For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1874 | echA3 | - | 100% (234) | PROBABLE ENOYL-CoA HYDRATASE ECHA3 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE) |
| M. thermoresistible (build 8) | TH_2033 | fadB | 5e-12 | 28.21% (195) | PROBABLE FATTY OXIDATION PROTEIN FADB |
| M. thermoresistible (build 8) | TH_3655 | - | 7e-11 | 28.43% (197) | PUTATIVE short chain enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0649c | echA3 | 6e-71 | 59.13% (230) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_5125 | - | 6e-95 | 74.25% (233) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0632c | echA3 | 6e-71 | 59.13% (230) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02161 | fadB | 2e-08 | 27.08% (192) | putative fatty oxidation complex alpha subunit |
| M. abscessus ATCC 19977 | MAB_3124 | - | 7e-10 | 30.57% (193) | enoyl-CoA hydratase |
| M. marinum M | MMAR_0962 | echA3 | 4e-68 | 57.39% (230) | enoyl-CoA hydratase, EchA3 |
| M. avium 104 | MAV_4534 | - | 4e-70 | 59.57% (230) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_1331 | - | 1e-86 | 70.09% (234) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0713 | echA3 | 3e-68 | 57.39% (230) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1226 | - | 3e-91 | 71.67% (233) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5125|M.gilvum_PYR-GCK -MTGTVSYDLADS-VATVTLDDGKVN--VLGPAMQAAINNALDR----AE
Mvan_1226|M.vanbaalenii_PYR-1 -MTSTVSYEFADS-VATISLDDGKVN--VLGPAMQAAINEALDR----AE
MSMEG_1331|M.smegmatis_MC2_155 -MSSLVSYALNGN-VATVTLDDGKAN--ALSPDMQAAINDALDQASLAAG
TH_1874|M.thermoresistible__bu -MSSTVEYQLTDS-VATITMDDGKVN--VLSPAMQGNLNEALDR----AE
Mb0649c|M.bovis_AF2122/97 -MSDPVSYTRKDS-IAVISMDDGKVN--ALGPAMQQALNAAIDN----AD
Rv0632c|M.tuberculosis_H37Rv -MSDPVSYTRKDS-IAVISMDDGKVN--ALGPAMQQALNAAIDN----AD
MAV_4534|M.avium_104 -MSGPVHYSTKGP-VAVIRMDDGKVN--ALGPTMQQALGEAIDR----AE
MMAR_0962|M.marinum_M -MSGPVTYTHDDA-IGVIRMDDGKVN--VLGPTMQQALNEAIDA----AD
MUL_0713|M.ulcerans_Agy99 -MSGPVTYTHDDA-IGVIRMDDGKVN--VLGPTMQQALNEAIDA----AD
MAB_3124|M.abscessus_ATCC_1997 -MTEPILLTHTEDRICTITLNRPQARN-ALSTALGEEIVKAVTA----AD
MLBr_02161|M.leprae_Br4923 MADTAIQWSKDADGIVTLTMNDPSRSANVMNEIYIESMGNAVDR--IVAE
: : .: :: . .:. : *: *
Mflv_5125|M.gilvum_PYR-GCK ADK-AKAVVLAGNSRVFSGGFDLGVFQ---SGDAAAALGMLSGGFELSVR
Mvan_1226|M.vanbaalenii_PYR-1 ADK-AKAVVLAGNSRVFSGGFDLSVFQ---SGDAAAALGMLAGGFELSLR
MSMEG_1331|M.smegmatis_MC2_155 SGE-VKALVVAGNSKVFSGGFDLSVFA---SGDAAAALGMLTGGFELAVR
TH_1874|M.thermoresistible__bu QDG-AKAVVLAGNSRVFSGGFDLSVFS---SGDVDAALGMLRGGFELAVR
Mb0649c|M.bovis_AF2122/97 RDD-VGALVITGNGRVFSGGFDLKILT---SGEVQPAIDMLRGGFELAYR
Rv0632c|M.tuberculosis_H37Rv RDD-VGALVITGNGRVFSGGFDLKILT---SGEVQPAIDMLRGGFELAYR
MAV_4534|M.avium_104 ADN-AGALVITGNERVFSGGFDLKILT---SGEVQPAVNMLRGGFELAYR
MMAR_0962|M.marinum_M RDN-VGALVIAGNHRVFSGGFDLKVLT---SGEAKPAIDMLRGGFELSYR
MUL_0713|M.ulcerans_Agy99 RDN-VGALVIAGNHRVFSGGFDLKVLT---SGEAKPAIDMLRGGFELSYR
MAB_3124|M.abscessus_ATCC_1997 ADENVDVMILTAADPVFCAGVDLKELG---SGDRAESLDPWWP-------
MLBr_02161|M.leprae_Br4923 KDS-ITGVVITSAKRTFFAGGDLTAMINTGSEEAGQCFDTVETVKKQLRT
. ::::. .* .* ** : * : ...
Mflv_5125|M.gilvum_PYR-GCK TLTFPVPVIIAATGPAIAMGSFLLLSGDHRVGQPK--TRCQAIEVAIGMT
Mvan_1226|M.vanbaalenii_PYR-1 TLTFPAPVIVAATGPAIAMGSFLLLSTDHRVGQPK--SRCQAIEVAIGMT
MSMEG_1331|M.smegmatis_MC2_155 CLTFPVPVIMAATGPAIAMGSFLLLSGDHRVGSPR--SRCQANEVAIGMT
TH_1874|M.thermoresistible__bu ALTFPVPVIMAATGPAIAMGSFLLLCGDHRVGSER--TRCQANEVAIGMI
Mb0649c|M.bovis_AF2122/97 LLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHA--YNIQANEVAIGMT
Rv0632c|M.tuberculosis_H37Rv LLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHA--YNIQANEVAIGMT
MAV_4534|M.avium_104 LLSYPKPVVMACTGHAIAMGAFLLSSGDHRVAAHA--YNIQANEVAIGMV
MMAR_0962|M.marinum_M LLSYPKPVVIACTGHAIAMGAFLLCSGDHRVAAHA--YNVQANEVAIGMT
MUL_0713|M.ulcerans_Agy99 LLSYPKPVVIACTGHAIAMGAFLLCSGDHRVAAHA--YNIQANEVAIGMT
MAB_3124|M.abscessus_ATCC_1997 --ELSKPVIGAINGAAVTGGLELALACDILIASEK--ARFADTHARVGIL
MLBr_02161|M.leprae_Br4923 LETLGKPVVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLL
**: * .* *: * : . . :. . .. :*:
Mflv_5125|M.gilvum_PYR-GCK IP-IAALEIMRARLTPAAFERSAALASTYVGDDAVAAGWLDEIVEADQVL
Mvan_1226|M.vanbaalenii_PYR-1 IP-ISALEIMRMRLTPAAFERGAALAATFAGDDAVAGGWLDEIVPADQVL
MSMEG_1331|M.smegmatis_MC2_155 LP-IAAIEIMRMRLTRAAFQRAISMAAVFSGDAAISAGWLDEIVEPDEVL
TH_1874|M.thermoresistible__bu LP-VAALEIMRMRLTPAAYQHAVSLATTFTGDAAIRAGWLDEVVDTDRVL
Mb0649c|M.bovis_AF2122/97 IP-YAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVV
Rv0632c|M.tuberculosis_H37Rv IP-YAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVV
MAV_4534|M.avium_104 IP-YAAMEIMKLRLTPSAYQQASGLAKTFFGETALAAGFVDEIVLPEVVV
MMAR_0962|M.marinum_M IP-YAAMEVLKLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVL
MUL_0713|M.ulcerans_Agy99 IP-YAAMEVLKLRLTPSAYQQAAGLAKTFFGETALAAGFIDEISLPEVVL
MAB_3124|M.abscessus_ATCC_1997 PT-WGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAHNELL
MLBr_02161|M.leprae_Br4923 PGGGGVTRTVRMFGIQNAFVNILSQGTRFKPAKAKEIGLVDELLSTVEEL
. : . . * * : *: :
Mflv_5125|M.gilvum_PYR-GCK TRAQQVAAEAATT-----------------------------LHAGAHLA
Mvan_1226|M.vanbaalenii_PYR-1 ARAQQVAGEAAAT-----------------------------LHPGAHLA
MSMEG_1331|M.smegmatis_MC2_155 DRAQQVATEAAA------------------------------LHTNAHVA
TH_1874|M.thermoresistible__bu PRAREFAAEVATT-----------------------------VHAHAHLA
Mb0649c|M.bovis_AF2122/97 SRAEEAAREFAG------------------------------LNQHAHAA
Rv0632c|M.tuberculosis_H37Rv SRAEEAAREFAG------------------------------LNQHAHAA
MAV_4534|M.avium_104 DRAEEAAAEFAE------------------------------LNQRAHAA
MMAR_0962|M.marinum_M SRAEEAAREFAG------------------------------LNQQAHNA
MUL_0713|M.ulcerans_Agy99 SRAEEAAREFAG------------------------------LNQQAHNA
MAB_3124|M.abscessus_ATCC_1997 PAAKRLAATIAGNNQPAVRELLASYRR----------IESELVGNGLQVA
MLBr_02161|M.leprae_Br4923 VPAAKAWIKANPEAHEQPWDKKSYEMPGGTPTSPGLAAILPSFPSLLRKQ
* . . :
Mflv_5125|M.gilvum_PYR-GCK TKLKARKYALDAIRAGIDGLATEFTLG-----------------------
Mvan_1226|M.vanbaalenii_PYR-1 TKLKARKPALDAIRAGIDGLATEFSLG-----------------------
MSMEG_1331|M.smegmatis_MC2_155 SKLKARADAVTAIRAGIDGLAAEFGS------------------------
TH_1874|M.thermoresistible__bu SKLKARDAALKAIRAGIDGIATEFTGG-----------------------
Mb0649c|M.bovis_AF2122/97 TKLRSRADALTAIRAGIDGIAAEFGL------------------------
Rv0632c|M.tuberculosis_H37Rv TKLRSRADALTAIRAGIDGIAAEFGL------------------------
MAV_4534|M.avium_104 TKLRARADALAAIRAGIDGIEAEFGL------------------------
MMAR_0962|M.marinum_M TKLRARAEALKAIRAGIDGIEAEFGL------------------------
MUL_0713|M.ulcerans_Agy99 TKLRARAEALKAIRAGIDGIEAEFGL------------------------
MAB_3124|M.abscessus_ATCC_1997 LDDAHRWIDQNSIAEGVEARRTAIMERGRSQNA-----------------
MLBr_02161|M.leprae_Br4923 LKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFVSLVTGQVAKNMIQA
. : .::. . :
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 FFLDLQHINSGGSRPDGIGKTPIKKIGVLGAGMMGAGIAYVSAKAGYNVV
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 LKDVSLEAAQKGKSYSEKLEAKALERGRTTQEKSDVLLACIAPTGDPTDL
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 KGVDFVIEAVFENQELKHKVFQEIEDIVDPNAVLGSNTSTLPITGLATGV
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 KRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDEALARVFDYALAIGKTPIV
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 VNDSRGFFTSRVIGTFVNEALAMLGEGVEPSSIEQAGAQAGYPAPPLQLS
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 DELNLELMHKIAIATRKGVEDAGGMYESHPAETVVEKMIKLGRSGRLKGA
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 GFYEYVDGKRSGLWLGLRETFKSGSSQPPLQDMIDRMLFAEALETQKCLD
Mflv_5125|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1226|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1331|M.smegmatis_MC2_155 --------------------------------------------------
TH_1874|M.thermoresistible__bu --------------------------------------------------
Mb0649c|M.bovis_AF2122/97 --------------------------------------------------
Rv0632c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4534|M.avium_104 --------------------------------------------------
MMAR_0962|M.marinum_M --------------------------------------------------
MUL_0713|M.ulcerans_Agy99 --------------------------------------------------
MAB_3124|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02161|M.leprae_Br4923 ENVLTSTADANIGSIMGIGFPPWTGGSAQFIAGYSGPAGTGQQAFVSRAR
Mflv_5125|M.gilvum_PYR-GCK -----------------
Mvan_1226|M.vanbaalenii_PYR-1 -----------------
MSMEG_1331|M.smegmatis_MC2_155 -----------------
TH_1874|M.thermoresistible__bu -----------------
Mb0649c|M.bovis_AF2122/97 -----------------
Rv0632c|M.tuberculosis_H37Rv -----------------
MAV_4534|M.avium_104 -----------------
MMAR_0962|M.marinum_M -----------------
MUL_0713|M.ulcerans_Agy99 -----------------
MAB_3124|M.abscessus_ATCC_1997 -----------------
MLBr_02161|M.leprae_Br4923 ELVAKYGDRFLPPESLL