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M. avium 104 MAV_4534 (-)

annotation: enoyl-CoA hydratase
coordinates: 4660072 - 4660767
length: 231

MSGPVHYSTKGPVAVIRMDDGKVNALGPTMQQALGEAIDRAEADNAGALVITGNERVFSGGFDLKILTSG
EVQPAVNMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSSGDHRVAAHAYNIQANEVAIGMVIPYA
AMEIMKLRLTPSAYQQASGLAKTFFGETALAAGFVDEIVLPEVVVDRAEEAAAEFAELNQRAHAATKLRA
RADALAAIRAGIDGIEAEFGL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4534--100% (231)enoyl-CoA hydratase
M. avium 104MAV_3904-2e-1426.73% (217) enoyl-CoA hydratase
M. avium 104MAV_0967-3e-1233.15% (184) enoyl-CoA hydratase/isomerase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0649cechA31e-10885.71% (231) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_5125-1e-6756.90% (232) enoyl-CoA hydratase
M. tuberculosis H37RvRv0632cechA31e-10885.71% (231) enoyl-CoA hydratase
M. leprae Br4923MLBr_01724-4e-1125.81% (217) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_4588c-6e-1129.73% (185) enoyl-CoA hydratase/isomerase
M. marinum MMMAR_0962echA31e-10783.12% (231) enoyl-CoA hydratase, EchA3
M. smegmatis MC2 155MSMEG_1331-7e-6955.56% (234) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_1874echA33e-7059.57% (230) PROBABLE ENOYL-CoA HYDRATASE ECHA3 (ENOYL HYDRASE)
M. ulcerans Agy99MUL_0713echA31e-10783.55% (231) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_1226-3e-6656.03% (232) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5125|M.gilvum_PYR-GCK          MTGTVSYDLADS-----VATVTLDD-GKVNVLGPAMQAAINNALDR----
Mvan_1226|M.vanbaalenii_PYR-1       MTSTVSYEFADS-----VATISLDD-GKVNVLGPAMQAAINEALDR----
MSMEG_1331|M.smegmatis_MC2_155      MSSLVSYALNGN-----VATVTLDD-GKANALSPDMQAAINDALDQASLA
TH_1874|M.thermoresistible__bu      MSSTVEYQLTDS-----VATITMDD-GKVNVLSPAMQGNLNEALDR----
MMAR_0962|M.marinum_M               MSGPVTYTHDDA-----IGVIRMDD-GKVNVLGPTMQQALNEAIDA----
MUL_0713|M.ulcerans_Agy99           MSGPVTYTHDDA-----IGVIRMDD-GKVNVLGPTMQQALNEAIDA----
Mb0649c|M.bovis_AF2122/97           MSDPVSYTRKDS-----IAVISMDD-GKVNALGPAMQQALNAAIDN----
Rv0632c|M.tuberculosis_H37Rv        MSDPVSYTRKDS-----IAVISMDD-GKVNALGPAMQQALNAAIDN----
MAV_4534|M.avium_104                MSGPVHYSTKGP-----VAVIRMDD-GKVNALGPTMQQALGEAIDR----
MAB_4588c|M.abscessus_ATCC_199      MADEVLIEQRDR-----VLLITINRPDARNAVNRAVSQGLAAAADQ---L
MLBr_01724|M.leprae_Br4923          MSEFVNIVVSDGSQDAGLAILLLSR-PPTNAMTRQFYREIAMAADEL---
                                    *:  *     .      :  : :.     *.:   .   :  * *     

Mflv_5125|M.gilvum_PYR-GCK          AEADKAKAVVLAGNSRVFSGGFDLGVFQSGDAAAALGMLSGGFELSVRTL
Mvan_1226|M.vanbaalenii_PYR-1       AEADKAKAVVLAGNSRVFSGGFDLSVFQSGDAAAALGMLAGGFELSLRTL
MSMEG_1331|M.smegmatis_MC2_155      AGSGEVKALVVAGNSKVFSGGFDLSVFASGDAAAALGMLTGGFELAVRCL
TH_1874|M.thermoresistible__bu      AEQDGAKAVVLAGNSRVFSGGFDLSVFSSGDVDAALGMLRGGFELAVRAL
MMAR_0962|M.marinum_M               ADRDNVGALVIAGNHRVFSGGFDLKVLTSGEAKPAIDMLRGGFELSYRLL
MUL_0713|M.ulcerans_Agy99           ADRDNVGALVIAGNHRVFSGGFDLKVLTSGEAKPAIDMLRGGFELSYRLL
Mb0649c|M.bovis_AF2122/97           ADRDDVGALVITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLL
Rv0632c|M.tuberculosis_H37Rv        ADRDDVGALVITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLL
MAV_4534|M.avium_104                AEADNAGALVITGNERVFSGGFDLKILTSGEVQPAVNMLRGGFELAYRLL
MAB_4588c|M.abscessus_ATCC_199      DSSADLSVAIITGAGGNFCAGMDLKAFVSGEAVLSE---RG---LGFTNV
MLBr_01724|M.leprae_Br4923          GRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQAVDAVA
                                           . :: *    *..* *:  : :  .  :               

Mflv_5125|M.gilvum_PYR-GCK          TFPVPVIIAATGPAIAMGSFLLLSGDHRVGQPKTRCQAIEVAIGMTIPIA
Mvan_1226|M.vanbaalenii_PYR-1       TFPAPVIVAATGPAIAMGSFLLLSTDHRVGQPKSRCQAIEVAIGMTIPIS
MSMEG_1331|M.smegmatis_MC2_155      TFPVPVIMAATGPAIAMGSFLLLSGDHRVGSPRSRCQANEVAIGMTLPIA
TH_1874|M.thermoresistible__bu      TFPVPVIMAATGPAIAMGSFLLLCGDHRVGSERTRCQANEVAIGMILPVA
MMAR_0962|M.marinum_M               SYPKPVVIACTGHAIAMGAFLLCSGDHRVAAHAYNVQANEVAIGMTIPYA
MUL_0713|M.ulcerans_Agy99           SYPKPVVIACTGHAIAMGAFLLCSGDHRVAAHAYNIQANEVAIGMTIPYA
Mb0649c|M.bovis_AF2122/97           SYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYNIQANEVAIGMTIPYA
Rv0632c|M.tuberculosis_H37Rv        SYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYNIQANEVAIGMTIPYA
MAV_4534|M.avium_104                SYPKPVVMACTGHAIAMGAFLLSSGDHRVAAHAYNIQANEVAIGMVIPYA
MAB_4588c|M.abscessus_ATCC_199      PPRKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRGLVAGAG
MLBr_01724|M.leprae_Br4923          TIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILADLVPDGD
                                    .   * : *  * *:. *  *  . *  *.    .    *:  .:     

Mflv_5125|M.gilvum_PYR-GCK          ALEIMRARLTPAAFERSAALASTYVGDDAVAAGWLDEIVEADQVLTRAQQ
Mvan_1226|M.vanbaalenii_PYR-1       ALEIMRMRLTPAAFERGAALAATFAGDDAVAGGWLDEIVPADQVLARAQQ
MSMEG_1331|M.smegmatis_MC2_155      AIEIMRMRLTRAAFQRAISMAAVFSGDAAISAGWLDEIVEPDEVLDRAQQ
TH_1874|M.thermoresistible__bu      ALEIMRMRLTPAAYQHAVSLATTFTGDAAIRAGWLDEVVDTDRVLPRARE
MMAR_0962|M.marinum_M               AMEVLKLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVLSRAEE
MUL_0713|M.ulcerans_Agy99           AMEVLKLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVLSRAEE
Mb0649c|M.bovis_AF2122/97           ALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEE
Rv0632c|M.tuberculosis_H37Rv        ALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEE
MAV_4534|M.avium_104                AMEIMKLRLTPSAYQQASGLAKTFFGETALAAGFVDEIVLPEVVVDRAEE
MAB_4588c|M.abscessus_ATCC_199      GLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQALDTALE
MLBr_01724|M.leprae_Br4923          GLARLTRVAGVSRAKDLVFSGRFFDAAEALALGLIDDMVAPDDVYDIAAA
                                    .:  :               .  : .  *   * :: :     .   *  

Mflv_5125|M.gilvum_PYR-GCK          VAAEAATT-----------------------LHAGAHLATKLKARKYALD
Mvan_1226|M.vanbaalenii_PYR-1       VAGEAAAT-----------------------LHPGAHLATKLKARKPALD
MSMEG_1331|M.smegmatis_MC2_155      VATEAAA------------------------LHTNAHVASKLKARADAVT
TH_1874|M.thermoresistible__bu      FAAEVATT-----------------------VHAHAHLASKLKARDAALK
MMAR_0962|M.marinum_M               AAREFAG------------------------LNQQAHNATKLRARAEALK
MUL_0713|M.ulcerans_Agy99           AAREFAG------------------------LNQQAHNATKLRARAEALK
Mb0649c|M.bovis_AF2122/97           AAREFAG------------------------LNQHAHAATKLRSRADALT
Rv0632c|M.tuberculosis_H37Rv        AAREFAG------------------------LNQHAHAATKLRSRADALT
MAV_4534|M.avium_104                AAAEFAE------------------------LNQRAHAATKLRARADALA
MAB_4588c|M.abscessus_ATCC_199      LAAKITANGPLAVAATKRIIIESASWAPEEAFAKQGEILMPIFVSEDAKE
MLBr_01724|M.leprae_Br4923          WARRFLDGLPHALAAAKAG------------INEVFDLEPAERIAAERRR
                                     * .                           .    .             

Mflv_5125|M.gilvum_PYR-GCK          AIRAGIDGLATEFTLG--
Mvan_1226|M.vanbaalenii_PYR-1       AIRAGIDGLATEFSLG--
MSMEG_1331|M.smegmatis_MC2_155      AIRAGIDGLAAEFGS---
TH_1874|M.thermoresistible__bu      AIRAGIDGIATEFTGG--
MMAR_0962|M.marinum_M               AIRAGIDGIEAEFGL---
MUL_0713|M.ulcerans_Agy99           AIRAGIDGIEAEFGL---
Mb0649c|M.bovis_AF2122/97           AIRAGIDGIAAEFGL---
Rv0632c|M.tuberculosis_H37Rv        AIRAGIDGIAAEFGL---
MAV_4534|M.avium_104                AIRAGIDGIEAEFGL---
MAB_4588c|M.abscessus_ATCC_199      GAKAFAEKRAPVWQGK--
MLBr_01724|M.leprae_Br4923          YVEVFAAAQPSLLLGGCD
                                      ..      .