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MSPRPRSAGSQFRFGLLDGIVNTRVSPTLLPSAAMLTASATGADSFWVGDHINSLVPRSVATPEHLGLAA KLVPKVDAILEPWTMLGHLAARHRGRLRFGVGVTDASRRHPAVTAQAAATLHLLTRGRAILGIGVGEREG NEPYGVEWTKPVARFVEALATIRALWESGGEPVTRESDYFPLRHAVFDLPPYKGRWPEIWVAAHGPRMLR ATGRYADGWVPFVISRPADYARALDAVRTAASDNGRDPMAIVPAVNRTVVTGRTRADVDEALDSVIVKSV ALAAPAEAWARHGVEHPLGSDFSGVQDLVPQMIDKEAALAYTASVPASLMKEICFHGTADEVLDQVAEWR DHGLRYLLVINGSQLNPKLRKGVSATLPYNRVLRGLKKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3380 | - | - | 100% (389) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_2493 | - | 6e-57 | 40.51% (311) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4402 | - | 2e-55 | 39.50% (319) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2975c | - | 1e-163 | 71.35% (377) | oxidoreductase |
| M. tuberculosis H37Rv | Rv2951c | - | 1e-163 | 71.35% (377) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 1e-161 | 70.71% (379) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0968c | - | 6e-16 | 32.20% (236) | luciferase-like hypothetical protein |
| M. marinum M | MMAR_1758 | - | 1e-162 | 72.44% (381) | ketoreductase |
| M. avium 104 | MAV_0066 | - | 5e-53 | 38.29% (316) | hypothetical protein MAV_0066 |
| M. smegmatis MC2 155 | MSMEG_6454 | - | 2e-17 | 34.29% (210) | hypothetical protein MSMEG_6454 |
| M. thermoresistible (build 8) | TH_2487 | - | 1e-17 | 33.17% (202) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3202 | - | 2e-20 | 33.20% (244) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5695 | - | 2e-16 | 33.81% (210) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2975c|M.bovis_AF2122/97 ------MGG--LRFGFVDALVHS---------------RLPPTLPARSSM
Rv2951c|M.tuberculosis_H37Rv ------MGG--LRFGFVDALVHS---------------RLPPTLPARSSM
MLBr_00131|M.leprae_Br4923 ------MAG--FRFGFVDALVHT---------------LFPPSLPARASI
MMAR_1758|M.marinum_M ---MKKSSG--FRYGFVDAPVHS---------------RLPPSMIARSSM
Mflv_3380|M.gilvum_PYR-GCK MSPRPRSAGSQFRFGLLDGIVNT---------------RVSPTLLPSAAM
MAV_0066|M.avium_104 ----------------MTVQPAA---------------FLRTTLPLDLSR
MSMEG_6454|M.smegmatis_MC2_155 -----------MRFAFKTSPQN------------------TTWADMLAIW
Mvan_5695|M.vanbaalenii_PYR-1 -----------MRFAFKTSPQN------------------TAWSDMLSVW
MUL_3202|M.ulcerans_Agy99 -----------MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVS
MAB_0968c|M.abscessus_ATCC_199 -----------MRFSIWGQTNQS-------------------WADLLDIA
TH_2487|M.thermoresistible__bu ------------MTDYGHDLLFG------------------TFVTPSNHP
Mb2975c|M.bovis_AF2122/97 AAATVMG-ADSYWVGDHLNALVPRSIATS-----EYLGIAAKFVPKIDAN
Rv2951c|M.tuberculosis_H37Rv AAATVMG-ADSYWVGDHLNALVPRSIATS-----EYLGIAAKFVPKIDAN
MLBr_00131|M.leprae_Br4923 VSGAVLG-ADSYWVGDHLNALVPRSVATP-----KYLGVAAKVVPKIDAN
MMAR_1758|M.marinum_M MAGAVMG-ADSYWIGDHLNALVPRSVATP-----EFLGLGARLVPKVDAN
Mflv_3380|M.gilvum_PYR-GCK LTASATG-ADSFWVGDHINSLVPRSVATP-----EHLGLAAKLVPKVDAI
MAV_0066|M.avium_104 LDEFDSGRYHSVWLPDHMVSFWPDSIWAP-----EFTDLATASASPHRHL
MSMEG_6454|M.smegmatis_MC2_155 KAADNIDVFESGWTFDHFYPIFSD---------------------SAGPC
Mvan_5695|M.vanbaalenii_PYR-1 KAADDIDVFESGWTFDHFYPIFSD---------------------PSGPC
MUL_3202|M.ulcerans_Agy99 TLAESYG-FDSVWLCDHFLTLSPDDYVTQAGISGEHERRDGRDRPGTMPL
MAB_0968c|M.abscessus_ATCC_199 QYADDGT-WRAFYAADHFMSHADTAEERT-------------------DF
TH_2487|M.thermoresistible__bu PHHPVEQAVVADRAGLDLVTFQDHPYVAK--------------------Y
: .: .
Mb2975c|M.bovis_AF2122/97 YEPWTMLGNLAFG-LPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGR
Rv2951c|M.tuberculosis_H37Rv YEPWTMLGNLAFG-LPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGR
MLBr_00131|M.leprae_Br4923 YEPWTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGK
MMAR_1758|M.marinum_M YEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGR
Mflv_3380|M.gilvum_PYR-GCK LEPWTMLGHLAAR-HRGRLRFGVGVTDASRRHPAVTAQAAATLHLLTRGR
MAV_0066|M.avium_104 DG---LAVAAAAAVLTERVPLVSAVVDTVRRHPALLAQTALTLDHLSKGR
MSMEG_6454|M.smegmatis_MC2_155 LEGWTTLTALAQA--TERLRVGVLVTGIHYRHPAVLANMAAALDIISNGR
Mvan_5695|M.vanbaalenii_PYR-1 LEGWVTLTALAQA--TTRLRVGVLVTGIHYRHPAVLANMASALDIVSDGR
MUL_3202|M.ulcerans_Agy99 LEAWTALSALARD--TTYIRLGTSVLCNSYRHPAVLAKMAATLDIISEGR
MAB_0968c|M.abscessus_ATCC_199 HEATALFAALAAA--TSRIRLAPLVLSMTFRHPAVLANWAATVDHVSQGR
TH_2487|M.thermoresistible__bu HDTWTLMSYAAAR--TQRVRLSANVANLPLRPPAVLARSAAGLDLLSGGR
* : . * * **: *. * :. :: *:
Mb2975c|M.bovis_AF2122/97 AILGIGVGEREGN-EPYGVEWT---KPVARFEEALATIRALWNSNGE-LI
Rv2951c|M.tuberculosis_H37Rv AILGIGVGEREGN-EPYGVEWT---KPVARFEEALATIRALWNSNGE-LI
MLBr_00131|M.leprae_Br4923 AMLGIGVGEREGN-EPYGVEWT---KPVARFQEALATIRALWDSNGE-LV
MMAR_1758|M.marinum_M AILGIGVGEREGN-EPYGVEWS---KPVARFEEGLATIRALWDSNGA-LV
Mflv_3380|M.gilvum_PYR-GCK AILGIGVGEREGN-EPYGVEWT---KPVARFVEALATIRALWESGGE-PV
MAV_0066|M.avium_104 FILGLGSGESENT-VPYGFDFA---RPVSRFEEALRVIRLLWDTDG--PV
MSMEG_6454|M.smegmatis_MC2_155 LELGIGAGWNEEESGAYGIELGSIKERFDRFEEACEVLKGLLTQET---T
Mvan_5695|M.vanbaalenii_PYR-1 LELGIGAGWNEEESGAYGIELGSIKERFDRFEEACQVLKGLLSQDT---T
MUL_3202|M.ulcerans_Agy99 LDLGLGAGWFEREFTAYGIPFLPVGDRVTGLGEALEVITAIWTQPD---P
MAB_0968c|M.abscessus_ATCC_199 FTLGLGAGWQENEHQRYGLELGKPGARVDRFSEGLQVITGLLNEPV---T
TH_2487|M.thermoresistible__bu VELGLGAGAFWDGVVAMGGERRSPGAAIKALEEAIAVIRGIWDVDAAGVL
**:* * * . : *. .: :
Mb2975c|M.bovis_AF2122/97 SRESPYFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLRATGRYADAWIPI
Rv2951c|M.tuberculosis_H37Rv SRESPYFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLRATGRYADAWIPI
MLBr_00131|M.leprae_Br4923 SRESQFFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLQATGRYADAWIPI
MMAR_1758|M.marinum_M TRESPYFPLRNALFDLPPYKGKWPEIWVAAHGP-RMLRATGRYADAWVPI
Mflv_3380|M.gilvum_PYR-GCK TRESDYFPLRHAVFDLPPYKGRWPEIWVAAHGP-RMLRATGRYADGWVPF
MAV_0066|M.avium_104 DFNGEFYSLHQARLDTEPYHDRLPPIWIGASGP-RMLDIAGRYADGWWPA
MSMEG_6454|M.smegmatis_MC2_155 TFDGKFYQLKDARNEPKGPQQPHPPFCIGGSGEKRTLRITAKYADHWN-F
Mvan_5695|M.vanbaalenii_PYR-1 TFDGKFYQLKDARNEPKGPQRPHPPICIGGSGEKRTLRITAQYADHWN-F
MUL_3202|M.ulcerans_Agy99 VYSGRFYTLDGAICDPPPVQTPHPPLWVGGEGD-RVHRIAARSAQGIN-V
MAB_0968c|M.abscessus_ATCC_199 TVDGQYYRLAEGICEPKPLQRPLP-ILIGATQP-RMLALTARYAHEWN--
TH_2487|M.thermoresistible__bu DVDGAHYRIRGAKRGPAP--AHRISIWIGGYGP-RMLGLVGRLADGWLPS
.. .: : . : :.. * ..: *.
Mb2975c|M.bovis_AF2122/97 VVVRP---SDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVE
Rv2951c|M.tuberculosis_H37Rv VVVRP---SDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVE
MLBr_00131|M.leprae_Br4923 VLVRP---TDYSCALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVD
MMAR_1758|M.marinum_M VIIRP---TDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVD
Mflv_3380|M.gilvum_PYR-GCK VISRP---ADYARALDAVRTAASDNGRDPMAIVPAVNRTVVTGRTRADVD
MAV_0066|M.avium_104 GAWTP---EHYAEMLGAVRVSAERAGRDPMAITPCFIQVCLIGEDDDALA
MSMEG_6454|M.smegmatis_MC2_155 VGGTP---EEFARKRDVLAAHCADLGRDPKEIT-----------------
Mvan_5695|M.vanbaalenii_PYR-1 VGGPP---EEFARKRDVLARHCADIGRDPGEIS-----------------
MUL_3202|M.ulcerans_Agy99 RWWLP---QKVKQRKDFLAQTCATAQRDPTTLR-----------------
MAB_0968c|M.abscessus_ATCC_199 QWSSP---GTFREVSGRLDAAAEKIGRDPATIWR----------------
TH_2487|M.thermoresistible__bu LQYLSGGVSDLTAMNQRIDDAAVAAGRDPRQIR-----------------
. : . *** :
Mb2975c|M.bovis_AF2122/97 EALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVL
Rv2951c|M.tuberculosis_H37Rv EALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVL
MLBr_00131|M.leprae_Br4923 EALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVV
MMAR_1758|M.marinum_M EALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVL
Mflv_3380|M.gilvum_PYR-GCK EALDSVIVKSVALAAPAEAWARHGVEHPLGSDFSGVQDLVPQMIDKEAAL
MAV_0066|M.avium_104 EILRAPLVKAFLLQVSAKTLGEFGFEHPMGDGWRGFQDIDPAALGRDRIV
MSMEG_6454|M.smegmatis_MC2_155 ----------------------LSAHVRLGEDR-----------------
Mvan_5695|M.vanbaalenii_PYR-1 ----------------------LSAHIRLGADL-----------------
MUL_3202|M.ulcerans_Agy99 ----------------------FSVTALLAPTDSAEQEAQ----------
MAB_0968c|M.abscessus_ATCC_199 -----------------------STQARVIVTDGPQSEAR----------
TH_2487|M.thermoresistible__bu --------------------------------------------------
Mb2975c|M.bovis_AF2122/97 SYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL
Rv2951c|M.tuberculosis_H37Rv SYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL
MLBr_00131|M.leprae_Br4923 SYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSL
MMAR_1758|M.marinum_M SYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL
Mflv_3380|M.gilvum_PYR-GCK AYTASVPASLMKEICFHGTADEVLDQVAEWRDHGLRYLLVINGSQLNPKL
MAV_0066|M.avium_104 EFLHRVRPEMVLAVVPHGTPKQVAKIVKSYVDAGLRVPKILDYG-AMAGL
MSMEG_6454|M.smegmatis_MC2_155 -----DYAKVIDEAAALGAEGLDLAIIYLPPPYDPAVLEPLAQAIRDSGQ
Mvan_5695|M.vanbaalenii_PYR-1 -----DYDKVIEEAAALGAEGLELAIVYLPLPHDPAVLEPLADKIRASGL
MUL_3202|M.ulcerans_Agy99 --IRTEFSAVPYDGLIVGPADRCIERINEYYESGVDTFLFTIPDVARSDL
MAB_0968c|M.abscessus_ATCC_199 ---AAETAAASPIPVLYGTAERIAEQMAPWTQEGVDEVILPDHLLGSGSA
TH_2487|M.thermoresistible__bu ------------RLLNVGGQPSADELADIALSHGISAFILASDDTATTER
* .
Mb2975c|M.bovis_AF2122/97 RKTVTAVLPHAKVLRGLKKL-----
Rv2951c|M.tuberculosis_H37Rv RKTVTAVLPHAKVLRGLKKL-----
MLBr_00131|M.leprae_Br4923 RKTVSALLPHARVLRGLKKL-----
MMAR_1758|M.marinum_M RKTVTAVLPHAKVLRGLKKL-----
Mflv_3380|M.gilvum_PYR-GCK RKGVSATLPYNRVLRGLKKL-----
MAV_0066|M.avium_104 SHAQSSAANVRATEDELMRLCGDGS
MSMEG_6454|M.smegmatis_MC2_155 LTAA---------------------
Mvan_5695|M.vanbaalenii_PYR-1 LDSKAR-------------------
MUL_3202|M.ulcerans_Agy99 IHTVGQEVLPAFD------------
MAB_0968c|M.abscessus_ATCC_199 RRDAYDALAQALRPLSNETD-----
TH_2487|M.thermoresistible__bu FAAEVAPAVRELVTAQR--------