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MLEVIEKGSGSAEHPTPLLFVHGGWHAAWCWENFLDFFADAGYRAVALSLRGHGASPTSKPLHRVSIADY LDDVAAVAGELGGAPILIGHSLGGFVIQRYLETHRVPAAVLVGSVPPQGVLRLALRVWRRRPSMTMEAWN DPTLLKFLATPALAREYLFCAATPEAIVESCRQRAGAESVRAAMTDPMLRRVRTRRVSTPILVLGATHDG FVSAADVRATARAYRTDPEFFDMGHNMMLEPGWVAVAERIRDWLQAPTAARHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3771 | - | - | 100% (263) | hydrolase, alpha/beta fold family protein, putative |
| M. avium 104 | MAV_2604 | - | 6e-11 | 32.39% (176) | hydrolase, alpha/beta fold family protein, putative |
| M. avium 104 | MAV_0093 | - | 5e-10 | 28.57% (182) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3502c | bpoA | 1e-08 | 34.31% (102) | peroxidase BpoA |
| M. gilvum PYR-GCK | Mflv_3379 | - | 3e-71 | 54.30% (256) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3473c | bpoA | 1e-08 | 34.31% (102) | peroxidase BpoA |
| M. leprae Br4923 | MLBr_02603 | - | 1e-05 | 31.82% (88) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_3934c | - | 2e-07 | 33.33% (102) | alpha/beta fold hydrolase |
| M. marinum M | MMAR_1669 | - | 2e-10 | 26.19% (252) | lysophospholipase |
| M. smegmatis MC2 155 | MSMEG_5209 | - | 2e-09 | 37.84% (111) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_3727 | - | 1e-13 | 38.33% (120) | PUTATIVE Chloride peroxidase |
| M. ulcerans Agy99 | MUL_1905 | - | 5e-11 | 26.59% (252) | lysophospholipase |
| M. vanbaalenii PYR-1 | Mvan_2148 | - | 7e-76 | 53.58% (265) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1669|M.marinum_M ----------------------------------------MRKHVVLIHG
MUL_1905|M.ulcerans_Agy99 ----------------------------------------MRKHVVLIHG
Mb3502c|M.bovis_AF2122/97 --------------------------------------------MVFLHG
Rv3473c|M.tuberculosis_H37Rv --------------------------------------------MVFLHG
MSMEG_5209|M.smegmatis_MC2_155 MSTAQTESQTVAFRGVDDLTLVGDEWNKGAERAA------DRPTVLLLHG
Mflv_3379|M.gilvum_PYR-GCK -----------------MAPAPLEVIDKGESTDA------HPAPLLFVHG
Mvan_2148|M.vanbaalenii_PYR-1 ---------------------MLEVIDKGACSES------HPVPLLFVHG
MAV_3771|M.avium_104 ---------------------MLEVIEKGSGSAE------HPTPLLFVHG
TH_3727|M.thermoresistible__bu ----------------MATITTSDGVEIFYRDWG------SGQPIVFSHG
MAB_3934c|M.abscessus_ATCC_199 -----------------MPLANINGIQISYDDRGPLALGASGDPVVFISG
MLBr_02603|M.leprae_Br4923 ------------MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHG
::: *
MMAR_1669|M.marinum_M AWSRGRQLAG-ARSAFEHHGYTVHTPTLRHHELPLPDGAARIATLSLRDY
MUL_1905|M.ulcerans_Agy99 AWSRGRQLAG-ARSAFEHHGYTVHTPTLRHHELPLPDGAARIATLSLRDY
Mb3502c|M.bovis_AF2122/97 GGQTRRSWGR-AAAAVAERGWQAVTIDLRGHGE---SDWSSEGDYRLVSF
Rv3473c|M.tuberculosis_H37Rv GGQTRRSWGR-AAAAVAERGWQAVTIDLRGHGE---SDWSSEGDYRLVSF
MSMEG_5209|M.smegmatis_MC2_155 GGQNRYSWKN-TGQILADQGFHVIALDARGHGD---SDRSPSANYSVDAM
Mflv_3379|M.gilvum_PYR-GCK AWHAAWCWDDHFLDFFAGRGYRALALSFRGHGR--SATDKPLRSLSISDY
Mvan_2148|M.vanbaalenii_PYR-1 AWHAAWCWDEHFLDFFADKGFRALAVSLRGHGN--SPSPKPLRTCSLADY
MAV_3771|M.avium_104 GWHAAWCWEN-FLDFFADAGYRAVALSLRGHGA--SPTSKPLHRVSIADY
TH_3727|M.thermoresistible__bu WPLTADDWDP-QMLFFLNAGYRVIAHDRRGHGR----SSPVPDGHDMDHY
MAB_3934c|M.abscessus_ATCC_199 RGGAGRSWHLHQVPAFRAAGYRTITFNNRGIPP----TTESADGFTLQDM
MLBr_02603|M.leprae_Br4923 FGEHARRYDH-VAHYFAAAGLATYALDLRGHGR---SAGKRVLVRDLSEY
. * . : * :
MMAR_1669|M.marinum_M ADDLVELV----ASLDS-APLLVGHSLGGLLVQLVAARTRHIGVVAACPS
MUL_1905|M.ulcerans_Agy99 ADDLVELV----ASLNS-APLLVGHSLGGLLVQLVAARTRHIGVVAACPS
Mb3502c|M.bovis_AF2122/97 AGDIQEVL----RNLPG-QPALVGASLGGFAAMLLAGELSPGIASAVVLV
Rv3473c|M.tuberculosis_H37Rv AGDIQEVL----RNLPG-QPALVGASLGGFAAMLLAGELSPGIASAVVLV
MSMEG_5209|M.smegmatis_MC2_155 CGDVLAVL----YQISR-PVALIGASMGGLTGLLAAHEAGPERVTQLVLV
Mflv_3379|M.gilvum_PYR-GCK VDDVATVA----ARLPT-PPIVVGHSMGGFVVQKYLEDRD---VPAGVLM
Mvan_2148|M.vanbaalenii_PYR-1 LDDVDSVV----DTLPT-TPVLIGHSMGGFIVQKYLEAHQ---APAGVLI
MAV_3771|M.avium_104 LDDVAAVA----GELGG-APILIGHSLGGFVIQRYLETHR---VPAAVLV
TH_3727|M.thermoresistible__bu ADDLAALV----EHLGLRDAVHVGHSTGGGVVVRYLARHGEERTAKAVLI
MAB_3934c|M.abscessus_ATCC_199 VDDTAALI----EQLGAAPARLVGFSMGALIAQELTLTRPELVTAAVFMG
MLBr_02603|M.leprae_Br4923 NADFDILVGIATRDHPGLKRIVAGHSMGGAIVFAYGVERP---DNYDLMV
* : * * *.
MMAR_1669|M.marinum_M PVGP----VGLNRTTAGLSMRHA-----LRPRPWTKPVAPPSWPRFRTG-
MUL_1905|M.ulcerans_Agy99 PVGP----VGLNRTTAGLSMRHA-----LRPRPWTKPVAPPSWPRFRTG-
Mb3502c|M.bovis_AF2122/97 DIVPNMDLAGASRIHAFMAERVESGFGSLDEVADVIANYNPHRPRPSDPD
Rv3473c|M.tuberculosis_H37Rv DIVPNMDLAGASRIHAFMAERVESGFGSLDEVADVIANYNPHRPRPSDPD
MSMEG_5209|M.smegmatis_MC2_155 DVVPNFEKSGSARIRDFMASNVD-GFDTLEEAADAVAAYLPHRRRPRNPE
Mflv_3379|M.gilvum_PYR-GCK ASAPP---RGYLGSGVRWFRRHP----WQFVRTSLSGESLAYVSPIEAAR
Mvan_2148|M.vanbaalenii_PYR-1 ASAPQ---RGSFAFTMRLTRRHP----WLTTKGLITGNALLPVGTPELAR
MAV_3771|M.avium_104 GSVPP---QGVLRLALRVWRRRP----SMTMEAWNDPTLLKFLATPALAR
TH_3727|M.thermoresistible__bu AAVPPLMVRTDANPGGLPKSVFD---DFQAQLAANRSEFYRALASGPFYG
MAB_3934c|M.abscessus_ATCC_199 TRGREDATRSFFRKAELELSASG-----VEVPAAYQAAMRLLLNFSPKTL
MLBr_02603|M.leprae_Br4923 LSGPA---VAAQDMVSPLRAVVG------KGLGLVAPGLPVHQLEVDAIS
MMAR_1669|M.marinum_M --IAGAQSAGAAREMFEDLVCESGRVLFFELALPWLDRSKVARVDYPAVT
MUL_1905|M.ulcerans_Agy99 --IAGAQSAGAAREMFDDLVCESGRVLFFELALPWLDRSKVARVDYPAVT
Mb3502c|M.bovis_AF2122/97 GLVANLRRRGDRWYWHWDPQFIGGIAAFPPVEVTDVDRMNAAVATILRDE
Rv3473c|M.tuberculosis_H37Rv GLVANLRRRGDRWYWHWDPQFIGGIAAFPPVEVTDVDRMNAAVATILRDE
MSMEG_5209|M.smegmatis_MC2_155 GLKKNLRLRDGRWYWHWDPAFLGKPHDDP---FVRVERLEQAAVNLT---
Mflv_3379|M.gilvum_PYR-GCK ERFFSPSTPEAIVAACAARLQEESARSGR-DGVTALPRPKRVR-------
Mvan_2148|M.vanbaalenii_PYR-1 ESFFSSQTPESDVVRYAARLNGESQRVAI-DTIWMLPRPKRVT-------
MAV_3771|M.avium_104 EYLFCAATPEAIVESCRQRAGAESVRAAMTDPMLRRVRTRRVS-------
TH_3727|M.thermoresistible__bu FNRDGVEPSEALIANWWRQGMMGDAKAHYDGIVAFSQTDFTEDLTKIT--
MAB_3934c|M.abscessus_ATCC_199 NNDAAIKDWIDMFTLWPEPASGGIDHQRSAIPAPDRPGAYADIK------
MLBr_02603|M.leprae_Br4923 RNRAVVAAYKDDPLVYHGKVPAGVGRVMLQVGETMTRRAPVLT-------
MMAR_1669|M.marinum_M GPVLVLGGEYDRIVGSTIARQTAGRYRNG--TFVEIPGSDHLVFSARVLP
MUL_1905|M.ulcerans_Agy99 GPVLVLGGEYDRIVGSAIARQTAGRYRNG--TFVEIPGSDHLVFSARVLP
Mb3502c|M.bovis_AF2122/97 VPVLLVRGQVSDIVRQESADQFLSRFPQV--EFTDVRGAGHMVAGDRND-
Rv3473c|M.tuberculosis_H37Rv VPVLLVRGQVSDIVRQESADQFLSRFPQV--EFTDVRGAGHMVAGDRND-
MSMEG_5209|M.smegmatis_MC2_155 VPILLIRGKLSDVVSPEGVAEFLEKVPAA--EFVELSDAGHTAAGDDND-
Mflv_3379|M.gilvum_PYR-GCK APMLVLGALDDGMAVTPAEVHATARAYRT--EATLFPGMGHNMMLEPGWE
Mvan_2148|M.vanbaalenii_PYR-1 TPLLILGAECD-RSILSKEVRTTANAYRT--EAEIFPDMGHDMMLEPGWA
MAV_3771|M.avium_104 TPILVLGATHD-GFVSAADVRATARAYRT--DPEFF-DMGHNMMLEPGWV
TH_3727|M.thermoresistible__bu VPVLVMHGDDDQVVPYANSGPLTAELLRN--AKLKTYQGFPHGMMTTHAE
MAB_3934c|M.abscessus_ATCC_199 VPSLVIGFTDDMTLPPYLGKEVADAIPGG--QYVEISDAGHLGFIERPD-
MLBr_02603|M.leprae_Br4923 TPLLVVHGSEDRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERD
* *:: .
MMAR_1669|M.marinum_M ATMARISEWIAHNQLFATA------------
MUL_1905|M.ulcerans_Agy99 ATMARISEWIAHNHLFATA------------
Mb3502c|M.bovis_AF2122/97 AFAGAVLDFLARHVGVR--------------
Rv3473c|M.tuberculosis_H37Rv AFAGAVLDFLARHVGVR--------------
MSMEG_5209|M.smegmatis_MC2_155 AFTQVVVEFVNR-------------------
Mflv_3379|M.gilvum_PYR-GCK AVASHIDSWLISRGL----------------
Mvan_2148|M.vanbaalenii_PYR-1 AVAERIHTWLEMRDLRPHRGEPDQQETTPTG
MAV_3771|M.avium_104 AVAERIRDWLQAPTAARHR------------
TH_3727|M.thermoresistible__bu VVNADILEFLRS-------------------
MAB_3934c|M.abscessus_ATCC_199 EVNRVILEFFASTAQTV--------------
MLBr_02603|M.leprae_Br4923 QVLEDVVCWILKRL-----------------
: :.