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MHTRLDELMAARDQLEQLVRVIAEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGGLLSFVHAGL DADTARQLGELAVGDGLRIDDVSVDPRSAHLSAHDPPLRALLGIPITVRAANFGNLYLADDRQGRVFTDS QEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLSGDPQTGPLQLIVNRALELAGAEQAIL LVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVARRGLPLITDSFQYPIEGFTDVGERS AIVIPLIADGAVLGVIAVARDPQQPPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVDEAV RAAAEELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGSLRDGDLLTPNT TQPGTAGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILG PADLPNGFAVRYQAATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALLIENPS PAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVYSSAGHPPPIVVHGDGSTQILDEGHTIALGIRRD WPRPEARVTIPARATLLLYTDGLVERRRSPLDRGIYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDD VVLLLYRHPAPLELNFPADVNQLAPARTALRNWLRRVRLDPEQTLNVLVAAGEAVANAIEHGHRHSPQGT IRLGATALGDQVRLTITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTGGTTVQLSARIT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2108 | - | - | 100% (835) | stage II sporulation protein E (SpoIIE) |
| M. avium 104 | MAV_4108 | - | 2e-99 | 56.81% (345) | GAF family protein |
| M. avium 104 | MAV_0430 | - | 1e-93 | 37.34% (533) | stage II sporulation protein E (SpoIIE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2052c | - | 1e-56 | 35.63% (348) | histidine kinase response regulator |
| M. gilvum PYR-GCK | Mflv_4521 | - | 0.0 | 70.72% (830) | putative GAF sensor protein |
| M. tuberculosis H37Rv | Rv2027c | - | 1e-56 | 35.63% (348) | histidine kinase response regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3890c | - | 3e-46 | 33.98% (359) | histidine kinase response regulator |
| M. marinum M | MMAR_3479 | - | 1e-100 | 56.48% (347) | two-component sensor histidine kinase |
| M. smegmatis MC2 155 | MSMEG_3941 | - | 3e-57 | 40.24% (338) | GAF family protein |
| M. thermoresistible (build 8) | TH_2781 | - | 2e-87 | 35.98% (517) | PUTATIVE stage II sporulation protein E (SpoIIE) |
| M. ulcerans Agy99 | MUL_2422 | devS | 4e-51 | 32.69% (364) | two component sensor histidine kinase DevS |
| M. vanbaalenii PYR-1 | Mvan_3797 | - | 0.0 | 74.94% (830) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4521|M.gilvum_PYR-GCK ---------------------MADDRNLPAFRRHGRQEGDRTDAEFDELI
Mvan_3797|M.vanbaalenii_PYR-1 ---------------------------------------------MDELV
MAV_2108|M.avium_104 -----------------------------------------MHTRLDELM
MMAR_3479|M.marinum_M -----------------------------------------MHAQLDELL
MSMEG_3941|M.smegmatis_MC2_155 ---------------------------------------MGQSHTDDSPE
Mb2052c|M.bovis_AF2122/97 MT---HPDRANVNPGSP------PVRETLSQLRLRELLLEVQDRIEQIVE
Rv2027c|M.tuberculosis_H37Rv MT---HPDRANVNPGSP------PLRETLSQLRLRELLLEVQDRIEQIVE
MUL_2422|M.ulcerans_Agy99 MTDEPHPQDAGPSLGVPSGDGLRPLRLTLSQLRLRELLVEVQERVEQIVE
MAB_3890c|M.abscessus_ATCC_199 -----MVEDVGAQPNRV--------TAELAHLQLRELLAEVQGRIEQIVD
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mflv_4521|M.gilvum_PYR-GCK AARNQMDHLVRAIVAIGSDLDFSVTLERIVTAARELSGARYAGLGIRAAG
Mvan_3797|M.vanbaalenii_PYR-1 AARDQMERLVRVIVAIGADLDLDVTLRRIVTGARELSGARYGALGIRGAD
MAV_2108|M.avium_104 AARDQLEQLVRVIAEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASD
MMAR_3479|M.marinum_M AARDQMEQLLRVIVEIGSDLDLDATLRRIVLAARELTSAPYGALAVRDPE
MSMEG_3941|M.smegmatis_MC2_155 AVEVRMAALLQDMASLDAGLEPESTLHGILDAIMRVSGACYGAAGLCAPD
Mb2052c|M.bovis_AF2122/97 G-RDRLDGLIDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYD
Rv2027c|M.tuberculosis_H37Rv G-RDRLDGLIDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYD
MUL_2422|M.ulcerans_Agy99 G-RDRLDGLVEAMLVVTSGLELDATLRTIVHSATNLVDARYCALEVHDRD
MAB_3890c|M.abscessus_ATCC_199 GTRGRMDALLDAVMAVSSGLELDATLREIVCAASELVSARYGALGVVGSD
TH_2781|M.thermoresistible__bu -MSPDFGARYAAALAAYLEDSSERRLAVAHDLGRQALLGRISVLQIVEDH
: . . * . .
Mflv_4521|M.gilvum_PYR-GCK GNLVSFVESGDEFDVA-ALAGLPIDGGLR-----------IDDLRDHPEI
Mvan_3797|M.vanbaalenii_PYR-1 GTWASFVCDGMEEDAARALGGLAAGEGIR-----------IDDLTGYSGV
MAV_2108|M.avium_104 GGLLSFVHAGLDADTARQLGELAVGDGLR-----------IDDVSVDPRS
MMAR_3479|M.marinum_M GTLIRFIHAGMDDDVARRIGHLPVGKGVLGVSLVETPALRLDDLTMHPAA
MSMEG_3941|M.smegmatis_MC2_155 GTPATFLQAG---ALAQAVPDSPD-RDMLGFLRNRTGPLRIDGLARSAAE
Mb2052c|M.bovis_AF2122/97 HRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPAS
Rv2027c|M.tuberculosis_H37Rv HRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPAS
MUL_2422|M.ulcerans_Agy99 KRVLQFVYEGIDEDTVARIGHLPEGLGIIGLLIDEPKPLRLEDISQHPAS
MAB_3890c|M.abscessus_ATCC_199 EKLAEFVYEGIDEATRDLIGPLPTGHGVLGVVIDEAKPLRLRDIAAHPAS
TH_2781|M.thermoresistible__bu VRLVDELSRRQPVDTDTALQFLLQALAAV-----------------DVAV
: :
Mflv_4521|M.gilvum_PYR-GCK TDLQALNRPIRALLAIPVTVRGADFGSLYLADDRPGRVFSDAQESAVRAL
Mvan_3797|M.vanbaalenii_PYR-1 AGLRSQKTPMRALLGVPITVRGADFGALYLADDQPDRVFSDSQEGAVRAL
MAV_2108|M.avium_104 AHLSAHDPPLRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAM
MMAR_3479|M.marinum_M CGFPEHHPPMRAFLAVPITIRGTVFGSLYLTHVDPGRKFSESDEFAARAL
MSMEG_3941|M.smegmatis_MC2_155 VGLPELLPPMRAVLGVPLVSHGEVLGSLYVADSRAGFEFSDAHVGVVEVL
Mb2052c|M.bovis_AF2122/97 VGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQAL
Rv2027c|M.tuberculosis_H37Rv VGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQAL
MUL_2422|M.ulcerans_Agy99 IGFPSHHPPMRTFLGVPVRVRDVSLGTLYLTDKTNGQPFSDDDELLVQAL
MAB_3890c|M.abscessus_ATCC_199 VGFPANHPPMRTFLGVPVQVRGEVFGRLYLTEKLDGQEFTEDDEVVVRAL
TH_2781|M.thermoresistible__bu RGYLEGTRRYEQQRARAEGLAGRDTFRSALVNAMQEAFFVMDRTGSVIDI
. . . :.. * . :
Mflv_4521|M.gilvum_PYR-GCK ATAAAAAIDNARLFEREREAARWTKASREITTALLSG-DPQTGPLQLIVN
Mvan_3797|M.vanbaalenii_PYR-1 ATAAAAAIDNARLFERERESAKWTKASREITTALLSG-DPQTGPLQLIVN
MAV_2108|M.avium_104 ATAAAAAIDNARLFERERESAKWTKASREITTALLSG-DPQTGPLQLIVN
MMAR_3479|M.marinum_M AFAAGVAIDNAQVFERERTAVKWMEASREITTALMSSTESRREPLQLIAQ
MSMEG_3941|M.smegmatis_MC2_155 ATVAADVVHSVWHLAKVRTVARWVSASREITMALLGMSGGEDAPLRLIVG
Mb2052c|M.bovis_AF2122/97 AAAAGIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPA-MVFRLIAE
Rv2027c|M.tuberculosis_H37Rv AAAAGIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPA-MVFRLIAE
MUL_2422|M.ulcerans_Agy99 AAAAGIAIANARLYEQAKARQAWIGATRDIATELLSGTEPA-SVFRLVAE
MAB_3890c|M.abscessus_ATCC_199 AGAAGIAIENARLYQHARRREQWQRATADITAELLGGVDPG-KALHLVAS
TH_2781|M.thermoresistible__bu NEAFAEITGYDGHDLPYRWPHPWVVDEPRADEDLLELLQHG----RVQLE
. . : * :: ::
Mflv_4521|M.gilvum_PYR-GCK RALELAGAEQAILLVPLEPDVPAEDVDTLIVAATAGRYSSEVIGRQVPMA
Mvan_3797|M.vanbaalenii_PYR-1 LALELADAEQAILLVPGEPDLPGDEADTLVVAATAGRYASEVIGRQVPMD
MAV_2108|M.avium_104 RALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMD
MMAR_3479|M.marinum_M RACTLTDAEQAIVLVPVESDLATDEIDTLVVSAAVGLHAEEVVGQQVPVR
MSMEG_3941|M.smegmatis_MC2_155 RAAELTVASQAAILVPSEADRAPEEVRSLTVAVAAGARADEVEGQQVPVS
Mb2052c|M.bovis_AF2122/97 EALTLMAGAATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVS
Rv2027c|M.tuberculosis_H37Rv EALTLMAGAATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVS
MUL_2422|M.ulcerans_Agy99 EALKLTSADAALVAIPVDEDVPASEVAQLLVIETVGNAVAAAEGCTIAVA
MAB_3890c|M.abscessus_ATCC_199 SAALLAEADFAFIALPAGDEE---DTAELVVAVCEGKGAEVLNDKLIPID
TH_2781|M.thermoresistible__bu RQIRHRSGHLAWVAISVNVVNPNGTAFVGTMRDITAAHKAAARESALTRL
. : : :. : . :.
Mflv_4521|M.gilvum_PYR-GCK GSTTGGVARRGLPMITDSFQYPIEGFTDVGERSAIVMPLIVDDAVLGVIA
Mvan_3797|M.vanbaalenii_PYR-1 GSTTGGVARRGLPLITDSFQYPIEGFTDAGERSAIVMPLIADEAVLGVIA
MAV_2108|M.avium_104 GSTTGGVARRGLPLITDSFQYPIEGFTDVGERSAIVIPLIADGAVLGVIA
MMAR_3479|M.marinum_M GSTCGDVFRSGEPLISEAFSYPIEAFTDVAQRSAIVMPLSAHEKVAGVIA
MSMEG_3941|M.smegmatis_MC2_155 GSTSGRVFRTGESTMTDGFRYPITSFTDQGRRPAIVVPLRSATNNLGVIA
Mb2052c|M.bovis_AF2122/97 GTSIGGVFHDRTPRRFDRLDLA-VDGPVEP-GPALVLPLRAADTVAGVLV
Rv2027c|M.tuberculosis_H37Rv GTSIGGVFHDRTPRRFDRLDLA-VDGPVEP-GPALVLPLRAADTVAGVLV
MUL_2422|M.ulcerans_Agy99 GTALAEVLLDSAPRQVDKIAVEDVDELGDM-GPALVLPLRATDAVAGVVV
MAB_3890c|M.abscessus_ATCC_199 GSTSGSTFIDHEPRNVGRLAVNLAEGTDLAFGPALVLPLGGGESTAGVLI
TH_2781|M.thermoresistible__bu ATAAG-----VATSVSEVLSIMLDECRPAIDSRRVIAVTWAREDAEPTIQ
.:: . . : :: .:
Mflv_4521|M.gilvum_PYR-GCK VARRPNQPAFDEDYLELVSDFARHASIALALAAGREHALNRQLAQADSVS
Mvan_3797|M.vanbaalenii_PYR-1 VARRPHQPPFDNDYLELVSDFARHAAIALALAAGREHALNQELAQADSVD
MAV_2108|M.avium_104 VARDPQQPPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVD
MMAR_3479|M.marinum_M VARGADQPPFDARCLDLVSQFATHAAIALLLASGREDAR-QLTILAERER
MSMEG_3941|M.smegmatis_MC2_155 VARDADDPPFDVDEMAIMEDFAHHAAVALTLCRANEQAR-QLTVLSDRER
Mb2052c|M.bovis_AF2122/97 ALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDR
Rv2027c|M.tuberculosis_H37Rv ALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQRQMR-EVEILTDRDR
MUL_2422|M.ulcerans_Agy99 LLHPSSPESVTEEQLEMMAAFADQAALALQLATSQRRMR-ELDVVTERDR
MAB_3890c|M.abscessus_ATCC_199 LLRTVGAIAFDEEQLDMAASFAGQAALALEQAEVRLAKH-ELDVLADRDR
TH_2781|M.thermoresistible__bu VVGDPPASTWADLDESLRTTLLAARDWPPLTVQPVSDAG-----QNTSRG
. : : .
Mflv_4521|M.gilvum_PYR-GCK EAMAGAAEELRRLWRARRVLAVTFPTRSEAADV---EPVVVSAGEHTTWR
Mvan_3797|M.vanbaalenii_PYR-1 AALHAAAEELRRLWRARRVLAVTFPTHGDSVES---APKVVAVGEDTHWA
MAV_2108|M.avium_104 EAVRAAAEELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWA
MMAR_3479|M.marinum_M IAHDLHDHVIQRLFASGMDLQGTLA-------------------------
MSMEG_3941|M.smegmatis_MC2_155 IARDLHDHVIQRLFLAGMDLQGTIA-------------------------
Mb2052c|M.bovis_AF2122/97 IARDLHDHVIQRLFAVGLTLQGAAP-------------------------
Rv2027c|M.tuberculosis_H37Rv IARDLHDHVIQRLFAVGLTLQGAAP-------------------------
MUL_2422|M.ulcerans_Agy99 IARDLHDHVIQRLFAIGLALQGSVP-------------------------
MAB_3890c|M.abscessus_ATCC_199 IARDLHDHVIQRLFAVGLAMQSTHR-------------------------
TH_2781|M.thermoresistible__bu IVAVLSGTPATVLWLEHRVPRPVGID------------------------
. *:
Mflv_4521|M.gilvum_PYR-GCK ELPDGIRQILLSMRRGDLLTPNAAEPGTAGIAVQHPEGILVVWIELAEHR
Mvan_3797|M.vanbaalenii_PYR-1 DLSAPTRLTLSALRDGDLLTPNTAQPGTAGIAMQHPEGILVVWLDLTDQR
MAV_2108|M.avium_104 DLPSHMHQALGSLRDGDLLTPNTTQPGTAGIALQHPDGVLVVWIDLTDER
MMAR_3479|M.marinum_M --------------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155 --------------------------------------------------
Mb2052c|M.bovis_AF2122/97 --------------------------------------------------
Rv2027c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2422|M.ulcerans_Agy99 --------------------------------------------------
MAB_3890c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mflv_4521|M.gilvum_PYR-GCK SFTLEDQTLLTVLAGRLSAGLQRVHQVDQQRETALALQHAILGPAHLPPG
Mvan_3797|M.vanbaalenii_PYR-1 SFTLEDQTLLTVLAGRLSQGLQRVHRVDQQRETALALQHAILGPADLPHG
MAV_2108|M.avium_104 SFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNG
MMAR_3479|M.marinum_M ------RARSPEVIDRLNRTVDDLQTIIEEIRSTIFQLK---SPSGRDGG
MSMEG_3941|M.smegmatis_MC2_155 ------RTKSDLLKERLSRTVDDLQSIIDEIRTAIFDLQ---SPAASAMS
Mb2052c|M.bovis_AF2122/97 ------RARVPAVRESIYSSIDDLQEIIQEIRSAIFDLH---AGPSRATG
Rv2027c|M.tuberculosis_H37Rv ------RARVPAVRESIYSSIDDLQEIIQEIRSAIFDLH---AGPSRATG
MUL_2422|M.ulcerans_Agy99 ------RTREPKVQQRLSEVIDDLQGVIQEIRTTIFDLH---GSSQGVTR
MAB_3890c|M.abscessus_ATCC_199 ------RSVDPTVAARLADHIDQLHEVIQEIRTAIFDLH---TNDE---S
TH_2781|M.thermoresistible__bu -----GRRLINALVGHVSLAVQHVRRFEIARESSLTLQRAMLPDIVPPPG
: : : :: :: . .::: :
Mflv_4521|M.gilvum_PYR-GCK FTVRYQAASRPLQVGGDWYDVVDLDDGRIALIVGDCVGHGLAAATVMGQV
Mvan_3797|M.vanbaalenii_PYR-1 FAVRYQAASRPLQVGGDWYDVVDLDDGRIAMIVGDCVGHGLPAATVMGQV
MAV_2108|M.avium_104 FAVRYQAATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQV
MMAR_3479|M.marinum_M FRQRIQQVVADLTEHRDVVTTIHMHG---------------PMSAVQGEL
MSMEG_3941|M.smegmatis_MC2_155 FRQRIQAAVAAVTDNSPLATTVRISG---------------PIVAVDPAL
Mb2052c|M.bovis_AF2122/97 LRHRLDKVIDQLAIP-ALHTTVQYTG---------------PLSVVDTVL
Rv2027c|M.tuberculosis_H37Rv LRHRLDKVIDQLAIP-ALHTTVQYTG---------------PLSVVDTVL
MUL_2422|M.ulcerans_Agy99 LRQRIDAAVAAFGSS-GLRTTVQFIG---------------PLSVVDNVL
MAB_3890c|M.abscessus_ATCC_199 LRATLRSTINELTAETGLRVSVRMSG---------------PLDVVPAST
TH_2781|M.thermoresistible__bu FAVRYEPAVRPLEIGGDWYDVLPLDDHQIGIIVGDCVGRGLPAAAVMGQL
: . . : . . .*
Mflv_4521|M.gilvum_PYR-GCK RSACRALLLENPSPGAALSGMDRFAARLPGAQCTTAVVMVLDPASGEIAY
Mvan_3797|M.vanbaalenii_PYR-1 RSACRALLFDNPSPAAALAGMDRFAARLPGAQCATAVCAVLDPATGELVY
MAV_2108|M.avium_104 RSACRALLIENPSPAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVY
MMAR_3479|M.marinum_M ADHAEAVATEAISN----------AVRHSGAGRVTLDVSVGDMFSLEVVD
MSMEG_3941|M.smegmatis_MC2_155 ADDAEAVIVEAISN----------AVRHSGATSVTISIEVSDRLDIEVVD
Mb2052c|M.bovis_AF2122/97 ANHAEAVLREAVSN----------AVRHANATSLAINVSVEDDVRVEVVD
Rv2027c|M.tuberculosis_H37Rv ANHAEAVLREAVSN----------AVRHANATSLAINVSVEDDVRVEVVD
MUL_2422|M.ulcerans_Agy99 ADHAEAVVREAVSN----------AVRHAQATTLTVRVKVDDDLCIEVSD
MAB_3890c|M.abscessus_ATCC_199 SGDAEAVVREAVSN----------VVRHARARELSVTVSVDDELVIEVVD
TH_2781|M.thermoresistible__bu RSSARALLLSGAEPARLLENLDAVAALIPDAYCATVLLAVLDTESGTLRY
. ..*: . . .. . * : * :
Mflv_4521|M.gilvum_PYR-GCK SSAGHPPPLVVHADGEVETFDDAHTIALGLRLNWVRPETRRTLEVGSTLV
Mvan_3797|M.vanbaalenii_PYR-1 SSAGHPPPILMHADGSARLLEGAHTIALGLRVGWSRPEGRLSIPAGATLM
MAV_2108|M.avium_104 SSAGHPPPIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLL
MMAR_3479|M.marinum_M DGCGISPDVSRR--------------------------------------
MSMEG_3941|M.smegmatis_MC2_155 NGRGIPANTARC--------------------------------------
Mb2052c|M.bovis_AF2122/97 DGVGISGDITE---------------------------------------
Rv2027c|M.tuberculosis_H37Rv DGVGISGDITE---------------------------------------
MUL_2422|M.ulcerans_Agy99 NGRGMPKTYTS---------------------------------------
MAB_3890c|M.abscessus_ATCC_199 DGIGIPDVVAR---------------------------------------
TH_2781|M.thermoresistible__bu SNAGHVPALLAGPGPHATVLTDGASVPLGVQQNRPRPQVSRQLTPGSTLM
.. *
Mflv_4521|M.gilvum_PYR-GCK LYTDGLVERRRIPLEEGISRATDVVVEHRAAPLDDLANAIMSELAPSVGY
Mvan_3797|M.vanbaalenii_PYR-1 LYTDGLVERRRTLLEDGISRAAELLEGHRTSDLEDLADQIMSGLAPSVGY
MAV_2108|M.avium_104 LYTDGLVERRRSPLDRGIYRVATVAQDARGSSLDELATRIMSAVAPSGGY
MMAR_3479|M.marinum_M ---SGLANMRSRAEKLGGTCGITTPTEGG---------------------
MSMEG_3941|M.smegmatis_MC2_155 ---SGLANLKARAQQAGGSCQITSSAGSG---------------------
Mb2052c|M.bovis_AF2122/97 ---SGLRNLRQRADDAGGEFTVENMPTGG---------------------
Rv2027c|M.tuberculosis_H37Rv ---SGLRNLRQRADDAGGEFTVENMPTGG---------------------
MUL_2422|M.ulcerans_Agy99 ---SGLTNLRRRAQEAGGQFTIESPAAGGG--------------------
MAB_3890c|M.abscessus_ATCC_199 ---SGLSGLANRAAQSGGTFSVSAMDTGG---------------------
TH_2781|M.thermoresistible__bu LYTDGLVERRDSPIDTGMDRACQVLTAMLDAEPEAVADAMLDTLAPADGY
.** . *
Mflv_4521|M.gilvum_PYR-GCK QDDVALLLYRHP-APLELTFPAHADHLAPTRTALRRWLSGAKVEQGRVME
Mvan_3797|M.vanbaalenii_PYR-1 QDDVALLLYRHP-APLQLNFPADANHLAPARAALRSWLTSARVEPARVMD
MAV_2108|M.avium_104 QDDVVLLLYRHP-APLELNFPADVNQLAPARTALRNWLRRVRLDPEQTLN
MMAR_3479|M.marinum_M ------TRISWT-VPFGDL-------------------------------
MSMEG_3941|M.smegmatis_MC2_155 ------THVRWS-APLSGA-------------------------------
Mb2052c|M.bovis_AF2122/97 ------TLLRWS-APLR---------------------------------
Rv2027c|M.tuberculosis_H37Rv ------TLLRWS-APLR---------------------------------
MUL_2422|M.ulcerans_Agy99 ------TLLRWS-APLIQ--------------------------------
MAB_3890c|M.abscessus_ATCC_199 ------TRLVWS-APLP---------------------------------
TH_2781|M.thermoresistible__bu DDDVAIVVYRHTFAPLRIELPATPDRLSEVRARLTGWLTAAGAPELLISD
. .*:
Mflv_4521|M.gilvum_PYR-GCK VLVAAGEAVANAIEHGHRHGPPGTVRLRATALVDLVELIITDSGSWKPPS
Mvan_3797|M.vanbaalenii_PYR-1 VLVAAGEALANAIEHGHRHTPDGTVSLRATALVDRVRLTVADTGSWKVPQ
MAV_2108|M.avium_104 VLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQ
MMAR_3479|M.marinum_M --------------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155 --------------------------------------------------
Mb2052c|M.bovis_AF2122/97 --------------------------------------------------
Rv2027c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2422|M.ulcerans_Agy99 --------------------------------------------------
MAB_3890c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2781|M.thermoresistible__bu IVLAVNEACTNSVEHAYRDREPGPMQVYADLRDGQIMLQVRDFGTWKTPE
Mflv_4521|M.gilvum_PYR-GCK AIPDTYRGRGIGIMRGLMQDVTIAHDSDGTTIHLYARIS------
Mvan_3797|M.vanbaalenii_PYR-1 PGRDSRRGRGIALMRALMHDVEIDIGRSGTSVHLDTRID------
MAV_2108|M.avium_104 ATSYPHRGRGIPLMKSLMNDVDIRSDTGGTTVQLSARIT------
MMAR_3479|M.marinum_M ---------------------------------------------
MSMEG_3941|M.smegmatis_MC2_155 ---------------------------------------------
Mb2052c|M.bovis_AF2122/97 ---------------------------------------------
Rv2027c|M.tuberculosis_H37Rv ---------------------------------------------
MUL_2422|M.ulcerans_Agy99 ---------------------------------------------
MAB_3890c|M.abscessus_ATCC_199 ---------------------------------------------
TH_2781|M.thermoresistible__bu PNP-RIRGRGLPMMRAISADVQVDNTRSGTVVELTFTLSGQPALT