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M. vanbaalenii PYR-1 Mvan_3797 (-)

annotation: putative GAF sensor protein
coordinates: 4042485 - 4044971
length: 828

DELVAARDQMERLVRVIVAIGADLDLDVTLRRIVTGARELSGARYGALGIRGADGTWASFVCDGMEEDAA
RALGGLAAGEGIRIDDLTGYSGVAGLRSQKTPMRALLGVPITVRGADFGALYLADDQPDRVFSDSQEGAV
RALATAAAAAIDNARLFERERESAKWTKASREITTALLSGDPQTGPLQLIVNLALELADAEQAILLVPGE
PDLPGDEADTLVVAATAGRYASEVIGRQVPMDGSTTGGVARRGLPLITDSFQYPIEGFTDAGERSAIVMP
LIADEAVLGVIAVARRPHQPPFDNDYLELVSDFARHAAIALALAAGREHALNQELAQADSVDAALHAAAE
ELRRLWRARRVLAVTFPTHGDSVESAPKVVAVGEDTHWADLSAPTRLTLSALRDGDLLTPNTAQPGTAGI
AMQHPEGILVVWLDLTDQRSFTLEDQTLLTVLAGRLSQGLQRVHRVDQQRETALALQHAILGPADLPHGF
AVRYQAASRPLQVGGDWYDVVDLDDGRIAMIVGDCVGHGLPAATVMGQVRSACRALLFDNPSPAAALAGM
DRFAARLPGAQCATAVCAVLDPATGELVYSSAGHPPPILMHADGSARLLEGAHTIALGLRVGWSRPEGRL
SIPAGATLMLYTDGLVERRRTLLEDGISRAAELLEGHRTSDLEDLADQIMSGLAPSVGYQDDVALLLYRH
PAPLQLNFPADANHLAPARAALRSWLTSARVEPARVMDVLVAAGEALANAIEHGHRHTPDGTVSLRATAL
VDRVRLTVADTGSWKVPQPGRDSRRGRGIALMRALMHDVEIDIGRSGTSVHLDTRID*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3797--100% (828)putative GAF sensor protein
M. vanbaalenii PYR-1Mvan_1931-e-17563.47% (501) multi-sensor signal transduction histidine kinase
M. vanbaalenii PYR-1Mvan_1413-5e-8545.69% (383) GAF sensor signal transduction histidine kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2052c-2e-5435.65% (359) histidine kinase response regulator
M. gilvum PYR-GCKMflv_4521-0.074.58% (826) putative GAF sensor protein
M. tuberculosis H37RvRv2027c-2e-5435.65% (359) histidine kinase response regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3890c-2e-5036.06% (355) histidine kinase response regulator
M. marinum MMMAR_3479-1e-10156.94% (360) two-component sensor histidine kinase
M. avium 104MAV_2108-0.074.94% (830) stage II sporulation protein E (SpoIIE)
M. smegmatis MC2 155MSMEG_3941-7e-6042.90% (338) GAF family protein
M. thermoresistible (build 8)TH_2781-3e-9740.98% (510) PUTATIVE stage II sporulation protein E (SpoIIE)
M. ulcerans Agy99MUL_3853rsbU2e-4931.96% (438) regulator of sigma subunit, anti-anti-sigma factor RsbU

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3797|M.vanbaalenii_PYR-1       ------------------------------------MDELVAARDQMERL
Mflv_4521|M.gilvum_PYR-GCK          ------------MADDRNLPAFRRHGRQEGDRTDAEFDELIAARNQMDHL
MAV_2108|M.avium_104                --------------------------------MHTRLDELMAARDQLEQL
MMAR_3479|M.marinum_M               --------------------------------MHAQLDELLAARDQMEQL
MSMEG_3941|M.smegmatis_MC2_155      ------------------------------MGQSHTDDSPEAVEVRMAAL
Mb2052c|M.bovis_AF2122/97           MTHPDRANVNPGSPPVRETLSQLRLRELLLEVQDRIEQIVEG-RDRLDGL
Rv2027c|M.tuberculosis_H37Rv        MTHPDRANVNPGSPPLRETLSQLRLRELLLEVQDRIEQIVEG-RDRLDGL
MAB_3890c|M.abscessus_ATCC_199      MVEDVGAQPNR----VTAELAHLQLRELLAEVQGRIEQIVDGTRGRMDAL
TH_2781|M.thermoresistible__bu      --------------------------------------------MSPDFG
MUL_3853|M.ulcerans_Agy99           --------------------------------MLLLDLLRQRTYSFVRSV
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       VRVIVAIGADLDLDVTLRRIVTGARELSGARYGALGIRGADGTWASFVCD
Mflv_4521|M.gilvum_PYR-GCK          VRAIVAIGSDLDFSVTLERIVTAARELSGARYAGLGIRAAGGNLVSFVES
MAV_2108|M.avium_104                VRVIAEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGGLLSFVHA
MMAR_3479|M.marinum_M               LRVIVEIGSDLDLDATLRRIVLAARELTSAPYGALAVRDPEGTLIRFIHA
MSMEG_3941|M.smegmatis_MC2_155      LQDMASLDAGLEPESTLHGILDAIMRVSGACYGAAGLCAPDGTPATFLQA
Mb2052c|M.bovis_AF2122/97           IDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYE
Rv2027c|M.tuberculosis_H37Rv        IDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYE
MAB_3890c|M.abscessus_ATCC_199      LDAVMAVSSGLELDATLREIVCAASELVSARYGALGVVGSDEKLAEFVYE
TH_2781|M.thermoresistible__bu      ARYAAALAAYLE-DSSERRLAVAHDLGRQALLGRISVLQIVEDHVRLVDE
MUL_3853|M.ulcerans_Agy99           HRRDGYMAAEMDWDKNVGTANTVRRIFENVPTMLVGLEGPEHRFVAANAA
                                          : : :. . .             .     .              

Mvan_3797|M.vanbaalenii_PYR-1       GMEEDAARALGGLAAGEGIR-----------IDDLTGYSGVAGLRSQKTP
Mflv_4521|M.gilvum_PYR-GCK          GDEFDVA-ALAGLPIDGGLR-----------IDDLRDHPEITDLQALNRP
MAV_2108|M.avium_104                GLDADTARQLGELAVGDGLR-----------IDDVSVDPRSAHLSAHDPP
MMAR_3479|M.marinum_M               GMDDDVARRIGHLPVGKGVLGVSLVETPALRLDDLTMHPAACGFPEHHPP
MSMEG_3941|M.smegmatis_MC2_155      G---ALAQAVPDSPD-RDMLGFLRNRTGPLRIDGLARSAAEVGLPELLPP
Mb2052c|M.bovis_AF2122/97           GIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPP
Rv2027c|M.tuberculosis_H37Rv        GIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPP
MAB_3890c|M.abscessus_ATCC_199      GIDEATRDLIGPLPTGHGVLGVVIDEAKPLRLRDIAAHPASVGFPANHPP
TH_2781|M.thermoresistible__bu      LSRRQPVDTDTALQFLLQAL--------------AAVDVAVRGYLEGTRR
MUL_3853|M.ulcerans_Agy99           YRRFSPTFTAVGQPAREVYPELE---------SQQIYHMLDRVYETGEPQ
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       MRALLGVPITVRGADFGALYLADDQPDRVFSDSQEGAVRALATAAAAAID
Mflv_4521|M.gilvum_PYR-GCK          IRALLAIPVTVRGADFGSLYLADDRPGRVFSDAQESAVRALATAAAAAID
MAV_2108|M.avium_104                LRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAMATAAAAAID
MMAR_3479|M.marinum_M               MRAFLAVPITIRGTVFGSLYLTHVDPGRKFSESDEFAARALAFAAGVAID
MSMEG_3941|M.smegmatis_MC2_155      MRAVLGVPLVSHGEVLGSLYVADSRAGFEFSDAHVGVVEVLATVAADVVH
Mb2052c|M.bovis_AF2122/97           MRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVD
Rv2027c|M.tuberculosis_H37Rv        MRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVD
MAB_3890c|M.abscessus_ATCC_199      MRTFLGVPVQVRGEVFGRLYLTEKLDGQEFTEDDEVVVRALAGAAGIAIE
TH_2781|M.thermoresistible__bu      YEQQRARAEGLAGRDTFRSALVNAMQEAFFVMDRTGSVIDINEAFAEITG
MUL_3853|M.ulcerans_Agy99           SGAEWRLQADFDGSGIDERYFDFLVTPRRREDGSIEGVQILFDDVTTRVR
                                                        .                .  :         

Mvan_3797|M.vanbaalenii_PYR-1       NARLFERERESAKWTKASREITTALLSGDPQ-TGPLQ-LIVNLALELADA
Mflv_4521|M.gilvum_PYR-GCK          NARLFEREREAARWTKASREITTALLSGDPQ-TGPLQ-LIVNRALELAGA
MAV_2108|M.avium_104                NARLFERERESAKWTKASREITTALLSGDPQ-TGPLQ-LIVNRALELAGA
MMAR_3479|M.marinum_M               NAQVFERERTAVKWMEASREITTALMSSTESRREPLQ-LIAQRACTLTDA
MSMEG_3941|M.smegmatis_MC2_155      SVWHLAKVRTVARWVSASREITMALLGMSGGEDAPLR-LIVGRAAELTVA
Mb2052c|M.bovis_AF2122/97           NARLFEESRTREAWIEATRDIGTQMLAGADP-AMVFR-LIAEEALTLMAG
Rv2027c|M.tuberculosis_H37Rv        NARLFEESRTREAWIEATRDIGTQMLAGADP-AMVFR-LIAEEALTLMAG
MAB_3890c|M.abscessus_ATCC_199      NARLYQHARRREQWQRATADITAELLGGVDP-GKALH-LVASSAALLAEA
TH_2781|M.thermoresistible__bu      YDGHDLPYRWPHPWVVDEPRADEDLLELLQHGRVQLERQIRHRSGHLAWV
MUL_3853|M.ulcerans_Agy99           --ARLAAEARVEELSERYRHLRDSAIVMQQALLAPSVPVVSGPDIAAQYL
                                                             :             :          

Mvan_3797|M.vanbaalenii_PYR-1       EQAILLVPGEPDLPGDEADTLVVAATAGRYASEVIGRQVPMDGSTTGGVA
Mflv_4521|M.gilvum_PYR-GCK          EQAILLVPLEPDVPAEDVDTLIVAATAGRYSSEVIGRQVPMAGSTTGGVA
MAV_2108|M.avium_104                EQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVA
MMAR_3479|M.marinum_M               EQAIVLVPVESDLATDEIDTLVVSAAVGLHAEEVVGQQVPVRGSTCGDVF
MSMEG_3941|M.smegmatis_MC2_155      SQAAILVPSEADRAPEEVRSLTVAVAAGARADEVEGQQVPVSGSTSGRVF
Mb2052c|M.bovis_AF2122/97           AATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVF
Rv2027c|M.tuberculosis_H37Rv        AATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVF
MAB_3890c|M.abscessus_ATCC_199      DFAFIALPAGDEE---DTAELVVAVCEGKGAEVLNDKLIPIDGSTSGSTF
TH_2781|M.thermoresistible__bu      AISVNVVNPNGTAFVGTMRDITAAHKAAARESALTRLATAAGVATS----
MUL_3853|M.ulcerans_Agy99           VAAQDTAAGGDWFDAVALGDRLVLIVGDVVGHGVEAAAVMSQLRTALRLQ
                                      :                              :          :     

Mvan_3797|M.vanbaalenii_PYR-1       RRGLPLITDSFQYPIEGFTDAGERSAIVMPLIADEAVLGVIAVARRPHQP
Mflv_4521|M.gilvum_PYR-GCK          RRGLPMITDSFQYPIEGFTDVGERSAIVMPLIVDDAVLGVIAVARRPNQP
MAV_2108|M.avium_104                RRGLPLITDSFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQP
MMAR_3479|M.marinum_M               RSGEPLISEAFSYPIEAFTDVAQRSAIVMPLSAHEKVAGVIAVARGADQP
MSMEG_3941|M.smegmatis_MC2_155      RTGESTMTDGFRYPITSFTDQGRRPAIVVPLRSATNNLGVIAVARDADDP
Mb2052c|M.bovis_AF2122/97           HDRTPRRFDRLDLAVDG--PVEPGPALVLPLRAADTVAGVLVALRSADEQ
Rv2027c|M.tuberculosis_H37Rv        HDRTPRRFDRLDLAVDG--PVEPGPALVLPLRAADTVAGVLVALRSADEQ
MAB_3890c|M.abscessus_ATCC_199      IDHEPRNVGRLAVNLAEGTDLAFGPALVLPLGGGESTAGVLILLRTVGAI
TH_2781|M.thermoresistible__bu      ------VSEVLSIMLDECRPAIDSRRVIAVTWAREDAEPTIQVVGDPPAS
MUL_3853|M.ulcerans_Agy99           IAAGRSIGEALEALDAFHEHVPGSNSATLCVGSLDFTTGEFQYCTAGHPP
                                              :                             :         

Mvan_3797|M.vanbaalenii_PYR-1       PFDNDYLELVSDFARHAAIALALAAGREHALNQELAQADSVDAALHAAAE
Mflv_4521|M.gilvum_PYR-GCK          AFDEDYLELVSDFARHASIALALAAGREHALNRQLAQADSVSEAMAGAAE
MAV_2108|M.avium_104                PFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVDEAVRAAAE
MMAR_3479|M.marinum_M               PFDARCLDLVSQFATHAAIALLLASGREDAR-QLTILAERERIAHDLHDH
MSMEG_3941|M.smegmatis_MC2_155      PFDVDEMAIMEDFAHHAAVALTLCRANEQAR-QLTVLSDRERIARDLHDH
Mb2052c|M.bovis_AF2122/97           PFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDRIARDLHDH
Rv2027c|M.tuberculosis_H37Rv        PFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDRIARDLHDH
MAB_3890c|M.abscessus_ATCC_199      AFDEEQLDMAASFAGQAALALEQAEVRLAKH-ELDVLADRDRIARDLHDH
TH_2781|M.thermoresistible__bu      TWADLDESLRTTLLAARDWPPLTVQPVSDAG-----QNTSRGIVAVLSGT
MUL_3853|M.ulcerans_Agy99           PLVVTAEAKARYLEPSGAGPLGSDTGFPVRT----ELIGVGDVVLLYTDG
                                    .           :      .                       .      

Mvan_3797|M.vanbaalenii_PYR-1       ELRRLWRARRVLAVTFPTHGDSVES---APKVVAVGEDTHWADLSAPTRL
Mflv_4521|M.gilvum_PYR-GCK          ELRRLWRARRVLAVTFPTRSEAADV---EPVVVSAGEHTTWRELPDGIRQ
MAV_2108|M.avium_104                ELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQ
MMAR_3479|M.marinum_M               VIQRLFASGMDLQGTLA---------------------------------
MSMEG_3941|M.smegmatis_MC2_155      VIQRLFLAGMDLQGTIA---------------------------------
Mb2052c|M.bovis_AF2122/97           VIQRLFAVGLTLQGAAP---------------------------------
Rv2027c|M.tuberculosis_H37Rv        VIQRLFAVGLTLQGAAP---------------------------------
MAB_3890c|M.abscessus_ATCC_199      VIQRLFAVGLAMQSTHR---------------------------------
TH_2781|M.thermoresistible__bu      PATVLWLEHRVPRPVGID--------------------------------
MUL_3853|M.ulcerans_Agy99           LIERPGRPLGASTAEFAD--------------------------------
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       TLSALRDGDLLTPNTAQPGTAGIAMQHPEGILVVWLDLTDQRSFTLEDQT
Mflv_4521|M.gilvum_PYR-GCK          ILLSMRRGDLLTPNAAEPGTAGIAVQHPEGILVVWIELAEHRSFTLEDQT
MAV_2108|M.avium_104                ALGSLRDGDLLTPNTTQPGTAGIALQHPDGVLVVWIDLTDERSFTLEDQT
MMAR_3479|M.marinum_M               ------------------------------------------------RA
MSMEG_3941|M.smegmatis_MC2_155      ------------------------------------------------RT
Mb2052c|M.bovis_AF2122/97           ------------------------------------------------RA
Rv2027c|M.tuberculosis_H37Rv        ------------------------------------------------RA
MAB_3890c|M.abscessus_ATCC_199      ------------------------------------------------RS
TH_2781|M.thermoresistible__bu      -----------------------------------------------GRR
MUL_3853|M.ulcerans_Agy99           -------------------------------------------------L
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       LLTVLAGRLSQGLQRVHRVDQQRETALALQHAILGPADLPHGFAVRYQAA
Mflv_4521|M.gilvum_PYR-GCK          LLTVLAGRLSAGLQRVHQVDQQRETALALQHAILGPAHLPPGFTVRYQAA
MAV_2108|M.avium_104                LLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNGFAVRYQAA
MMAR_3479|M.marinum_M               RSPEVIDRLNRTVDDLQTIIEEIRSTIFQLKSPS---GRDGGFRQRIQQV
MSMEG_3941|M.smegmatis_MC2_155      KSDLLKERLSRTVDDLQSIIDEIRTAIFDLQSPA---ASAMSFRQRIQAA
Mb2052c|M.bovis_AF2122/97           RVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGP---SRATGLRHRLDKV
Rv2027c|M.tuberculosis_H37Rv        RVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGP---SRATGLRHRLDKV
MAB_3890c|M.abscessus_ATCC_199      VDPTVAARLADHIDQLHEVIQEIRTAIFDLHTN------DESLRATLRST
TH_2781|M.thermoresistible__bu      LINALVGHVSLAVQHVRRFEIARESSLTLQRAMLPDIVPPPGFAVRYEPA
MUL_3853|M.ulcerans_Agy99           AANITSGGGFVIDAQSRPIDRLCSETLELLLRSTGYNDDITLLAVQRRAP
                                                    : .      ::               :       

Mvan_3797|M.vanbaalenii_PYR-1       SRPLQVGGDWYDVVDLDDGRIAMIVGDCVGHGLPAATVMGQVRSACRALL
Mflv_4521|M.gilvum_PYR-GCK          SRPLQVGGDWYDVVDLDDGRIALIVGDCVGHGLAAATVMGQVRSACRALL
MAV_2108|M.avium_104                TRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALL
MMAR_3479|M.marinum_M               VADLTEHRDVVTTIHMHG---PMSAVQGELADHAEAVATEAISNAVRHSG
MSMEG_3941|M.smegmatis_MC2_155      VAAVTDNSPLATTVRISG---PIVAVDPALADDAEAVIVEAISNAVRHSG
Mb2052c|M.bovis_AF2122/97           IDQLAIP-ALHTTVQYTG---PLSVVDTVLANHAEAVLREAVSNAVRHAN
Rv2027c|M.tuberculosis_H37Rv        IDQLAIP-ALHTTVQYTG---PLSVVDTVLANHAEAVLREAVSNAVRHAN
MAB_3890c|M.abscessus_ATCC_199      INELTAETGLRVSVRMSG---PLDVVPASTSGDAEAVVREAVSNVVRHAR
TH_2781|M.thermoresistible__bu      VRPLEIGGDWYDVLPLDDHQIGIIVGDCVGRGLPAAAVMGQLRSSARALL
MUL_3853|M.ulcerans_Agy99           TPPLNITEDATIHAARAIRSRLRQWLSEIGADSGDISDIVHAISEFVENA
                                       :                           .           .      

Mvan_3797|M.vanbaalenii_PYR-1       FDNPSPAAALAGMDRFAARLPGAQCATAVCAVLDPATGELVYSSAGHPPP
Mflv_4521|M.gilvum_PYR-GCK          LENPSPGAALSGMDRFAARLPGAQCTTAVVMVLDPASGEIAYSSAGHPPP
MAV_2108|M.avium_104                IENPSPAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVYSSAGHPPP
MMAR_3479|M.marinum_M               AGRVTLDVSVGDMFSLEVVDDGCGISPDVSRRSGLANMRSRAEKLGGTCG
MSMEG_3941|M.smegmatis_MC2_155      ATSVTISIEVSDRLDIEVVDNGRGIPANTARCSGLANLKARAQQAGGSCQ
Mb2052c|M.bovis_AF2122/97           ATSLAINVSVEDDVRVEVVDDGVGISGDITE-SGLRNLRQRADDAGGEFT
Rv2027c|M.tuberculosis_H37Rv        ATSLAINVSVEDDVRVEVVDDGVGISGDITE-SGLRNLRQRADDAGGEFT
MAB_3890c|M.abscessus_ATCC_199      ARELSVTVSVDDELVIEVVDDGIGIPDVVAR-SGLSGLANRAAQSGGTFS
TH_2781|M.thermoresistible__bu      LSGAEPARLLENLDAVAALIPDAYCATVLLAVLDTESGTLRYSNAGHVPA
MUL_3853|M.ulcerans_Agy99           VEHGYSTDVSDGLAVAAALGGDGKLRVAVIDHGTWKHHREGERGRGRGLA
                                               .     .   .                       *    

Mvan_3797|M.vanbaalenii_PYR-1       ILMHADGSARLLEGAHTIALGLRVGWSRPEGRLSIPAGATLMLYTDGLVE
Mflv_4521|M.gilvum_PYR-GCK          LVVHADGEVETFDDAHTIALGLRLNWVRPETRRTLEVGSTLVLYTDGLVE
MAV_2108|M.avium_104                IVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVE
MMAR_3479|M.marinum_M               ITTPTEG-------------GTRISWTVPFGDL-----------------
MSMEG_3941|M.smegmatis_MC2_155      ITSSAGS-------------GTHVRWSAPLSGA-----------------
Mb2052c|M.bovis_AF2122/97           VENMPTG-------------GTLLRWSAPLR-------------------
Rv2027c|M.tuberculosis_H37Rv        VENMPTG-------------GTLLRWSAPLR-------------------
MAB_3890c|M.abscessus_ATCC_199      VSAMDTG-------------GTRLVWSAPLP-------------------
TH_2781|M.thermoresistible__bu      LLAGPGPHATVLTDGASVPLGVQQNRPRPQVSRQLTPGSTLMLYTDGLVE
MUL_3853|M.ulcerans_Agy99           MAEALVS-----------ETHVSHDGAGTTATVVHRLSRPAQFVTDPVVS
                                    :                           .                     

Mvan_3797|M.vanbaalenii_PYR-1       RRRTLLEDGISRAAELLEGHRTSDLEDLADQIMSGLAPSVGYQDDVALLL
Mflv_4521|M.gilvum_PYR-GCK          RRRIPLEEGISRATDVVVEHRAAPLDDLANAIMSELAPSVGYQDDVALLL
MAV_2108|M.avium_104                RRRSPLDRGIYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLL
MMAR_3479|M.marinum_M               --------------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155      --------------------------------------------------
Mb2052c|M.bovis_AF2122/97           --------------------------------------------------
Rv2027c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_3890c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2781|M.thermoresistible__bu      RRDSPIDTGMDRACQVLTAMLDAEPEAVADAMLDTLAPADGYDDDVAIVV
MUL_3853|M.ulcerans_Agy99           RAPNRPAIDSEFASTVTESGHIVVRGDVDSNTAPTLDRQIAVES------
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       YRH-PAPLQLNFPADANHLAPARAALRSWLTSARVEPARVMDVLVAAGEA
Mflv_4521|M.gilvum_PYR-GCK          YRH-PAPLELTFPAHADHLAPTRTALRRWLSGAKVEQGRVMEVLVAAGEA
MAV_2108|M.avium_104                YRH-PAPLELNFPADVNQLAPARTALRNWLRRVRLDPEQTLNVLVAAGEA
MMAR_3479|M.marinum_M               --------------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155      --------------------------------------------------
Mb2052c|M.bovis_AF2122/97           --------------------------------------------------
Rv2027c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_3890c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2781|M.thermoresistible__bu      YRHTFAPLRIELPATPDRLSEVRARLTGWLTAAGAPELLISDIVLAVNEA
MUL_3853|M.ulcerans_Agy99           -RSGIASLTIDLSAVTHLGSAG------------------VSALVTARDR
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       LANAIEHGHRHTPDGTVSLRATALVDRVRLTVADTGSWKVPQPGRDSRRG
Mflv_4521|M.gilvum_PYR-GCK          VANAIEHGHRHGPPGTVRLRATALVDLVELIITDSGSWKPPSAIPDTYRG
MAV_2108|M.avium_104                VANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRG
MMAR_3479|M.marinum_M               --------------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155      --------------------------------------------------
Mb2052c|M.bovis_AF2122/97           --------------------------------------------------
Rv2027c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_3890c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2781|M.thermoresistible__bu      CTNSVEHAYRDREPGPMQVYADLRDGQIMLQVRDFGTWKTPEPNP-RIRG
MUL_3853|M.ulcerans_Agy99           ARKQGGRCVLMAPPGSPAHHVLSLVQIPVISGETENVFAED---------
                                                                                      

Mvan_3797|M.vanbaalenii_PYR-1       RGIALMRALMHDVEIDIGRSGTSVHLDTRID------
Mflv_4521|M.gilvum_PYR-GCK          RGIGIMRGLMQDVTIAHDSDGTTIHLYARIS------
MAV_2108|M.avium_104                RGIPLMKSLMNDVDIRSDTGGTTVQLSARIT------
MMAR_3479|M.marinum_M               -------------------------------------
MSMEG_3941|M.smegmatis_MC2_155      -------------------------------------
Mb2052c|M.bovis_AF2122/97           -------------------------------------
Rv2027c|M.tuberculosis_H37Rv        -------------------------------------
MAB_3890c|M.abscessus_ATCC_199      -------------------------------------
TH_2781|M.thermoresistible__bu      RGLPMMRAISADVQVDNTRSGTVVELTFTLSGQPALT
MUL_3853|M.ulcerans_Agy99           -------------------------------------