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ADDRNLPAFRRHGRQEGDRTDAEFDELIAARNQMDHLVRAIVAIGSDLDFSVTLERIVTAARELSGARYA GLGIRAAGGNLVSFVESGDEFDVAALAGLPIDGGLRIDDLRDHPEITDLQALNRPIRALLAIPVTVRGAD FGSLYLADDRPGRVFSDAQESAVRALATAAAAAIDNARLFEREREAARWTKASREITTALLSGDPQTGPL QLIVNRALELAGAEQAILLVPLEPDVPAEDVDTLIVAATAGRYSSEVIGRQVPMAGSTTGGVARRGLPMI TDSFQYPIEGFTDVGERSAIVMPLIVDDAVLGVIAVARRPNQPAFDEDYLELVSDFARHASIALALAAGR EHALNRQLAQADSVSEAMAGAAEELRRLWRARRVLAVTFPTRSEAADVEPVVVSAGEHTTWRELPDGIRQ ILLSMRRGDLLTPNAAEPGTAGIAVQHPEGILVVWIELAEHRSFTLEDQTLLTVLAGRLSAGLQRVHQVD QQRETALALQHAILGPAHLPPGFTVRYQAASRPLQVGGDWYDVVDLDDGRIALIVGDCVGHGLAAATVMG QVRSACRALLLENPSPGAALSGMDRFAARLPGAQCTTAVVMVLDPASGEIAYSSAGHPPPLVVHADGEVE TFDDAHTIALGLRLNWVRPETRRTLEVGSTLVLYTDGLVERRRIPLEEGISRATDVVVEHRAAPLDDLAN AIMSELAPSVGYQDDVALLLYRHPAPLELTFPAHADHLAPTRTALRRWLSGAKVEQGRVMEVLVAAGEAV ANAIEHGHRHGPPGTVRLRATALVDLVELIITDSGSWKPPSAIPDTYRGRGIGIMRGLMQDVTIAHDSDG TTIHLYARIS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4521 | - | - | 100% (851) | putative GAF sensor protein |
M. gilvum PYR-GCK | Mflv_4423 | - | e-170 | 60.60% (500) | multi-sensor signal transduction histidine kinase |
M. gilvum PYR-GCK | Mflv_3844 | - | 5e-44 | 35.42% (336) | GAF sensor signal transduction histidine kinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2052c | - | 1e-49 | 33.90% (354) | histidine kinase response regulator |
M. tuberculosis H37Rv | Rv2027c | - | 1e-49 | 33.90% (354) | histidine kinase response regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3890c | - | 2e-43 | 34.10% (349) | histidine kinase response regulator |
M. marinum M | MMAR_5186 | - | 1e-95 | 40.08% (514) | sensor-component of a two-component regulator |
M. avium 104 | MAV_2108 | - | 0.0 | 70.72% (830) | stage II sporulation protein E (SpoIIE) |
M. smegmatis MC2 155 | MSMEG_3941 | - | 8e-57 | 42.48% (339) | GAF family protein |
M. thermoresistible (build 8) | TH_2781 | - | 3e-95 | 39.42% (515) | PUTATIVE stage II sporulation protein E (SpoIIE) |
M. ulcerans Agy99 | MUL_3853 | rsbU | 8e-52 | 33.25% (400) | regulator of sigma subunit, anti-anti-sigma factor RsbU |
M. vanbaalenii PYR-1 | Mvan_3797 | - | 0.0 | 74.58% (826) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2052c|M.bovis_AF2122/97 MTHPDRANVNPGSPPVRETLSQLRLRELLLEVQDRIEQIVEG-RDRLDGL Rv2027c|M.tuberculosis_H37Rv MTHPDRANVNPGSPPLRETLSQLRLRELLLEVQDRIEQIVEG-RDRLDGL MAB_3890c|M.abscessus_ATCC_199 MVEDVGAQPNR----VTAELAHLQLRELLAEVQGRIEQIVDGTRGRMDAL MSMEG_3941|M.smegmatis_MC2_155 ------------------------------MGQSHTDDSPEAVEVRMAAL MAV_2108|M.avium_104 --------------------------------MHTRLDELMAARDQLEQL Mvan_3797|M.vanbaalenii_PYR-1 ------------------------------------MDELVAARDQMERL Mflv_4521|M.gilvum_PYR-GCK ------------MADDRNLPAFRRHGRQEGDRTDAEFDELIAARNQMDHL MMAR_5186|M.marinum_M ----------------------------------MTETGDFGAVDAFQTQ TH_2781|M.thermoresistible__bu ------------------------------------MSPDFGAR------ MUL_3853|M.ulcerans_Agy99 --------------------------MLLLDLLRQRTYSFVRSVHRRDGY Mb2052c|M.bovis_AF2122/97 IDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYE Rv2027c|M.tuberculosis_H37Rv IDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYE MAB_3890c|M.abscessus_ATCC_199 LDAVMAVSSGLELDATLREIVCAASELVSARYGALGVVGSDEKLAEFVYE MSMEG_3941|M.smegmatis_MC2_155 LQDMASLDAGLEPESTLHGILDAIMRVSGACYGAAGLCAPDGTPATFLQA MAV_2108|M.avium_104 VRVIAEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGGLLSFVHA Mvan_3797|M.vanbaalenii_PYR-1 VRVIVAIGADLDLDVTLRRIVTGARELSGARYGALGIRGADGTWASFVCD Mflv_4521|M.gilvum_PYR-GCK VRAIVAIGSDLDFSVTLERIVTAARELSGARYAGLGIRAAGGNLVSFVES MMAR_5186|M.marinum_M YADALRAYLDTRDENSLAVGHEFGRRALQEQISILDIIENHFRLLDEISP TH_2781|M.thermoresistible__bu YAAALAAYLEDSSERRLAVAHDLGRQALLGRISVLQIVEDHVRLVDELSR MUL_3853|M.ulcerans_Agy99 MAAEMDWDKNVGTANTVRRIFENVPTMLVGLEGPEHRFVAANAAYRRFSP : . . Mb2052c|M.bovis_AF2122/97 GIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPP Rv2027c|M.tuberculosis_H37Rv GIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPP MAB_3890c|M.abscessus_ATCC_199 GIDEATRDLIGPLPTGHGVLGVVIDEAKPLRLRDIAAHPASVGFPANHPP MSMEG_3941|M.smegmatis_MC2_155 G---ALAQAVPDSPD-RDMLGFLRNRTGPLRIDGLARSAAEVGLPELLPP MAV_2108|M.avium_104 GLDADTARQLGELAVGDGLR-----------IDDVSVDPRSAHLSAHDPP Mvan_3797|M.vanbaalenii_PYR-1 GMEEDAARALGGLAAGEGIR-----------IDDLTGYSGVAGLRSQKTP Mflv_4521|M.gilvum_PYR-GCK GDEFDVA-ALAGLPIDGGLR-----------IDDLRDHPEITDLQALNRP MMAR_5186|M.marinum_M NPGSDRSVALEFLLQTLAAL-----------------DVATRGFLDGTKR TH_2781|M.thermoresistible__bu RQPVDTDTALQFLLQALAAV-----------------DVAVRGYLEGTRR MUL_3853|M.ulcerans_Agy99 TFTAVGQPAREVYPELESQQ-----------IYHMLDRVYETGEPQSGAE Mb2052c|M.bovis_AF2122/97 MRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVD Rv2027c|M.tuberculosis_H37Rv MRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVD MAB_3890c|M.abscessus_ATCC_199 MRTFLGVPVQVRGEVFGRLYLTEKLDGQEFTEDDEVVVRALAGAAGIAIE MSMEG_3941|M.smegmatis_MC2_155 MRAVLGVPLVSHGEVLGSLYVADSRAGFEFSDAHVGVVEVLATVAADVVH MAV_2108|M.avium_104 LRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAMATAAAAAID Mvan_3797|M.vanbaalenii_PYR-1 MRALLGVPITVRGADFGALYLADDQPDRVFSDSQEGAVRALATAAAAAID Mflv_4521|M.gilvum_PYR-GCK IRALLAIPVTVRGADFGSLYLADDRPGRVFSDAQESAVRALATAAAAAID MMAR_5186|M.marinum_M YEEQRARAEDLAHRDKFRSALVNSLQEGFFVADDEGAVIDMNSAFAEILG TH_2781|M.thermoresistible__bu YEQQRARAEGLAGRDTFRSALVNAMQEAFFVMDRTGSVIDINEAFAEITG MUL_3853|M.ulcerans_Agy99 WRLQADFDGSGIDERYFDFLVTPRRREDGSIEGVQILFDDVTTRVRARLA . :. . : Mb2052c|M.bovis_AF2122/97 NARLFEESRTREAWIEATRDIGTQMLAGAD--PAMVFRLIAEEALTLMAG Rv2027c|M.tuberculosis_H37Rv NARLFEESRTREAWIEATRDIGTQMLAGAD--PAMVFRLIAEEALTLMAG MAB_3890c|M.abscessus_ATCC_199 NARLYQHARRREQWQRATADITAELLGGVD--PGKALHLVASSAALLAEA MSMEG_3941|M.smegmatis_MC2_155 SVWHLAKVRTVARWVSASREITMALLGMSGG-EDAPLRLIVGRAAELTVA MAV_2108|M.avium_104 NARLFERERESAKWTKASREITTALLSGDP--QTGPLQLIVNRALELAGA Mvan_3797|M.vanbaalenii_PYR-1 NARLFERERESAKWTKASREITTALLSGDP--QTGPLQLIVNLALELADA Mflv_4521|M.gilvum_PYR-GCK NARLFEREREAARWTKASREITTALLSGDP--QTGPLQLIVNRALELAGA MMAR_5186|M.marinum_M YPPEGLPYRWPHPWLVDRKSAAQQQERVRHEGSADYETPVRHQDGHLSWV TH_2781|M.thermoresistible__bu YDGHDLPYRWPHPWVVDEPRADEDLLELLQHGRVQLERQIRHRSGHLAWV MUL_3853|M.ulcerans_Agy99 AEARVEELSERYRHLRDSAIVMQQALLAPS-------VPVVSGPDIAAQY : Mb2052c|M.bovis_AF2122/97 AATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVF Rv2027c|M.tuberculosis_H37Rv AATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVF MAB_3890c|M.abscessus_ATCC_199 DFAFIALPAGDEE---DTAELVVAVCEGKGAEVLNDKLIPIDGSTSGSTF MSMEG_3941|M.smegmatis_MC2_155 SQAAILVPSEADRAPEEVRSLTVAVAAGARADEVEGQQVPVSGSTSGRVF MAV_2108|M.avium_104 EQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVA Mvan_3797|M.vanbaalenii_PYR-1 EQAILLVPGEPDLPGDEADTLVVAATAGRYASEVIGRQVPMDGSTTGGVA Mflv_4521|M.gilvum_PYR-GCK EQAILLVPLEPDVPAEDVDTLIVAATAGRYSSEVIGRQVPMAGSTTGGVA MMAR_5186|M.marinum_M AVSINAVRGSGSDRDVYVGTVRDITAERAFAARESAVLRLATSVSVAKSV TH_2781|M.thermoresistible__bu AISVNVVNPNGT---AFVGTMRDITAAHKAAARESALTRLATAAGVATSV MUL_3853|M.ulcerans_Agy99 LVAAQDTAAGGDWFDAVALGDRLVLIVGDVVGHGVEAAAVMSQLRTALRL : . . Mb2052c|M.bovis_AF2122/97 HDRTPRRFDRLDLAVDG--PVEPGPALVLPLRAADTVAGVLVALRSADEQ Rv2027c|M.tuberculosis_H37Rv HDRTPRRFDRLDLAVDG--PVEPGPALVLPLRAADTVAGVLVALRSADEQ MAB_3890c|M.abscessus_ATCC_199 IDHEPRNVGRLAVNLAEGTDLAFGPALVLPLGGGESTAGVLILLRTVGAI MSMEG_3941|M.smegmatis_MC2_155 RTGESTMTDGFRYPITSFTDQGRRPAIVVPLRSATNNLGVIAVARDADDP MAV_2108|M.avium_104 RRGLPLITDSFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQP Mvan_3797|M.vanbaalenii_PYR-1 RRGLPLITDSFQYPIEGFTDAGERSAIVMPLIADEAVLGVIAVARRPHQP Mflv_4521|M.gilvum_PYR-GCK RRGLPMITDSFQYPIEGFTDVGERSAIVMPLIVDDAVLGVIAVARRPNQP MMAR_5186|M.marinum_M SEVLSITLEECRTAVDV-------QRVVAVMWPPSDGEPTVQVAGEPAES TH_2781|M.thermoresistible__bu SEVLSIMLDECRPAIDS-------RRVIAVTWAREDAEPTIQVVGDPPAS MUL_3853|M.ulcerans_Agy99 QIAAGRSIGEALEALDAFHEHVPGSNSATLCVGSLDFTTGEFQYCTAGHP : Mb2052c|M.bovis_AF2122/97 PFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDRIARDLHDH Rv2027c|M.tuberculosis_H37Rv PFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDRIARDLHDH MAB_3890c|M.abscessus_ATCC_199 AFDEEQLDMAASFAGQAALALEQAEVRLAKH-ELDVLADRDRIARDLHDH MSMEG_3941|M.smegmatis_MC2_155 PFDVDEMAIMEDFAHHAAVALTLCRANEQAR-QLTVLSDRERIARDLHDH MAV_2108|M.avium_104 PFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVDEAVRAAAE Mvan_3797|M.vanbaalenii_PYR-1 PFDNDYLELVSDFARHAAIALALAAGREHALNQELAQADSVDAALHAAAE Mflv_4521|M.gilvum_PYR-GCK AFDEDYLELVSDFARHASIALALAAGREHALNRQLAQADSVSEAMAGAAE MMAR_5186|M.marinum_M SWRALDPQLRETFLGARAQLPLTARPIEWPDSPGRAQG-LVAVLSGTADV TH_2781|M.thermoresistible__bu TWADLDESLRTTLLAARDWPPLTVQPVSDAG-QNTSRG-IVAVLSGTPAT MUL_3853|M.ulcerans_Agy99 PPLVVTAEAKARYLEPSGAGPLGSDTGFPVRTELIGVGDVVLLYTDGLIE . Mb2052c|M.bovis_AF2122/97 VIQRLFAVGLTLQGAAP--------------------------------- Rv2027c|M.tuberculosis_H37Rv VIQRLFAVGLTLQGAAP--------------------------------- MAB_3890c|M.abscessus_ATCC_199 VIQRLFAVGLAMQSTHR--------------------------------- MSMEG_3941|M.smegmatis_MC2_155 VIQRLFLAGMDLQGTIA--------------------------------- MAV_2108|M.avium_104 ELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQ Mvan_3797|M.vanbaalenii_PYR-1 ELRRLWRARRVLAVTFPTHGDSVESA---PKVVAVGEDTHWADLSAPTRL Mflv_4521|M.gilvum_PYR-GCK ELRRLWRARRVLAVTFPTRSEAADVE---PVVVSAGEHTTWRELPDGIRQ MMAR_5186|M.marinum_M ALWLELGAPRWVT--AE--------------------------------- TH_2781|M.thermoresistible__bu VLWLEHRVPRPVG--ID--------------------------------- MUL_3853|M.ulcerans_Agy99 RPGRPLGASTAEFADLA--------------------------------- . Mb2052c|M.bovis_AF2122/97 ------------------------------------------------RA Rv2027c|M.tuberculosis_H37Rv ------------------------------------------------RA MAB_3890c|M.abscessus_ATCC_199 ------------------------------------------------RS MSMEG_3941|M.smegmatis_MC2_155 ------------------------------------------------RT MAV_2108|M.avium_104 ALGSLRDGDLLTPNTTQPGTAGIALQHPDGVLVVWIDLTDERSFTLEDQT Mvan_3797|M.vanbaalenii_PYR-1 TLSALRDGDLLTPNTAQPGTAGIAMQHPEGILVVWLDLTDQRSFTLEDQT Mflv_4521|M.gilvum_PYR-GCK ILLSMRRGDLLTPNAAEPGTAGIAVQHPEGILVVWIELAEHRSFTLEDQT MMAR_5186|M.marinum_M -----------------------------------------------DRL TH_2781|M.thermoresistible__bu -----------------------------------------------GRR MUL_3853|M.ulcerans_Agy99 -------------------------------------------------- Mb2052c|M.bovis_AF2122/97 RVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGP---SRATGLRHRLDKV Rv2027c|M.tuberculosis_H37Rv RVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGP---SRATGLRHRLDKV MAB_3890c|M.abscessus_ATCC_199 VDPTVAARLADHIDQLHEVIQEIRTAIFDLHTN------DESLRATLRST MSMEG_3941|M.smegmatis_MC2_155 KSDLLKERLSRTVDDLQSIIDEIRTAIFDLQSPA---ASAMSFRQRIQAA MAV_2108|M.avium_104 LLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNGFAVRYQAA Mvan_3797|M.vanbaalenii_PYR-1 LLTVLAGRLSQGLQRVHRVDQQRETALALQHAILGPADLPHGFAVRYQAA Mflv_4521|M.gilvum_PYR-GCK LLTVLAGRLSAGLQRVHQVDQQRETALALQHAILGPAHLPPGFTVRYQAA MMAR_5186|M.marinum_M LVTVLVGHLSLAIGHVRQFESARETSLTLQRAMLPPVKPPPGFAVRYEPA TH_2781|M.thermoresistible__bu LINALVGHVSLAVQHVRRFEIARESSLTLQRAMLPDIVPPPGFAVRYEPA MUL_3853|M.ulcerans_Agy99 -ANITSGGGFVIDAQSRPIDRLCSETLELLLRSTGYNDDITLLAVQRRAP : . :: : Mb2052c|M.bovis_AF2122/97 IDQLAIP-ALHTTVQYTG---PLSVVDTVLANHAEAVLREAVSNAVRHAN Rv2027c|M.tuberculosis_H37Rv IDQLAIP-ALHTTVQYTG---PLSVVDTVLANHAEAVLREAVSNAVRHAN MAB_3890c|M.abscessus_ATCC_199 INELTAETGLRVSVRMSG---PLDVVPASTSGDAEAVVREAVSNVVRHAR MSMEG_3941|M.smegmatis_MC2_155 VAAVTDNSPLATTVRISG---PIVAVDPALADDAEAVIVEAISNAVRHSG MAV_2108|M.avium_104 TRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALL Mvan_3797|M.vanbaalenii_PYR-1 SRPLQVGGDWYDVVDLDDGRIAMIVGDCVGHGLPAATVMGQVRSACRALL Mflv_4521|M.gilvum_PYR-GCK SRPLQVGGDWYDVVDLDDGRIALIVGDCVGHGLAAATVMGQVRSACRALL MMAR_5186|M.marinum_M VPPLEIGGDWYDVLPIGEHRIGIVVGDCVGRGLPAAAIMGQLRSSARALL TH_2781|M.thermoresistible__bu VRPLEIGGDWYDVLPLDDHQIGIIVGDCVGRGLPAAAVMGQLRSSARALL MUL_3853|M.ulcerans_Agy99 TPPLNITEDATIHAARAIRSRLRQWLSEIGADSGDISDIVHAISEFVENA : . . Mb2052c|M.bovis_AF2122/97 ATSLAINVSVEDDVRVEVVDDGVGISGDITES-GLRNLRQRADDAGGEFT Rv2027c|M.tuberculosis_H37Rv ATSLAINVSVEDDVRVEVVDDGVGISGDITES-GLRNLRQRADDAGGEFT MAB_3890c|M.abscessus_ATCC_199 ARELSVTVSVDDELVIEVVDDGIGIPDVVARS-GLSGLANRAAQSGGTFS MSMEG_3941|M.smegmatis_MC2_155 ATSVTISIEVSDRLDIEVVDNGRGIPANTARCSGLANLKARAQQAGGSCQ MAV_2108|M.avium_104 IENPSPAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVYSSAGHPPP Mvan_3797|M.vanbaalenii_PYR-1 FDNPSPAAALAGMDRFAARLPGAQCATAVCAVLDPATGELVYSSAGHPPP Mflv_4521|M.gilvum_PYR-GCK LENPSPGAALSGMDRFAARLPGAQCTTAVVMVLDPASGEIAYSSAGHPPP MMAR_5186|M.marinum_M LTGAQPALLLEQLDAAASLIPDAYCTTVFLAILDTESGILDYSNAGHMPA TH_2781|M.thermoresistible__bu LSGAEPARLLENLDAVAALIPDAYCATVLLAVLDTESGTLRYSNAGHVPA MUL_3853|M.ulcerans_Agy99 VEHGYSTDVSDGLAVAAALGGDGKLRVAVIDHGTWKHHREGERGRGRGLA . * Mb2052c|M.bovis_AF2122/97 VENMPTG-------------GTLLRWSAPLR------------------- Rv2027c|M.tuberculosis_H37Rv VENMPTG-------------GTLLRWSAPLR------------------- MAB_3890c|M.abscessus_ATCC_199 VSAMDTG-------------GTRLVWSAPLP------------------- MSMEG_3941|M.smegmatis_MC2_155 ITSSAGS-------------GTHVRWSAPLSGA----------------- MAV_2108|M.avium_104 IVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVE Mvan_3797|M.vanbaalenii_PYR-1 ILMHADGSARLLEGAHTIALGLRVGWSRPEGRLSIPAGATLMLYTDGLVE Mflv_4521|M.gilvum_PYR-GCK LVVHADGEVETFDDAHTIALGLRLNWVRPETRRTLEVGSTLVLYTDGLVE MMAR_5186|M.marinum_M VLAEPKSGPVLLTDARSVPLAVRRVEPRPEATQVLPPGSTLLLFTDGLVE TH_2781|M.thermoresistible__bu LLAGPGPHATVLTDGASVPLGVQQNRPRPQVSRQLTPGSTLMLYTDGLVE MUL_3853|M.ulcerans_Agy99 MAEALVS-----------ETHVSHDGAGTTATVVHRLSRPAQFVTDPVVS : . Mb2052c|M.bovis_AF2122/97 -------------------------------------------------- Rv2027c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_3890c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3941|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2108|M.avium_104 RRRSPLDRGIYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLL Mvan_3797|M.vanbaalenii_PYR-1 RRRTLLEDGISRAAELLEGHRTSDLEDLADQIMSGLAPSVGYQDDVALLL Mflv_4521|M.gilvum_PYR-GCK RRRIPLEEGISRATDVVVEHRAAPLDDLANAIMSELAPSVGYQDDVALLL MMAR_5186|M.marinum_M RRYESIDEGLGRVADVVADSVMLPIDAVADAVLSQLAPTGGYDDDVAMVA TH_2781|M.thermoresistible__bu RRDSPIDTGMDRACQVLTAMLDAEPEAVADAMLDTLAPADGYDDDVAIVV MUL_3853|M.ulcerans_Agy99 RAPNRPAIDSEFASTVTESGHIVVRGDVDSNTAPTLDRQIAVESRSGIAS Mb2052c|M.bovis_AF2122/97 -------------------------------------------------- Rv2027c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_3890c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3941|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2108|M.avium_104 YRHPAP-LELNFPADVNQLAPARTALRNWLRRVRLDPEQTLNVLVAAGEA Mvan_3797|M.vanbaalenii_PYR-1 YRHPAP-LQLNFPADANHLAPARAALRSWLTSARVEPARVMDVLVAAGEA Mflv_4521|M.gilvum_PYR-GCK YRHPAP-LELTFPAHADHLAPTRTALRRWLSGAKVEQGRVMEVLVAAGEA MMAR_5186|M.marinum_M YRYQHGPLRIETSATPDQLVIVRRQLLSWLQAAEVPDEQAGDIVLVVSEA TH_2781|M.thermoresistible__bu YRHTFAPLRIELPATPDRLSEVRARLTGWLTAAGAPELLISDIVLAVNEA MUL_3853|M.ulcerans_Agy99 LTIDLSAVTHLGSAGVSALVTARDRAR----------------------- Mb2052c|M.bovis_AF2122/97 -------------------------------------------------- Rv2027c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_3890c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3941|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2108|M.avium_104 VANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRG Mvan_3797|M.vanbaalenii_PYR-1 LANAIEHGHRHTPDGTVSLRATALVDRVRLTVADTGSWKVPQPGRDSRRG Mflv_4521|M.gilvum_PYR-GCK VANAIEHGHRHGPPGTVRLRATALVDLVELIITDSGSWKPPSAIPDTYRG MMAR_5186|M.marinum_M CTNCIEHAYRGQSVGTMLLDVEAADWAIHARVVDSGSWKKPAADP-GNGG TH_2781|M.thermoresistible__bu CTNSVEHAYRDREPGPMQVYADLRDGQIMLQVRDFGTWKTPEPNP-RIRG MUL_3853|M.ulcerans_Agy99 -----KQGGRCVLMAPPGSPAHHVLSLVQIPVISGETENVFAED------ Mb2052c|M.bovis_AF2122/97 ------------------------------------- Rv2027c|M.tuberculosis_H37Rv ------------------------------------- MAB_3890c|M.abscessus_ATCC_199 ------------------------------------- MSMEG_3941|M.smegmatis_MC2_155 ------------------------------------- MAV_2108|M.avium_104 RGIPLMKSLMNDVDIRSDTGGTTVQLSARIT------ Mvan_3797|M.vanbaalenii_PYR-1 RGIALMRALMHDVEIDIGRSGTSVHLDTRID------ Mflv_4521|M.gilvum_PYR-GCK RGIGIMRGLMQDVTIAHDSDGTTIHLYARIS------ MMAR_5186|M.marinum_M RGMTLIRAISDEVEIDNSPGGTAIDMTFRLPSED--- TH_2781|M.thermoresistible__bu RGLPMMRAISADVQVDNTRSGTVVELTFTLSGQPALT MUL_3853|M.ulcerans_Agy99 -------------------------------------