For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TAPGRPIDILLIEDDPGDELITREAFEHNKVNNRLHVAHDGEEGLDYLYQRGKYQQARRPDLILLDLNLP KYDGRQLLEKIKFDSELCRIPVVVLTTSSAEEDILRSYNLHANAYVTKPVDLDQFMTAVRQIDEFFLQVV RLPQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2623 | - | - | 100% (146) | two component transcriptional regulator |
| M. ulcerans Agy99 | MUL_4391 | tcrX | 5e-11 | 26.72% (131) | two component transcriptional regulatory protein TcrX |
| M. ulcerans Agy99 | MUL_4624 | trcR | 1e-10 | 28.68% (129) | two component transcriptional regulator TrcR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1062c | trcR | 1e-10 | 28.68% (129) | two component transcriptional regulator TRCR |
| M. gilvum PYR-GCK | Mflv_3270 | - | 2e-67 | 84.83% (145) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv1033c | trcR | 1e-10 | 28.68% (129) | two component transcriptional regulator TRCR |
| M. leprae Br4923 | MLBr_00174 | - | 8e-08 | 23.02% (126) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3339 | - | 2e-08 | 30.91% (110) | putative sensory transduction protein |
| M. marinum M | MMAR_1265 | - | 2e-80 | 99.32% (146) | two-component transcriptional regulator |
| M. avium 104 | MAV_4240 | - | 3e-68 | 84.25% (146) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_6128 | - | 1e-67 | 86.43% (140) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_2174 | - | 9e-65 | 81.82% (143) | two-component system response regulator |
| M. vanbaalenii PYR-1 | Mvan_2989 | - | 2e-66 | 83.45% (145) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2623|M.ulcerans_Agy99 ---MTAPGR---------------------PIDILLIEDDPGDELITREA
MMAR_1265|M.marinum_M ---MTAPGR---------------------PIDILLIEDDPGDELITREA
Mflv_3270|M.gilvum_PYR-GCK ---MTPAER---------------------AIDVLLIEDDPGDELITREA
Mvan_2989|M.vanbaalenii_PYR-1 ---MTPAER---------------------AIDVLLIEDDPGDELITREA
MSMEG_6128|M.smegmatis_MC2_155 ---MTSADETR-------------------AIDILLVEDDPGDELITREA
TH_2174|M.thermoresistible__bu ---MTPTQEGR-------------------AIDVLLVEDDPGDELITREA
MAV_4240|M.avium_104 ---MTTAGR---------------------AIDILLVEDDPGDELITREA
Mb1062c|M.bovis_AF2122/97 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMA
Rv1033c|M.tuberculosis_H37Rv MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMA
MLBr_00174|M.leprae_Br4923 -------------------------------MRILAVDDDRAVRESLRRS
MAB_3339|M.abscessus_ATCC_1997 ---MDGSSR-----TAAAGPVP--------DYRALVVDDEVPLAEVVASY
* ::*:
MUL_2623|M.ulcerans_Agy99 FEHNKVNNRLHVAHDGEEGLDYLYQRGKYQQARRPDLILLDLNLPKYDGR
MMAR_1265|M.marinum_M FEHNKVNNRLHVAHDGEEGLDYLYQRGKYQQARRPDLILLDLNLPKYDGR
Mflv_3270|M.gilvum_PYR-GCK FEHNKIKNNLHVAHDGEEGLDFLYQRGVYEGAPRPDLILLDLNLPKYDGR
Mvan_2989|M.vanbaalenii_PYR-1 FEHNKIKNTLHVAHDGEEGLDFLYRRGAYTDAPRPDLVLLDLNLPKYDGR
MSMEG_6128|M.smegmatis_MC2_155 FEHNKIKNNLHVAHDGEEGLDFLYRRGPYADAPRPDLILLDLNLPKYDGR
TH_2174|M.thermoresistible__bu FEHNKIKNTLHVTRDGEEGLDFLYRRGRFADAPRPDLILLDLNLPKYDGR
MAV_4240|M.avium_104 FEHNKLNNRLHVAHDGEEGLNYLYRRGEFADAPRPDLILLDLNLPKYDGR
Mb1062c|M.bovis_AF2122/97 LHYEGWD--VEVAHDGQEAIAKFDKVG-------PDVLVLDIMLPDVDGL
Rv1033c|M.tuberculosis_H37Rv LHYEGWD--VEVAHDGQEAIAKFDKVG-------PDVLVLDIMLPDVDGL
MLBr_00174|M.leprae_Br4923 LSFNGYS--VELANDGVEALEMVARDR-------PDALVLDVMMPRLDGL
MAB_3339|M.abscessus_ATCC_1997 LKRESFE--VHLAHDGRRALDLAREVD-------PDVVILDIGLPGVDGI
: : . :.::.** ..: . ** ::**: :* **
MUL_2623|M.ulcerans_Agy99 QLLEKIKFDSELCRIPVVVLTTSSAEEDILRSYNLHANAYVTKPVDLDQF
MMAR_1265|M.marinum_M QLLEKIKSDSELCRIPVVVLTTSSAEEDILRSYNLHANAYVTKPVDLDQF
Mflv_3270|M.gilvum_PYR-GCK QLLEQIKSDADLSHIPVVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQF
Mvan_2989|M.vanbaalenii_PYR-1 QLLEQIKSDPDLSHIPVVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQF
MSMEG_6128|M.smegmatis_MC2_155 QLLEKIKSDEKLCHIPIVVLTTSSAEEDILRSYKLHANAYVTKPVDLDQF
TH_2174|M.thermoresistible__bu QLLEQIKSDPDLSLIPVVVLTTSSAEEDILRSYQLHANAYVTKPVDLDQF
MAV_4240|M.avium_104 QLLEKIKSDPDLAQIPVVVLTTSSAEEDILKSYKLHANAYVTKPVDLDQF
Mb1062c|M.bovis_AF2122/97 EILRRVRE--SDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEEL
Rv1033c|M.tuberculosis_H37Rv EILRRVRE--SDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEEL
MLBr_00174|M.leprae_Br4923 EVCRQLRS--TGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEEL
MAB_3339|M.abscessus_ATCC_1997 EVCRQLR---VFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPREV
:: .::: :.**: .: : : . *: *:.**. :.
MUL_2623|M.ulcerans_Agy99 MTAVRQIDEFFLQVVRLPQS------------------------------
MMAR_1265|M.marinum_M MTAVRQIDEFFLQVVRLPQS------------------------------
Mflv_3270|M.gilvum_PYR-GCK MNAVRQIDEFFVQVVRLPQF------------------------------
Mvan_2989|M.vanbaalenii_PYR-1 MNAVRQIDEFFVQVVRLPQF------------------------------
MSMEG_6128|M.smegmatis_MC2_155 MSAVRQIDEFFVQVVRLPQF------------------------------
TH_2174|M.thermoresistible__bu MSAVRQIDEFFVQVVRLPTA------------------------------
MAV_4240|M.avium_104 MKAVRQIDEFFVQVVRLPSA------------------------------
Mb1062c|M.bovis_AF2122/97 VARLRGLLRRSSHL-ERPADEALRVG------DLTLDGASREVTRDGTPI
Rv1033c|M.tuberculosis_H37Rv VARLRGLLRRSSHL-ERPADEALRVG------DLTLDGASREVTRDGTPI
MLBr_00174|M.leprae_Br4923 LARIRALLRRTKPD-DAAESVAMSFS------DLTLDPVTREVARGQRWI
MAB_3339|M.abscessus_ATCC_1997 VARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINVDGREVHVGERPV
: :* : . .
MUL_2623|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1265|M.marinum_M --------------------------------------------------
Mflv_3270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2989|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6128|M.smegmatis_MC2_155 --------------------------------------------------
TH_2174|M.thermoresistible__bu --------------------------------------------------
MAV_4240|M.avium_104 --------------------------------------------------
Mb1062c|M.bovis_AF2122/97 SLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLR
Rv1033c|M.tuberculosis_H37Rv SLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLR
MLBr_00174|M.leprae_Br4923 SLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLR
MAB_3339|M.abscessus_ATCC_1997 TLTRTEFDVLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLR
MUL_2623|M.ulcerans_Agy99 ----------------------------
MMAR_1265|M.marinum_M ----------------------------
Mflv_3270|M.gilvum_PYR-GCK ----------------------------
Mvan_2989|M.vanbaalenii_PYR-1 ----------------------------
MSMEG_6128|M.smegmatis_MC2_155 ----------------------------
TH_2174|M.thermoresistible__bu ----------------------------
MAV_4240|M.avium_104 ----------------------------
Mb1062c|M.bovis_AF2122/97 KKI-DSDREP-MIHTVRGIGYMLRPPE-
Rv1033c|M.tuberculosis_H37Rv KKI-DSDREP-MIHTVRGIGYMLRPPE-
MLBr_00174|M.leprae_Br4923 RKT-EADGESRLIHTVRGVGYVLRETPP
MAB_3339|M.abscessus_ATCC_1997 QKLGDSPSQPRYVMTVRGVGYRMGTGS-