77% (151) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4834 | - | 4e-08 | 42.86% (63) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3805 | - | 1e-08 | 37.80% (82) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0986 | - | 4e-39 | 44.95% (198) | RemM protein |
| M. thermoresistible (build 8) | TH_1099 | - | 4e-34 | 43.10% (174) | RemM protein |
| M. ulcerans Agy99 | MUL_1299 | - | 8e-05 | 32.76% (58) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0230|M.vanbaalenii_PYR-1 ----MRRQQHRRRQMAAQSTDEVGARILDAALELLRARGPRAVTMQAIVD
Mflv_0437|M.gilvum_PYR-GCK --------------MAANSGDDVGARILDAALELLRARGPKAVTMQAVVD
MSMEG_0986|M.smegmatis_MC2_155 --------------MADRR--RVEDGIAESTLHLLRSGGPRAVTVEAVTS
TH_1099|M.thermoresistible__bu --------------MAVR---DVDDGIADATLALLRTKGPRSATVQAVAA
MMAR_4834|M.marinum_M MERDTLEFPVDDDDDVDPRRLRSRTRLLDAATKLLSAGGIEAVTIDAVTK
MAV_3805|M.avium_104 MGTQPAETP-DDEDDVDPRRTRSRTRLLDAAANLLKTGGIEAVTIDAVTK
MAB_3565|M.abscessus_ATCC_1997 ----MANRQTVQGVRTGGRSARVREAILDAAFGELIDRGYAELTMEAVAS
Mb1998c|M.bovis_AF2122/97 --------MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAE
Rv1255c|M.tuberculosis_H37Rv --------MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAK
MLBr_00949|M.leprae_Br4923 -------MTTSARTHRWAKTGAIQRRILDAAIEVFATRSFTTATMTDAMT
MUL_1299|M.ulcerans_Agy99 ------------MLSMSNAPEDIGDRILQAAASCVRDYGVDRVTLAEIAR
: : : . . :
Mvan_0230|M.vanbaalenii_PYR-1 ATGIAKTTIYRRHQNRRMLLTAALET------------------------
Mflv_0437|M.gilvum_PYR-GCK ATGIAKTTIYRRHPNRRTLLAAALET------------------------
MSMEG_0986|M.smegmatis_MC2_155 HSGIAKTTIYRRHHNRREMLAAALSG------------------------
TH_1099|M.thermoresistible__bu QSGIAKTTIYRRFRDRRDMLSAALSR------------------------
MMAR_4834|M.marinum_M ASKVARTTLYRHFSSSTQLLAATFER------------------------
MAV_3805|M.avium_104 ASKVARTTLYRHFNSSSQLLAATFER------------------------
MAB_3565|M.abscessus_ATCC_1997 RAGVNKTTIYRRWPTLEDLLVEALTT------------------------
Mb1998c|M.bovis_AF2122/97 AAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRLTEGETEPTPRPLN
Rv1255c|M.tuberculosis_H37Rv AAGCSRATLYRYFDSREALRTAYVHRETRR--------------------
MLBr_00949|M.leprae_Br4923 GSGAIIGSIYHHFGGKRKLFLAIFEQ------------------------
MUL_1299|M.ulcerans_Agy99 RAGVSRPTVYRRWPDTRSIISALLTS------------------------
: ::*: : .
Mvan_0230|M.vanbaalenii_PYR-1 ---------------------------------------------LGERP
Mflv_0437|M.gilvum_PYR-GCK ---------------------------------------------LGERP
MSMEG_0986|M.smegmatis_MC2_155 ---------------------------------------------LATPE
TH_1099|M.thermoresistible__bu ---------------------------------------------VAHPD
MMAR_4834|M.marinum_M ---------------------------------------------LLPQV
MAV_3805|M.avium_104 ---------------------------------------------LLPQV
MAB_3565|M.abscessus_ATCC_1997 ---------------------------------------------WSLEA
Mb1998c|M.bovis_AF2122/97 ADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMRDSV
Rv1255c|M.tuberculosis_H37Rv ---------------------------------------------LGREI
MLBr_00949|M.leprae_Br4923 ---------------------------------------------MGRQR
MUL_1299|M.ulcerans_Agy99 ---------------------------------------------HVTDV
Mvan_0230|M.vanbaalenii_PYR-1 SAPP----------------------------------------------
Mflv_0437|M.gilvum_PYR-GCK SVPA----------------------------------------------
MSMEG_0986|M.smegmatis_MC2_155 SLDPGAESTLHLLRSGGPRAVTVEAVTSHSGIAKTTIYRRHHNRREMLAA
TH_1099|M.thermoresistible__bu PLEP----------------------------------------------
MMAR_4834|M.marinum_M HPP-----------------------------------------------
MAV_3805|M.avium_104 IPPA----------------------------------------------
MAB_3565|M.abscessus_ATCC_1997 IPIP----------------------------------------------
Mb1998c|M.bovis_AF2122/97 LLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAA
Rv1255c|M.tuberculosis_H37Rv MVKIA---------------------------------------------
MLBr_00949|M.leprae_Br4923 RPPHR---------------------------------------------
MUL_1299|M.ulcerans_Agy99 VRAVF---------------------------------------------
Mvan_0230|M.vanbaalenii_PYR-1 -------------ESGRAERLQWVITQSVDVIAAG---IGAGGFAALLTD
Mflv_0437|M.gilvum_PYR-GCK -------------DATRHERLNWVITQSVDVIAHG---IGAGGFAALLTD
MSMEG_0986|M.smegmatis_MC2_155 ALSGLATPESLDPGADAPDRLRWVIAQAIGTIEDG---IGIGGLAALCTE
TH_1099|M.thermoresistible__bu -------------DTAAPDRLRWLIAQAVKTIEVG---IGYGGFAAMLTD
MMAR_4834|M.marinum_M -----------PATGSMRDQLIELLSRQATLFQEAPLHVTTLAWVALGPT
MAV_3805|M.avium_104 -----------PTSGTLRERLIELLSRQADLFAEAPVQVTTLAWAALGPA
MAB_3565|M.abscessus_ATCC_1997 ------------ETGSIESDLLSTGRELAAVLNDG---VGRQVAALVLTA
Mb1998c|M.bovis_AF2122/97 RTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTS
Rv1255c|M.tuberculosis_H37Rv ------------DVVEPAERLLVSITTTLRMVRDN------PALAAWFTT
MLBr_00949|M.leprae_Br4923 ------------RGDATSGPIRPSGDRSAAGIRSPRTGPTSRRCG-----
MUL_1299|M.ulcerans_Agy99 ------------LDGHDRQTVVRQVVAVADRLRGD------ELVKALMHS
.
Mvan_0230|M.vanbaalenii_PYR-1 -------------------EDPEFSEAFRA--------ILVAYRRQAIDA
Mflv_0437|M.gilvum_PYR-GCK -------------------DDPEFSDAFRA--------ILGAYRRHAIDA
MSMEG_0986|M.smegmatis_MC2_155 -------------------DDPEFNTLFRR--------ILVEQRAALAEV
TH_1099|M.thermoresistible__bu -------------------EDPDFTAVFRE--------ILAGQRAELEAV
MMAR_4834|M.marinum_M -------------------PDGTQETQDRH---ALRARIIDQYRQPFVAL
MAV_3805|M.avium_104 -------------------ETHEPNTVQHAGAGTLRMRVIEQYRRPFDEI
MAB_3565|M.abscessus_ATCC_1997 GL-----------------RSAPLREATRR--------YFDHQVLRAAPV
Mb1998c|M.bovis_AF2122/97 EIGKGAGIAGPGLYRSFSSKQAILDALIRR---LDEWRCLECIRALRANQ
Rv1255c|M.tuberculosis_H37Rv -------------------TRPPIGGEMAG-----RSEVIAALAAAFLNS
MLBr_00949|M.leprae_Br4923 -------------------KTGTRPGCCRP----------ETHLQASRSP
MUL_1299|M.ulcerans_Agy99 -------------------DLARVYITERLG---------ASQHFLLEGL
Mvan_0230|M.vanbaalenii_PYR-1 LAIGDRVG--------DTLVDIIVGSYVAELARTG-SIDDGWAAR-----
Mflv_0437|M.gilvum_PYR-GCK LDVDVATG--------ETVIDLIVGGYVAELARTG-SVDDGWNAR-----
MSMEG_0986|M.smegmatis_MC2_155 IDAAKTDGSMRDDVDAQTLIDAVVGAYIAESARTG-AVADGWQER-----
TH_1099|M.thermoresistible__bu IDGGKADGSIRADVDGSALIDAVVGTHIAERARVG-EVAADWENR-----
MMAR_4834|M.marinum_M LQSPEARADLDDFDMELILCQLIGPVAFARLTGLR-AIDRQDCER-----
MAV_3805|M.avium_104 LYSPESVDQLGELDIELALCQLVGPLVFARMTGLR-VITHQDCTR-----
MAB_3565|M.abscessus_ATCC_1997 VRQAIDRGELPADCDVDMLLTTFRAPLFYRTITTGDPIDDALIIH-----
Mb1998c|M.bovis_AF2122/97 QAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDRE
Rv1255c|M.tuberculosis_H37Rv LGPDDPTTVERRARWVVRMLTSLLMFPGRDEADER-AMIAEFVVP-----
MLBr_00949|M.leprae_Br4923 VATA----------------------------------------------
MUL_1299|M.ulcerans_Agy99 AARLQVAQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDS-----
Mvan_0230|M.vanbaalenii_PYR-1 -----IAAVLDGVLDAAAND------------------------------
Mflv_0437|M.gilvum_PYR-GCK -----MADAVERVLPSR---------------------------------
MSMEG_0986|M.smegmatis_MC2_155 -----LFALFWPIVRASA--------------------------------
TH_1099|M.thermoresistible__bu -----LFDLFWPTVRP----------------------------------
MMAR_4834|M.marinum_M -----IVDDFLVAHRRQADKPAQRAVSRKPVSRRSGSD------------
MAV_3805|M.avium_104 -----IVEGFIAAQT--GDQPAWVEAS-SPNQ------------------
MAB_3565|M.abscessus_ATCC_1997 -----ATQITLTAARAGLLSA-----------------------------
Mb1998c|M.bovis_AF2122/97 AVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEIS
Rv1255c|M.tuberculosis_H37Rv -----IVTPASAAARKAGHPGPE---------------------------
MLBr_00949|M.leprae_Br4923 --------------------------------------------------
MUL_1299|M.ulcerans_Agy99 -------EALAAELTYSLNGYLA---------------------------
Mvan_0230|M.vanbaalenii_PYR-1 -----------------
Mflv_0437|M.gilvum_PYR-GCK -----------------
MSMEG_0986|M.smegmatis_MC2_155 -----------------
TH_1099|M.thermoresistible__bu -----------------
MMAR_4834|M.marinum_M -----------------
MAV_3805|M.avium_104 -----------------
MAB_3565|M.abscessus_ATCC_1997 -----------------
Mb1998c|M.bovis_AF2122/97 GLALAILTSGAGNLLRA
Rv1255c|M.tuberculosis_H37Rv -----------------
MLBr_00949|M.leprae_Br4923 -----------------
MUL_1299|M.ulcerans_Agy99 -----------------