For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTAPTRSIDVLLVEDDAGDELITREAFEQNKIANTLHVARDGQEGLDFLYRRGAHELAPRPDLVLLDLNL PKYDGRQLLEQIKSDPELCDIPIVVLTTSAAEEDILRSYKLHANAYVTKPVDLDQFMSAVRQIDEFFVQV VRLPPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3878 | - | - | 100% (146) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_3270 | - | 5e-66 | 84.03% (144) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_1000 | - | 2e-15 | 39.34% (122) | multi-sensor hybrid histidine kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1007 | mprA | 3e-10 | 27.56% (127) | two component response transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0981 | mprA | 9e-10 | 26.77% (127) | two component response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00174 | - | 7e-10 | 26.98% (126) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_4047c | - | 8e-09 | 30.65% (124) | sensory transduction protein RegX3 |
| M. marinum M | MMAR_1265 | - | 5e-65 | 81.25% (144) | two-component transcriptional regulator |
| M. avium 104 | MAV_4240 | - | 3e-64 | 81.25% (144) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_6128 | - | 2e-66 | 87.14% (140) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_2174 | - | 5e-66 | 86.01% (143) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_2623 | - | 2e-64 | 80.56% (144) | two component transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2989 | - | 8e-68 | 86.81% (144) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2174|M.thermoresistible__bu MTPTQEGRAIDVLLVEDDPGDELITREAFEHNKIKNTLHVTRDGEEGLDF
Mvan_2989|M.vanbaalenii_PYR-1 MTPAE--RAIDVLLIEDDPGDELITREAFEHNKIKNTLHVAHDGEEGLDF
MSMEG_6128|M.smegmatis_MC2_155 MTSADETRAIDILLVEDDPGDELITREAFEHNKIKNNLHVAHDGEEGLDF
MMAR_1265|M.marinum_M MTAPG--RPIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDGEEGLDY
MUL_2623|M.ulcerans_Agy99 MTAPG--RPIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDGEEGLDY
MAV_4240|M.avium_104 MTTAG--RAIDILLVEDDPGDELITREAFEHNKLNNRLHVAHDGEEGLNY
Mflv_3878|M.gilvum_PYR-GCK MTAPT--RSIDVLLVEDDAGDELITREAFEQNKIANTLHVARDGQEGLDF
Mb1007|M.bovis_AF2122/97 -------MSVRILVVDDD--RAVRESLRRSLSFNGYSVELAHDGVEALDM
Rv0981|M.tuberculosis_H37Rv -------MSVRILVVDDD--RAVRESLRRSLSFNGYSVELAHDGVEALDM
MLBr_00174|M.leprae_Br4923 ---------MRILAVDDD--RAVRESLRRSLSFNGYSVELANDGVEALEM
MAB_4047c|M.abscessus_ATCC_199 --------MTSVLIVEDE--DSLADPLAFLLRKEGFEATIVNDGPSALAE
:* ::*: : :..** ..*
TH_2174|M.thermoresistible__bu LYRRGRFADAPRPDLILLDLNLPKYDGRQLLEQIKSDPDLSLIPVVVLTT
Mvan_2989|M.vanbaalenii_PYR-1 LYRRGAYTDAPRPDLVLLDLNLPKYDGRQLLEQIKSDPDLSHIPVVVLTT
MSMEG_6128|M.smegmatis_MC2_155 LYRRGPYADAPRPDLILLDLNLPKYDGRQLLEKIKSDEKLCHIPIVVLTT
MMAR_1265|M.marinum_M LYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKSDSELCRIPVVVLTT
MUL_2623|M.ulcerans_Agy99 LYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKFDSELCRIPVVVLTT
MAV_4240|M.avium_104 LYRRGEFADAPRPDLILLDLNLPKYDGRQLLEKIKSDPDLAQIPVVVLTT
Mflv_3878|M.gilvum_PYR-GCK LYRRGAHELAPRPDLVLLDLNLPKYDGRQLLEQIKSDPELCDIPIVVLTT
Mb1007|M.bovis_AF2122/97 IAS-------DRPDALVLDVMMPRLDGLEVCRQLRSTG--DDLPILVLTA
Rv0981|M.tuberculosis_H37Rv IAS-------DRPDALVLDVMMPRLDGLEVCRQLRGTG--DDLPILVLTA
MLBr_00174|M.leprae_Br4923 VAR-------DRPDALVLDVMMPRLDGLEVCRQLRSTG--DDLPILVLTA
MAB_4047c|M.abscessus_ATCC_199 FER-------AGADIVLLDLMLPGMSGTDVCKQLRAK---SSVPVIMVTA
. .* ::**: :* .* :: .::: :*::::*:
TH_2174|M.thermoresistible__bu SSAEEDILRSYQLHANAYVTKPVDLDQFMSAVR-----------------
Mvan_2989|M.vanbaalenii_PYR-1 SSAEEDILRSYKLHANAYVTKPVDLDQFMNAVR-----------------
MSMEG_6128|M.smegmatis_MC2_155 SSAEEDILRSYKLHANAYVTKPVDLDQFMSAVR-----------------
MMAR_1265|M.marinum_M SSAEEDILRSYNLHANAYVTKPVDLDQFMTAVR-----------------
MUL_2623|M.ulcerans_Agy99 SSAEEDILRSYNLHANAYVTKPVDLDQFMTAVR-----------------
MAV_4240|M.avium_104 SSAEEDILKSYKLHANAYVTKPVDLDQFMKAVR-----------------
Mflv_3878|M.gilvum_PYR-GCK SAAEEDILRSYKLHANAYVTKPVDLDQFMSAVR-----------------
Mb1007|M.bovis_AF2122/97 RDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR--TKPEDAAESM
Rv0981|M.tuberculosis_H37Rv RDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR--TKPEDAAESM
MLBr_00174|M.leprae_Br4923 RDSVSERVAGLDAGADDYLPKPFALEELLARIRALLRR--TKPDDAAESV
MAB_4047c|M.abscessus_ATCC_199 RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDSEETASGDG
: : : . . *: *:.** ::: :*
TH_2174|M.thermoresistible__bu -------------------------QIDEFFVQVVRLPTA----------
Mvan_2989|M.vanbaalenii_PYR-1 -------------------------QIDEFFVQVVRLPQF----------
MSMEG_6128|M.smegmatis_MC2_155 -------------------------QIDEFFVQVVRLPQF----------
MMAR_1265|M.marinum_M -------------------------QIDEFFLQVVRLPQS----------
MUL_2623|M.ulcerans_Agy99 -------------------------QIDEFFLQVVRLPQS----------
MAV_4240|M.avium_104 -------------------------QIDEFFVQVVRLPSA----------
Mflv_3878|M.gilvum_PYR-GCK -------------------------QIDEFFVQVVRLPPR----------
Mb1007|M.bovis_AF2122/97 AMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRIL
Rv0981|M.tuberculosis_H37Rv AMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRIL
MLBr_00174|M.leprae_Br4923 AMSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRIL
MAB_4047c|M.abscessus_ATCC_199 VLEAGPVRMDVDRHTVSVNGEAITLPLKEFDLLEYLIRNSGRVLTRGQLI
** : :
TH_2174|M.thermoresistible__bu --------------------------------------------------
Mvan_2989|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6128|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1265|M.marinum_M --------------------------------------------------
MUL_2623|M.ulcerans_Agy99 --------------------------------------------------
MAV_4240|M.avium_104 --------------------------------------------------
Mflv_3878|M.gilvum_PYR-GCK --------------------------------------------------
Mb1007|M.bovis_AF2122/97 EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GEPRLIHTVRGVGYVLRETP
Rv0981|M.tuberculosis_H37Rv EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GEPRLIHTVRGVGYVLRETP
MLBr_00174|M.leprae_Br4923 EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GESRLIHTVRGVGYVLRETP
MAB_4047c|M.abscessus_ATCC_199 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG--
TH_2174|M.thermoresistible__bu -
Mvan_2989|M.vanbaalenii_PYR-1 -
MSMEG_6128|M.smegmatis_MC2_155 -
MMAR_1265|M.marinum_M -
MUL_2623|M.ulcerans_Agy99 -
MAV_4240|M.avium_104 -
Mflv_3878|M.gilvum_PYR-GCK -
Mb1007|M.bovis_AF2122/97 P
Rv0981|M.tuberculosis_H37Rv P
MLBr_00174|M.leprae_Br4923 P
MAB_4047c|M.abscessus_ATCC_199 -