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MLAKNPPPMRESNAATYSRRLPIRLVEARGTRVRDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDS GEPWLSLDFHTPAREQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAEIATGGREHVGVQGGFH GCTRAARAASSGGGLRQQPVVMAPRTTFLPFPQNYRCPFGVGGERGVDLAVTAVEQLAAPHAGISAPASI ISEFVLGEGGVLPAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVVMSKGLGSG VPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIRYAREAALAEHVTRMGEYFRTGLQRILEECEI VGDVRGRGLMLAAEIVDPQLPWPSGVAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADI SAALTAFEAAVKQVERHRTKAVDLRADQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0166 | gabT_2 | - | 100% (449) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. marinum M | MMAR_2118 | gabT | 6e-39 | 30.81% (422) | 4-aminobutyrate aminotransferase GabT |
| M. marinum M | MMAR_2465 | argD | 2e-38 | 30.71% (407) | acetylornithine aminotransferase ArgD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 4e-37 | 31.78% (409) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_4833 | - | 6e-54 | 33.49% (424) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 4e-37 | 31.78% (409) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 8e-37 | 31.26% (419) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_1684 | - | 0.0 | 72.33% (430) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. avium 104 | MAV_3115 | argD | 3e-36 | 30.31% (419) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3900 | ectB | 9e-48 | 31.12% (421) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 1e-55 | 33.73% (424) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_4930 | gabT_2 | 0.0 | 99.55% (449) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. vanbaalenii PYR-1 | Mvan_5273 | - | 1e-50 | 34.04% (426) | diaminobutyrate--2-oxoglutarate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0166|M.marinum_M -----------------MLAKNPPPMRESNAATYSRRLPIRLVEARGTRV
MUL_4930|M.ulcerans_Agy99 -----------------MLAKNPPPMRESNAATYSRRLPIRLVEARGTRV
MAB_1684|M.abscessus_ATCC_1997 ----------------MTVSQFTSTARESAAATYSRRLPIRPVEARGARV
MSMEG_3900|M.smegmatis_MC2_155 ------MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWV
TH_3246|M.thermoresistible__bu --------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWI
Mflv_4833|M.gilvum_PYR-GCK -MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWM
Mvan_5273|M.vanbaalenii_PYR-1 -----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWV
Mb1683|M.bovis_AF2122/97 -----------MTGASTTTATMRQRWQAVMMNNYG-TPPIALASGDGAVV
Rv1655|M.tuberculosis_H37Rv -----------MTGASTTTATMRQRWQAVMMNNYG-TPPIALASGDGAVV
MAV_3115|M.avium_104 --------------MVTNTDALRRRWEAVMMHNYG-TPPVALASGEGAVV
MLBr_00485|M.leprae_Br4923 MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAAGGVI
* . . :
MMAR_0166|M.marinum_M RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPA
MUL_4930|M.ulcerans_Agy99 RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPA
MAB_1684|M.abscessus_ATCC_1997 RAEDGRWYVDCLAAAGAMSLGWNHPAVNEAVMKTVSSGEPLLSLDFHTPS
MSMEG_3900|M.smegmatis_MC2_155 TDVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTA
TH_3246|M.thermoresistible__bu TDVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAA
Mflv_4833|M.gilvum_PYR-GCK TDTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAA
Mvan_5273|M.vanbaalenii_PYR-1 TDVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEA
Mb1683|M.bovis_AF2122/97 TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPG
Rv1655|M.tuberculosis_H37Rv TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPG
MAV_3115|M.avium_104 TDVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLYATEPS
MLBr_00485|M.leprae_Br4923 EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEE
.*. :* .. .. * * : .: : :
MMAR_0166|M.marinum_M REQFVEDLLSILPPGL----------AADGRVHLCSPSGASAVEAALTLA
MUL_4930|M.ulcerans_Agy99 REQFVEDLLSILPPGL----------AADGRVHLCSPSGASAVEAALTLA
MAB_1684|M.abscessus_ATCC_1997 RDRFVEELLSILPVRL----------ATDASIHLCSPSGASAVEAALMLA
MSMEG_3900|M.smegmatis_MC2_155 KQRFLETFQRAILQPR----------NLDYKVQFPGPTGANAVESALKLA
TH_3246|M.thermoresistible__bu KQEFLETFSELILKPR----------GLDYKVQFPGPTGANAVESALKLA
Mflv_4833|M.gilvum_PYR-GCK KTEFLETFERLILRPR----------SLDYKVQFPGPTGANAVESALKLA
Mvan_5273|M.vanbaalenii_PYR-1 KTRFLETFERLILRPR----------GLDYKVQFPGPTGANTVEAALKLA
Mb1683|M.bovis_AF2122/97 IALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKLS
Rv1655|M.tuberculosis_H37Rv IALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKLS
MAV_3115|M.avium_104 LALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLS
MLBr_00485|M.leprae_Br4923 YVAVTEQLNRITPGSG-------------EKRSVLFNSGAEAVENSIKVA
* . . :*:.: * :: ::
MMAR_0166|M.marinum_M EIATGGREHVGVQGGFHGCTRAARAASSGGG-LRQQPVVMAPRTTFLPFP
MUL_4930|M.ulcerans_Agy99 EIATGGREHVGVQGGFHGCTRAARAASSGGG-LRQQPVVMAPRTTFLPFP
MAB_1684|M.abscessus_ATCC_1997 EIATGGREHIGVQGGFHGCTRAARAASSGGG-LRRQPVVLSPQASFLPYP
MSMEG_3900|M.smegmatis_MC2_155 RKVTGRESVISFTNAFHGMTLGALSVTGNSM-KRAGAGIPLVHATPMPYD
TH_3246|M.thermoresistible__bu RKVTGRESIVSFTNAFHGMTLGALSVTGNSM-KRAGAGVPLVHSTPMPYD
Mflv_4833|M.gilvum_PYR-GCK RKVTGRESIINFTNAFHGMTLGALSVTGNSM-KRAGAGIPLVHATPMPYD
Mvan_5273|M.vanbaalenii_PYR-1 RKVTGRESIISFTNAFHGMTLGALSVTGNSM-KRAGAGIPLVHATPMPYD
Mb1683|M.bovis_AF2122/97 R-LTGRTKLVAAHDAFHGRTMGSLALTGQPA-KQTPFAPLPGDVTHVGYG
Rv1655|M.tuberculosis_H37Rv R-LTGRTKLVAAHDAFHGRTMGSLALTGQPA-KQTPFAPLPGDVTHVGYG
MAV_3115|M.avium_104 R-LTGRTKLVAAQEAFHGRTMGSLALTGQPS-KQAPFAPLPGDVTHVPYG
MLBr_00485|M.leprae_Br4923 RSYTRKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLS
. * : .:** * : : :. :
MMAR_0166|M.marinum_M QNYRCPF-GVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGV
MUL_4930|M.ulcerans_Agy99 QNYRCPF-GVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGV
MAB_1684|M.abscessus_ATCC_1997 QEYRSPF-GVSGERGVELAIAAAEAVARPHSGVTAPASLIAEFVLGEGGV
MSMEG_3900|M.smegmatis_MC2_155 NYFDG---------VTEDFQWFGRVLDDSGSGLNRPAAVIVETVQGEGGL
TH_3246|M.thermoresistible__bu NYFGG---------VTEDFQWFEKVLDDEGSGLNRPAAVIVETVQGEGGL
Mflv_4833|M.gilvum_PYR-GCK NYFGG---------ITEDFHWFERVLDDSGGGLNHPAAVIVETVQGEGGL
Mvan_5273|M.vanbaalenii_PYR-1 NYFGG---------VTEDFHWFERVLDDSGSGLNRPAAVIVETVQGEGGL
Mb1683|M.bovis_AF2122/97 ----------------------DVDALAAAV-DDHTAAVFLEPIMGESGV
Rv1655|M.tuberculosis_H37Rv ----------------------DVDALAAAV-DDHTAAVFLEPIMGESGV
MAV_3115|M.avium_104 ----------------------DTEALAAAV-DDGTAAVFLEPIMGESGV
MLBr_00485|M.leprae_Br4923 YPYRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGF
*::: * : **.*.
MMAR_0166|M.marinum_M LPAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMV
MUL_4930|M.ulcerans_Agy99 LPAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMV
MAB_1684|M.abscessus_ATCC_1997 IPAPARWGQALRRTASTLGVPLIADEVQAGMYRTGPAWAFQHSGIEPDMM
MSMEG_3900|M.smegmatis_MC2_155 NVARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIV
TH_3246|M.thermoresistible__bu NVARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIV
Mflv_4833|M.gilvum_PYR-GCK NVARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIV
Mvan_5273|M.vanbaalenii_PYR-1 NVARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIV
Mb1683|M.bovis_AF2122/97 VVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVV
Rv1655|M.tuberculosis_H37Rv VVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVV
MAV_3115|M.avium_104 VVPPEGYLAAARDITARHGALLVLDEVQTGMGRTGTFFAHQHDGITPDVV
MLBr_00485|M.leprae_Br4923 IVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDGIVPDLI
. : :: *:** * *** :. : .* **::
MMAR_0166|M.marinum_M VMSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-
MUL_4930|M.ulcerans_Agy99 VMSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-
MAB_1684|M.abscessus_ATCC_1997 VISKGLG-SGIPIAVLVVRKEFDVWEPGAFTGTFRGNAMAFAAASAVIR-
MSMEG_3900|M.smegmatis_MC2_155 TLSKSVSGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATQALQT
TH_3246|M.thermoresistible__bu TLSKSISGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPAFVTATAALKT
Mflv_4833|M.gilvum_PYR-GCK TLSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALET
Mvan_5273|M.vanbaalenii_PYR-1 TLSKSISGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALET
Mb1683|M.bovis_AF2122/97 TLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLR-
Rv1655|M.tuberculosis_H37Rv TLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLR-
MAV_3115|M.avium_104 TLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLR-
MLBr_00485|M.leprae_Br4923 CTAKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATIT-
:*.:. * : . .** *: . .:* .:
MMAR_0166|M.marinum_M YAREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQ
MUL_4930|M.ulcerans_Agy99 YAREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQ
MAB_1684|M.abscessus_ATCC_1997 FARENGLRGQVTARGKIFLDGLNAVASDSALVGDVRGVGLMLGVEIVDPD
MSMEG_3900|M.smegmatis_MC2_155 YWQDDKFSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD--
TH_3246|M.thermoresistible__bu YWQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ--
Mflv_4833|M.gilvum_PYR-GCK YWKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE--
Mvan_5273|M.vanbaalenii_PYR-1 YWETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED--
Mb1683|M.bovis_AF2122/97 VLASDGLVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP-
Rv1655|M.tuberculosis_H37Rv VLASDGLVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP-
MAV_3115|M.avium_104 VLASENLVRHAEVLGKSLHQGIEGLG--HPLVDHVRGRGLLCGVVLTAP-
MLBr_00485|M.leprae_Br4923 TIENDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSG
: . . . : : : .** * .
MMAR_0166|M.marinum_M LPWPSGV-APAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEA
MUL_4930|M.ulcerans_Agy99 LPWPSGV-APAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEA
MAB_1684|M.abscessus_ATCC_1997 MPWPDDAGAPAPELAARIQQACLQHGLIVETGGQYGNVVRFLPPLTIDEP
MSMEG_3900|M.smegmatis_MC2_155 -----------TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSRE
TH_3246|M.thermoresistible__bu -----------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQE
Mflv_4833|M.gilvum_PYR-GCK -----------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTE
Mvan_5273|M.vanbaalenii_PYR-1 -----------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEE
Mb1683|M.bovis_AF2122/97 ------------HAKDAEATARDAG---YLVNAAAPDVIRLAPPLIIAEA
Rv1655|M.tuberculosis_H37Rv ------------HAKDAEATARDAG---YLVNAAAPDVIRLAPPLIIAEA
MAV_3115|M.avium_104 ------------RAKDAEAAAREAG---FLVNAAAPGVIRLAPPLIVTEA
MLBr_00485|M.leprae_Br4923 TA------EPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDE
: . :::: ***
MMAR_0166|M.marinum_M DISAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99 DISAALTAFEAAVKQVERHRTKAVDLRADQR
MAB_1684|M.abscessus_ATCC_1997 DIAAALNAFDAALSAVERTR-----------
MSMEG_3900|M.smegmatis_MC2_155 DLEAGLDILAESIAVTLS-------------
TH_3246|M.thermoresistible__bu ELEAGLGILADAVAATVD-------------
Mflv_4833|M.gilvum_PYR-GCK DLDAGLDILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1 DLDSGIDILAEAIAVTVA-------------
Mb1683|M.bovis_AF2122/97 QLDGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv QLDGFVAALPAILDRAVGAP-----------
MAV_3115|M.avium_104 QIDGFIAALPGILDRAAA-------------
MLBr_00485|M.leprae_Br4923 LLAEGLDILSRILGDF---------------
: : : :