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MTPAERAIDVLLIEDDPGDELITREAFEHNKIKNNLHVAHDGEEGLDFLYQRGVYEGAPRPDLILLDLNL PKYDGRQLLEQIKSDADLSHIPVVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQFMNAVRQIDEFFVQV VRLPQF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3270 | - | - | 100% (146) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_3878 | - | 5e-66 | 84.03% (144) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_1000 | - | 3e-12 | 31.15% (122) | multi-sensor hybrid histidine kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1007 | mprA | 1e-10 | 25.98% (127) | two component response transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0981 | mprA | 4e-10 | 25.20% (127) | two component response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00174 | - | 3e-09 | 24.60% (126) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3339 | - | 1e-08 | 31.82% (110) | putative sensory transduction protein |
| M. marinum M | MMAR_1265 | - | 5e-68 | 85.52% (145) | two-component transcriptional regulator |
| M. avium 104 | MAV_4240 | - | 7e-69 | 86.11% (144) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_6128 | - | 4e-72 | 89.19% (148) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_2174 | - | 4e-69 | 88.36% (146) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_2623 | - | 2e-67 | 84.83% (145) | two component transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2989 | - | 4e-77 | 95.21% (146) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3270|M.gilvum_PYR-GCK ------MTPAER--AIDVLLIEDDPGDELITREAFEHNKIKNNLHVAHDG
Mvan_2989|M.vanbaalenii_PYR-1 ------MTPAER--AIDVLLIEDDPGDELITREAFEHNKIKNTLHVAHDG
MSMEG_6128|M.smegmatis_MC2_155 ------MTSADETRAIDILLVEDDPGDELITREAFEHNKIKNNLHVAHDG
TH_2174|M.thermoresistible__bu ------MTPTQEGRAIDVLLVEDDPGDELITREAFEHNKIKNTLHVTRDG
MAV_4240|M.avium_104 ------MTTAGR--AIDILLVEDDPGDELITREAFEHNKLNNRLHVAHDG
MMAR_1265|M.marinum_M ------MTAPGR--PIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDG
MUL_2623|M.ulcerans_Agy99 ------MTAPGR--PIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDG
Mb1007|M.bovis_AF2122/97 -------------MSVRILVVDDDRAVRESLRRSLSFNGYS--VELAHDG
Rv0981|M.tuberculosis_H37Rv -------------MSVRILVVDDDRAVRESLRRSLSFNGYS--VELAHDG
MLBr_00174|M.leprae_Br4923 ---------------MRILAVDDDRAVRESLRRSLSFNGYS--VELANDG
MAB_3339|M.abscessus_ATCC_1997 MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFE--VHLAHDG
* ::*: :. : . :.::.**
Mflv_3270|M.gilvum_PYR-GCK EEGLDFLYQRGVYEGAPRPDLILLDLNLPKYDGRQLLEQIKSDADLSHIP
Mvan_2989|M.vanbaalenii_PYR-1 EEGLDFLYRRGAYTDAPRPDLVLLDLNLPKYDGRQLLEQIKSDPDLSHIP
MSMEG_6128|M.smegmatis_MC2_155 EEGLDFLYRRGPYADAPRPDLILLDLNLPKYDGRQLLEKIKSDEKLCHIP
TH_2174|M.thermoresistible__bu EEGLDFLYRRGRFADAPRPDLILLDLNLPKYDGRQLLEQIKSDPDLSLIP
MAV_4240|M.avium_104 EEGLNYLYRRGEFADAPRPDLILLDLNLPKYDGRQLLEKIKSDPDLAQIP
MMAR_1265|M.marinum_M EEGLDYLYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKSDSELCRIP
MUL_2623|M.ulcerans_Agy99 EEGLDYLYQRGKYQQARRPDLILLDLNLPKYDGRQLLEKIKFDSELCRIP
Mb1007|M.bovis_AF2122/97 VEALDMIASD-------RPDALVLDVMMPRLDGLEVCRQLRSTG--DDLP
Rv0981|M.tuberculosis_H37Rv VEALDMIASD-------RPDALVLDVMMPRLDGLEVCRQLRGTG--DDLP
MLBr_00174|M.leprae_Br4923 VEALEMVARD-------RPDALVLDVMMPRLDGLEVCRQLRSTG--DDLP
MAB_3339|M.abscessus_ATCC_1997 RRALDLAREV-------DPDVVILDIGLPGVDGIEVCRQLRVFS--DAY-
..*: ** ::**: :* ** :: .:::
Mflv_3270|M.gilvum_PYR-GCK VVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQFMNAVRQID--------
Mvan_2989|M.vanbaalenii_PYR-1 VVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQFMNAVRQID--------
MSMEG_6128|M.smegmatis_MC2_155 IVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQFMSAVRQID--------
TH_2174|M.thermoresistible__bu VVVLTTSSAEEDILRSYQLHANAYVTKPVDLDQFMSAVRQID--------
MAV_4240|M.avium_104 VVVLTTSSAEEDILKSYKLHANAYVTKPVDLDQFMKAVRQID--------
MMAR_1265|M.marinum_M VVVLTTSSAEEDILRSYNLHANAYVTKPVDLDQFMTAVRQID--------
MUL_2623|M.ulcerans_Agy99 VVVLTTSSAEEDILRSYNLHANAYVTKPVDLDQFMTAVRQID--------
Mb1007|M.bovis_AF2122/97 ILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTK--PE
Rv0981|M.tuberculosis_H37Rv ILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTK--PE
MLBr_00174|M.leprae_Br4923 ILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARIRALLRRTK--PD
MAB_3339|M.abscessus_ATCC_1997 VVMLTARDTEVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPE
:::**: .: : : . . *: *:.**. :.: :* :
Mflv_3270|M.gilvum_PYR-GCK ---------------------------------------EFFVQVVRLPQ
Mvan_2989|M.vanbaalenii_PYR-1 ---------------------------------------EFFVQVVRLPQ
MSMEG_6128|M.smegmatis_MC2_155 ---------------------------------------EFFVQVVRLPQ
TH_2174|M.thermoresistible__bu ---------------------------------------EFFVQVVRLPT
MAV_4240|M.avium_104 ---------------------------------------EFFVQVVRLPS
MMAR_1265|M.marinum_M ---------------------------------------EFFLQVVRLPQ
MUL_2623|M.ulcerans_Agy99 ---------------------------------------EFFLQVVRLPQ
Mb1007|M.bovis_AF2122/97 D-AAESMAMR----FSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIAN
Rv0981|M.tuberculosis_H37Rv D-AAESMAMR----FSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIAN
MLBr_00174|M.leprae_Br4923 D-AAESVAMS----FSDLTLDPVTREVARGQRWISLTRTEFALLEMLIAN
MAB_3339|M.abscessus_ATCC_1997 SPAAVTPELSPPRVFGALRINVDGREVHVGERPVTLTRTEFDVLAALSSR
** : .
Mflv_3270|M.gilvum_PYR-GCK F-------------------------------------------------
Mvan_2989|M.vanbaalenii_PYR-1 F-------------------------------------------------
MSMEG_6128|M.smegmatis_MC2_155 F-------------------------------------------------
TH_2174|M.thermoresistible__bu A-------------------------------------------------
MAV_4240|M.avium_104 A-------------------------------------------------
MMAR_1265|M.marinum_M S-------------------------------------------------
MUL_2623|M.ulcerans_Agy99 S-------------------------------------------------
Mb1007|M.bovis_AF2122/97 PRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKT-EADGEPRLIHTV
Rv0981|M.tuberculosis_H37Rv PRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKT-EADGEPRLIHTV
MLBr_00174|M.leprae_Br4923 PRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKT-EADGESRLIHTV
MAB_3339|M.abscessus_ATCC_1997 PGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTV
Mflv_3270|M.gilvum_PYR-GCK ------------
Mvan_2989|M.vanbaalenii_PYR-1 ------------
MSMEG_6128|M.smegmatis_MC2_155 ------------
TH_2174|M.thermoresistible__bu ------------
MAV_4240|M.avium_104 ------------
MMAR_1265|M.marinum_M ------------
MUL_2623|M.ulcerans_Agy99 ------------
Mb1007|M.bovis_AF2122/97 RGVGYVLRETPP
Rv0981|M.tuberculosis_H37Rv RGVGYVLRETPP
MLBr_00174|M.leprae_Br4923 RGVGYVLRETPP
MAB_3339|M.abscessus_ATCC_1997 RGVGYRMGTGS-