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M. leprae Br4923 MLBr_02603 (-)

annotation: hypothetical protein MLBr_02603
coordinates: 3107415 - 3108254
length: 279

MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHGFGEHARRYDHVAHYFAAAGLATYALDLRGHGR
SAGKRVLVRDLSEYNADFDILVGIATRDHPGLKRIVAGHSMGGAIVFAYGVERPDNYDLMVLSGPAVAAQ
DMVSPLRAVVGKGLGLVAPGLPVHQLEVDAISRNRAVVAAYKDDPLVYHGKVPAGVGRVMLQVGETMTRR
APVLTTPLLVVHGSEDRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERDQVLEDVVCWILKRL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02603--100% (279)hypothetical protein MLBr_02603

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0189-1e-12374.91% (279) lysophospholipase
M. gilvum PYR-GCKMflv_0518-1e-10263.18% (277) acylglycerol lipase
M. tuberculosis H37RvRv0183-1e-12374.91% (279) lysophospholipase
M. abscessus ATCC 19977MAB_4551c-4e-8959.34% (273) lysophospholipase
M. marinum MMMAR_0427-1e-12074.55% (279) lysophospholipase
M. avium 104MAV_4997-1e-12477.26% (277) lysophospholipase
M. smegmatis MC2 155MSMEG_0220-1e-9964.13% (276) monoglyceride lipase
M. thermoresistible (build 8)TH_3727-2e-0926.92% (260) PUTATIVE Chloride peroxidase
M. ulcerans Agy99MUL_1077-1e-11973.84% (279) lysophospholipase
M. vanbaalenii PYR-1Mvan_0150-1e-10564.52% (279) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mb0189|M.bovis_AF2122/97            -MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDHV
Rv0183|M.tuberculosis_H37Rv         -MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDHV
MMAR_0427|M.marinum_M               -MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDHV
MUL_1077|M.ulcerans_Agy99           -MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDHV
MAV_4997|M.avium_104                -MN--RTERSFDGVGGVRIVYDVWTPEVAPRAVLVLAHGFGEHARRYDHV
MLBr_02603|M.leprae_Br4923          -MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHGFGEHARRYDHV
Mflv_0518|M.gilvum_PYR-GCK          ---MTHSERSFDGLGGVRIVYDVWTPESDSRGVVVLAHGYAEHARRYDHV
Mvan_0150|M.vanbaalenii_PYR-1       -MAVTRTERSFDGVGGVRIVYDVWTPETPPRGIVVLAHGYAEHARRYDHV
MSMEG_0220|M.smegmatis_MC2_155      MVSSTRSEHSFAGVGGVRIVYDVWTPDTDPRGVVVLAHGYAEHAGRYHHV
MAB_4551c|M.abscessus_ATCC_199      ------MQRTFDGADDVRIVYDTWTPAGTPRAVVVLSHGFGEHARRYDHV
TH_3727|M.thermoresistible__bu      -------MATITTSDGVEIFYRDWGSGQP----IVFSHGWPLTADDWDPQ
                                             .:   ..*.*.*  * .       ::::**    *  :.  

Mb0189|M.bovis_AF2122/97            AQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATREY
Rv0183|M.tuberculosis_H37Rv         AQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATREY
MMAR_0427|M.marinum_M               AQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATRDN
MUL_1077|M.ulcerans_Agy99           AQRLGAAGLVTYTLDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATRDN
MAV_4997|M.avium_104                ARRFGAAGLVTYALDHRGHGRSGGKRVLVRDIHEYTTDFDTLVGIATREH
MLBr_02603|M.leprae_Br4923          AHYFAAAGLATYALDLRGHGRSAGKRVLVRDLSEYNADFDILVGIATRDH
Mflv_0518|M.gilvum_PYR-GCK          AARFAESGLITYALDHRGHGRSGGKRVYLRDITEYTGDFHTLVGIARNAY
Mvan_0150|M.vanbaalenii_PYR-1       AARFAEAGLGIYALDHRGHGRSGGKRVYVRDISEYTGDFHSLVRIAAGEH
MSMEG_0220|M.smegmatis_MC2_155      AQRFGAAGLLVYALDHRGHGRSGGKRVHLRDLSEFVEDFRTLVGIAANDH
MAB_4551c|M.abscessus_ATCC_199      ARRFNEAGYLVYALDHRGHGRSGGKRVYLRDISEYTDDFGTLVDIAAREH
TH_3727|M.thermoresistible__bu      MLFFLNAGYRVIAHDRRGHGRSS-PVPDGHDMDHYADDLAALVEHLGLR-
                                       :  :*    : * ******.      :*: .:  *:  **       

Mb0189|M.bovis_AF2122/97            PGCKRIVLGHSMGGGIVFAYGVERPDN---YDLMVLSAPAVAAQDLVSP-
Rv0183|M.tuberculosis_H37Rv         PGCKRIVLGHSMGGGIVFAYGVERPDN---YDLMVLSAPAVAAQDLVSP-
MMAR_0427|M.marinum_M               PGLKCIVLGHSMGGGIVFAYGVERPDN---YDLMVLSAPAVAAQDLVSP-
MUL_1077|M.ulcerans_Agy99           PGLKCIVLGHSMGGGIVFAYGVERPDN---YDLMVLSAPAVAAQDLVSP-
MAV_4997|M.avium_104                HGLKCIVVGHSMGGGIVFAYGVERPDN---YDLMVLSGPAVAAQDQVSP-
MLBr_02603|M.leprae_Br4923          PGLKRIVAGHSMGGAIVFAYGVERPDN---YDLMVLSGPAVAAQDMVSP-
Mflv_0518|M.gilvum_PYR-GCK          PHLKLIVLGHSMGGGVVFTYGVEHPDD---YDAMVLSGPAVNAHDSVPA-
Mvan_0150|M.vanbaalenii_PYR-1       PGRKLVVLGHSMGGGVVFTYGVEHPDD---YDAMVLSGPAVDAHSSVSP-
MSMEG_0220|M.smegmatis_MC2_155      PTLPRIVLGHSMGGGIVFAYGARYPGE---YSAMVLSGPAVNAHDGVSP-
MAB_4551c|M.abscessus_ATCC_199      PDLKRIVLGHSMGGGIVFAYGVDHQDR---YDLMVLSGPAIAAQVGLPY-
TH_3727|M.thermoresistible__bu      ---DAVHVGHSTGGGVVVRYLARHGEERTAKAVLIAAVPPLMVRTDANPG
                                         :  *** **.:*. * .           :: : *.: .:      

Mb0189|M.bovis_AF2122/97            ------------VVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
Rv0183|M.tuberculosis_H37Rv         ------------VVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
MMAR_0427|M.marinum_M               ------------VIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
MUL_1077|M.ulcerans_Agy99           ------------VIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
MAV_4997|M.avium_104                ------------LLALAAKVLGVIVPGLPAQELDADAVSRDPEVVAAYRN
MLBr_02603|M.leprae_Br4923          ------------LRAVVGKGLGLVAPGLPVHQLEVDAISRNRAVVAAYKD
Mflv_0518|M.gilvum_PYR-GCK          ------------VKLVMAKVLGRIAPGLPVENLPADAVSRDPQVVSDYEN
Mvan_0150|M.vanbaalenii_PYR-1       ------------VMVLLAKVLGRLSPGLPVENLPADAVSRDPQVVAAYEN
MSMEG_0220|M.smegmatis_MC2_155      ------------VLVAVAKVLGKLAPGIPVENLDADAVSRDPEVVAAYKA
MAB_4551c|M.abscessus_ATCC_199      ------------VLTLVAPVVGRLAPGLPVQKLDVNAISHDPAIIAAYHA
TH_3727|M.thermoresistible__bu      GLPKSVFDDFQAQLAANRSEFYRALASGPFYGFNRDGVEPSEALIANWWR
                                                        .    .. *   :   .:. .  ::  :  

Mb0189|M.bovis_AF2122/97            DPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRLIPIEG
Rv0183|M.tuberculosis_H37Rv         DPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRLIPIEG
MMAR_0427|M.marinum_M               DPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHGTDDRLIPIEG
MUL_1077|M.ulcerans_Agy99           DPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHGTDDRLIPIEG
MAV_4997|M.avium_104                DPLVYHGKVPAGVGRALLQVGETMPQRAPALTAPLLVVHGSDDRLIPVAG
MLBr_02603|M.leprae_Br4923          DPLVYHGKVPAGVGRVMLQVGETMTRRAPVLTTPLLVVHGSEDRLVLVDG
Mflv_0518|M.gilvum_PYR-GCK          DPLVHHGKLPAGVGRALIAVGETMPARAAAITAPLLVVHGDKDRLIPVAG
Mvan_0150|M.vanbaalenii_PYR-1       DPLVHHGKLPAGVGRALIGVGETMPARAAAITAPLLIVHGDNDKLIPVEG
MSMEG_0220|M.smegmatis_MC2_155      DPMVHHGKLPAGIARALIGLGQSMPQRAAALTAPLLVVHGDKDRLIPVAG
MAB_4551c|M.abscessus_ATCC_199      DPLVHHGRVPAGIGRALLGVGKTMRQRAAGLKRPVLTMHGSDDRLTAPEG
TH_3727|M.thermoresistible__bu      QG--MMGDAKAHYDGIVAFSQTDFTEDLTKITVPVLVMHGDDDQVVPYAN
                                    :     *   *     :      :    . :. *:* :** .*::    .

Mb0189|M.bovis_AF2122/97            SRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTERL
Rv0183|M.tuberculosis_H37Rv         SRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTERL
MMAR_0427|M.marinum_M               SRRLVGHVGSADVELKEYPGLYHEAFNEPERDQVLDDVVSWITARL
MUL_1077|M.ulcerans_Agy99           SRRLVGHVGSADVELKEYPGPYHEAFNEPERDQVLDDVVSWITARL
MAV_4997|M.avium_104                SRRLVECVGSADVELKVYPGLYHEVFNEPEREQVLDDVVGWITARL
MLBr_02603|M.leprae_Br4923          SHRLVECVGSTDVELKVYPGLYHEVFNEPERDQVLEDVVCWILKRL
Mflv_0518|M.gilvum_PYR-GCK          SRQLMECIGSPDAHLKVYPGLYHEVFNEPEKELVLDDVTSWIESKL
Mvan_0150|M.vanbaalenii_PYR-1       SRKLVDRVGSADVHLKEYPGLYHEVFNEPEKALVLDDVTSWIESQL
MSMEG_0220|M.smegmatis_MC2_155      SRLLVDRVASEDVHLKVYPGLYHEVFNEPEQKLVLDDVTSWIVSHL
MAB_4551c|M.abscessus_ATCC_199      SRWLSESAP--DATLKIWNGLYHEIFNEFEKELVLDEVVGWIDARL
TH_3727|M.thermoresistible__bu      SGPLTAELLR-NAKLKTYQGFPHGMMTT-HAEVVNADILEFLRS--
                                    *  *       :. ** : *  *  :.  .   *  ::  ::