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LLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWVTDVDGRRYIDFFAGAGALNYGHNNPKL KAPLLDYLASDGIVHSLDMATTAKQRFLETFQRAILQPRNLDYKVQFPGPTGANAVESALKLARKVTGRE SVISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYDNYFDGVTEDFQWFGRVLDDSGSGLNRPA AVIVETVQGEGGLNVARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIVTLSKSVS GYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATQALQTYWQDDKFSAATFQKGELIRSRLDEIAD RYDGVTARGRGMAQGLKFADTERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDLEAGLDILAE SIAVTLS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3900 | ectB | - | 100% (428) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_1413 | rocD | 1e-41 | 30.64% (408) | ornithine--oxo-acid transaminase |
| M. smegmatis MC2 155 | MSMEG_2487 | - | 3e-39 | 31.50% (400) | 4-aminobutyrate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 2e-36 | 30.02% (423) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_4833 | - | 0.0 | 78.95% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 2e-36 | 30.02% (423) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 8e-41 | 32.20% (410) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_2266c | - | 1e-179 | 71.26% (421) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. marinum M | MMAR_0166 | gabT_2 | 9e-48 | 31.12% (421) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. avium 104 | MAV_3470 | gabT | 1e-36 | 31.89% (417) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 0.0 | 82.19% (421) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_4930 | gabT_2 | 3e-48 | 31.12% (421) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. vanbaalenii PYR-1 | Mvan_5273 | - | 0.0 | 80.86% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3900|M.smegmatis_MC2_155 ------MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWV
TH_3246|M.thermoresistible__bu --------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWI
Mflv_4833|M.gilvum_PYR-GCK -MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWM
Mvan_5273|M.vanbaalenii_PYR-1 -----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWV
MAB_2266c|M.abscessus_ATCC_199 --------MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWL
MMAR_0166|M.marinum_M --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
MUL_4930|M.ulcerans_Agy99 --------MLAKNPP---------PMRESNAATYSRRLPIRLVEARGTRV
Mb2620|M.bovis_AF2122/97 MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAGGGIV
Rv2589|M.tuberculosis_H37Rv MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAGGGIV
MAV_3470|M.avium_104 MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAGGGIV
MLBr_00485|M.leprae_Br4923 MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAAGGVI
: * . * . :
MSMEG_3900|M.smegmatis_MC2_155 TDVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTA
TH_3246|M.thermoresistible__bu TDVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAA
Mflv_4833|M.gilvum_PYR-GCK TDTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAA
Mvan_5273|M.vanbaalenii_PYR-1 TDVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEA
MAB_2266c|M.abscessus_ATCC_199 TDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDGVVHGLDMATVA
MMAR_0166|M.marinum_M RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPA
MUL_4930|M.ulcerans_Agy99 RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPA
Mb2620|M.bovis_AF2122/97 EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEG
Rv2589|M.tuberculosis_H37Rv EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEG
MAV_3470|M.avium_104 EDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVTPYES
MLBr_00485|M.leprae_Br4923 EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEE
* .*. :* :. .. . * . * : .: : :
MSMEG_3900|M.smegmatis_MC2_155 KQRFLETFQRAILQPRNLDYKVQFPGPTGANAVESALKLARKVTGRESVI
TH_3246|M.thermoresistible__bu KQEFLETFSELILKPRGLDYKVQFPGPTGANAVESALKLARKVTGRESIV
Mflv_4833|M.gilvum_PYR-GCK KTEFLETFERLILRPRSLDYKVQFPGPTGANAVESALKLARKVTGRESII
Mvan_5273|M.vanbaalenii_PYR-1 KTRFLETFERLILRPRGLDYKVQFPGPTGANTVEAALKLARKVTGRESII
MAB_2266c|M.abscessus_ATCC_199 KQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLARNITGRESII
MMAR_0166|M.marinum_M REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAEIATGGREHV
MUL_4930|M.ulcerans_Agy99 REQFVEDLLSILPPGLAADGRVHLCSPSGASAVEAALTLAEIATGGREHV
Mb2620|M.bovis_AF2122/97 YVAVAEQLNRITP---GSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVV
Rv2589|M.tuberculosis_H37Rv YVAVAEQLNRITP---GSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVV
MAV_3470|M.avium_104 YVAVAETLNRITP---GAGEKRSVLFNSGAEAVENAVKVARAYTRKPAVV
MLBr_00485|M.leprae_Br4923 YVAVTEQLNRITP---GSGEKRSVLFNSGAEAVENSIKVARSYTRKPAVV
. * : . : . :*:.:** ::.:*. * :
MSMEG_3900|M.smegmatis_MC2_155 SFTNAFHGMTLGALSVTGNSMKRA---GAGIPLVHATPMPYDNYFDG---
TH_3246|M.thermoresistible__bu SFTNAFHGMTLGALSVTGNSMKRA---GAGVPLVHSTPMPYDNYFGG---
Mflv_4833|M.gilvum_PYR-GCK NFTNAFHGMTLGALSVTGNSMKRA---GAGIPLVHATPMPYDNYFGG---
Mvan_5273|M.vanbaalenii_PYR-1 SFTNAFHGMTLGALSVTGNSMKRA---GAGIPLVHATPMPYDNYFGG---
MAB_2266c|M.abscessus_ATCC_199 SFTNAFHGMTLGSLAVTGNSMKRA---GAGVPLVHSTPMPYDNYFGG---
MMAR_0166|M.marinum_M GVQGGFHGCTRAARAASSGGGLRQ---QPVVMAPRTTFLPFPQNYRCPFG
MUL_4930|M.ulcerans_Agy99 GVQGGFHGCTRAARAASSGGGLRQ---QPVVMAPRTTFLPFPQNYRCPFG
Mb2620|M.bovis_AF2122/97 AFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYP-YRDGLLD
Rv2589|M.tuberculosis_H37Rv AFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYP-YRDGLLD
MAV_3470|M.avium_104 AFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYP-YRDGLLD
MLBr_00485|M.leprae_Br4923 AFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYP-YRDGLLN
. .:** * : : :. . . : :.:
MSMEG_3900|M.smegmatis_MC2_155 -----VTEDFQWFGRVLDDSGSGLNRPAAVIVETVQGEGGLNVARVEWLQ
TH_3246|M.thermoresistible__bu -----VTEDFQWFEKVLDDEGSGLNRPAAVIVETVQGEGGLNVARAEWLR
Mflv_4833|M.gilvum_PYR-GCK -----ITEDFHWFERVLDDSGGGLNHPAAVIVETVQGEGGLNVARMEWLR
Mvan_5273|M.vanbaalenii_PYR-1 -----VTEDFHWFERVLDDSGSGLNRPAAVIVETVQGEGGLNVARVEWLR
MAB_2266c|M.abscessus_ATCC_199 -----VTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQ
MMAR_0166|M.marinum_M VGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVLPAHPRWAK
MUL_4930|M.ulcerans_Agy99 VGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVLPAHPRWAK
Mb2620|M.bovis_AF2122/97 KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFLP
Rv2589|M.tuberculosis_H37Rv KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFLP
MAV_3470|M.avium_104 KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAEGFLP
MLBr_00485|M.leprae_Br4923 KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAEGFLA
. : * . *::: * : ****. . :
MSMEG_3900|M.smegmatis_MC2_155 ALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAG---IVPDIVTLSKSV
TH_3246|M.thermoresistible__bu ALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAG---ITPDIVTLSKSI
Mflv_4833|M.gilvum_PYR-GCK ALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAG---IVPDIVTLSKSI
Mvan_5273|M.vanbaalenii_PYR-1 GLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAG---IVPDIVTLSKSI
MAB_2266c|M.abscessus_ATCC_199 ALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAG---IKPDIVTLSKSI
MMAR_0166|M.marinum_M ALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCD---IEPDMVVMSKGL
MUL_4930|M.ulcerans_Agy99 ALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCD---IEPDMVVMSKGL
Mb2620|M.bovis_AF2122/97 ALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKGI
Rv2589|M.tuberculosis_H37Rv ALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKGI
MAV_3470|M.avium_104 TLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICTAKAI
MLBr_00485|M.leprae_Br4923 TLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICTAKGI
* : .. .: :*.*:** * *:* :. * . : **:: :*.:
MSMEG_3900|M.smegmatis_MC2_155 SGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATQALQTYWQDDK
TH_3246|M.thermoresistible__bu SGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPAFVTATAALKTYWQDDS
Mflv_4833|M.gilvum_PYR-GCK SGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALETYWKSAT
Mvan_5273|M.vanbaalenii_PYR-1 SGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALETYWETET
MAB_2266c|M.abscessus_ATCC_199 SGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATLQKYWQDNT
MMAR_0166|M.marinum_M G-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-YAREAA
MUL_4930|M.ulcerans_Agy99 G-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-YAREAA
Mb2620|M.bovis_AF2122/97 ADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG-
Rv2589|M.tuberculosis_H37Rv ADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG-
MAV_3470|M.avium_104 ADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIESDG-
MLBr_00485|M.leprae_Br4923 ADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIENDG-
. *: : . *** *: * .:* .:
MSMEG_3900|M.smegmatis_MC2_155 FSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD--------
TH_3246|M.thermoresistible__bu FTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ--------
Mflv_4833|M.gilvum_PYR-GCK FAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE--------
Mvan_5273|M.vanbaalenii_PYR-1 FVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED--------
MAB_2266c|M.abscessus_ATCC_199 FSDDVRRKGDRLHDELTALVADDDSVS-IRGRGMVQGIAFAD--------
MMAR_0166|M.marinum_M LAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQLPWPSG
MUL_4930|M.ulcerans_Agy99 LAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQLPWPSG
Mb2620|M.bovis_AF2122/97 LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSG-----T
Rv2589|M.tuberculosis_H37Rv LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSG-----T
MAV_3470|M.avium_104 LIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSG-----T
MLBr_00485|M.leprae_Br4923 LIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSG-----T
: . . * : : **** . .
MSMEG_3900|M.smegmatis_MC2_155 ----TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDLEAGLD
TH_3246|M.thermoresistible__bu ----EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQEELEAGLG
Mflv_4833|M.gilvum_PYR-GCK ----KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDLDAGLD
Mvan_5273|M.vanbaalenii_PYR-1 ----AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDLDSGID
MAB_2266c|M.abscessus_ATCC_199 ----AERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQLDIGIA
MMAR_0166|M.marinum_M VAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADISAALT
MUL_4930|M.ulcerans_Agy99 VAPAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEADISAALT
Mb2620|M.bovis_AF2122/97 TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLD
Rv2589|M.tuberculosis_H37Rv TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLD
MAV_3470|M.avium_104 AEPDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGID
MLBr_00485|M.leprae_Br4923 AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLD
:: * :: : * .:::::**.** : .:
MSMEG_3900|M.smegmatis_MC2_155 ILAESIAVTLS-------------
TH_3246|M.thermoresistible__bu ILADAVAATVD-------------
Mflv_4833|M.gilvum_PYR-GCK ILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1 ILAEAIAVTVA-------------
MAB_2266c|M.abscessus_ATCC_199 TLREAITESAQ-------------
MMAR_0166|M.marinum_M AFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99 AFEAAVKQVERHRTKAVDLRADQR
Mb2620|M.bovis_AF2122/97 IVCAILADL---------------
Rv2589|M.tuberculosis_H37Rv IVCAILADL---------------
MAV_3470|M.avium_104 ILGGLLADL---------------
MLBr_00485|M.leprae_Br4923 ILSRILGDF---------------
. :