For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AANSGDDVGARILDAALELLRARGPKAVTMQAVVDATGIAKTTIYRRHPNRRTLLAAALETLGERPSVPA DATRHERLNWVITQSVDVIAHGIGAGGFAALLTDDDPEFSDAFRAILGAYRRHAIDALDVDVATGETVID LIVGGYVAELARTGSVDDGWNARMADAVERVLPSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0437 | - | - | 100% (176) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5054 | - | 9e-10 | 40.24% (82) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3683 | - | 1e-08 | 46.67% (60) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 8e-06 | 37.18% (78) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv3574 | - | 8e-06 | 37.18% (78) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2606c | - | 2e-07 | 38.71% (62) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4834 | - | 3e-07 | 50.00% (52) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3805 | - | 1e-09 | 40.24% (82) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0986 | - | 1e-36 | 49.06% (159) | RemM protein |
| M. thermoresistible (build 8) | TH_1099 | - | 1e-32 | 44.05% (168) | RemM protein |
| M. ulcerans Agy99 | MUL_1299 | - | 4e-07 | 36.21% (58) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0230 | - | 3e-71 | 77.46% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0437|M.gilvum_PYR-GCK --------------MAANSGDDVGARILDAALELLRARGPKAVTMQAVVD
Mvan_0230|M.vanbaalenii_PYR-1 ----MRRQQHRRRQMAAQSTDEVGARILDAALELLRARGPRAVTMQAIVD
MSMEG_0986|M.smegmatis_MC2_155 --------------MADRR--RVEDGIAESTLHLLRSGGPRAVTVEAVTS
TH_1099|M.thermoresistible__bu --------------MAVR---DVDDGIADATLALLRTKGPRSATVQAVAA
MMAR_4834|M.marinum_M MERDTLEFPVDDDDDVDPRRLRSRTRLLDAATKLLSAGGIEAVTIDAVTK
MAV_3805|M.avium_104 MGTQPAETP-DDEDDVDPRRTRSRTRLLDAAANLLKTGGIEAVTIDAVTK
Mb3605|M.bovis_AF2122/97 ------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVAD
Rv3574|M.tuberculosis_H37Rv ------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVAD
MAB_2606c|M.abscessus_ATCC_199 -----MTAVFDEGSAPESDGDSVTTRLLDATEKLLADKGIRATTMTDVAE
MUL_1299|M.ulcerans_Agy99 ------------MLSMSNAPEDIGDRILQAAASCVRDYGVDRVTLAEIAR
: ::: * . : :.
Mflv_0437|M.gilvum_PYR-GCK ATGIAKTTIYRRHPNRRTLLAAALETLGERPSVPA---------------
Mvan_0230|M.vanbaalenii_PYR-1 ATGIAKTTIYRRHQNRRMLLTAALETLGERPSAPP---------------
MSMEG_0986|M.smegmatis_MC2_155 HSGIAKTTIYRRHHNRREMLAAALSGLATPESLDPGAESTLHLLRSGGPR
TH_1099|M.thermoresistible__bu QSGIAKTTIYRRFRDRRDMLSAALSRVAHPDPLEP---------------
MMAR_4834|M.marinum_M ASKVARTTLYRHFSSSTQLLAATFERLLPQVHPP----------------
MAV_3805|M.avium_104 ASKVARTTLYRHFNSSSQLLAATFERLLPQVIPPA---------------
Mb3605|M.bovis_AF2122/97 RADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDR-------------
Rv3574|M.tuberculosis_H37Rv RADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDR-------------
MAB_2606c|M.abscessus_ATCC_199 EAGVSRSWLYRHFPDKPTLVGAAIIRLIEVSWAQS---------------
MUL_1299|M.ulcerans_Agy99 RAGVSRPTVYRRWPDTRSIISALLTSHVTDVVRAVFL-------------
: :: :** . :: : :
Mflv_0437|M.gilvum_PYR-GCK --------------------------------------------DATRHE
Mvan_0230|M.vanbaalenii_PYR-1 --------------------------------------------ESGRAE
MSMEG_0986|M.smegmatis_MC2_155 AVTVEAVTSHSGIAKTTIYRRHHNRREMLAAALSGLATPESLDPGADAPD
TH_1099|M.thermoresistible__bu --------------------------------------------DTAAPD
MMAR_4834|M.marinum_M ------------------------------------------PATGSMRD
MAV_3805|M.avium_104 ------------------------------------------PTSGTLRE
Mb3605|M.bovis_AF2122/97 ----------------------------------------SAVAGATPFQ
Rv3574|M.tuberculosis_H37Rv ----------------------------------------SAVAGATPFQ
MAB_2606c|M.abscessus_ATCC_199 ------------------------------------------AAELADID
MUL_1299|M.ulcerans_Agy99 --------------------------------------------DGHDRQ
:
Mflv_0437|M.gilvum_PYR-GCK RLNWVITQSVDVIAHG---IGAGGFAALLTDDDPEFSDAFRA--------
Mvan_0230|M.vanbaalenii_PYR-1 RLQWVITQSVDVIAAG---IGAGGFAALLTDEDPEFSEAFRA--------
MSMEG_0986|M.smegmatis_MC2_155 RLRWVIAQAIGTIEDG---IGIGGLAALCTEDDPEFNTLFRR--------
TH_1099|M.thermoresistible__bu RLRWLIAQAVKTIEVG---IGYGGFAAMLTDEDPDFTAVFRE--------
MMAR_4834|M.marinum_M QLIELLSRQATLFQEAPLHVTTLAWVALGPTPDGTQETQDRH---ALRAR
MAV_3805|M.avium_104 RLIELLSRQADLFAEAPVQVTTLAWAALGPAETHEPNTVQHAGAGTLRMR
Mb3605|M.bovis_AF2122/97 RLNFMVGKLNRAMQRNP--LLTEAMTRAYVFADASAASEVDQ--------
Rv3574|M.tuberculosis_H37Rv RLNFMVGKLNRAMQRNP--LLTEAMTRAYVFADASAASEVDQ--------
MAB_2606c|M.abscessus_ATCC_199 GFEARLVAGVKIGRRAYDDPGTLLMRIRLREPEEFMACAGTG-----VQG
MUL_1299|M.ulcerans_Agy99 TVVRQVVAVADRLRGDELVKALMHSDLARVYITERLGASQHF--------
. :
Mflv_0437|M.gilvum_PYR-GCK ILGAYRRHAIDALDVDVATG--------ETVIDLIVGGYVAELARTGSVD
Mvan_0230|M.vanbaalenii_PYR-1 ILVAYRRQAIDALAIGDRVG--------DTLVDIIVGSYVAELARTGSID
MSMEG_0986|M.smegmatis_MC2_155 ILVEQRAALAEVIDAAKTDGSMRDDVDAQTLIDAVVGAYIAESARTGAVA
TH_1099|M.thermoresistible__bu ILAGQRAELEAVIDGGKADGSIRADVDGSALIDAVVGTHIAERARVGEVA
MMAR_4834|M.marinum_M IIDQYRQPFVALLQSPEARADLDDFDMELILCQLIGPVAFARLTGLRAID
MAV_3805|M.avium_104 VIEQYRRPFDEILYSPESVDQLGELDIELALCQLVGPLVFARMTGLRVIT
Mb3605|M.bovis_AF2122/97 VEKLIDSMFARAMANGEPTED--QYHIARVISDVWLSNLLAWLTRRASAT
Rv3574|M.tuberculosis_H37Rv VEKLIDSMFARAMANGEPTED--QYHIARVISDVWLSNLLAWLTRRASAT
MAB_2606c|M.abscessus_ATCC_199 LVPDLAGFWRPYLEAARDTGEIHALTDIEEASEWIARVMISLGSVPGNRI
MUL_1299|M.ulcerans_Agy99 LLEGLAARLQVAQGTGSVRAG-----DPRKLAAMVLLITQSTIQSVDIID
: :
Mflv_0437|M.gilvum_PYR-GCK DGWNARMADAVERVLPSR---------------------
Mvan_0230|M.vanbaalenii_PYR-1 DGWAARIAAVLDGVLDAAAND------------------
MSMEG_0986|M.smegmatis_MC2_155 DGWQERLFALFWPIVRASA--------------------
TH_1099|M.thermoresistible__bu ADWENRLFDLFWPTVRP----------------------
MMAR_4834|M.marinum_M RQDCERIVDDFLVAHRRQADKPAQRAVSRKPVSRRSGSD
MAV_3805|M.avium_104 HQDCTRIVEGFIAAQT--GDQPAWVEAS-SPNQ------
Mb3605|M.bovis_AF2122/97 DVSKRLDLAVRLLIGDQDSA-------------------
Rv3574|M.tuberculosis_H37Rv DVSKRLDLAVRLLIGDQDSA-------------------
MAB_2606c|M.abscessus_ATCC_199 DPDDPASLRRHFRRYVLPALRIAPVK-------------
MUL_1299|M.ulcerans_Agy99 PILDSEALAAELTYSLNGYLA------------------