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MTIAVHYDEKIAILELGDDENRFTSVFLEEINSHLDEIIASGANGLVTTALGKFYSNGLDLDWLSAHRDQ TQWYVGKVQGLLARLLTLPIPTAAAVVGHAFGAGAMLAMAHDFRVMRADRGYFCFPEVDIRIPFTPGMAA LIQAKLAPQAATASMTTGRRFGGGEAARLGIVDNTAAEDAVTAVAVDLLHPLGGKDPGTLGVIKQTMFGH AAAALSANA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02498 | - | - | 100% (219) | putative enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01724 | - | 8e-09 | 34.34% (99) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-07 | 25.41% (181) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0649c | echA3 | 2e-09 | 27.11% (225) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2522 | - | 1e-09 | 29.55% (176) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0632c | echA3 | 2e-09 | 27.11% (225) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2465c | - | 5e-71 | 58.53% (217) | enoyl-coa hydratase/isomerase family protein |
| M. marinum M | MMAR_4691 | echA8_2 | 3e-09 | 30.59% (170) | enoyl-CoA hydratase, EchA8_2 |
| M. avium 104 | MAV_0967 | - | 3e-11 | 29.67% (182) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_6558 | - | 1e-88 | 74.42% (215) | putative enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2890 | - | 1e-14 | 31.25% (192) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0310 | echA8_2 | 6e-10 | 31.18% (170) | enoyl-CoA hydratase, EchA8_2 |
| M. vanbaalenii PYR-1 | Mvan_4851 | - | 2e-11 | 31.55% (206) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02498|M.leprae_Br4923 -----------------MTIAVHYD---EKIAILELGDDENR--FTSVFL
MSMEG_6558|M.smegmatis_MC2_155 -----------------MTATLDYD---GDIAVLDLGDDENR--FTPQFL
MAB_2465c|M.abscessus_ATCC_199 -----------------MTPTLELQ---DTIAVLNLGADENR--FSPDWL
MMAR_4691|M.marinum_M ------------------MVDLEFDELDTGLAVLTIDRPHARNAIGLETM
MUL_0310|M.ulcerans_Agy99 ------------------MVDLEFDGLDTGLAVLTIDRPHARNAIGLETM
MAV_0967|M.avium_104 ------------------MVDLEID---DGLAVLTIDRPHARNAIALDTM
Mflv_2522|M.gilvum_PYR-GCK ------------------MVDLEID---DGLAIITIDRPHARNAISLETM
Mb0649c|M.bovis_AF2122/97 -----------------MSDPVSYTR-KDSIAVISMDDGKVN-ALGPAMQ
Rv0632c|M.tuberculosis_H37Rv -----------------MSDPVSYTR-KDSIAVISMDDGKVN-ALGPAMQ
TH_2890|M.thermoresistible__bu ---------------VTADAPLVLREDRGAVALLWLNRAAQRNALRYESW
Mvan_4851|M.vanbaalenii_PYR-1 MGVPPACGGRSREEATVLMSTLVTYERDGAVARLTLDSPHNRNALSTALV
: :* : :. . :
MLBr_02498|M.leprae_Br4923 EEINSHLDEIIASG-ANGLVTTALGKFYSNG-LDLDWLSAHRDQT--QWY
MSMEG_6558|M.smegmatis_MC2_155 DEVDALLDAVLEKG-AHGLVTTADSKFYSNG-LDLEWLGAHSDQG--AWY
MAB_2465c|M.abscessus_ATCC_199 ETVDGLLDDVLTQ--AQALVTVGTGKFYSNG-LDLDWLMSHGDRT--DWY
MMAR_4691|M.marinum_M AQLQDALDAAAGAQ-ALVIKGAGDRAFVSGGDLKELSALRTLEDA--SAM
MUL_0310|M.ulcerans_Agy99 AQLQDALDAAAGAQ-ALVIKGAGDRAFVSGGDLKELSALRTLEDA--SAM
MAV_0967|M.avium_104 DQLEKALDAAAGAQ-ALVITGAGDRAFVSGGDLKELSALRTEEDA--AAM
Mflv_2522|M.gilvum_PYR-GCK DQLDTALDGAHGAR-ALALTGAGDKAFVSGGDLKELSALRTVEQA--ASM
Mb0649c|M.bovis_AF2122/97 QALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKILTSGEVQPA--IDM
Rv0632c|M.tuberculosis_H37Rv QALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKILTSGEVQPA--IDM
TH_2890|M.thermoresistible__bu TELSEHLAVLAEDPDVRGVXVAGAGGFFSAGGDLKTGPAHGAGPLGPAGR
Mvan_4851|M.vanbaalenii_PYR-1 EQLHDGLTRASSEPRVRTVVLGHTGRTFCAGADLSEAAGRDPSDLA-VDR
: : . : . *
MLBr_02498|M.leprae_Br4923 VGKVQGLLARLLTLPIPTAAAVVGHAFGAGAMLAMAHDFRVMRADRGYFC
MSMEG_6558|M.smegmatis_MC2_155 VGRVQGLLARVLTFPLPTAAAVVGHAFGAGAMLAMAHDYRVMREDRGFFC
MAB_2465c|M.abscessus_ATCC_199 VGRVHALFRRVLTFGLPTVAAINGHAFGAGAMLAVAHDYRVMRSDRGFLC
MMAR_4691|M.marinum_M AKRMRSICDQIAAFPAPVIAALNGHAFGGGAEVAVAADIRVAADD-IKIA
MUL_0310|M.ulcerans_Agy99 AKRMRSICDQIATFPAPVIAALNGHAFGGGAEVAVAADIRVAADD-IKIA
MAV_0967|M.avium_104 ARRMRAICDQLADFPAPVVAALNGHAFGGGAEVAVAADIRVAADD-IKIA
Mflv_2522|M.gilvum_PYR-GCK SFRMRSICDRIAGFPAPVVAALNGHALGGGAEFAVAADIRLAADD-IKIG
Mb0649c|M.bovis_AF2122/97 LRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHA-YNIQ
Rv0632c|M.tuberculosis_H37Rv LRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHA-YNIQ
TH_2890|M.thermoresistible__bu VEHAQRVMEQLKAVPVPTVAAVEGAAVGLGWSLALACDLVVAASD-AFFS
Mvan_4851|M.vanbaalenii_PYR-1 AREMTRLLRRILELPLPVIAAVDGHVRAGGLGLVGACDIAVAGDS-STFA
: :: *. * * . . * . . * : :
MLBr_02498|M.leprae_Br4923 FPEVDIRIPFTPGMAALIQAKLAPQAATASMTTGRRFGGGEAARLGIVDN
MSMEG_6558|M.smegmatis_MC2_155 FPEVDIHIPFTPGMAALIQAKLTPQAAIASMTTGRRFGGSEAHEHGIVDA
MAB_2465c|M.abscessus_ATCC_199 FPEVDIHIPFTPGMASLIQAKVGPQTAVTAMTTGHRYGGAAAVAAGLADS
MMAR_4691|M.marinum_M FNQVLLEIMPAWGGAERLAAVVGKSKALLLAGSGIALDAVEAERIGLVDL
MUL_0310|M.ulcerans_Agy99 FNQVLLEIMPAWGGAERLAAVVGKSKALLLAGSGIALDAVEAERIGLVDL
MAV_0967|M.avium_104 FNQVALEIMPAWGGAERLAALVGQSRALLLAGSGTALDAVEAERIGLVDR
Mflv_2522|M.gilvum_PYR-GCK FNQVALEIMPAWGGAERLVELVGYSRALLLAGTGRILAATDAERLGLIDQ
Mb0649c|M.bovis_AF2122/97 ANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDE
Rv0632c|M.tuberculosis_H37Rv ANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDE
TH_2890|M.thermoresistible__bu APFVARAVVPDGGLAWRLTHQLGRQRASALLLRGSRLAAPDAAQAGLVTE
Mvan_4851|M.vanbaalenii_PYR-1 LTEARIGVAPS-IISLTLLPKMTARAAGRYFVTGEKFGAAEAAAMGLVT-
. : : : . . * *:
MLBr_02498|M.leprae_Br4923 TAAEDAVTAVAVDLLHPLGGKDPGTLGVIKQTMFGHAAAALSANA-----
MSMEG_6558|M.smegmatis_MC2_155 TAHEGAVTLAATSLLRPLGSKDQGTLGAIKQVMFGAAAAALRNP------
MAB_2465c|M.abscessus_ATCC_199 CAAEHEVLSTAIDLMKPLTGKDSGTLSAIKATMFAATATALAA-------
MMAR_4691|M.marinum_M VFPRASFDSTDGGWRSLARSLARRPAAEVKRVINGTSPDEAIASFARLWV
MUL_0310|M.ulcerans_Agy99 VFPRASFDSTDGGWRSLARSLARRPAAEVKRVINGTSPDEAIASFARLWV
MAV_0967|M.avium_104 VLPRDVFDSAEQGWRSIARSLARRPAAEIKRVIRGVSPEEAIASFARLWV
Mflv_2522|M.gilvum_PYR-GCK VIPRASFD---EQWRLTARLLASVPAGEVKRVMRGVPTTEAVAAFARLWV
Mb0649c|M.bovis_AF2122/97 IALPEVVVSRAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAA
Rv0632c|M.tuberculosis_H37Rv IALPEVVVSRAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAA
TH_2890|M.thermoresistible__bu LAELGSAVEVALALLDELASADAGAVEMTKRLINSVEAAQLAAFHPLELA
Mvan_4851|M.vanbaalenii_PYR-1 -VATDDVPGTVADLTSAIAQGSPQGLAASKALTTAALIDDFERRAEKLTQ
* .
MLBr_02498|M.leprae_Br4923 ----------------------------
MSMEG_6558|M.smegmatis_MC2_155 ----------------------------
MAB_2465c|M.abscessus_ATCC_199 ----------------------------
MMAR_4691|M.marinum_M EDAHWQAAERVMNRTPNRGPGAEGAT--
MUL_0310|M.ulcerans_Agy99 EDAHWQAAEQVMNRTPNRGPGAEGAT--
MAV_0967|M.avium_104 ADPHWQAAERVMARNTKPRPAAGGAS--
Mflv_2522|M.gilvum_PYR-GCK SDEHWAAADKVMKKGK------------
Mb0649c|M.bovis_AF2122/97 EFGL------------------------
Rv0632c|M.tuberculosis_H37Rv EFGL------------------------
TH_2890|M.thermoresistible__bu MATVAQQRSASAAARDRW----------
Mvan_4851|M.vanbaalenii_PYR-1 ESARLFVSEEAREGMLAFLEKRPPRWVG