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APAPLEVIDKGESTDAHPAPLLFVHGAWHAAWCWDDHFLDFFAGRGYRALALSFRGHGRSATDKPLRSLS ISDYVDDVATVAARLPTPPIVVGHSMGGFVVQKYLEDRDVPAGVLMASAPPRGYLGSGVRWFRRHPWQFV RTSLSGESLAYVSPIEAARERFFSPSTPEAIVAACAARLQEESARSGRDGVTALPRPKRVRAPMLVLGAL DDGMAVTPAEVHATARAYRTEATLFPGMGHNMMLEPGWEAVASHIDSWLISRGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3379 | - | - | 100% (265) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_3146 | - | 1e-10 | 30.99% (213) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_4507 | - | 2e-06 | 27.18% (103) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0189 | - | 3e-07 | 27.37% (274) | lysophospholipase |
| M. tuberculosis H37Rv | Rv0183 | - | 3e-07 | 27.37% (274) | lysophospholipase |
| M. leprae Br4923 | MLBr_02603 | - | 4e-09 | 26.69% (266) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_4551c | - | 4e-07 | 40.00% (90) | lysophospholipase |
| M. marinum M | MMAR_1669 | - | 1e-08 | 28.35% (261) | lysophospholipase |
| M. avium 104 | MAV_3771 | - | 3e-71 | 54.30% (256) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_0460 | - | 3e-08 | 38.26% (115) | alpha/beta hydrolase fold |
| M. thermoresistible (build 8) | TH_3727 | - | 3e-10 | 29.32% (249) | PUTATIVE Chloride peroxidase |
| M. ulcerans Agy99 | MUL_1905 | - | 8e-09 | 28.35% (261) | lysophospholipase |
| M. vanbaalenii PYR-1 | Mvan_3112 | - | 1e-103 | 68.46% (260) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3379|M.gilvum_PYR-GCK -----------------------------------------MAPAPLEVI
Mvan_3112|M.vanbaalenii_PYR-1 ---------------------------------------------MLEVI
MAV_3771|M.avium_104 ---------------------------------------------MLEVI
MMAR_1669|M.marinum_M --------------------------------------------------
MUL_1905|M.ulcerans_Agy99 --------------------------------------------------
Mb0189|M.bovis_AF2122/97 -------------------------------MTTTRTERNFAGIGDVRIV
Rv0183|M.tuberculosis_H37Rv -------------------------------MTTTRTERNFAGIGDVRIV
MLBr_02603|M.leprae_Br4923 -------------------------------MTITRTERNFYGVGGVRIV
MAB_4551c|M.abscessus_ATCC_199 ------------------------------------MQRTFDGADDVRIV
TH_3727|M.thermoresistible__bu -------------------------------------MATITTSDGVEIF
MSMEG_0460|M.smegmatis_MC2_155 MRHADEVSPLFQRQRPTPSDPPEGTPEWFTAALEHRPQHSTIDFEGCRIH
Mflv_3379|M.gilvum_PYR-GCK DKGESTDAHPAPLLFVHGAWHAAWCWDDHFLDFFAGRGYRALALSFRGHG
Mvan_3112|M.vanbaalenii_PYR-1 DKGSVSQSHPVPLLFVHGAWHAAWCWDEHFLDFFAGRGYRALAVSLRGHG
MAV_3771|M.avium_104 EKGSGSAEHPTPLLFVHGGWHAAWCWEN-FLDFFADAGYRAVALSLRGHG
MMAR_1669|M.marinum_M --------MRKHVVLIHGAWSRGRQLAG-ARSAFEHHGYTVHTPTLRHHE
MUL_1905|M.ulcerans_Agy99 --------MRKHVVLIHGAWSRGRQLAG-ARSAFEHHGYTVHTPTLRHHE
Mb0189|M.bovis_AF2122/97 YDVWTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHG
Rv0183|M.tuberculosis_H37Rv YDVWTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHG
MLBr_02603|M.leprae_Br4923 YDVWMPDTRPRAVIILAHGFGEHARRYDHVAHYFAAAGLATYALDLRGHG
MAB_4551c|M.abscessus_ATCC_199 YDTWTPAGTPRAVVVLSHGFGEHARRYDHVARRFNEAGYLVYALDHRGHG
TH_3727|M.thermoresistible__bu YRDWG----SGQPIVFSHGWPLTADDWDPQMLFFLNAGYRVIAHDRRGHG
MSMEG_0460|M.smegmatis_MC2_155 LRTWG--DPENPPLVFVHGGAAHSGWWDHIAPFFTRT-HRVIAPDVSGHG
:.. . : . : *
Mflv_3379|M.gilvum_PYR-GCK RSATD--KPLRSLSISDYVDDVATVAARLP-----TPPIVVGHSMGGFVV
Mvan_3112|M.vanbaalenii_PYR-1 GSPAD--KKLRDLSFEDFVADITTAADALP-----TRPVIIGHSMGGVLV
MAV_3771|M.avium_104 ASPTS--KPLHRVSIADYLDDVAAVAGELG-----GAPILIGHSLGGFVI
MMAR_1669|M.marinum_M LPLPDGAARIATLSLRDYADDLVELVASLD-----SAPLLVGHSLGGLLV
MUL_1905|M.ulcerans_Agy99 LPLPDGAARIATLSLRDYADDLVELVASLN-----SAPLLVGHSLGGLLV
Mb0189|M.bovis_AF2122/97 RSGGK---RVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIV
Rv0183|M.tuberculosis_H37Rv RSGGK---RVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIV
MLBr_02603|M.leprae_Br4923 RSAGK---RVLVRDLSEYNADFDILVGIATRDHPGLKRIVAGHSMGGAIV
MAB_4551c|M.abscessus_ATCC_199 RSGGK---RVYLRDISEYTDDFGTLVDIAAREHPDLKRIVLGHSMGGGIV
TH_3727|M.thermoresistible__bu RSSPVP----DGHDMDHYADDLAALVEHLG----LRDAVHVGHSTGGGVV
MSMEG_0460|M.smegmatis_MC2_155 DSGTR-----SHYSLTKWAREVLAVAAAEG---PAARPTIVGHSMGGWVT
. .: .: :. . *** ** :
Mflv_3379|M.gilvum_PYR-GCK QKYLEDR---DVPAGVLMASAPPRGYLGSGVR------WFRRHP-WQFVR
Mvan_3112|M.vanbaalenii_PYR-1 QRYLETR---DAPAGVLMASMPPQGSLKSGLR------WIRSHP-WHFAK
MAV_3771|M.avium_104 QRYLETH---RVPAAVLVGSVPPQGVLRLALR------VWRRRP-SMTME
MMAR_1669|M.marinum_M Q-LVAAR---TRHIGVVAACPSPVGPVGLNRTTAGLSMRHALRP-RPWTK
MUL_1905|M.ulcerans_Agy99 Q-LVAAR---TRHIGVVAACPSPVGPVGLNRTTAGLSMRHALRP-RPWTK
Mb0189|M.bovis_AF2122/97 FAYGVER---PDNYDLMVLSAPAVAAQDLVSP-------VVAVA-AKLLG
Rv0183|M.tuberculosis_H37Rv FAYGVER---PDNYDLMVLSAPAVAAQDLVSP-------VVAVA-AKLLG
MLBr_02603|M.leprae_Br4923 FAYGVER---PDNYDLMVLSGPAVAAQDMVSP-------LRAVV-GKGLG
MAB_4551c|M.abscessus_ATCC_199 FAYGVDH---QDRYDLMVLSGPAIAAQVGLPY-------VLTLV-APVVG
TH_3727|M.thermoresistible__bu VRYLARHGEERTAKAVLIAAVPPLMVRTDANPG-----GLPKSV-FDDFQ
MSMEG_0460|M.smegmatis_MC2_155 ATAAMKYG--ADIDSILIIDSPLRERAPEEGRLRNRRSDHPGYPSREEIL
:: .
Mflv_3379|M.gilvum_PYR-GCK TSLSGESLAYVSPIEAARERFFSP---STPEAIVAACAARLQEESARSGR
Mvan_3112|M.vanbaalenii_PYR-1 LTATGRSLPYVSTPELARERFFSP---ATPESVVRHYAARLQEESARMGL
MAV_3771|M.avium_104 AWNDPTLLKFLATPALAREYLFCA---ATPEAIVESCRQRAGAESVRAAM
MMAR_1669|M.marinum_M PVAPPSWPRFRTGIAGAQSAGAAR---EMFEDLVCESGRVLFFELALPWL
MUL_1905|M.ulcerans_Agy99 PVAPPSWPRFRTGIAGAQSAGAAR---EMFDDLVCESGRVLFFELALPWL
Mb0189|M.bovis_AF2122/97 VVVPGLPVQELDFTAISRDPEVVQ---AYNTDPLVHHG-RVPAGIGRALL
Rv0183|M.tuberculosis_H37Rv VVVPGLPVQELDFTAISRDPEVVQ---AYNTDPLVHHG-RVPAGIGRALL
MLBr_02603|M.leprae_Br4923 LVAPGLPVHQLEVDAISRNRAVVA---AYKDDPLVYHG-KVPAGVGRVML
MAB_4551c|M.abscessus_ATCC_199 RLAPGLPVQKLDVNAISHDPAIIA---AYHADPLVHHG-RVPAGIGRALL
TH_3727|M.thermoresistible__bu AQLAANRSEFYRALASGPFYGFNRDGVEPSEALIANWWRQGMMGDAKAHY
MSMEG_0460|M.smegmatis_MC2_155 ARFRAVPAQDVTLPFIDRHIASESVR-QTDTGWVWKFDPAIFSGSLQGQT
:
Mflv_3379|M.gilvum_PYR-GCK ------DGVTALPRPKRVRAPMLVLGALDDGM-AVTPAEVHATARAYR-T
Mvan_3112|M.vanbaalenii_PYR-1 ------DGLVKLPHPSRVRTPLLVLGAADDG--AVTQDEVRATADAYG-T
MAV_3771|M.avium_104 T-----DPMLRRVRTRRVSTPILVLGATHDG--FVSAADVRATARAYR-T
MMAR_1669|M.marinum_M D-----RSKVARVDYPAVTGPVLVLGGEYDR--IVGSTIARQTAGRYRNG
MUL_1905|M.ulcerans_Agy99 D-----RSKVARVDYPAVTGPVLVLGGEYDR--IVGSAIARQTAGRYRNG
Mb0189|M.bovis_AF2122/97 Q-----VGETMPRRAPALTAPLLVLHGTDDRLIPIEGSRRLVECVGSADV
Rv0183|M.tuberculosis_H37Rv Q-----VGETMPRRAPALTAPLLVLHGTDDRLIPIEGSRRLVECVGSADV
MLBr_02603|M.leprae_Br4923 Q-----VGETMTRRAPVLTTPLLVVHGSEDRLVLVDGSHRLVECVGSTDV
MAB_4551c|M.abscessus_ATCC_199 G-----VGKTMRQRAAGLKRPVLTMHGSDDRLTAPEGSRWLSESA--PDA
TH_3727|M.thermoresistible__bu DGIVAFSQTDFTEDLTKITVPVLVMHGDDDQVVPYANSG-PLTAELLRNA
MSMEG_0460|M.smegmatis_MC2_155 P----AEQEILENTFAQIPCRVGYLRCENGLVPPDMAEQIRSTLQLRGPF
: : : .
Mflv_3379|M.gilvum_PYR-GCK EATLFPGMGHNMMLEPGWEAVASHIDSWLISRGL----
Mvan_3112|M.vanbaalenii_PYR-1 EAHIFPGMGHNMMLEAGWEDVADRIDVWLRSRRL----
MAV_3771|M.avium_104 DPEFFD-MGHNMMLEPGWVAVAERIRDWLQAPTAARHR
MMAR_1669|M.marinum_M TFVEIPGSDHLVFSARVLPATMARISEWIAHNQLFATA
MUL_1905|M.ulcerans_Agy99 TFVEIPGSDHLVFSARVLPATMARISEWIAHNHLFATA
Mb0189|M.bovis_AF2122/97 QLKEYPGLYHEVFNEPERNQVLDDVVAWLTERL-----
Rv0183|M.tuberculosis_H37Rv QLKEYPGLYHEVFNEPERNQVLDDVVAWLTERL-----
MLBr_02603|M.leprae_Br4923 ELKVYPGLYHEVFNEPERDQVLEDVVCWILKRL-----
MAB_4551c|M.abscessus_ATCC_199 TLKIWNGLYHEIFNEFEKELVLDEVVGWIDARL-----
TH_3727|M.thermoresistible__bu KLKTYQGFPHGMMTTHA-EVVNADILEFLRS-------
MSMEG_0460|M.smegmatis_MC2_155 VELALAGHHPMLDQPLPLVATIRTLLEFWSIT------
: . : :