For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSSEPVRIVLVDDHEMVIEGLKAMLAAFADRVCVVGQSVGADQVMGVVTDLDPDIVLCDVRMQGSSGLDV CQQLRRRDPDRKIVMLSVYDDEQYLFQAMRVGASGYLLKSISSEDLVEQLESVHSGKTAIDPTMAARAVE WPGARQGLTQRESEILALVVNGLSNRAIAAKLIIGDETVKTHLSSIYRKLGVSDRTAAVATALREGIFQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5014 | - | - | 100% (209) | two component LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3847 | - | 9e-28 | 32.50% (200) | two component LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0730 | - | 3e-25 | 31.55% (206) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 7e-29 | 33.33% (204) | two component transcriptional regulatory protein DevR |
| M. tuberculosis H37Rv | Rv3133c | devR | 7e-29 | 33.33% (204) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-10 | 31.90% (116) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 2e-30 | 33.82% (207) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_3480 | - | 2e-29 | 32.21% (208) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_5280 | - | 2e-28 | 33.65% (211) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_1494 | - | 9e-89 | 76.50% (217) | transcriptional regulatory protein DegU |
| M. thermoresistible (build 8) | TH_3184 | - | 7e-89 | 76.74% (215) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_2423 | devR | 5e-29 | 32.84% (204) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 1e-100 | 84.86% (218) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5014|M.gilvum_PYR-GCK ----MSSEPVRIVLVDDHEMVIEGLKAMLAAFADRVCVVGQSVGADQVMG
Mvan_1358|M.vanbaalenii_PYR-1 ---METASPVRIVLVDDHEMVIEGLKAMLAAFGSRVTVVGQAVGADRVLG
MSMEG_1494|M.smegmatis_MC2_155 ---MAPSSPVRLVLVDDHEMVIEGLKAMLAAFSDRVLVVGQAVGAEKAVS
TH_3184|M.thermoresistible__bu MEPVAAPSPVRIVLVDDHEMVIEGLKAMLAAFEDRVCVVGHAVGAERAVE
Mb3157c|M.bovis_AF2122/97 --------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVAEAMA
Rv3133c|M.tuberculosis_H37Rv --------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVAEAMA
MUL_2423|M.ulcerans_Agy99 --------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVSEAMA
MMAR_3480|M.marinum_M --------MVKVFLVDDHEVVRRGLVDLLGSDPD-LEIIGEAGSVSEAMA
MAB_3891c|M.abscessus_ATCC_199 --------MITVFLVDDHEVVRRGLADLLEEEAD-FSVIGQASSVAEAMA
MAV_5280|M.avium_104 --MTDPAPEITVLLVDDQDLVRSGLRRILRRKDG-FVIVAECADGDEVPA
MLBr_00773|M.leprae_Br4923 ----MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDG---TQALT
:.:***. : * :* ::.. ..
Mflv_5014|M.gilvum_PYR-GCK VVTDLDPDIVLCDVRMQGSSGLDVCQQLRRRDPDRKIVMLSVYDDEQYLF
Mvan_1358|M.vanbaalenii_PYR-1 VVTELDPDIVLCDVRMQGSSGLDVCQQLRERDPDRKVVMLSVYDDEQYLF
MSMEG_1494|M.smegmatis_MC2_155 VVEELDPDIVLCDVRMQGVSGLDLCQTLLERNPERKVVMLSVYDDEQYLF
TH_3184|M.thermoresistible__bu VVAELDPDIVLCDVRMQNTSGLDLCLTLREQAPHRKVVMLSVYDDEQYLY
Mb3157c|M.bovis_AF2122/97 RVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAML
Rv3133c|M.tuberculosis_H37Rv RVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAML
MUL_2423|M.ulcerans_Agy99 RIPAANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAML
MMAR_3480|M.marinum_M RIPALQPDVAVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSDEAML
MAB_3891c|M.abscessus_ATCC_199 RIPALQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAML
MAV_5280|M.avium_104 AVAAHRPDVVVMDLRMRRVDGIEATRRLGGRPP---VLALTTFNEDELLS
MLBr_00773|M.leprae_Br4923 AVRELRPDLVLLDLMLPGMNGIDVCRVLR-ADSGVPIVMLTAKTDTVDVV
: **:.: *: : .*:: * . : *: . :
Mflv_5014|M.gilvum_PYR-GCK QAMRVGASGYLLKSISSEDLVEQLESVHSGKTAIDPTMAARAVE------
Mvan_1358|M.vanbaalenii_PYR-1 QALRVGASGYLLKSISSEELVKQLESVHGGQTAIDPSMAARAADTAARMQ
MSMEG_1494|M.smegmatis_MC2_155 QALRVGAAGYLLKSISSDDLVHQLEFAHSGETAIDPVMAARAAGTAARLQ
TH_3184|M.thermoresistible__bu QALRVGASGYLLKSISSDELVRQLEMVHRGQTALDPGMAARAVDTAARLQ
Mb3157c|M.bovis_AF2122/97 DAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDN-RAAAALMAKLRGA
Rv3133c|M.tuberculosis_H37Rv DAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDN-RAAAALMAKLRGA
MUL_2423|M.ulcerans_Agy99 DAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDN-RAAAALMSRLRGV
MMAR_3480|M.marinum_M EAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDN-RAAAALMAKLRGG
MAB_3891c|M.abscessus_ATCC_199 DAIMAGAGGYVIKDIKGMELISAVRTVGAGRSLLDN-RAAAALMNRLRAA
MAV_5280|M.avium_104 GALRAGAAGFVLKDSSAEELIRAVRAVARGEGYLDP-AVTSRVLTTYRKA
MLBr_00773|M.leprae_Br4923 LGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVDIDVPA
.: ** .:::* . :* :. . :
Mflv_5014|M.gilvum_PYR-GCK ----WPGARQGLTQRESEILALVVNG---------LSNRAIAAKLIIGDE
Mvan_1358|M.vanbaalenii_PYR-1 RDEFWPGARRGLTQRESEILALVVNG---------LSNRAIAAKLIIGDE
MSMEG_1494|M.smegmatis_MC2_155 RDEFWPGARQGLTQRESEILSFVVAG---------LSNRGIANKLVIGEE
TH_3184|M.thermoresistible__bu RDEFWPGARHGLTQRESEILSYVVNG---------LSNRGIAAKLVIGDE
Mb3157c|M.bovis_AF2122/97 AEKQD--PLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEK
Rv3133c|M.tuberculosis_H37Rv AEKQD--PLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEK
MUL_2423|M.ulcerans_Agy99 VERPD--PLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEK
MMAR_3480|M.marinum_M AEQKD--PLSGLTEQERTLLGHLSEG---------LTNRQIAARMFLAEK
MAB_3891c|M.abscessus_ATCC_199 ADNPS--PLAGLTAQERTLLELIGEG---------LTNRQIAERMFLAEK
MAV_5280|M.avium_104 APGPHGAAIAELTTRERDVLTLIGKG---------LSNSEIADELCISGV
MLBr_00773|M.leprae_Br4923 HKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTR
** * :* : * : . .
Mflv_5014|M.gilvum_PYR-GCK TVKTHLSSIYRKLGVSDRTAAVATALREGIFQ------
Mvan_1358|M.vanbaalenii_PYR-1 TVKTHLSSIYRKLGVSDRTAAAATALREGIYQ------
MSMEG_1494|M.smegmatis_MC2_155 TVKTHLRSIYRKLGVSDRAGAVATALREGIYQ------
TH_3184|M.thermoresistible__bu TVKSHLRSIYRKLGVSDRAAAVATALREGIYQ------
Mb3157c|M.bovis_AF2122/97 TVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv TVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
MUL_2423|M.ulcerans_Agy99 TVKNYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR-
MMAR_3480|M.marinum_M TVKNYVSRLLAKLGMERRTQAAVFASRLGQGTRPVQGD
MAB_3891c|M.abscessus_ATCC_199 TVKNYVSRLLTKLDLERRTQVAVLATKLARENQGLHG-
MAV_5280|M.avium_104 TVKSHIGRIFGKLDLRDRAAAIVYAYDNGIVAPR----
MLBr_00773|M.leprae_Br4923 LVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP--
*: :: : *: . . . :