For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_2266c (-)

annotation: diaminobutyrate--2-oxoglutarate aminotransferase
coordinates: 2312626 - 2313906
length: 426

TATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGALNYGHNNPVLKT
ALIDYLTTDGVVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLARNITGRESI
ISFTNAFHGMTLGSLAVTGNSMKRAGAGVPLVHSTPMPYDNYFGGVTEDFQWFEKVLDDEGGGLNKPAAV
IVETVQGEGGVNVARAEWLQALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGY
GLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATLQKYWQDNTFSDDVRRKGDRLHDELTALVADD
DSVSIRGRGMVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQLDIGIATLREAI
TESAQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2266c--100% (426)diaminobutyrate--2-oxoglutarate aminotransferase
M. abscessus ATCC 19977MAB_1684-5e-5131.79% (431) diaminobutyrate--2-oxoglutarate aminotransferase
M. abscessus ATCC 19977MAB_2339argD2e-4332.51% (406) acetylornithine aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1683argD2e-4134.01% (394) acetylornithine aminotransferase
M. gilvum PYR-GCKMflv_4833-0.071.77% (418) diaminobutyrate--2-oxoglutarate aminotransferase
M. tuberculosis H37RvRv1655argD2e-4134.01% (394) acetylornithine aminotransferase
M. leprae Br4923MLBr_01409argD2e-4133.33% (396) acetylornithine aminotransferase
M. marinum MMMAR_0166gabT_22e-5432.63% (429) 4-aminobutyrate aminotransferase, GabT_2
M. avium 104MAV_3115argD1e-4233.57% (414) acetylornithine aminotransferase
M. smegmatis MC2 155MSMEG_3900ectB1e-17971.26% (421) diaminobutyrate--2-oxoglutarate aminotransferase
M. thermoresistible (build 8)TH_3246-0.072.68% (421) PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase
M. ulcerans Agy99MUL_4930gabT_24e-5532.63% (429) 4-aminobutyrate aminotransferase, GabT_2
M. vanbaalenii PYR-1Mvan_5273-1e-18073.12% (413) diaminobutyrate--2-oxoglutarate aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3900|M.smegmatis_MC2_155      -----MLLAANAQLTESDLPEVFSTVESEVRSYCRGWPAVMETAKDSWVT
TH_3246|M.thermoresistible__bu      -------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVMESARGSWIT
Mflv_4833|M.gilvum_PYR-GCK          MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWMT
Mvan_5273|M.vanbaalenii_PYR-1       ----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWVT
MAB_2266c|M.abscessus_ATCC_199      -------MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLT
MMAR_0166|M.marinum_M               -------------MLAKNPPPMR---ESNAATYSRRLPIRLVEARGTRVR
MUL_4930|M.ulcerans_Agy99           -------------MLAKNPPPMR---ESNAATYSRRLPIRLVEARGTRVR
Mb1683|M.bovis_AF2122/97            -----------MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVT
Rv1655|M.tuberculosis_H37Rv         -----------MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVT
MAV_3115|M.avium_104                --------------MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVT
MLBr_01409|M.leprae_Br4923          -----------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVT
                                                         :    ::         *  :  . .: : 

MSMEG_3900|M.smegmatis_MC2_155      DVDGRRYIDFFAGAGALNYGHNNPKLKAPLLDYLASDGIVHSLDMATTAK
TH_3246|M.thermoresistible__bu      DVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAAK
Mflv_4833|M.gilvum_PYR-GCK          DTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAAK
Mvan_5273|M.vanbaalenii_PYR-1       DVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEAK
MAB_2266c|M.abscessus_ATCC_199      DTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDGVVHGLDMATVAK
MMAR_0166|M.marinum_M               DSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPAR
MUL_4930|M.ulcerans_Agy99           DSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPAR
Mb1683|M.bovis_AF2122/97            DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLG-HTSNLYATEPG
Rv1655|M.tuberculosis_H37Rv         DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLG-HTSNLYATEPG
MAV_3115|M.avium_104                DVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLG-HTSNLYATEPS
MLBr_01409|M.leprae_Br4923          DVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLG-HTSNLYATEPS
                                    * ... *:* :.. ..   * .:* :  .:   :       .    * . 

MSMEG_3900|M.smegmatis_MC2_155      QRFLETFQRAILQPRN------------LDYKVQFPGPTGANAVESALKL
TH_3246|M.thermoresistible__bu      QEFLETFSELILKPRG------------LDYKVQFPGPTGANAVESALKL
Mflv_4833|M.gilvum_PYR-GCK          TEFLETFERLILRPRS------------LDYKVQFPGPTGANAVESALKL
Mvan_5273|M.vanbaalenii_PYR-1       TRFLETFERLILRPRG------------LDYKVQFPGPTGANTVEAALKL
MAB_2266c|M.abscessus_ATCC_199      QQFLEEFERTILLPRG------------MDYKVQFPGPTGTNAVESALKL
MMAR_0166|M.marinum_M               EQFVEDLLSILPPGLA------------ADGRVHLCSPSGASAVEAALTL
MUL_4930|M.ulcerans_Agy99           EQFVEDLLSILPPGLA------------ADGRVHLCSPSGASAVEAALTL
Mb1683|M.bovis_AF2122/97            IALAEELVALLGADQR--------------TRVFFCN-SGAEANEAAFKL
Rv1655|M.tuberculosis_H37Rv         IALAEELVALLGADQR--------------TRVFFCN-SGAEANEAAFKL
MAV_3115|M.avium_104                LALAEELVALLGAGHEPAGHESGGTESAGTARVFFCN-SGTEANEVAFKL
MLBr_01409|M.leprae_Br4923          ITLAEELVALLGADTQ--------------TRVFFCN-SGTEANELAFKL
                                      : * :   :                    :* : . :*:.: * *:.*

MSMEG_3900|M.smegmatis_MC2_155      ARKVTGRESVISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
TH_3246|M.thermoresistible__bu      ARKVTGRESIVSFTNAFHGMTLGALSVTGNSMKRAGAGVPLVHSTPMPYD
Mflv_4833|M.gilvum_PYR-GCK          ARKVTGRESIINFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
Mvan_5273|M.vanbaalenii_PYR-1       ARKVTGRESIISFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHATPMPYD
MAB_2266c|M.abscessus_ATCC_199      ARNITGRESIISFTNAFHGMTLGSLAVTGNSMKRAGAGVPLVHSTPMPYD
MMAR_0166|M.marinum_M               AEIATGGREHVGVQGGFHGCTRAARAASSGGGLRQQPVVMAPRTTFLPFP
MUL_4930|M.ulcerans_Agy99           AEIATGGREHVGVQGGFHGCTRAARAASSGGGLRQQPVVMAPRTTFLPFP
Mb1683|M.bovis_AF2122/97            SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
Rv1655|M.tuberculosis_H37Rv         SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
MAV_3115|M.avium_104                SR-LTGRTKLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHVPYG
MLBr_01409|M.leprae_Br4923          SR-LTGRTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG
                                    :.  **  . :    .*** * .: : :.    :          * : : 

MSMEG_3900|M.smegmatis_MC2_155      NYFDG--------VTEDFQWFGRVLDDSGSGLNRPAAVIVETVQGEGGLN
TH_3246|M.thermoresistible__bu      NYFGG--------VTEDFQWFEKVLDDEGSGLNRPAAVIVETVQGEGGLN
Mflv_4833|M.gilvum_PYR-GCK          NYFGG--------ITEDFHWFERVLDDSGGGLNHPAAVIVETVQGEGGLN
Mvan_5273|M.vanbaalenii_PYR-1       NYFGG--------VTEDFHWFERVLDDSGSGLNRPAAVIVETVQGEGGLN
MAB_2266c|M.abscessus_ATCC_199      NYFGG--------VTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVN
MMAR_0166|M.marinum_M               QNYRCPFGVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVL
MUL_4930|M.ulcerans_Agy99           QNYRCPFGVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGVL
Mb1683|M.bovis_AF2122/97            ----------------------DVDALAAAVDDHTAAVFLEPIMGESGVV
Rv1655|M.tuberculosis_H37Rv         ----------------------DVDALAAAVDDHTAAVFLEPIMGESGVV
MAV_3115|M.avium_104                ----------------------DTEALAAAVDDGTAAVFLEPIMGESGVV
MLBr_01409|M.leprae_Br4923          ----------------------QVDALAAAVDNDTAAVFLEPIMGESGVI
                                                                 .  . .*::: * : **.*: 

MSMEG_3900|M.smegmatis_MC2_155      VARVEWLQALADLCRTRDILLIVDDVQMGCGRTGPFFSFEAAGIVPDIVT
TH_3246|M.thermoresistible__bu      VARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIVT
Mflv_4833|M.gilvum_PYR-GCK          VARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVT
Mvan_5273|M.vanbaalenii_PYR-1       VARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIVT
MAB_2266c|M.abscessus_ATCC_199      VARAEWLQALADLCRKREIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVT
MMAR_0166|M.marinum_M               PAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVV
MUL_4930|M.ulcerans_Agy99           PAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMVV
Mb1683|M.bovis_AF2122/97            VPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVT
Rv1655|M.tuberculosis_H37Rv         VPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVT
MAV_3115|M.avium_104                VPPEGYLAAARDITARHGALLVLDEVQTGMGRTGTFFAHQHDGITPDVVT
MLBr_01409|M.leprae_Br4923          VPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVT
                                     .   :  .  ::       *: *:** *  ***  :..:  .* **:*.

MSMEG_3900|M.smegmatis_MC2_155      LSKSVSGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATQALQTY
TH_3246|M.thermoresistible__bu      LSKSISGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPAFVTATAALKTY
Mflv_4833|M.gilvum_PYR-GCK          LSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALETY
Mvan_5273|M.vanbaalenii_PYR-1       LSKSISGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALETY
MAB_2266c|M.abscessus_ATCC_199      LSKSISGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATLQKY
MMAR_0166|M.marinum_M               MSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
MUL_4930|M.ulcerans_Agy99           MSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-Y
Mb1683|M.bovis_AF2122/97            LAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
Rv1655|M.tuberculosis_H37Rv         LAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL
MAV_3115|M.avium_104                LAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLRVL
MLBr_01409|M.leprae_Br4923          LAKGLGGGLPIGAFLATGPAAELLTLGLHGSTFGGNPVCTAAALAVLRVL
                                    ::*.:.      *        :    * . .** *:  . .:*  .:.  

MSMEG_3900|M.smegmatis_MC2_155      WQDDKFSAATFQKGELIRSRLDEIADRYDGVT-ARGRGMAQGLKFAD---
TH_3246|M.thermoresistible__bu      WQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ---
Mflv_4833|M.gilvum_PYR-GCK          WKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE---
Mvan_5273|M.vanbaalenii_PYR-1       WETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED---
MAB_2266c|M.abscessus_ATCC_199      WQDNTFSDDVRRKGDRLHDELTALVADDDSVS-IRGRGMVQGIAFAD---
MMAR_0166|M.marinum_M               AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
MUL_4930|M.ulcerans_Agy99           AREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQL
Mb1683|M.bovis_AF2122/97            ASDG-LVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP--
Rv1655|M.tuberculosis_H37Rv         ASDG-LVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP--
MAV_3115|M.avium_104                ASEN-LVRHAEVLGKSLHQGIEGLG--HPLVDHVRGRGLLCGVVLTAP--
MLBr_01409|M.leprae_Br4923          ATQG-LVRRAEVLGDSMRIGIESLS--HPLIDQVRGRGLLLGIVLTAP--
                                         :   .   *  .:  :  :      :   ****:  .        

MSMEG_3900|M.smegmatis_MC2_155      ---------TERAGEVCKAAFDRGALMETSGPSDEVVKLLPPLTTSREDL
TH_3246|M.thermoresistible__bu      ---------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQEEL
Mflv_4833|M.gilvum_PYR-GCK          ---------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTEDL
Mvan_5273|M.vanbaalenii_PYR-1       ---------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEEDL
MAB_2266c|M.abscessus_ATCC_199      ---------AERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQL
MMAR_0166|M.marinum_M               PWPSGVAPAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
MUL_4930|M.ulcerans_Agy99           PWPSGVAPAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEADI
Mb1683|M.bovis_AF2122/97            -----------HAKDAEATARDAGYLVNAAAP--DVIRLAPPLIIAEAQL
Rv1655|M.tuberculosis_H37Rv         -----------HAKDAEATARDAGYLVNAAAP--DVIRLAPPLIIAEAQL
MAV_3115|M.avium_104                -----------RAKDAEAAAREAGFLVNAAAP--GVIRLAPPLIVTEAQI
MLBr_01409|M.leprae_Br4923          -----------RAKDIEKAARDAGFLVNATAP--EVIRLAPPLIITESQI
                                                .     :: . * :::: .    *::: *.*     ::

MSMEG_3900|M.smegmatis_MC2_155      EAGLDILAESIAVTLS-------------
TH_3246|M.thermoresistible__bu      EAGLGILADAVAATVD-------------
Mflv_4833|M.gilvum_PYR-GCK          DAGLDILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1       DSGIDILAEAIAVTVA-------------
MAB_2266c|M.abscessus_ATCC_199      DIGIATLREAITESAQ-------------
MMAR_0166|M.marinum_M               SAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99           SAALTAFEAAVKQVERHRTKAVDLRADQR
Mb1683|M.bovis_AF2122/97            DGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv         DGFVAALPAILDRAVGAP-----------
MAV_3115|M.avium_104                DGFIAALPGILDRAAA-------------
MLBr_01409|M.leprae_Br4923          DSFITALPGILDASIAELGKKA-------
                                    .  :  :   :