For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3246 (ectB)

annotation: diaminobutyrate--2-oxoglutarate aminotransferase
coordinates: 3277475 - 3278755
length: 427

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3246ectB-100% (427)diaminobutyrate--2-oxoglutarate aminotransferase
M. thermoresistible (build 8)TH_3529-1e-3932.57% (393) PUTATIVE aminotransferase
M. thermoresistible (build 8)TH_1978-9e-2728.54% (424) PROBABLE AMINOTRANSFERASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1683argD2e-3931.79% (390) acetylornithine aminotransferase
M. gilvum PYR-GCKMflv_4833-0.081.77% (417) diaminobutyrate--2-oxoglutarate aminotransferase
M. tuberculosis H37RvRv1655argD2e-3931.79% (390) acetylornithine aminotransferase
M. leprae Br4923MLBr_00485gabT2e-3829.41% (408) 4-aminobutyrate aminotransferase
M. abscessus ATCC 19977MAB_2266c-0.072.68% (421) diaminobutyrate--2-oxoglutarate aminotransferase
M. marinum MMMAR_0166gabT_22e-5533.73% (424) 4-aminobutyrate aminotransferase, GabT_2
M. avium 104MAV_2086rocD2e-3729.68% (401) ornithine--oxo-acid transaminase
M. smegmatis MC2 155MSMEG_3900ectB0.082.19% (421) diaminobutyrate--2-oxoglutarate aminotransferase
M. ulcerans Agy99MUL_4930gabT_22e-5533.73% (424) 4-aminobutyrate aminotransferase, GabT_2
M. vanbaalenii PYR-1Mvan_5273-0.079.62% (417) diaminobutyrate--2-oxoglutarate aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3246|M.thermoresistible__bu      --------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWI
MSMEG_3900|M.smegmatis_MC2_155      ------MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWV
Mflv_4833|M.gilvum_PYR-GCK          -MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWM
Mvan_5273|M.vanbaalenii_PYR-1       -----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWV
MAB_2266c|M.abscessus_ATCC_199      --------MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWL
MMAR_0166|M.marinum_M               --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
MUL_4930|M.ulcerans_Agy99           --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
Mb1683|M.bovis_AF2122/97            ----------MTGASTTT--ATMRQRWQAVMMNNYGTPPIALASGDGAVV
Rv1655|M.tuberculosis_H37Rv         ----------MTGASTTT--ATMRQRWQAVMMNNYGTPPIALASGDGAVV
MAV_2086|M.avium_104                -------MTILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWI
MLBr_00485|M.leprae_Br4923          MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAAGGVI
                                                                          *     . .  :

TH_3246|M.thermoresistible__bu      TDVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAA
MSMEG_3900|M.smegmatis_MC2_155      TDVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTA
Mflv_4833|M.gilvum_PYR-GCK          TDTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAA
Mvan_5273|M.vanbaalenii_PYR-1       TDVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEA
MAB_2266c|M.abscessus_ATCC_199      TDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDGVVHGLDMATVA
MMAR_0166|M.marinum_M               RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPA
MUL_4930|M.ulcerans_Agy99           RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPA
Mb1683|M.bovis_AF2122/97            TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYAT-EP
Rv1655|M.tuberculosis_H37Rv         TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYAT-EP
MAV_2086|M.avium_104                TDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDTVTLVSRAVHS-DK
MLBr_00485|M.leprae_Br4923          EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEE
                                     * .*.  :*  .. ..   *   * :  .    :               

TH_3246|M.thermoresistible__bu      KQEFLETFSELILKPRGLDYKVQFPGPTGANAVESALKLAR--------K
MSMEG_3900|M.smegmatis_MC2_155      KQRFLETFQRAILQPRNLDYKVQFPGPTGANAVESALKLAR--------K
Mflv_4833|M.gilvum_PYR-GCK          KTEFLETFERLILRPRSLDYKVQFPGPTGANAVESALKLAR--------K
Mvan_5273|M.vanbaalenii_PYR-1       KTRFLETFERLILRPRGLDYKVQFPGPTGANTVEAALKLAR--------K
MAB_2266c|M.abscessus_ATCC_199      KQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLAR--------N
MMAR_0166|M.marinum_M               REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAE--------I
MUL_4930|M.ulcerans_Agy99           REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAE--------I
Mb1683|M.bovis_AF2122/97            GIALAEELVALLG---ADQRTRVFFCNSGAEANEAAFKLSR---------
Rv1655|M.tuberculosis_H37Rv         GIALAEELVALLG---ADQRTRVFFCNSGAEANEAAFKLSR---------
MAV_2086|M.avium_104                LGPFCAALAYLCD---KDM---VLPMNSGAEAVESGLKVARKWGAEVKGV
MLBr_00485|M.leprae_Br4923          YVAVTEQLNRITP---GSGEKRSVLFNSGAEAVENSIKVAR--------S
                                       .   :               .   :*:.: * .:.::.         

TH_3246|M.thermoresistible__bu      VTGRESIVSFTNAFHGMTLGALSVTGNSMKRAG-AGVPLVHSTPMPYDNY
MSMEG_3900|M.smegmatis_MC2_155      VTGRESVISFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
Mflv_4833|M.gilvum_PYR-GCK          VTGRESIINFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
Mvan_5273|M.vanbaalenii_PYR-1       VTGRESIISFTNAFHGMTLGALSVTGNSMKRAG-AGIPLVHATPMPYDNY
MAB_2266c|M.abscessus_ATCC_199      ITGRESIISFTNAFHGMTLGSLAVTGNSMKRAG-AGVPLVHSTPMPYDNY
MMAR_0166|M.marinum_M               ATGGREHVGVQGGFHGCTRAARAASSGGGLRQQ-PVVMAPRTTFLPFPQN
MUL_4930|M.ulcerans_Agy99           ATGGREHVGVQGGFHGCTRAARAASSGGGLRQQ-PVVMAPRTTFLPFPQN
Mb1683|M.bovis_AF2122/97            LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG--
Rv1655|M.tuberculosis_H37Rv         LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG--
MAV_2086|M.avium_104                PAGQANIIVADNNFHGRTISIVSFSSDAAARDG-FGPFTPGFRSVPFG--
MLBr_00485|M.leprae_Br4923          YTRKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYP
                                     :     :     :** *    : :.                        

TH_3246|M.thermoresistible__bu      FGG--------VTEDFQWFEKVLD-DEGSGLNRPAAVIVETVQGEGGLNV
MSMEG_3900|M.smegmatis_MC2_155      FDG--------VTEDFQWFGRVLD-DSGSGLNRPAAVIVETVQGEGGLNV
Mflv_4833|M.gilvum_PYR-GCK          FGG--------ITEDFHWFERVLD-DSGGGLNHPAAVIVETVQGEGGLNV
Mvan_5273|M.vanbaalenii_PYR-1       FGG--------VTEDFHWFERVLD-DSGSGLNRPAAVIVETVQGEGGLNV
MAB_2266c|M.abscessus_ATCC_199      FGG--------VTEDFQWFEKVLD-DEGGGLNKPAAVIVETVQGEGGVNV
MMAR_0166|M.marinum_M               YRCPFGVGGERGVDLAVTAVEQLA-APHAGISAPASIISEFVLGEGGVLP
MUL_4930|M.ulcerans_Agy99           YRCPFGVGGERGVDLAVTAVEQLA-APHAGISAPASIISEFVLGEGGVLP
Mb1683|M.bovis_AF2122/97            -----------DVDALA----------AAVDDHTAAVFLEPIMGESGVVV
Rv1655|M.tuberculosis_H37Rv         -----------DVDALA----------AAVDDHTAAVFLEPIMGESGVVV
MAV_2086|M.avium_104                -----------DAGALA----------QAIDDNTVAVLLEPIQGEAGIVV
MLBr_00485|M.leprae_Br4923          YRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIV
                                                                   .  .::: * : **.*.  

TH_3246|M.thermoresistible__bu      ARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIVTL
MSMEG_3900|M.smegmatis_MC2_155      ARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIVTL
Mflv_4833|M.gilvum_PYR-GCK          ARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTL
Mvan_5273|M.vanbaalenii_PYR-1       ARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIVTL
MAB_2266c|M.abscessus_ATCC_199      ARAEWLQALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTL
MMAR_0166|M.marinum_M               AHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVVM
MUL_4930|M.ulcerans_Agy99           AHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVVM
Mb1683|M.bovis_AF2122/97            PPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTL
Rv1655|M.tuberculosis_H37Rv         PPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTL
MAV_2086|M.avium_104                PPDDYLPAVRALCSEHNVLMIADEIQSGLARTGYTFACDRWRVVPDVYLL
MLBr_00485|M.leprae_Br4923          PAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDGIVPDLICT
                                    .   :              :: *::* *  ***  :. :   : **:   

TH_3246|M.thermoresistible__bu      SKSISGYGLPMALTLFR-RELDVWAPGEHNGTFRGHNPAFVTATAALKTY
MSMEG_3900|M.smegmatis_MC2_155      SKSVSGYGLPMALTLFR-RDLDVWAPGEHNGTFRGHNPAFVTATQALQTY
Mflv_4833|M.gilvum_PYR-GCK          SKSISGYGLPMALTLFR-RDLDVWAPGEHNGTFRGHNPAFVTATKALETY
Mvan_5273|M.vanbaalenii_PYR-1       SKSISGYGLPMALTLFR-RQLDVWTPGEHNGTFRGHNPAFVTAAKALETY
MAB_2266c|M.abscessus_ATCC_199      SKSISGYGLPMALTLIR-PDLDQWTPGEHNGTFRGNNPAFVTATATLQKY
MMAR_0166|M.marinum_M               SKGLG-SGVPIAVIVVR-EGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
MUL_4930|M.ulcerans_Agy99           SKGLG-SGVPIAVIVVR-EGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
Mb1683|M.bovis_AF2122/97            AKGLGGG-LPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
Rv1655|M.tuberculosis_H37Rv         AKGLGGG-LPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
MAV_2086|M.avium_104                GKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPLAAAIGTTVVSML
MLBr_00485|M.leprae_Br4923          AKGIADG-LPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTI
                                    .*.:.   :*:.              .   .** *:  . . .  .:   

TH_3246|M.thermoresistible__bu      WQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ---
MSMEG_3900|M.smegmatis_MC2_155      WQDDKFSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD---
Mflv_4833|M.gilvum_PYR-GCK          WKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE---
Mvan_5273|M.vanbaalenii_PYR-1       WETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED---
MAB_2266c|M.abscessus_ATCC_199      WQDNTFSDDVRRKGDRLHDELTALVADDDSVS-IRGRGMVQGIAFAD---
MMAR_0166|M.marinum_M               AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
MUL_4930|M.ulcerans_Agy99           AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
Mb1683|M.bovis_AF2122/97            ASDG-LVRRAEVLGKSLRHGIEALGHP--LIDHVRGRGLLLGIALTAP--
Rv1655|M.tuberculosis_H37Rv         ASDG-LVRRAEVLGKSLRHGIEALGHP--LIDHVRGRGLLLGIALTAP--
MAV_2086|M.avium_104                ARGE-YQARATALGAHLQRRLRALVGH--GVDEVRGLGLWAGVDIDPS--
MLBr_00485|M.leprae_Br4923          ENDG-LIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGT
                                             .      .   :  :      :   ** *   .        

TH_3246|M.thermoresistible__bu      ---------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQEEL
MSMEG_3900|M.smegmatis_MC2_155      ---------TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDL
Mflv_4833|M.gilvum_PYR-GCK          ---------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDL
Mvan_5273|M.vanbaalenii_PYR-1       ---------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDL
MAB_2266c|M.abscessus_ATCC_199      ---------AERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQL
MMAR_0166|M.marinum_M               PWPSGVAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
MUL_4930|M.ulcerans_Agy99           PWPSGVAPAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
Mb1683|M.bovis_AF2122/97            -----------HAKDAEATAR--DAGYLVNAAAPDVIRLAPPLIIAEAQL
Rv1655|M.tuberculosis_H37Rv         -----------HAKDAEATAR--DAGYLVNAAAPDVIRLAPPLIIAEAQL
MAV_2086|M.avium_104                -----------LGSGRQMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEI
MLBr_00485|M.leprae_Br4923          -----AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELL
                                                      :                 ::: *.*      :

TH_3246|M.thermoresistible__bu      EAGLGILADAVAATVD-------------
MSMEG_3900|M.smegmatis_MC2_155      EAGLDILAESIAVTLS-------------
Mflv_4833|M.gilvum_PYR-GCK          DAGLDILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1       DSGIDILAEAIAVTVA-------------
MAB_2266c|M.abscessus_ATCC_199      DIGIATLREAITESAQ-------------
MMAR_0166|M.marinum_M               SAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99           SAALTAFEAAVKQVERHRTKAVDLRADQR
Mb1683|M.bovis_AF2122/97            DGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv         DGFVAALPAILDRAVGAP-----------
MAV_2086|M.avium_104                DWAVGQLAAVLREAAS-------------
MLBr_00485|M.leprae_Br4923          AEGLDILSRILGDF---------------
                                       :  :   :