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VRFAFKTSPQNTAWSDMLSVWKAADDIDVFESGWTFDHFYPIFSDPSGPCLEGWVTLTALAQATTRLRVG VLVTGIHYRHPAVLANMASALDIVSDGRLELGIGAGWNEEESGAYGIELGSIKERFDRFEEACQVLKGLL SQDTTTFDGKFYQLKDARNEPKGPQRPHPPICIGGSGEKRTLRITAQYADHWNFVGGPPEEFARKRDVLA RHCADIGRDPGEISLSAHIRLGADLDYDKVIEEAAALGAEGLELAIVYLPLPHDPAVLEPLADKIRASGL LDSKAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5695 | - | - | 100% (286) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_3077 | - | 2e-42 | 40.99% (222) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5062 | - | 8e-41 | 39.81% (216) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 6e-40 | 44.22% (199) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1117 | - | 1e-153 | 91.52% (283) | luciferase family protein |
| M. tuberculosis H37Rv | Rv1855c | - | 6e-40 | 44.22% (199) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 5e-14 | 29.72% (212) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4496c | - | 1e-146 | 87.32% (276) | luciferase-like monooxygenase |
| M. marinum M | MMAR_5411 | - | 1e-139 | 81.21% (282) | hypothetical protein MMAR_5411 |
| M. avium 104 | MAV_0169 | - | 1e-142 | 84.10% (283) | hypothetical protein MAV_0169 |
| M. smegmatis MC2 155 | MSMEG_6454 | - | 1e-147 | 87.19% (281) | hypothetical protein MSMEG_6454 |
| M. thermoresistible (build 8) | TH_4285 | - | 1e-144 | 85.36% (280) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_5034 | - | 1e-138 | 81.21% (282) | hypothetical protein MUL_5034 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1886c|M.bovis_AF2122/97 ---MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFY
Rv1855c|M.tuberculosis_H37Rv ---MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFY
Mvan_5695|M.vanbaalenii_PYR-1 ---MRFAFKTSPQNTAWSD-------MLSVWKAADDIDVFESGWTFDHFY
Mflv_1117|M.gilvum_PYR-GCK ---MRFAFKTSPQNTTWSD-------MLTVWKAADDIDVFESGWTFDHFY
MAB_4496c|M.abscessus_ATCC_199 ---MRFAFKTSPQNTTWDD-------MLAIWKVADDIEVFESGWTFDHFY
MSMEG_6454|M.smegmatis_MC2_155 ---MRFAFKTSPQNTTWAD-------MLAIWKAADNIDVFESGWTFDHFY
TH_4285|M.thermoresistible__bu ---MQFGFKTSPQNTTWQD-------MLSVWRAADDIDVFESGWTFDHFY
MMAR_5411|M.marinum_M ---MRFAFKTSPQNTTWEQ-------MLAVWQTADGIDVYESGWTFDHFY
MUL_5034|M.ulcerans_Agy99 ---MRFAFKNSPQNTTWEQ-------MLAVWQTADGIDVYESGWTFDHFY
MAV_0169|M.avium_104 ---MRFAFKTSPQNTTWAQ-------MLAVWQAADDIDVYESGWTFDHFY
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPP-----SLPARASIVSGAVLGADSYWVGDHLN
: : : : : :* :. **:
Mb1886c|M.bovis_AF2122/97 QLPMLGTPD--------------QPMLEAYTALGALATATER--LQLGAL
Rv1855c|M.tuberculosis_H37Rv QLPMLGTPD--------------QPMLEAYTALGALATATER--LQLGAL
Mvan_5695|M.vanbaalenii_PYR-1 --PIFSDPS--------------GPCLEGWVTLTALAQATTR--LRVGVL
Mflv_1117|M.gilvum_PYR-GCK --PIFSDPT--------------GPCLEGWVTLTALAQATTR--LRVGVL
MAB_4496c|M.abscessus_ATCC_199 --PIFSDPT--------------GPCLEGWVTLTALAQATQR--LRVGVL
MSMEG_6454|M.smegmatis_MC2_155 --PIFSDSA--------------GPCLEGWTTLTALAQATER--LRVGVL
TH_4285|M.thermoresistible__bu --PIFSDPT--------------GPCLEGWTTLTALAQATTR--LRVGVL
MMAR_5411|M.marinum_M --PIFSDPT--------------GPCLEGWTTLTALAQATTR--LRLGTL
MUL_5034|M.ulcerans_Agy99 --PIFSDPT--------------GPCLEGWTTLTALAQATTR--LRLGTL
MAV_0169|M.avium_104 --PIFSDSS--------------GPCLEGWTTLTALAQATKR--LRLGTL
MLBr_00131|M.leprae_Br4923 ALVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVC
. . . * :. * ** .. *::*.
Mb1886c|M.bovis_AF2122/97 VTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHRQLGFEFGTF
Rv1855c|M.tuberculosis_H37Rv VTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHRQLGFEFGTF
Mvan_5695|M.vanbaalenii_PYR-1 VTGIHYRHPAVLANMASALDIVSDGRLELGIGAGWNEEESGAYGIELGSI
Mflv_1117|M.gilvum_PYR-GCK VTGIHYRHPAVLANMASALDIVSGGRLELGIGAGWNEEESGAYGIELGSI
MAB_4496c|M.abscessus_ATCC_199 VTGIHYRHPAVLANMASALDIVSGGRLELGIGAGWNEEESGAYGIELGSI
MSMEG_6454|M.smegmatis_MC2_155 VTGIHYRHPAVLANMAAALDIISNGRLELGIGAGWNEEESGAYGIELGSI
TH_4285|M.thermoresistible__bu VTGIHYRHPAVLANMASALDIISAGRLELGIGAGWNEEESGAYGIELGTL
MMAR_5411|M.marinum_M VTGVHYRHPAVLANMAAALDIISHGRLELGIGAGWNEEESSAYGIELGSV
MUL_5034|M.ulcerans_Agy99 VTGIHYRHPAVLANMAAALDIISHGRLELGIGAGWNEEESGAYGIELGSV
MAV_0169|M.avium_104 VTGIHYRHPAVLANMAAAVDIISGGRLELGIGAGWNEEESGAYGIELGSI
MLBr_00131|M.leprae_Br4923 VTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGERE-GNEPYGVEW---
**. * *:: *: :::.::: *: ****.* * *.*
Mb1886c|M.bovis_AF2122/97 SDRFNRLEEALQILEPMVK--GERPTFFGDWYTTESAMAEPR--YRDRIP
Rv1855c|M.tuberculosis_H37Rv SDRFNRLEEALQILEPMVK--GERPTFFGDWYTTESAMAEPR--YRDRIP
Mvan_5695|M.vanbaalenii_PYR-1 KERFDRFEEACQVLKGLLS--QDTTTFDGKFYQLKDARNEPKGPQRPHPP
Mflv_1117|M.gilvum_PYR-GCK TERFDRFEEACQVLRGLLS--QETTTSDGRFYQLKDARNEPKGPQQPHPP
MAB_4496c|M.abscessus_ATCC_199 KERFDRFEEACEVLTGLLS--RETTNFDGKFYQLKDARNEPKGPQKPHPP
MSMEG_6454|M.smegmatis_MC2_155 KERFDRFEEACEVLKGLLT--QETTTFDGKFYQLKDARNEPKGPQQPHPP
TH_4285|M.thermoresistible__bu KERFDRFEEACQVLISLLS--QETTDFDGAYYRLKSARNEPKGPQQPHPP
MMAR_5411|M.marinum_M KERFDRFEEACAVLTGLLS--QPSTTFDGKYYQLEDARNEPKGPQRPHPP
MUL_5034|M.ulcerans_Agy99 KERFDRFEEACAVLTGLLS--QPSTTFDGKYYQLEDARNEPKGPQRPHSP
MAV_0169|M.avium_104 RERFDRFEEACAVLTSLLS--QETTDFDGKFYQLKGARNEPKGPQRPHPP
MLBr_00131|M.leprae_Br4923 TKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPE
. . *::** : : . :: ..* :
Mb1886c|M.bovis_AF2122/97 ILIGGGGEKKTFAIAARFADHLN-IVA-AVDELPRKMRALAARCDEAGRD
Rv1855c|M.tuberculosis_H37Rv ILIGGGGEKKTFAIAARFADHLN-IVA-AVDELPRKMRALAARCDEAGRD
Mvan_5695|M.vanbaalenii_PYR-1 ICIGGSGEKRTLRITAQYADHWN-FVGGPPEEFARKRDVLARHCADIGRD
Mflv_1117|M.gilvum_PYR-GCK ICIGGNGEKRTLRITAQYADHWN-YVGGTPEEFARKRDVLAAHCADIGRD
MAB_4496c|M.abscessus_ATCC_199 ICIGGSGEKRTLRITARYAQHWN-FVGGPPEEFARKREVLAAHCADIGRD
MSMEG_6454|M.smegmatis_MC2_155 FCIGGSGEKRTLRITAKYADHWN-FVGGTPEEFARKRDVLAAHCADLGRD
TH_4285|M.thermoresistible__bu ICIGGSGEKRTLRITAKYADHWN-FVGGPPEEFARKRDVLAAHCADVGRD
MMAR_5411|M.marinum_M ICIGGSGEKRTLRITARYAQHWN-FAGGTPEEFARKRDVLAAHCADIGRD
MUL_5034|M.ulcerans_Agy99 ICIGGSGEKRTLRITARYAQHWN-FAGGTPEEFARKRDVLAAHCADIGRD
MAV_0169|M.avium_104 ICIGGSGEKRTLRITARYAQHWN-FVGGPPDVFAHKRDVLASHCADIGRD
MLBr_00131|M.leprae_Br4923 IWVAAHG-PRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRD
: :.. * : : :.::*: . . .: . : ***
Mb1886c|M.bovis_AF2122/97 RSTLQTSLLLTVMIDETLSPDAIPAEMSGRVVVGSPAQIADQIQA-KVLD
Rv1855c|M.tuberculosis_H37Rv RSTLQTSLLLTVMIDETLSPDAIPAEMSGRVVVGSPAQIADQIQA-KVLD
Mvan_5695|M.vanbaalenii_PYR-1 PGEISLSAHIRLGADLDYD-----------KVIEEAAALG---------A
Mflv_1117|M.gilvum_PYR-GCK PKEIMLSAHVRLGADLDVD-----------KVIAEAAALG---------D
MAB_4496c|M.abscessus_ATCC_199 PKEITLSAHIRLGADRDYA-----------RVVDEAASLG---------A
MSMEG_6454|M.smegmatis_MC2_155 PKEITLSAHVRLGEDRDYA-----------KVIDEAAALG---------A
TH_4285|M.thermoresistible__bu PREIRLSAHVRLGEDGDCR-----------KVVDEAAALA---------S
MMAR_5411|M.marinum_M PKEITLSAHLGLAPERDFG-----------QVIENAAALA---------A
MUL_5034|M.ulcerans_Agy99 PKEITLSAHRGLAPERDFG-----------QVIENAAALA---------A
MAV_0169|M.avium_104 PKEILLSAHLRLEPDLDYG-----------KVIDDAAALA---------A
MLBr_00131|M.leprae_Br4923 PMSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHP
: : : :: .
Mb1886c|M.bovis_AF2122/97 AGVDGL-IINLAPHGYLPGVITTAAEALRPLLGV----------------
Rv1855c|M.tuberculosis_H37Rv AGVDGL-IINLAPHGYLPGVITTAAEALRPLLGV----------------
Mvan_5695|M.vanbaalenii_PYR-1 EGLELA-IVYLPLP-HDPAVLEPLADKIRASGLLDSKAR-----------
Mflv_1117|M.gilvum_PYR-GCK EGLDLA-IVYLPPP-YDPAVLEPLAEKIRASGLLDSNVDG----------
MAB_4496c|M.abscessus_ATCC_199 EGLDLA-IIYLPPP-YDPAVLEPLAQALRG--------------------
MSMEG_6454|M.smegmatis_MC2_155 EGLDLA-IIYLPPP-YDPAVLEPLAQAIRDSGQLTAA-------------
TH_4285|M.thermoresistible__bu EGLDLA-IVYLPTP-HTPAVLEPLAEAIRDSGLPAR--------------
MMAR_5411|M.marinum_M EGLDLG-IVYIAPP-HDPAVLEPMAEAIRESGLIDG--------------
MUL_5034|M.ulcerans_Agy99 EGLDLG-IVYIAPP-HDPAVLEPMAEAIRESGLIDG--------------
MAV_0169|M.avium_104 EGLDLG-IVYLPPP-HDPAVLEPLAEAIRDSGLLRS--------------
MLBr_00131|M.leprae_Br4923 MGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVA
* : : : .: . * :
Mb1886c|M.bovis_AF2122/97 ------------------------------------------
Rv1855c|M.tuberculosis_H37Rv ------------------------------------------
Mvan_5695|M.vanbaalenii_PYR-1 ------------------------------------------
Mflv_1117|M.gilvum_PYR-GCK ------------------------------------------
MAB_4496c|M.abscessus_ATCC_199 ------------------------------------------
MSMEG_6454|M.smegmatis_MC2_155 ------------------------------------------
TH_4285|M.thermoresistible__bu ------------------------------------------
MMAR_5411|M.marinum_M ------------------------------------------
MUL_5034|M.ulcerans_Agy99 ------------------------------------------
MAV_0169|M.avium_104 ------------------------------------------
MLBr_00131|M.leprae_Br4923 EWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL