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STPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWVTDVSGRRYLDFFAGAGALNYGHNNPI LKQPLLDYLSSDMIVHSLDMATEAKTRFLETFERLILRPRGLDYKVQFPGPTGANTVEAALKLARKVTGR ESIISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYDNYFGGVTEDFHWFERVLDDSGSGLNRP AAVIVETVQGEGGLNVARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIVTLSKSI SGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALETYWETETFVEDTLAKGRRVRERLVGIA GNHPGVTARGRGMAQGLKFEDAAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDLDSGIDILA EAIAVTVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5273 | - | - | 100% (429) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_3311 | argD | 6e-43 | 33.50% (394) | acetylornithine aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_3146 | - | 2e-40 | 30.75% (387) | aminotransferase class-III |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 1e-40 | 32.99% (391) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_4833 | - | 0.0 | 82.60% (431) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 1e-40 | 32.99% (391) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 4e-38 | 31.84% (402) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_2266c | - | 1e-180 | 73.12% (413) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. marinum M | MMAR_0166 | gabT_2 | 1e-50 | 34.04% (426) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. avium 104 | MAV_3115 | argD | 3e-40 | 33.08% (402) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3900 | ectB | 0.0 | 80.86% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 0.0 | 79.62% (417) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_4930 | gabT_2 | 2e-51 | 34.04% (426) | 4-aminobutyrate aminotransferase, GabT_2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5273|M.vanbaalenii_PYR-1 ----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWVT
Mflv_4833|M.gilvum_PYR-GCK MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWMT
MSMEG_3900|M.smegmatis_MC2_155 -----MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWVT
TH_3246|M.thermoresistible__bu -------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWIT
MAB_2266c|M.abscessus_ATCC_199 -------MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLT
MMAR_0166|M.marinum_M -------------MLAKNPPPMR---ESNAATYSRRLPIRLVEARGTRVR
MUL_4930|M.ulcerans_Agy99 -------------MLAKNPPPMR---ESNAATYSRRLPIRLVEARGTRVR
Mb1683|M.bovis_AF2122/97 -----------MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVT
Rv1655|M.tuberculosis_H37Rv -----------MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVT
MAV_3115|M.avium_104 --------------MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVT
MLBr_01409|M.leprae_Br4923 -----------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVT
: :: * : . .: :
Mvan_5273|M.vanbaalenii_PYR-1 DVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEAK
Mflv_4833|M.gilvum_PYR-GCK DTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAAK
MSMEG_3900|M.smegmatis_MC2_155 DVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTAK
TH_3246|M.thermoresistible__bu DVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAAK
MAB_2266c|M.abscessus_ATCC_199 DTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDGVVHGLDMATVAK
MMAR_0166|M.marinum_M DSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPAR
MUL_4930|M.ulcerans_Agy99 DSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPAR
Mb1683|M.bovis_AF2122/97 DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLG-HTSNLYATEPG
Rv1655|M.tuberculosis_H37Rv DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLG-HTSNLYATEPG
MAV_3115|M.avium_104 DVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLG-HTSNLYATEPS
MLBr_01409|M.leprae_Br4923 DVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLG-HTSNLYATEPS
* ... *:* :.. .. * .:* : .: : . * .
Mvan_5273|M.vanbaalenii_PYR-1 TRFLETFERLILRPRG------------LDYKVQFPGPTGANTVEAALKL
Mflv_4833|M.gilvum_PYR-GCK TEFLETFERLILRPRS------------LDYKVQFPGPTGANAVESALKL
MSMEG_3900|M.smegmatis_MC2_155 QRFLETFQRAILQPRN------------LDYKVQFPGPTGANAVESALKL
TH_3246|M.thermoresistible__bu QEFLETFSELILKPRG------------LDYKVQFPGPTGANAVESALKL
MAB_2266c|M.abscessus_ATCC_199 QQFLEEFERTILLPRG------------MDYKVQFPGPTGTNAVESALKL
MMAR_0166|M.marinum_M EQFVEDLLSILPPGLA------------ADGRVHLCSPSGASAVEAALTL
MUL_4930|M.ulcerans_Agy99 EQFVEDLLSILPPGLA------------ADGRVHLCSPSGASAVEAALTL
Mb1683|M.bovis_AF2122/97 IALAEELVALLGADQR--------------TRVFFCN-SGAEANEAAFKL
Rv1655|M.tuberculosis_H37Rv IALAEELVALLGADQR--------------TRVFFCN-SGAEANEAAFKL
MAV_3115|M.avium_104 LALAEELVALLGAGHEPAGHESGGTESAGTARVFFCN-SGTEANEVAFKL
MLBr_01409|M.leprae_Br4923 ITLAEELVALLGADTQ--------------TRVFFCN-SGTEANELAFKL
: * : : :* : . :*:.: * *:.*
Mvan_5273|M.vanbaalenii_PYR-1 ARKVTGRESIISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
Mflv_4833|M.gilvum_PYR-GCK ARKVTGRESIINFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
MSMEG_3900|M.smegmatis_MC2_155 ARKVTGRESVISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
TH_3246|M.thermoresistible__bu ARKVTGRESIVSFTNAFHGMTLGALSVTGNSMKRAGAGVPLVHSTPMPYD
MAB_2266c|M.abscessus_ATCC_199 ARNITGRESIISFTNAFHGMTLGSLAVTGNSMKRAGAGVPLVHSTPMPYD
MMAR_0166|M.marinum_M AEIATGGREHVGVQGGFHGCTRAARAASSGGGLRQQPVVMAPRTTFLPFP
MUL_4930|M.ulcerans_Agy99 AEIATGGREHVGVQGGFHGCTRAARAASSGGGLRQQPVVMAPRTTFLPFP
Mb1683|M.bovis_AF2122/97 SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
Rv1655|M.tuberculosis_H37Rv SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
MAV_3115|M.avium_104 SR-LTGRTKLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHVPYG
MLBr_01409|M.leprae_Br4923 SR-LTGRTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG
:. ** . : .*** * .: : :. : * : :
Mvan_5273|M.vanbaalenii_PYR-1 NYFGG--------VTEDFHWFERVLDDSGSGLNRPAAVIVETVQGEGGLN
Mflv_4833|M.gilvum_PYR-GCK NYFGG--------ITEDFHWFERVLDDSGGGLNHPAAVIVETVQGEGGLN
MSMEG_3900|M.smegmatis_MC2_155 NYFDG--------VTEDFQWFGRVLDDSGSGLNRPAAVIVETVQGEGGLN
TH_3246|M.thermoresistible__bu NYFGG--------VTEDFQWFEKVLDDEGSGLNRPAAVIVETVQGEGGLN
MAB_2266c|M.abscessus_ATCC_199 NYFGG--------VTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVN
MMAR_0166|M.marinum_M QNYRCPFGVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVL
MUL_4930|M.ulcerans_Agy99 QNYRCPFGVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVL
Mb1683|M.bovis_AF2122/97 ----------------------DVDALAAAVDDHTAAVFLEPIMGESGVV
Rv1655|M.tuberculosis_H37Rv ----------------------DVDALAAAVDDHTAAVFLEPIMGESGVV
MAV_3115|M.avium_104 ----------------------DTEALAAAVDDGTAAVFLEPIMGESGVV
MLBr_01409|M.leprae_Br4923 ----------------------QVDALAAAVDNDTAAVFLEPIMGESGVI
. . .*::: * : **.*:
Mvan_5273|M.vanbaalenii_PYR-1 VARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIVT
Mflv_4833|M.gilvum_PYR-GCK VARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVT
MSMEG_3900|M.smegmatis_MC2_155 VARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIVT
TH_3246|M.thermoresistible__bu VARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIVT
MAB_2266c|M.abscessus_ATCC_199 VARAEWLQALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVT
MMAR_0166|M.marinum_M PAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVV
MUL_4930|M.ulcerans_Agy99 PAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVV
Mb1683|M.bovis_AF2122/97 VPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVT
Rv1655|M.tuberculosis_H37Rv VPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVT
MAV_3115|M.avium_104 VPPEGYLAAARDITARHGALLVLDEVQTGMGRTGTFFAHQHDGITPDVVT
MLBr_01409|M.leprae_Br4923 VPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVT
. : . :: *: *:** * *** :..: .* **:*.
Mvan_5273|M.vanbaalenii_PYR-1 LSKSISGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALETY
Mflv_4833|M.gilvum_PYR-GCK LSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALETY
MSMEG_3900|M.smegmatis_MC2_155 LSKSVSGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATQALQTY
TH_3246|M.thermoresistible__bu LSKSISGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPAFVTATAALKTY
MAB_2266c|M.abscessus_ATCC_199 LSKSISGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATLQKY
MMAR_0166|M.marinum_M MSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
MUL_4930|M.ulcerans_Agy99 MSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
Mb1683|M.bovis_AF2122/97 LAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
Rv1655|M.tuberculosis_H37Rv LAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
MAV_3115|M.avium_104 LAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLRVL
MLBr_01409|M.leprae_Br4923 LAKGLGGGLPIGAFLATGPAAELLTLGLHGSTFGGNPVCTAAALAVLRVL
::*.:. * : * . .** *: . .:* .:.
Mvan_5273|M.vanbaalenii_PYR-1 WETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED---
Mflv_4833|M.gilvum_PYR-GCK WKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE---
MSMEG_3900|M.smegmatis_MC2_155 WQDDKFSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD---
TH_3246|M.thermoresistible__bu WQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ---
MAB_2266c|M.abscessus_ATCC_199 WQDNTFSDDVRRKGDRLHDELTALVADDDSVS-IRGRGMVQGIAFAD---
MMAR_0166|M.marinum_M AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
MUL_4930|M.ulcerans_Agy99 AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
Mb1683|M.bovis_AF2122/97 ASDG-LVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP--
Rv1655|M.tuberculosis_H37Rv ASDG-LVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP--
MAV_3115|M.avium_104 ASEN-LVRHAEVLGKSLHQGIEGLG--HPLVDHVRGRGLLCGVVLTAP--
MLBr_01409|M.leprae_Br4923 ATQG-LVRRAEVLGDSMRIGIESLS--HPLIDQVRGRGLLLGIVLTAP--
: . * .: : : : ****: .
Mvan_5273|M.vanbaalenii_PYR-1 ---------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDL
Mflv_4833|M.gilvum_PYR-GCK ---------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDL
MSMEG_3900|M.smegmatis_MC2_155 ---------TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDL
TH_3246|M.thermoresistible__bu ---------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQEEL
MAB_2266c|M.abscessus_ATCC_199 ---------AERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQL
MMAR_0166|M.marinum_M PWPSGVAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
MUL_4930|M.ulcerans_Agy99 PWPSGVAPAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
Mb1683|M.bovis_AF2122/97 -----------HAKDAEATARDAGYLVNAAAP--DVIRLAPPLIIAEAQL
Rv1655|M.tuberculosis_H37Rv -----------HAKDAEATARDAGYLVNAAAP--DVIRLAPPLIIAEAQL
MAV_3115|M.avium_104 -----------RAKDAEAAAREAGFLVNAAAP--GVIRLAPPLIVTEAQI
MLBr_01409|M.leprae_Br4923 -----------RAKDIEKAARDAGFLVNATAP--EVIRLAPPLIITESQI
. :: . * :::: . *::: *.* ::
Mvan_5273|M.vanbaalenii_PYR-1 DSGIDILAEAIAVTVA-------------
Mflv_4833|M.gilvum_PYR-GCK DAGLDILAEAVATTVS-------------
MSMEG_3900|M.smegmatis_MC2_155 EAGLDILAESIAVTLS-------------
TH_3246|M.thermoresistible__bu EAGLGILADAVAATVD-------------
MAB_2266c|M.abscessus_ATCC_199 DIGIATLREAITESAQ-------------
MMAR_0166|M.marinum_M SAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99 SAALTAFEAAVKQVERHRTKAVDLRADQR
Mb1683|M.bovis_AF2122/97 DGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv DGFVAALPAILDRAVGAP-----------
MAV_3115|M.avium_104 DGFIAALPGILDRAAA-------------
MLBr_01409|M.leprae_Br4923 DSFITALPGILDASIAELGKKA-------
. : : :