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TVQPAAFLRTTLPLDLSRLDEFDSGRYHSVWLPDHMVSFWPDSIWAPEFTDLATASASPHRHLDGLAVAA AAAVLTERVPLVSAVVDTVRRHPALLAQTALTLDHLSKGRFILGLGSGESENTVPYGFDFARPVSRFEEA LRVIRLLWDTDGPVDFNGEFYSLHQARLDTEPYHDRLPPIWIGASGPRMLDIAGRYADGWWPAGAWTPEH YAEMLGAVRVSAERAGRDPMAITPCFIQVCLIGEDDDALAEILRAPLVKAFLLQVSAKTLGEFGFEHPMG DGWRGFQDIDPAALGRDRIVEFLHRVRPEMVLAVVPHGTPKQVAKIVKSYVDAGLRVPKILDYGAMAGLS HAQSSAANVRATEDELMRLCGDGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0066 | - | - | 100% (375) | hypothetical protein MAV_0066 |
| M. avium 104 | MAV_4445 | - | 1e-18 | 26.51% (298) | hypothetical protein MAV_4445 |
| M. avium 104 | MAV_0169 | - | 1e-17 | 34.60% (211) | hypothetical protein MAV_0169 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2975c | - | 3e-56 | 38.92% (316) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2493 | - | 1e-176 | 79.19% (370) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2951c | - | 3e-56 | 38.92% (316) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 5e-55 | 36.55% (342) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0968c | - | 3e-25 | 36.74% (215) | luciferase-like hypothetical protein |
| M. marinum M | MMAR_1758 | - | 2e-56 | 39.24% (316) | ketoreductase |
| M. smegmatis MC2 155 | MSMEG_6454 | - | 2e-20 | 35.47% (234) | hypothetical protein MSMEG_6454 |
| M. thermoresistible (build 8) | TH_2487 | - | 3e-22 | 35.40% (226) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3202 | - | 3e-21 | 31.85% (248) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0698 | - | 3e-18 | 35.23% (193) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0066|M.avium_104 -------MTVQPAAFLRT----------------TLPLDLSRLDEFDSGR
Mflv_2493|M.gilvum_PYR-GCK -------MKVQPAAFLRT----------------TLPLDLGQLAQLDSGR
Mb2975c|M.bovis_AF2122/97 ---MGGLRFGFVDALVHS----------------RLPPTLPARSSMAAAT
Rv2951c|M.tuberculosis_H37Rv ---MGGLRFGFVDALVHS----------------RLPPTLPARSSMAAAT
MLBr_00131|M.leprae_Br4923 ---MAGFRFGFVDALVHT----------------LFPPSLPARASIVSGA
MMAR_1758|M.marinum_M MKKSSGFRYGFVDAPVHS----------------RLPPSMIARSSMMAGA
MSMEG_6454|M.smegmatis_MC2_155 ------MRFAFKTSPQN------------------TTWADMLAIWKAADN
MUL_3202|M.ulcerans_Agy99 ------MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAES
MAB_0968c|M.abscessus_ATCC_199 ------MRFSIWGQTNQS-------------------WADLLDIAQYADD
TH_2487|M.thermoresistible__bu -------MTDYGHDLLFG------------------TFVTPSNHPPHHPV
Mvan_0698|M.vanbaalenii_PYR-1 ---MAELKLGYKASAEQF-------------------APRELVELAVAAE
MAV_0066|M.avium_104 YH---SVWLPDHMVSFWPDSIWAPEFTD---LATASA---SPHRHLDGLA
Mflv_2493|M.gilvum_PYR-GCK YH---SIWLPDHMVSFWPDSIWTPEFTD---LAVASP---SPHRHLDGMA
Mb2975c|M.bovis_AF2122/97 VMGADSYWVGDHLNALVPRSIATSEYLG---IAAKFVPKIDANYEPWTML
Rv2951c|M.tuberculosis_H37Rv VMGADSYWVGDHLNALVPRSIATSEYLG---IAAKFVPKIDANYEPWTML
MLBr_00131|M.leprae_Br4923 VLGADSYWVGDHLNALVPRSVATPKYLG---VAAKVVPKIDANYEPWTML
MMAR_1758|M.marinum_M VMGADSYWIGDHLNALVPRSVATPEFLG---LGARLVPKVDANYEPWTML
MSMEG_6454|M.smegmatis_MC2_155 IDVFESGWTFDHFYPIFSD---------------------SAGPCLEGWT
MUL_3202|M.ulcerans_Agy99 YG-FDSVWLCDHFLTLSPDDYVTQAGISGEHERRDGRDRPGTMPLLEAWT
MAB_0968c|M.abscessus_ATCC_199 GT-WRAFYAADHFMSHADTAEER-------------------TDFHEATA
TH_2487|M.thermoresistible__bu EQAVVADRAGLDLVTFQDHP--------------------YVAKYHDTWT
Mvan_0698|M.vanbaalenii_PYR-1 EHGMDSATVSDHFQPWRHEG----------------------GHAPFSLA
: .: .
MAV_0066|M.avium_104 VAAAAAVLTERVPLVSAVVDTVRRH-PALLAQTALTLDHLSKGRFILGLG
Mflv_2493|M.gilvum_PYR-GCK VAAAAAVLTENVPLATSVVDTVRRH-PASLAQSALTIDHLSKGRFILGLG
Mb2975c|M.bovis_AF2122/97 GNLAFG-LPSRLRLGVCVTDAGRRN-PAVTAQAAATLHLLTRGRAILGIG
Rv2951c|M.tuberculosis_H37Rv GNLAFG-LPSRLRLGVCVTDAGRRN-PAVTAQAAATLHLLTRGRAILGIG
MLBr_00131|M.leprae_Br4923 GNLAAGNRLNGLRLGVCVTDAGRRN-PAVTAQAAATLHLLTRGKAMLGIG
MMAR_1758|M.marinum_M GNLAAGNRINRLRLGVCVTDVGRRN-PAVTAQAAATVHLLTRGRAILGIG
MSMEG_6454|M.smegmatis_MC2_155 TLTALAQATERLRVGVLVTGIHYRH-PAVLANMAAALDIISNGRLELGIG
MUL_3202|M.ulcerans_Agy99 ALSALARDTTYIRLGTSVLCNSYRH-PAVLAKMAATLDIISEGRLDLGLG
MAB_0968c|M.abscessus_ATCC_199 LFAALAAATSRIRLAPLVLSMTFRH-PAVLANWAATVDHVSQGRFTLGLG
TH_2487|M.thermoresistible__bu LMSYAAARTQRVRLSANVANLPLRP-PAVLARSAAGLDLLSGGRVELGLG
Mvan_0698|M.vanbaalenii_PYR-1 WMTAVGERTKRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPGRIFLGVG
. : : * * ** *. : : *: **:*
MAV_0066|M.avium_104 SGESENTV--PYGFDFA---RPVSRFEEALRVIRLLWDTDG--PVDFNGE
Mflv_2493|M.gilvum_PYR-GCK SGERENIL--PYGFDFR---SPVGRFEEALHVIRLLWDTEG--PVDFDGR
Mb2975c|M.bovis_AF2122/97 VGEREGNE--PYGVEWT---KPVARFEEALATIRALWNSNGE-LISRESP
Rv2951c|M.tuberculosis_H37Rv VGEREGNE--PYGVEWT---KPVARFEEALATIRALWNSNGE-LISRESP
MLBr_00131|M.leprae_Br4923 VGEREGNE--PYGVEWT---KPVARFQEALATIRALWDSNGE-LVSRESQ
MMAR_1758|M.marinum_M VGEREGNE--PYGVEWS---KPVARFEEGLATIRALWDSNGA-LVTRESP
MSMEG_6454|M.smegmatis_MC2_155 AGWNEEESG-AYGIELGSIKERFDRFEEACEVLKGLLTQET---TTFDGK
MUL_3202|M.ulcerans_Agy99 AGWFEREFT-AYGIPFLPVGDRVTGLGEALEVITAIWTQPD---PVYSGR
MAB_0968c|M.abscessus_ATCC_199 AGWQENEHQ-RYGLELGKPGARVDRFSEGLQVITGLLNEPV---TTVDGQ
TH_2487|M.thermoresistible__bu AGAFWDGVV-AMGGERRSPGAAIKALEEAIAVIRGIWDVDAAGVLDVDGA
Mvan_0698|M.vanbaalenii_PYR-1 TGEALNEIATGYEGDWPEFKERYARLRESVRLMRDLWLGDR---VDFEGE
* : *. : : ..
MAV_0066|M.avium_104 FYSLHQARLDTEPYHDRLPPIWIGASGP-RMLDIAGRYADGWWPAGAWTP
Mflv_2493|M.gilvum_PYR-GCK FYRLRHARLDTEPYEGRRPPIWVGASGP-RSLDIAGRYADGWWPAGAWTP
Mb2975c|M.bovis_AF2122/97 YFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLRATGRYADAWIPIVVVRP
Rv2951c|M.tuberculosis_H37Rv YFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLRATGRYADAWIPIVVVRP
MLBr_00131|M.leprae_Br4923 FFPLHNALFDLPPYRGKWPEIWVAAHGP-RMLQATGRYADAWIPIVLVRP
MMAR_1758|M.marinum_M YFPLRNALFDLPPYKGKWPEIWVAAHGP-RMLRATGRYADAWVPIVIIRP
MSMEG_6454|M.smegmatis_MC2_155 FYQLKDARNEPKGPQQPHPPFCIGGSGEKRTLRITAKYADHWN-FVGGTP
MUL_3202|M.ulcerans_Agy99 FYTLDGAICDPPPVQTPHPPLWVGGEGD-RVHRIAARSAQGIN-VRWWLP
MAB_0968c|M.abscessus_ATCC_199 YYRLAEGICEPKPLQRPLP-ILIGATQP-RMLALTARYAHEWN--QWSSP
TH_2487|M.thermoresistible__bu HYRIRGAKRGPAP--AHRISIWIGGYGP-RMLGLVGRLADGWLPSLQYLS
Mvan_0698|M.vanbaalenii_PYR-1 YYKTKGASIYDVP--EGGIPIYIAAGGP-QVAKYAGRAGDGFICTSGKGE
.: . : :.. : ..: ..
MAV_0066|M.avium_104 ---EHYAEMLGAVRVSAERAGRDPMAITPCFIQVCLIGEDDDALAEILRA
Mflv_2493|M.gilvum_PYR-GCK ---DDYAEKLTRVRSSAERAGRDPQQITPCFIQVCLMGRDDAALAEILQA
Mb2975c|M.bovis_AF2122/97 ---SDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALES
Rv2951c|M.tuberculosis_H37Rv ---SDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALES
MLBr_00131|M.leprae_Br4923 ---TDYSCALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVDEALDS
MMAR_1758|M.marinum_M ---TDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDS
MSMEG_6454|M.smegmatis_MC2_155 ---EEFARKRDVLAAHCADLGRDPKEIT----------------------
MUL_3202|M.ulcerans_Agy99 ---QKVKQRKDFLAQTCATAQRDPTTLR----------------------
MAB_0968c|M.abscessus_ATCC_199 ---GTFREVSGRLDAAAEKIGRDPATIWR---------------------
TH_2487|M.thermoresistible__bu GGVSDLTAMNQRIDDAAVAAGRDPRQIRR---------------------
Mvan_0698|M.vanbaalenii_PYR-1 E--LYKDKLIPAMREGAEAAGKNPDDIDR---------------------
: . ::* :
MAV_0066|M.avium_104 PLVKAFLLQVSAKTLGEFGFEHPMGDGWRGFQDIDPAALGRDRIVEFLHR
Mflv_2493|M.gilvum_PYR-GCK PLVKSFLLQVSAEVLRRFGFEHPMGPDWNGFHDIDPAVLTRERIVEFLDR
Mb2975c|M.bovis_AF2122/97 VVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAK
Rv2951c|M.tuberculosis_H37Rv VVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAK
MLBr_00131|M.leprae_Br4923 VLVRMIALGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAK
MMAR_1758|M.marinum_M VIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAK
MSMEG_6454|M.smegmatis_MC2_155 -LSAHVRLGEDRDYAKVIDEAAALGAEGLDLAIIYLPP-------PYDPA
MUL_3202|M.ulcerans_Agy99 -FSVTALLAPTDSAEQEAQIRTEFSAVPYDGLIVGPADRCIERINEYYES
MAB_0968c|M.abscessus_ATCC_199 ---STQARVIVTDGPQSEARAAETAAASPIPVLYGTAERIAEQMAPWTQE
TH_2487|M.thermoresistible__bu ------LLNVGGQPSADELADIALSHGISAFILASDDTATTERFAAEVAP
Mvan_0698|M.vanbaalenii_PYR-1 --MIEIKISYDTDPELALENTRFWAPLSLTAEQKHSIDDPIEMEKAADAL
. .
MAV_0066|M.avium_104 VRPEMVLAVVPHGTPKQVAKIVKSYVDAGLRVPKILDYGAMAGLSHAQSS
Mflv_2493|M.gilvum_PYR-GCK VQPEMVLAMVPHGTPKQVARVIKDYVDVGLRVPKILDYAAMAGGGYAAQS
Mb2975c|M.bovis_AF2122/97 VPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVT
Rv2951c|M.tuberculosis_H37Rv VPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVT
MLBr_00131|M.leprae_Br4923 VPAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVS
MMAR_1758|M.marinum_M VPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVT
MSMEG_6454|M.smegmatis_MC2_155 VLEPLAQAIRDSGQLTAA--------------------------------
MUL_3202|M.ulcerans_Agy99 GVDTFLFTIPDVARSDLIHTVGQEVLPAFD--------------------
MAB_0968c|M.abscessus_ATCC_199 GVDEVILPDHLLGSGSARRDAYDALAQALRPLSNETD-------------
TH_2487|M.thermoresistible__bu AVRELVTAQR----------------------------------------
Mvan_0698|M.vanbaalenii_PYR-1 PIEQVAKRWIVASDPDEAVAKVKDYVDWGLNHLVFHAPGHDQRRFLELFR
.
MAV_0066|M.avium_104 AANVRATEDELMRLCGDGS
Mflv_2493|M.gilvum_PYR-GCK AGNVREAEDELLRLCG---
Mb2975c|M.bovis_AF2122/97 AVLPHAKVLRGLKKL----
Rv2951c|M.tuberculosis_H37Rv AVLPHAKVLRGLKKL----
MLBr_00131|M.leprae_Br4923 ALLPHARVLRGLKKL----
MMAR_1758|M.marinum_M AVLPHAKVLRGLKKL----
MSMEG_6454|M.smegmatis_MC2_155 -------------------
MUL_3202|M.ulcerans_Agy99 -------------------
MAB_0968c|M.abscessus_ATCC_199 -------------------
TH_2487|M.thermoresistible__bu -------------------
Mvan_0698|M.vanbaalenii_PYR-1 RDLEPRLRKLG--------