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VSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAARAFGGIVEDVDGNRLIDLGSGIAVTTV GNASPRVVAAVAEQAAEFTHTCFMVTPYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTF TRKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDAEFGGKELATDGELAARR AITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAEGFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEH EGPDGLVPDLIVTAKGIAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIESDNLVAR AAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVELVKSGTLEPDPELTRKLLTAAHAAGVIVLSCGTFG NVLRFLPPLAISDDLLLEGLDILELILRDL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3818 | - | - | 100% (450) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_0358 | - | 4e-50 | 34.32% (440) | hypothetical protein Mflv_0358 |
| M. gilvum PYR-GCK | Mflv_1055 | - | 5e-47 | 33.80% (432) | hypothetical protein Mflv_1055 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 0.0 | 78.89% (450) | 4-aminobutyrate aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 0.0 | 78.89% (450) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 0.0 | 76.61% (449) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4207 | - | 1e-162 | 65.39% (445) | 4-aminobutyrate aminotransferase |
| M. marinum M | MMAR_2118 | gabT | 0.0 | 76.22% (450) | 4-aminobutyrate aminotransferase GabT |
| M. avium 104 | MAV_3470 | gabT | 0.0 | 76.67% (450) | 4-aminobutyrate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_2959 | gabT | 0.0 | 84.38% (448) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 6e-42 | 32.36% (411) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1723 | gabT | 0.0 | 75.78% (450) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_2581 | - | 0.0 | 91.11% (450) | 4-aminobutyrate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3818|M.gilvum_PYR-GCK ----MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAARAF
Mvan_2581|M.vanbaalenii_PYR-1 ----MSALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAARAF
MSMEG_2959|M.smegmatis_MC2_155 ----MSHPEQSRHLATAIPGPRSQALIDRKGTAVARGVGTTMPVYAVRAG
Mb2620|M.bovis_AF2122/97 ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
Rv2589|M.tuberculosis_H37Rv ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
MLBr_00485|M.leprae_Br4923 ----MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAA
MAV_3470|M.avium_104 ----MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAG
MMAR_2118|M.marinum_M ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MUL_1723|M.ulcerans_Agy99 ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MAB_4207|M.abscessus_ATCC_1997 MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAVDAD
TH_3529|M.thermoresistible__bu -----------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALVSGD
:.*. . .* : *: . .
Mflv_3818|M.gilvum_PYR-GCK GGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCFMVT
Mvan_2581|M.vanbaalenii_PYR-1 GGIVEDVDGNRLIDLGSGIAVTTIGNASPKVVERAAEQLHKFTHTCFMVT
MSMEG_2959|M.smegmatis_MC2_155 GGIVEDVDGNRLIDLGSGIAVTTVGNSAPKVVEAVRSQVGDFTHTCFMVT
Mb2620|M.bovis_AF2122/97 GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
Rv2589|M.tuberculosis_H37Rv GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
MLBr_00485|M.leprae_Br4923 GGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIIT
MAV_3470|M.avium_104 GGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVT
MMAR_2118|M.marinum_M GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVT
MUL_1723|M.ulcerans_Agy99 GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVI
MAB_4207|M.abscessus_ATCC_1997 GGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCFMVT
TH_3529|M.thermoresistible__bu GAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSNLYA
*.:: *.**: :** .****. :* * * * : **. :
Mflv_3818|M.gilvum_PYR-GCK PYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFTRKQAV
Mvan_2581|M.vanbaalenii_PYR-1 PYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYTRKQAV
MSMEG_2959|M.smegmatis_MC2_155 PYEGYVAVCEQLNRLTPVRGDKRSALFNSGSEAVENAVKIARSHTHKPAV
Mb2620|M.bovis_AF2122/97 PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAV
Rv2589|M.tuberculosis_H37Rv PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAV
MLBr_00485|M.leprae_Br4923 PYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRKPAV
MAV_3470|M.avium_104 PYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRKPAV
MMAR_2118|M.marinum_M PYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRKQAV
MUL_1723|M.ulcerans_Agy99 PYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRKQAV
MAB_4207|M.abscessus_ATCC_1997 PYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLATGRPAV
TH_3529|M.thermoresistible__bu TEPGVALAEALVGHLG---APARVFFCNSGAEANEVAFKISR-LTGRTKV
. . . :. : * : ***:** * :.*::* * : *
Mflv_3818|M.gilvum_PYR-GCK VSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDAEFG
Mvan_2581|M.vanbaalenii_PYR-1 VSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPFRDAEFG
MSMEG_2959|M.smegmatis_MC2_155 VAFDHAYHGRTNLTMALTAKVMPYKDGFGPFAPEIYRAPLSYPFRDAEFG
Mb2620|M.bovis_AF2122/97 VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLD
Rv2589|M.tuberculosis_H37Rv VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLD
MLBr_00485|M.leprae_Br4923 VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLN
MAV_3470|M.avium_104 VAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDGLLD
MMAR_2118|M.marinum_M VAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDNLLD
MUL_1723|M.ulcerans_Agy99 VAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDNLLD
MAB_4207|M.abscessus_ATCC_1997 VAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPLRD----
TH_3529|M.thermoresistible__bu VAAEGGFHGRTMGALALTGQPSKREP-FEPLPGDVIHVPYG---------
*: : .:**** ::***.: : * *:. :: : * .
Mflv_3818|M.gilvum_PYR-GCK GKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAEGFL
Mvan_2581|M.vanbaalenii_PYR-1 -KELATDGELAARRAITVIDKQVGADNLAAVIIEPIQGEGGFIVPAEGFL
MSMEG_2959|M.smegmatis_MC2_155 -KELATDGELAAKRAITVIDKQIGADNLAAVVIEPIQGEGGFIVPADGFL
Mb2620|M.bovis_AF2122/97 -KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFL
Rv2589|M.tuberculosis_H37Rv -KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFL
MLBr_00485|M.leprae_Br4923 -KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAEGFL
MAV_3470|M.avium_104 -KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAEGFL
MMAR_2118|M.marinum_M -KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPADGFL
MUL_1723|M.ulcerans_Agy99 -KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPADGFL
MAB_4207|M.abscessus_ATCC_1997 --EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIVPAPGFL
TH_3529|M.thermoresistible__bu -------DAGALERAV--------DDTTAAVFLEPIMGEGGVVVPPAGYL
. * **: **:.:*** ****.:**. *:*
Mflv_3818|M.gilvum_PYR-GCK PTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDLIVTAKG
Mvan_2581|M.vanbaalenii_PYR-1 PTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG---IVPDLIVTAKG
MSMEG_2959|M.smegmatis_MC2_155 PTLLDWCRKNDVVFIADEVQTGFARTGAMFACEHEG---IDPDLIVTAKG
Mb2620|M.bovis_AF2122/97 PALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKG
Rv2589|M.tuberculosis_H37Rv PALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKG
MLBr_00485|M.leprae_Br4923 ATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICTAKG
MAV_3470|M.avium_104 PTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICTAKA
MMAR_2118|M.marinum_M PALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVTAKG
MUL_1723|M.ulcerans_Agy99 PALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVTAKG
MAB_4207|M.abscessus_ATCC_1997 ATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDIVTMAKG
TH_3529|M.thermoresistible__bu AAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVVTLAKG
.: : .::: ******:.*:*: ** :*:. : **:: **.
Mflv_3818|M.gilvum_PYR-GCK IAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIESDN
Mvan_2581|M.vanbaalenii_PYR-1 IADGMPLSAVTGRAEIMDAPHVSGLGGTYGGNPVACAAALATIETIESDG
MSMEG_2959|M.smegmatis_MC2_155 IAGGLPLSAVTGRAEIMDSPHVSGLGGTYGGNPIACAAALATIETIESEG
Mb2620|M.bovis_AF2122/97 IADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG
Rv2589|M.tuberculosis_H37Rv IADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG
MLBr_00485|M.leprae_Br4923 IADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIENDG
MAV_3470|M.avium_104 IADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIESDG
MMAR_2118|M.marinum_M IADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIERDG
MUL_1723|M.ulcerans_Agy99 IADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIERDG
MAB_4207|M.abscessus_ATCC_1997 IAGGMPLSAVTGRAELMDAVYAGGLGGTYGGNPVTCAAAVAALGVMRELD
TH_3529|M.thermoresistible__bu LGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNPVCTAAAVAVLGALAEGD
:..*:*:.* . . : . *.*:****: ***:*.: .: .
Mflv_3818|M.gilvum_PYR-GCK LVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVELVKSGTLEPDP
Mvan_2581|M.vanbaalenii_PYR-1 LVARAAQIETLMKDKLGRLQAEDDRIGDVRGRGAMIAVELVKPGTLEPDP
MSMEG_2959|M.smegmatis_MC2_155 LVARAQQIEKIMKDRLGRLQAEDDRIGDVRGRGAMIAMELVKAGTTEPDA
Mb2620|M.bovis_AF2122/97 LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDA
Rv2589|M.tuberculosis_H37Rv LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDA
MLBr_00485|M.leprae_Br4923 LIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGTAEPDP
MAV_3470|M.avium_104 LIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAEPDK
MMAR_2118|M.marinum_M MVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAEPDA
MUL_1723|M.ulcerans_Agy99 MVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAEPDA
MAB_4207|M.abscessus_ATCC_1997 LPARARAIEASVTSRLSALAEEVDIIGEVRGRGAMLAIEIVKPGTLEPDA
TH_3529|M.thermoresistible__bu LINRADVLGKKLSHGIEELRHP--LVDHVRGRGLLCGVVLNAP-------
: ** : : : : :..***** : .: : .
Mflv_3818|M.gilvum_PYR-GCK ELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPLAISDDLLLEGLDILELI
Mvan_2581|M.vanbaalenii_PYR-1 ELTKNLLAAAHRAGVIVLSCGTFGNVLRFLPPLAISDELLLEGLDVLELI
MSMEG_2959|M.smegmatis_MC2_155 DLTKALCAGAHAAGVIVLSCGTYGNVVRFLPPLSIGDDLLNEGLDVLEEV
Mb2620|M.bovis_AF2122/97 GLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAI
Rv2589|M.tuberculosis_H37Rv GLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAI
MLBr_00485|M.leprae_Br4923 ELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLDILSRI
MAV_3470|M.avium_104 DLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGIDILGGL
MMAR_2118|M.marinum_M ALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDILCQI
MUL_1723|M.ulcerans_Agy99 ALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDILCQI
MAB_4207|M.abscessus_ATCC_1997 ALTKSIAAEALSQGVLILTCGTFGNVIRLLPPLVIGDDLLDEGITALSDI
TH_3529|M.thermoresistible__bu ---QAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFLAALPGV
. . * .. .* . :::*: *** * : : * : : :
Mflv_3818|M.gilvum_PYR-GCK LRDL----
Mvan_2581|M.vanbaalenii_PYR-1 LRDL----
MSMEG_2959|M.smegmatis_MC2_155 LRGA----
Mb2620|M.bovis_AF2122/97 LADL----
Rv2589|M.tuberculosis_H37Rv LADL----
MLBr_00485|M.leprae_Br4923 LGDF----
MAV_3470|M.avium_104 LADL----
MMAR_2118|M.marinum_M LADL----
MUL_1723|M.ulcerans_Agy99 LADL----
MAB_4207|M.abscessus_ATCC_1997 IRAKASHQ
TH_3529|M.thermoresistible__bu LDTAKEAS
: