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MTPAERAIDVLLIEDDPGDELITREAFEHNKIKNTLHVAHDGEEGLDFLYRRGAYTDAPRPDLVLLDLNL PKYDGRQLLEQIKSDPDLSHIPVVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQFMNAVRQIDEFFVQV VRLPQF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2989 | - | - | 100% (146) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_4844 | - | 2e-09 | 26.19% (126) | two component transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0831 | - | 5e-09 | 32.56% (129) | two component transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1007 | mprA | 5e-10 | 25.98% (127) | two component response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3270 | - | 4e-77 | 95.21% (146) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv0981 | mprA | 1e-09 | 25.20% (127) | two component response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00174 | - | 2e-09 | 25.40% (126) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_4047c | - | 4e-09 | 31.01% (129) | sensory transduction protein RegX3 |
| M. marinum M | MMAR_1265 | - | 4e-67 | 84.14% (145) | two-component transcriptional regulator |
| M. avium 104 | MAV_4240 | - | 5e-71 | 87.50% (144) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_6128 | - | 8e-73 | 89.19% (148) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_2174 | - | 4e-72 | 90.41% (146) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_2623 | - | 1e-66 | 83.45% (145) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2989|M.vanbaalenii_PYR-1 MTPAER--AIDVLLIEDDPGDELITREAFEHNKIKNTLHVAHDGEEGLDF
Mflv_3270|M.gilvum_PYR-GCK MTPAER--AIDVLLIEDDPGDELITREAFEHNKIKNNLHVAHDGEEGLDF
MSMEG_6128|M.smegmatis_MC2_155 MTSADETRAIDILLVEDDPGDELITREAFEHNKIKNNLHVAHDGEEGLDF
TH_2174|M.thermoresistible__bu MTPTQEGRAIDVLLVEDDPGDELITREAFEHNKIKNTLHVTRDGEEGLDF
MAV_4240|M.avium_104 MTTAGR--AIDILLVEDDPGDELITREAFEHNKLNNRLHVAHDGEEGLNY
MMAR_1265|M.marinum_M MTAPGR--PIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDGEEGLDY
MUL_2623|M.ulcerans_Agy99 MTAPGR--PIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDGEEGLDY
Mb1007|M.bovis_AF2122/97 -------MSVRILVVDDD--RAVRESLRRSLSFNGYSVELAHDGVEALDM
Rv0981|M.tuberculosis_H37Rv -------MSVRILVVDDD--RAVRESLRRSLSFNGYSVELAHDGVEALDM
MLBr_00174|M.leprae_Br4923 ---------MRILAVDDD--RAVRESLRRSLSFNGYSVELANDGVEALEM
MAB_4047c|M.abscessus_ATCC_199 --------MTSVLIVEDE--DSLADPLAFLLRKEGFEATIVNDGPSALAE
:* ::*: : :..** ..*
Mvan_2989|M.vanbaalenii_PYR-1 LYRRGAYTDAPRPDLVLLDLNLPKYDGRQLLEQIKSDPDLSHIPVVVLTT
Mflv_3270|M.gilvum_PYR-GCK LYQRGVYEGAPRPDLILLDLNLPKYDGRQLLEQIKSDADLSHIPVVVLTT
MSMEG_6128|M.smegmatis_MC2_155 LYRRGPYADAPRPDLILLDLNLPKYDGRQLLEKIKSDEKLCHIPIVVLTT
TH_2174|M.thermoresistible__bu LYRRGRFADAPRPDLILLDLNLPKYDGRQLLEQIKSDPDLSLIPVVVLTT
MAV_4240|M.avium_104 LYRRGEFADAPRPDLILLDLNLPKYDGRQLLEKIKSDPDLAQIPVVVLTT
MMAR_1265|M.marinum_M LYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKSDSELCRIPVVVLTT
MUL_2623|M.ulcerans_Agy99 LYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKFDSELCRIPVVVLTT
Mb1007|M.bovis_AF2122/97 IAS-------DRPDALVLDVMMPRLDGLEVCRQLRSTG--DDLPILVLTA
Rv0981|M.tuberculosis_H37Rv IAS-------DRPDALVLDVMMPRLDGLEVCRQLRGTG--DDLPILVLTA
MLBr_00174|M.leprae_Br4923 VAR-------DRPDALVLDVMMPRLDGLEVCRQLRSTG--DDLPILVLTA
MAB_4047c|M.abscessus_ATCC_199 FER-------AGADIVLLDLMLPGMSGTDVCKQLRAK---SSVPVIMVTA
. .* ::**: :* .* :: .::: :*::::*:
Mvan_2989|M.vanbaalenii_PYR-1 SSAEEDILRSYKLHANAYVTKPVDLDQFMNAVR-----------------
Mflv_3270|M.gilvum_PYR-GCK SSAEEDILRSYKLHANAYVTKPVDLDQFMNAVR-----------------
MSMEG_6128|M.smegmatis_MC2_155 SSAEEDILRSYKLHANAYVTKPVDLDQFMSAVR-----------------
TH_2174|M.thermoresistible__bu SSAEEDILRSYQLHANAYVTKPVDLDQFMSAVR-----------------
MAV_4240|M.avium_104 SSAEEDILKSYKLHANAYVTKPVDLDQFMKAVR-----------------
MMAR_1265|M.marinum_M SSAEEDILRSYNLHANAYVTKPVDLDQFMTAVR-----------------
MUL_2623|M.ulcerans_Agy99 SSAEEDILRSYNLHANAYVTKPVDLDQFMTAVR-----------------
Mb1007|M.bovis_AF2122/97 RDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR--TKPEDAAESM
Rv0981|M.tuberculosis_H37Rv RDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR--TKPEDAAESM
MLBr_00174|M.leprae_Br4923 RDSVSERVAGLDAGADDYLPKPFALEELLARIRALLRR--TKPDDAAESV
MAB_4047c|M.abscessus_ATCC_199 RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDSEETASGDG
.: : : . . *: *:.** ::: :*
Mvan_2989|M.vanbaalenii_PYR-1 -------------------------QIDEFFVQVVRLPQF----------
Mflv_3270|M.gilvum_PYR-GCK -------------------------QIDEFFVQVVRLPQF----------
MSMEG_6128|M.smegmatis_MC2_155 -------------------------QIDEFFVQVVRLPQF----------
TH_2174|M.thermoresistible__bu -------------------------QIDEFFVQVVRLPTA----------
MAV_4240|M.avium_104 -------------------------QIDEFFVQVVRLPSA----------
MMAR_1265|M.marinum_M -------------------------QIDEFFLQVVRLPQS----------
MUL_2623|M.ulcerans_Agy99 -------------------------QIDEFFLQVVRLPQS----------
Mb1007|M.bovis_AF2122/97 AMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRIL
Rv0981|M.tuberculosis_H37Rv AMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRIL
MLBr_00174|M.leprae_Br4923 AMSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRIL
MAB_4047c|M.abscessus_ATCC_199 VLEAGPVRMDVDRHTVSVNGEAITLPLKEFDLLEYLIRNSGRVLTRGQLI
** : :
Mvan_2989|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3270|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6128|M.smegmatis_MC2_155 --------------------------------------------------
TH_2174|M.thermoresistible__bu --------------------------------------------------
MAV_4240|M.avium_104 --------------------------------------------------
MMAR_1265|M.marinum_M --------------------------------------------------
MUL_2623|M.ulcerans_Agy99 --------------------------------------------------
Mb1007|M.bovis_AF2122/97 EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GEPRLIHTVRGVGYVLRETP
Rv0981|M.tuberculosis_H37Rv EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GEPRLIHTVRGVGYVLRETP
MLBr_00174|M.leprae_Br4923 EEVWGFDFPTSGNALEVYVGYLRRKTEAD-GESRLIHTVRGVGYVLRETP
MAB_4047c|M.abscessus_ATCC_199 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG--
Mvan_2989|M.vanbaalenii_PYR-1 -
Mflv_3270|M.gilvum_PYR-GCK -
MSMEG_6128|M.smegmatis_MC2_155 -
TH_2174|M.thermoresistible__bu -
MAV_4240|M.avium_104 -
MMAR_1265|M.marinum_M -
MUL_2623|M.ulcerans_Agy99 -
Mb1007|M.bovis_AF2122/97 P
Rv0981|M.tuberculosis_H37Rv P
MLBr_00174|M.leprae_Br4923 P
MAB_4047c|M.abscessus_ATCC_199 -