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SATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGLDVEYLGANPDK LGWYITEVQKIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSDRGFFCLPEVNVGLPFTPGMSA LCQGRMTPQAASATMPSGQRYGGDDCVRLQIVDAAVLEDEVISTAKGFVEPLVGKNRGTLSTIKNGMYSS IVPLLLAGLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0981c | - | - | 100% (221) | enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_2465c | - | 8e-56 | 47.25% (218) | enoyl-coa hydratase/isomerase family protein |
| M. abscessus ATCC 19977 | MAB_2737c | - | 4e-13 | 27.27% (187) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3065c | echA17 | 6e-12 | 27.18% (206) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3669 | - | 1e-13 | 28.27% (191) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3039c | echA17 | 6e-12 | 27.18% (206) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02498 | - | 2e-60 | 52.13% (211) | putative enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 5e-13 | 27.19% (228) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_2558 | - | 7e-13 | 31.06% (161) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_6558 | - | 1e-58 | 51.39% (216) | putative enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2890 | - | 3e-14 | 28.71% (202) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 2e-12 | 26.75% (228) | enoyl-CoA hydratase, EchA8_5 |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 3e-14 | 29.55% (220) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3510|M.marinum_M -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGKDFIAA
MUL_2758|M.ulcerans_Agy99 -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGRDFIAA
Mvan_2877|M.vanbaalenii_PYR-1 MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAA
Mflv_3669|M.gilvum_PYR-GCK ------------------------------------------MAFDVMVP
Mb3065c|M.bovis_AF2122/97 ------------MPEFVNVVVSDGSQDAGLAMLLLSRPPTNAMTRQVYRE
Rv3039c|M.tuberculosis_H37Rv ------------MPEFVNVVVSDGSQDAGLAMLLLSRPPTNAMTRQVYRE
MLBr_02498|M.leprae_Br4923 -------------------MTIAVHYDEKIAILELGD-DENRFTSVFLEE
MSMEG_6558|M.smegmatis_MC2_155 -------------------MTATLDYDGDIAVLDLGD-DENRFTPQFLDE
MAB_0981c|M.abscessus_ATCC_199 -------------------MSATLTRDGAIATLVLGT-DENRFTLPFIDE
MAV_2558|M.avium_104 -MTTSEIATLPGYEEFAPWLLVEKRGNVHVVSINRPE-AFNAVNEQVHHA
TH_2890|M.thermoresistible__bu -------------VTADAPLVLREDRGAVALLWLNRAAQRNALRYESWTE
MMAR_3510|M.marinum_M FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
MUL_2758|M.ulcerans_Agy99 FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
Mvan_2877|M.vanbaalenii_PYR-1 FESAVDTANSDVAVRAVILTGAGKIFSAGGNVKEMADRQGMFGLDAIAQR
Mflv_3669|M.gilvum_PYR-GCK LKAALDELTYDNDVRAVVLTGAGHGFSSGADHKSAGSVPHVDGLTRPAFG
Mb3065c|M.bovis_AF2122/97 VVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIR
Rv3039c|M.tuberculosis_H37Rv VVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIR
MLBr_02498|M.leprae_Br4923 INSHLDEIIASG-ANGLVTTALGKFYSNGLDLDWLSAHR--------DQT
MSMEG_6558|M.smegmatis_MC2_155 VDALLDAVLEKG-AHGLVTTADSKFYSNGLDLEWLGAHS--------DQG
MAB_0981c|M.abscessus_ATCC_199 VNARIDEIVADEEPTALVVTGSGKFFSNGLDVEYLGANP--------DKL
MAV_2558|M.avium_104 FATIWRVLTADDDVRAVVTTGVGKAFSAGGDMVMFGRLID-----DAVAR
TH_2890|M.thermoresistible__bu LSEHLAVLAEDPDVRGVXVAGAGGFFSAGGDLKTGPAHGAG-----PLGP
. .: . :* * :
MMAR_3510|M.marinum_M QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
MUL_2758|M.ulcerans_Agy99 QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
Mvan_2877|M.vanbaalenii_PYR-1 HAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCDIRVASERAS
Mflv_3669|M.gilvum_PYR-GCK LRSMEVLDDVILALRKLHQPVIAAVNGAAIGGGLCLALAADIRVASTSAY
Mb3065c|M.bovis_AF2122/97 QQAVDAVAAIP-------KPTVAAITGYALGAGLTLALAADWRVSGDNVK
Rv3039c|M.tuberculosis_H37Rv QQAVDAVAAIP-------KPTVAAITGYALGAGLTLALAADWRVSGDNVK
MLBr_02498|M.leprae_Br4923 QWYVGKVQGLLARLLTLPIPTAAAVVGHAFGAGAMLAMAHDFRVMRADRG
MSMEG_6558|M.smegmatis_MC2_155 AWYVGRVQGLLARVLTFPLPTAAAVVGHAFGAGAMLAMAHDYRVMREDRG
MAB_0981c|M.abscessus_ATCC_199 GWYITEVQKIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSDRG
MAV_2558|M.avium_104 QFQISEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGESSY
TH_2890|M.thermoresistible__bu AGRVEHAQRVMEQLKAVPVPTVAAVEGAAVGLGWSLALACDLVVAASDAF
: * .*: * * * * :* * :
MMAR_3510|M.marinum_M FAESFVALGIIPGDGG-TWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
MUL_2758|M.ulcerans_Agy99 FAESFVALGIIPGDGG-TWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
Mvan_2877|M.vanbaalenii_PYR-1 FAESFVQIGLVPGDGG-TWFLQRAIGYERAAEMTLTGDRIDAATALEWGL
Mflv_3669|M.gilvum_PYR-GCK FRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVDAEEAERIGL
Mb3065c|M.bovis_AF2122/97 FGATEILAGLIPSGDG-MARLTRAAGPSRAKELVFSGRFFDAEEALALGL
Rv3039c|M.tuberculosis_H37Rv FGATEILAGLIPSGDG-MARLTRAAGPSRAKELVFSGRFFDAEEALALGL
MLBr_02498|M.leprae_Br4923 YFCFPEVDIRIPFTPGMAALIQAKLAPQAATASMTTGRRFGGGEAARLGI
MSMEG_6558|M.smegmatis_MC2_155 FFCFPEVDIHIPFTPGMAALIQAKLTPQAAIASMTTGRRFGGSEAHEHGI
MAB_0981c|M.abscessus_ATCC_199 FFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQRYGGDDCVRLQI
MAV_2558|M.avium_104 LADPHVAVGLVAGDGG-AAMLPLLIGLMKAKEYVLLGDRITPAIADKLNL
TH_2890|M.thermoresistible__bu FSAPFVARAVVP-DGGLAWRLTHQLGRQRASALLLRGSRLAAPDAAQAGL
. * * * . :
MMAR_3510|M.marinum_M VSRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQE-SRVGSLESTLG
MUL_2758|M.ulcerans_Agy99 VSRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQE-SRVGSLESTLG
Mvan_2877|M.vanbaalenii_PYR-1 VSRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQE-SRTGVLESTLG
Mflv_3669|M.gilvum_PYR-GCK VSRRVADEDLLETCYELAERIAGFSRPGTELTKRTLWSGLDAGSLEAHMQ
Mb3065c|M.bovis_AF2122/97 IDDMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISD---VYELAPAER
Rv3039c|M.tuberculosis_H37Rv IDDMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISD---VYELAPAER
MLBr_02498|M.leprae_Br4923 VDNTAAEDAVTAVAVDLLHPLGGKDPGTLGVIKQTMFG-----HAAAALS
MSMEG_6558|M.smegmatis_MC2_155 VDATAHEGAVTLAATSLLRPLGSKDQGTLGAIKQVMFG-----AAAAALR
MAB_0981c|M.abscessus_ATCC_199 VDAAVLEDEVISTAKGFVEPLVGKNRGTLSTIKNGMYS-----SIVPLLL
MAV_2558|M.avium_104 VTKVATDDTVLDEALAIGERLAGLPPQALRASKVAMNM--HLSRAALGVL
TH_2890|M.thermoresistible__bu VTELAELGSAVEVALALLDELASADAGAVEMTKRLINS------VEAAQL
: . . : * :
MMAR_3510|M.marinum_M MAAAMQPLAHRDPE-HQQRIAKWRTR---------
MUL_2758|M.ulcerans_Agy99 MAAAMQPLAHRDPE-HQQRIAKWRTRIAKWRTR--
Mvan_2877|M.vanbaalenii_PYR-1 MAAAMQPLAHRDPE-HAARISRWRSS---------
Mflv_3669|M.gilvum_PYR-GCK AEGLGQLYIRLLTDNFEEAVAARREKRAPRFSDDR
Mb3065c|M.bovis_AF2122/97 IAAERRRYVEVFAAGQGGGSKGDRGGR--------
Rv3039c|M.tuberculosis_H37Rv IAAERRRYVEVFAAGQGGGSKGDRGGR--------
MLBr_02498|M.leprae_Br4923 ANA--------------------------------
MSMEG_6558|M.smegmatis_MC2_155 NP---------------------------------
MAB_0981c|M.abscessus_ATCC_199 AGLG-------------------------------
MAV_2558|M.avium_104 EYALAEEYTSFSTPEFKERVAAFRARSKK------
TH_2890|M.thermoresistible__bu AAFHPLELAMATVAQQRSASAAARDRW--------