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MTGTVSYDLADSVATVTLDDGKVNVLGPAMQAAINNALDRAEADKAKAVVLAGNSRVFSGGFDLGVFQSG DAAAALGMLSGGFELSVRTLTFPVPVIIAATGPAIAMGSFLLLSGDHRVGQPKTRCQAIEVAIGMTIPIA ALEIMRARLTPAAFERSAALASTYVGDDAVAAGWLDEIVEADQVLTRAQQVAAEAATTLHAGAHLATKLK ARKYALDAIRAGIDGLATEFTLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5125 | - | - | 100% (233) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1692 | - | 8e-10 | 29.52% (210) | 3-hydroxyacyl-CoA dehydrogenase, NAD-binding |
| M. gilvum PYR-GCK | Mflv_1880 | - | 2e-09 | 29.39% (245) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0649c | echA3 | 4e-66 | 55.60% (232) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0632c | echA3 | 4e-66 | 55.60% (232) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02498 | - | 9e-09 | 27.51% (189) | putative enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0981c | - | 6e-11 | 29.56% (159) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_0962 | echA3 | 3e-68 | 57.33% (232) | enoyl-CoA hydratase, EchA3 |
| M. avium 104 | MAV_4534 | - | 1e-67 | 56.90% (232) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_1331 | - | 7e-88 | 71.79% (234) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_1874 | echA3 | 5e-95 | 74.25% (233) | PROBABLE ENOYL-CoA HYDRATASE ECHA3 (ENOYL HYDRASE) |
| M. ulcerans Agy99 | MUL_0713 | echA3 | 2e-68 | 57.33% (232) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1226 | - | 1e-112 | 88.41% (233) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5125|M.gilvum_PYR-GCK MTGTVSYDLADSVATVTLDDGKVNVLGPAMQAAINNALDR----AEADKA
Mvan_1226|M.vanbaalenii_PYR-1 MTSTVSYEFADSVATISLDDGKVNVLGPAMQAAINEALDR----AEADKA
MSMEG_1331|M.smegmatis_MC2_155 MSSLVSYALNGNVATVTLDDGKANALSPDMQAAINDALDQASLAAGSGEV
TH_1874|M.thermoresistible__bu MSSTVEYQLTDSVATITMDDGKVNVLSPAMQGNLNEALDR----AEQDGA
Mb0649c|M.bovis_AF2122/97 MSDPVSYTRKDSIAVISMDDGKVNALGPAMQQALNAAIDN----ADRDDV
Rv0632c|M.tuberculosis_H37Rv MSDPVSYTRKDSIAVISMDDGKVNALGPAMQQALNAAIDN----ADRDDV
MMAR_0962|M.marinum_M MSGPVTYTHDDAIGVIRMDDGKVNVLGPTMQQALNEAIDA----ADRDNV
MUL_0713|M.ulcerans_Agy99 MSGPVTYTHDDAIGVIRMDDGKVNVLGPTMQQALNEAIDA----ADRDNV
MAV_4534|M.avium_104 MSGPVHYSTKGPVAVIRMDDGKVNALGPTMQQALGEAIDR----AEADNA
MLBr_02498|M.leprae_Br4923 MTIAVHYD--EKIAILELGD-DENRFTSVFLEEINSHLDE---IIASG-A
MAB_0981c|M.abscessus_ATCC_199 MSATLTRD--GAIATLVLGT-DENRFTLPFIDEVNARIDE---IVADEEP
*: : :. : :. . * : : :. :*
Mflv_5125|M.gilvum_PYR-GCK KAVVLAGNSRVFSGGFDLGVFQSGDAAAALGMLSGGFELSVRTLTFPVPV
Mvan_1226|M.vanbaalenii_PYR-1 KAVVLAGNSRVFSGGFDLSVFQSGDAAAALGMLAGGFELSLRTLTFPAPV
MSMEG_1331|M.smegmatis_MC2_155 KALVVAGNSKVFSGGFDLSVFASGDAAAALGMLTGGFELAVRCLTFPVPV
TH_1874|M.thermoresistible__bu KAVVLAGNSRVFSGGFDLSVFSSGDVDAALGMLRGGFELAVRALTFPVPV
Mb0649c|M.bovis_AF2122/97 GALVITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLLSYPKPV
Rv0632c|M.tuberculosis_H37Rv GALVITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLLSYPKPV
MMAR_0962|M.marinum_M GALVIAGNHRVFSGGFDLKVLTSGEAKPAIDMLRGGFELSYRLLSYPKPV
MUL_0713|M.ulcerans_Agy99 GALVIAGNHRVFSGGFDLKVLTSGEAKPAIDMLRGGFELSYRLLSYPKPV
MAV_4534|M.avium_104 GALVITGNERVFSGGFDLKILTSGEVQPAVNMLRGGFELAYRLLSYPKPV
MLBr_02498|M.leprae_Br4923 NGLVTTALGKFYSNGLDLDWLS-AHRDQTQWYVGKVQGLLARLLTLPIPT
MAB_0981c|M.abscessus_ATCC_199 TALVVTGSGKFFSNGLDVEYLG-ANPDKLGWYITEVQKIFVRLLTLPVPT
.:* :. :.:*.*:*: : .. : : * *: * *.
Mflv_5125|M.gilvum_PYR-GCK IIAATGPAIAMGSFLLLSGDHRVG-QPKTRCQAIEVAIGMTIPIAALEIM
Mvan_1226|M.vanbaalenii_PYR-1 IVAATGPAIAMGSFLLLSTDHRVG-QPKSRCQAIEVAIGMTIPISALEIM
MSMEG_1331|M.smegmatis_MC2_155 IMAATGPAIAMGSFLLLSGDHRVG-SPRSRCQANEVAIGMTLPIAAIEIM
TH_1874|M.thermoresistible__bu IMAATGPAIAMGSFLLLCGDHRVG-SERTRCQANEVAIGMILPVAALEIM
Mb0649c|M.bovis_AF2122/97 VMACTGHAIAMGAFLLSCGDHRVA-AHAYNIQANEVAIGMTIPYAALEIM
Rv0632c|M.tuberculosis_H37Rv VMACTGHAIAMGAFLLSCGDHRVA-AHAYNIQANEVAIGMTIPYAALEIM
MMAR_0962|M.marinum_M VIACTGHAIAMGAFLLCSGDHRVA-AHAYNVQANEVAIGMTIPYAAMEVL
MUL_0713|M.ulcerans_Agy99 VIACTGHAIAMGAFLLCSGDHRVA-AHAYNIQANEVAIGMTIPYAAMEVL
MAV_4534|M.avium_104 VMACTGHAIAMGAFLLSSGDHRVA-AHAYNIQANEVAIGMVIPYAAMEIM
MLBr_02498|M.leprae_Br4923 AAAVVGHAFGAGAMLAMAHDFRVMRADRGYFCFPEVDIRIPFTPGMAALI
MAB_0981c|M.abscessus_ATCC_199 VAAVNGHAYGAGAMVALSCDYRVMRSDRGFFCLPEVNVGLPFTPGMSALC
* * * . *::: . *.** ** : : :. . :
Mflv_5125|M.gilvum_PYR-GCK RARLTPAAFERSAALASTYVGDDAVAAGWLDEIVEADQVLTRAQQVAAEA
Mvan_1226|M.vanbaalenii_PYR-1 RMRLTPAAFERGAALAATFAGDDAVAGGWLDEIVPADQVLARAQQVAGEA
MSMEG_1331|M.smegmatis_MC2_155 RMRLTRAAFQRAISMAAVFSGDAAISAGWLDEIVEPDEVLDRAQQVATEA
TH_1874|M.thermoresistible__bu RMRLTPAAYQHAVSLATTFTGDAAIRAGWLDEVVDTDRVLPRAREFAAEV
Mb0649c|M.bovis_AF2122/97 KLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEEAAREF
Rv0632c|M.tuberculosis_H37Rv KLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEEAAREF
MMAR_0962|M.marinum_M KLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVLSRAEEAAREF
MUL_0713|M.ulcerans_Agy99 KLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVLSRAEEAAREF
MAV_4534|M.avium_104 KLRLTPSAYQQASGLAKTFFGETALAAGFVDEIVLPEVVVDRAEEAAAEF
MLBr_02498|M.leprae_Br4923 QAKLAPQAATASMTTGRRFGGGEAARLGIVDNTAAEDAVTAVAVDLLHPL
MAB_0981c|M.abscessus_ATCC_199 QGRMTPQAASATMPSGQRYGGDDCVRLQIVDAAVLEDEVISTAKGFVEPL
: ::: * . : * . :* : * *
Mflv_5125|M.gilvum_PYR-GCK ATTLHAGAHLATKLKARKYALDAIRAGIDGLATEFTLG
Mvan_1226|M.vanbaalenii_PYR-1 AATLHPGAHLATKLKARKPALDAIRAGIDGLATEFSLG
MSMEG_1331|M.smegmatis_MC2_155 AA-LHTNAHVASKLKARADAVTAIRAGIDGLAAEFGS-
TH_1874|M.thermoresistible__bu ATTVHAHAHLASKLKARDAALKAIRAGIDGIATEFTGG
Mb0649c|M.bovis_AF2122/97 AG-LNQHAHAATKLRSRADALTAIRAGIDGIAAEFGL-
Rv0632c|M.tuberculosis_H37Rv AG-LNQHAHAATKLRSRADALTAIRAGIDGIAAEFGL-
MMAR_0962|M.marinum_M AG-LNQQAHNATKLRARAEALKAIRAGIDGIEAEFGL-
MUL_0713|M.ulcerans_Agy99 AG-LNQQAHNATKLRARAEALKAIRAGIDGIEAEFGL-
MAV_4534|M.avium_104 AE-LNQRAHAATKLRARADALAAIRAGIDGIEAEFGL-
MLBr_02498|M.leprae_Br4923 GG-KDPGTLGVIKQTMFGHAAAALSANA----------
MAB_0981c|M.abscessus_ATCC_199 VG-KNRGTLSTIKNGMYSSIVPLLLAGLG---------
. : . * : *.