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MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWMTDTSGRQYLDFFAGAGALNYG HNNPVLKAPLIDYLSQDSIVHSLDMATAAKTEFLETFERLILRPRSLDYKVQFPGPTGANAVESALKLAR KVTGRESIINFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYDNYFGGITEDFHWFERVLDDSGG GLNHPAAVIVETVQGEGGLNVARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVT LSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALETYWKSATFAENTAAKGQHVRDR LESIAAAHEGISARGRGMAQGLKCEEKDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDLDAG LDILAEAVATTVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4833 | - | - | 100% (433) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. gilvum PYR-GCK | Mflv_5071 | - | 4e-40 | 29.64% (415) | ornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_3818 | - | 2e-35 | 29.85% (412) | 4-aminobutyrate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 9e-38 | 32.73% (385) | acetylornithine aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 9e-38 | 32.73% (385) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 6e-37 | 29.61% (412) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_2266c | - | 0.0 | 71.77% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. marinum M | MMAR_0166 | gabT_2 | 6e-54 | 33.49% (424) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. avium 104 | MAV_2086 | rocD | 1e-37 | 28.92% (408) | ornithine--oxo-acid transaminase |
| M. smegmatis MC2 155 | MSMEG_3900 | ectB | 0.0 | 78.95% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 0.0 | 81.77% (417) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_4930 | gabT_2 | 2e-54 | 33.49% (424) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. vanbaalenii PYR-1 | Mvan_5273 | - | 0.0 | 83.14% (427) | diaminobutyrate--2-oxoglutarate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4833|M.gilvum_PYR-GCK -MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWM
Mvan_5273|M.vanbaalenii_PYR-1 -----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWV
MSMEG_3900|M.smegmatis_MC2_155 ------MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWV
TH_3246|M.thermoresistible__bu --------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWI
MAB_2266c|M.abscessus_ATCC_199 --------MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWL
MMAR_0166|M.marinum_M --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
MUL_4930|M.ulcerans_Agy99 --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
Mb1683|M.bovis_AF2122/97 ----------MTGASTTT--ATMRQRWQAVMMNNYGTPPIALASGDGAVV
Rv1655|M.tuberculosis_H37Rv ----------MTGASTTT--ATMRQRWQAVMMNNYGTPPIALASGDGAVV
MAV_2086|M.avium_104 -------MTILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWI
MLBr_00485|M.leprae_Br4923 MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAAGGVI
* . . :
Mflv_4833|M.gilvum_PYR-GCK TDTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAA
Mvan_5273|M.vanbaalenii_PYR-1 TDVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEA
MSMEG_3900|M.smegmatis_MC2_155 TDVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTA
TH_3246|M.thermoresistible__bu TDVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAA
MAB_2266c|M.abscessus_ATCC_199 TDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDGVVHGLDMATVA
MMAR_0166|M.marinum_M RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPA
MUL_4930|M.ulcerans_Agy99 RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPA
Mb1683|M.bovis_AF2122/97 TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYAT-EP
Rv1655|M.tuberculosis_H37Rv TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYAT-EP
MAV_2086|M.avium_104 TDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDTVTLVSRAVHS-DK
MLBr_00485|M.leprae_Br4923 EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEE
* .*. :* .. .. * * : . :
Mflv_4833|M.gilvum_PYR-GCK KTEFLETFERLILRPRSLDYKVQFPGPTGANAVESALKLAR--------K
Mvan_5273|M.vanbaalenii_PYR-1 KTRFLETFERLILRPRGLDYKVQFPGPTGANTVEAALKLAR--------K
MSMEG_3900|M.smegmatis_MC2_155 KQRFLETFQRAILQPRNLDYKVQFPGPTGANAVESALKLAR--------K
TH_3246|M.thermoresistible__bu KQEFLETFSELILKPRGLDYKVQFPGPTGANAVESALKLAR--------K
MAB_2266c|M.abscessus_ATCC_199 KQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLAR--------N
MMAR_0166|M.marinum_M REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAE--------I
MUL_4930|M.ulcerans_Agy99 REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAE--------I
Mb1683|M.bovis_AF2122/97 GIALAEELVALLG---ADQRTRVFFCNSGAEANEAAFKLSR---------
Rv1655|M.tuberculosis_H37Rv GIALAEELVALLG---ADQRTRVFFCNSGAEANEAAFKLSR---------
MAV_2086|M.avium_104 LGPFCAALAYLCD---KDM---VLPMNSGAEAVESGLKVARKWGAEVKGV
MLBr_00485|M.leprae_Br4923 YVAVTEQLNRITP---GSGEKRSVLFNSGAEAVENSIKVAR--------S
. : . :*:.: * .:.::.
Mflv_4833|M.gilvum_PYR-GCK VTGRESIINFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
Mvan_5273|M.vanbaalenii_PYR-1 VTGRESIISFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
MSMEG_3900|M.smegmatis_MC2_155 VTGRESVISFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
TH_3246|M.thermoresistible__bu VTGRESIVSFTNAFHGMTLGALSVTGNSMKRAG-AGVPLVHSTPMPYDNY
MAB_2266c|M.abscessus_ATCC_199 ITGRESIISFTNAFHGMTLGSLAVTGNSMKRAG-AGVPLVHSTPMPYDNY
MMAR_0166|M.marinum_M ATGGREHVGVQGGFHGCTRAARAASSGGGLRQQ-PVVMAPRTTFLPFPQN
MUL_4930|M.ulcerans_Agy99 ATGGREHVGVQGGFHGCTRAARAASSGGGLRQQ-PVVMAPRTTFLPFPQN
Mb1683|M.bovis_AF2122/97 LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG--
Rv1655|M.tuberculosis_H37Rv LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG--
MAV_2086|M.avium_104 PAGQANIIVADNNFHGRTISIVSFSSDAAARDG-FGPFTPGFRSVPFG--
MLBr_00485|M.leprae_Br4923 YTRKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYP
: : :** * : :.
Mflv_4833|M.gilvum_PYR-GCK FGG--------ITEDFHWFERVLD-DSGGGLNHPAAVIVETVQGEGGLNV
Mvan_5273|M.vanbaalenii_PYR-1 FGG--------VTEDFHWFERVLD-DSGSGLNRPAAVIVETVQGEGGLNV
MSMEG_3900|M.smegmatis_MC2_155 FDG--------VTEDFQWFGRVLD-DSGSGLNRPAAVIVETVQGEGGLNV
TH_3246|M.thermoresistible__bu FGG--------VTEDFQWFEKVLD-DEGSGLNRPAAVIVETVQGEGGLNV
MAB_2266c|M.abscessus_ATCC_199 FGG--------VTEDFQWFEKVLD-DEGGGLNKPAAVIVETVQGEGGVNV
MMAR_0166|M.marinum_M YRCPFGVGGERGVDLAVTAVEQLA-APHAGISAPASIISEFVLGEGGVLP
MUL_4930|M.ulcerans_Agy99 YRCPFGVGGERGVDLAVTAVEQLA-APHAGISAPASIISEFVLGEGGVLP
Mb1683|M.bovis_AF2122/97 -----------DVDALA----------AAVDDHTAAVFLEPIMGESGVVV
Rv1655|M.tuberculosis_H37Rv -----------DVDALA----------AAVDDHTAAVFLEPIMGESGVVV
MAV_2086|M.avium_104 -----------DAGALA----------QAIDDNTVAVLLEPIQGEAGIVV
MLBr_00485|M.leprae_Br4923 YRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIV
. .::: * : **.*.
Mflv_4833|M.gilvum_PYR-GCK ARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTL
Mvan_5273|M.vanbaalenii_PYR-1 ARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIVTL
MSMEG_3900|M.smegmatis_MC2_155 ARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIVTL
TH_3246|M.thermoresistible__bu ARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIVTL
MAB_2266c|M.abscessus_ATCC_199 ARAEWLQALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTL
MMAR_0166|M.marinum_M AHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVVM
MUL_4930|M.ulcerans_Agy99 AHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVVM
Mb1683|M.bovis_AF2122/97 PPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTL
Rv1655|M.tuberculosis_H37Rv PPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTL
MAV_2086|M.avium_104 PPDDYLPAVRALCSEHNVLMIADEIQSGLARTGYTFACDRWRVVPDVYLL
MLBr_00485|M.leprae_Br4923 PAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDGIVPDLICT
. : :: *::* * *** :. : : **:
Mflv_4833|M.gilvum_PYR-GCK SKSISGYGLPMALTLFR-RDLDVWAPGEHNGTFRGHNPAFVTATKALETY
Mvan_5273|M.vanbaalenii_PYR-1 SKSISGYGLPMALTLFR-RQLDVWTPGEHNGTFRGHNPAFVTAAKALETY
MSMEG_3900|M.smegmatis_MC2_155 SKSVSGYGLPMALTLFR-RDLDVWAPGEHNGTFRGHNPAFVTATQALQTY
TH_3246|M.thermoresistible__bu SKSISGYGLPMALTLFR-RELDVWAPGEHNGTFRGHNPAFVTATAALKTY
MAB_2266c|M.abscessus_ATCC_199 SKSISGYGLPMALTLIR-PDLDQWTPGEHNGTFRGNNPAFVTATATLQKY
MMAR_0166|M.marinum_M SKGLG-SGVPIAVIVVR-EGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
MUL_4930|M.ulcerans_Agy99 SKGLG-SGVPIAVIVVR-EGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
Mb1683|M.bovis_AF2122/97 AKGLGGG-LPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
Rv1655|M.tuberculosis_H37Rv AKGLGGG-LPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
MAV_2086|M.avium_104 GKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPLAAAIGTTVVSML
MLBr_00485|M.leprae_Br4923 AKGIADG-LPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTI
.*.:. :*:. . .** *: . . . .:
Mflv_4833|M.gilvum_PYR-GCK WKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE---
Mvan_5273|M.vanbaalenii_PYR-1 WETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED---
MSMEG_3900|M.smegmatis_MC2_155 WQDDKFSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD---
TH_3246|M.thermoresistible__bu WQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ---
MAB_2266c|M.abscessus_ATCC_199 WQDNTFSDDVRRKGDRLHDELTALVADDDSVS-IRGRGMVQGIAFAD---
MMAR_0166|M.marinum_M AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
MUL_4930|M.ulcerans_Agy99 AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
Mb1683|M.bovis_AF2122/97 ASDG-LVRRAEVLGKSLRHGIEALGHP--LIDHVRGRGLLLGIALTAP--
Rv1655|M.tuberculosis_H37Rv ASDG-LVRRAEVLGKSLRHGIEALGHP--LIDHVRGRGLLLGIALTAP--
MAV_2086|M.avium_104 ARGE-YQARATALGAHLQRRLRALVGH--GVDEVRGLGLWAGVDIDPS--
MLBr_00485|M.leprae_Br4923 ENDG-LIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGT
. . : : : ** * .
Mflv_4833|M.gilvum_PYR-GCK ---------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDL
Mvan_5273|M.vanbaalenii_PYR-1 ---------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDL
MSMEG_3900|M.smegmatis_MC2_155 ---------TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDL
TH_3246|M.thermoresistible__bu ---------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQEEL
MAB_2266c|M.abscessus_ATCC_199 ---------AERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQL
MMAR_0166|M.marinum_M PWPSGVAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
MUL_4930|M.ulcerans_Agy99 PWPSGVAPAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
Mb1683|M.bovis_AF2122/97 -----------HAKDAEATAR--DAGYLVNAAAPDVIRLAPPLIIAEAQL
Rv1655|M.tuberculosis_H37Rv -----------HAKDAEATAR--DAGYLVNAAAPDVIRLAPPLIIAEAQL
MAV_2086|M.avium_104 -----------LGSGRQMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEI
MLBr_00485|M.leprae_Br4923 -----AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELL
: ::: *.* :
Mflv_4833|M.gilvum_PYR-GCK DAGLDILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1 DSGIDILAEAIAVTVA-------------
MSMEG_3900|M.smegmatis_MC2_155 EAGLDILAESIAVTLS-------------
TH_3246|M.thermoresistible__bu EAGLGILADAVAATVD-------------
MAB_2266c|M.abscessus_ATCC_199 DIGIATLREAITESAQ-------------
MMAR_0166|M.marinum_M SAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99 SAALTAFEAAVKQVERHRTKAVDLRADQR
Mb1683|M.bovis_AF2122/97 DGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv DGFVAALPAILDRAVGAP-----------
MAV_2086|M.avium_104 DWAVGQLAAVLREAAS-------------
MLBr_00485|M.leprae_Br4923 AEGLDILSRILGDF---------------
: : :