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MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGR SGGKRVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQ DLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRR APALTAPLLVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTERL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0189 | - | - | 100% (279) | lysophospholipase |
| M. bovis AF2122 / 97 | Mb3196c | hpx | 2e-10 | 28.73% (275) | non-Heme haloperoxidase Hpx |
| M. bovis AF2122 / 97 | Mb2734 | - | 2e-06 | 21.83% (252) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0518 | - | 1e-110 | 67.75% (276) | acylglycerol lipase |
| M. tuberculosis H37Rv | Rv0183 | - | 1e-161 | 100.00% (279) | lysophospholipase |
| M. leprae Br4923 | MLBr_02603 | - | 1e-123 | 74.91% (279) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_4551c | - | 2e-98 | 64.84% (273) | lysophospholipase |
| M. marinum M | MMAR_0427 | - | 1e-143 | 89.61% (279) | lysophospholipase |
| M. avium 104 | MAV_4997 | - | 1e-135 | 83.27% (275) | lysophospholipase |
| M. smegmatis MC2 155 | MSMEG_0220 | - | 1e-108 | 67.03% (279) | monoglyceride lipase |
| M. thermoresistible (build 8) | TH_0684 | hpx | 1e-11 | 27.54% (276) | POSSIBLE NON-HEME HALOPEROXIDASE HPX |
| M. ulcerans Agy99 | MUL_1077 | - | 1e-142 | 88.89% (279) | lysophospholipase |
| M. vanbaalenii PYR-1 | Mvan_0150 | - | 1e-114 | 69.53% (279) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0518|M.gilvum_PYR-GCK ----MTHSERSFDGLGGVRIVYDVWTPESDSRGVVVLAHGYAEHARRYDH
Mvan_0150|M.vanbaalenii_PYR-1 --MAVTRTERSFDGVGGVRIVYDVWTPETPPRGIVVLAHGYAEHARRYDH
MSMEG_0220|M.smegmatis_MC2_155 -MVSSTRSEHSFAGVGGVRIVYDVWTPDTDPRGVVVLAHGYAEHAGRYHH
Mb0189|M.bovis_AF2122/97 --MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDH
Rv0183|M.tuberculosis_H37Rv --MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDH
MMAR_0427|M.marinum_M --MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDH
MUL_1077|M.ulcerans_Agy99 --MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDH
MAV_4997|M.avium_104 --MN--RTERSFDGVGGVRIVYDVWTPEVAPRAVLVLAHGFGEHARRYDH
MLBr_02603|M.leprae_Br4923 --MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHGFGEHARRYDH
MAB_4551c|M.abscessus_ATCC_199 -------MQRTFDGADDVRIVYDTWTPAGTPRAVVVLSHGFGEHARRYDH
TH_0684|M.thermoresistible__bu VEQMPPGRVVSVTAPDGVRLHAEVFGPADAPP--IVLAHGITCAIRVWAH
.. . ..*:: :.: * . ::*:** : *
Mflv_0518|M.gilvum_PYR-GCK VAARFAESGLITYALDHRGHGRSGG-KRVYLRDITEYTGDFHTLVGIARN
Mvan_0150|M.vanbaalenii_PYR-1 VAARFAEAGLGIYALDHRGHGRSGG-KRVYVRDISEYTGDFHSLVRIAAG
MSMEG_0220|M.smegmatis_MC2_155 VAQRFGAAGLLVYALDHRGHGRSGG-KRVHLRDLSEFVEDFRTLVGIAAN
Mb0189|M.bovis_AF2122/97 VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
Rv0183|M.tuberculosis_H37Rv VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
MMAR_0427|M.marinum_M VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
MUL_1077|M.ulcerans_Agy99 VAQRLGAAGLVTYTLDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
MAV_4997|M.avium_104 VARRFGAAGLVTYALDHRGHGRSGG-KRVLVRDIHEYTTDFDTLVGIATR
MLBr_02603|M.leprae_Br4923 VAHYFAAAGLATYALDLRGHGRSAG-KRVLVRDLSEYNADFDILVGIATR
MAB_4551c|M.abscessus_ATCC_199 VARRFNEAGYLVYALDHRGHGRSGG-KRVYLRDISEYTDDFGTLVDIAAR
TH_0684|M.thermoresistible__bu QIAELADD-YRVIAFDHRGHGRSSVPRRRWQYSLDHLASDLDAVLDATLD
: ::* ******. :* .: . *: :: :
Mflv_0518|M.gilvum_PYR-GCK AYPHLKLIVLGHSMGGGVVFTYGVEHPD--------------DYDAMVLS
Mvan_0150|M.vanbaalenii_PYR-1 EHPGRKLVVLGHSMGGGVVFTYGVEHPD--------------DYDAMVLS
MSMEG_0220|M.smegmatis_MC2_155 DHPTLPRIVLGHSMGGGIVFAYGARYPG--------------EYSAMVLS
Mb0189|M.bovis_AF2122/97 EYPGCKRIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
Rv0183|M.tuberculosis_H37Rv EYPGCKRIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MMAR_0427|M.marinum_M DNPGLKCIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MUL_1077|M.ulcerans_Agy99 DNPGLKCIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MAV_4997|M.avium_104 EHHGLKCIVVGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MLBr_02603|M.leprae_Br4923 DHPGLKRIVAGHSMGGAIVFAYGVERPD--------------NYDLMVLS
MAB_4551c|M.abscessus_ATCC_199 EHPDLKRIVLGHSMGGGIVFAYGVDHQD--------------RYDLMVLS
TH_0684|M.thermoresistible__bu --PGERAVIAGHSMGGIAISSWAERYPERVSERAAAVALINTTTGDLLHN
:: ****** : ::. . :: .
Mflv_0518|M.gilvum_PYR-GCK GPAVNAHDSVPAVKLVMAKVLGRIAPGLPVENLPADAVSRDPQVVSDYEN
Mvan_0150|M.vanbaalenii_PYR-1 GPAVDAHSSVSPVMVLLAKVLGRLSPGLPVENLPADAVSRDPQVVAAYEN
MSMEG_0220|M.smegmatis_MC2_155 GPAVNAHDGVSPVLVAVAKVLGKLAPGIPVENLDADAVSRDPEVVAAYKA
Mb0189|M.bovis_AF2122/97 APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
Rv0183|M.tuberculosis_H37Rv APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
MMAR_0427|M.marinum_M APAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
MUL_1077|M.ulcerans_Agy99 APAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
MAV_4997|M.avium_104 GPAVAAQDQVSPLLALAAKVLGVIVPGLPAQELDADAVSRDPEVVAAYRN
MLBr_02603|M.leprae_Br4923 GPAVAAQDMVSPLRAVVGKGLGLVAPGLPVHQLEVDAISRNRAVVAAYKD
MAB_4551c|M.abscessus_ATCC_199 GPAIAAQVGLPYVLTLVAPVVGRLAPGLPVQKLDVNAISHDPAIIAAYHA
TH_0684|M.thermoresistible__bu VQLLPVPDRFAAVRVRTASAVIKTVAGMPARLAAVPSRYVVSMMAVGRDA
: . .. : . : .*:*.. : :
Mflv_0518|M.gilvum_PYR-GCK DPLVH----------HGKLPAGVGRALIAVGETMPARAAAITAPLLVVHG
Mvan_0150|M.vanbaalenii_PYR-1 DPLVH----------HGKLPAGVGRALIGVGETMPARAAAITAPLLIVHG
MSMEG_0220|M.smegmatis_MC2_155 DPMVH----------HGKLPAGIARALIGLGQSMPQRAAALTAPLLVVHG
Mb0189|M.bovis_AF2122/97 DPLVH----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHG
Rv0183|M.tuberculosis_H37Rv DPLVH----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHG
MMAR_0427|M.marinum_M DPQVY----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHG
MUL_1077|M.ulcerans_Agy99 DPQVY----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHG
MAV_4997|M.avium_104 DPLVY----------HGKVPAGVGRALLQVGETMPQRAPALTAPLLVVHG
MLBr_02603|M.leprae_Br4923 DPLVY----------HGKVPAGVGRVMLQVGETMTRRAPVLTTPLLVVHG
MAB_4551c|M.abscessus_ATCC_199 DPLVH----------HGRVPAGIGRALLGVGKTMRQRAAGLKRPVLTMHG
TH_0684|M.thermoresistible__bu DPAITNFVHELFTETPPAARDGWARTLVDAMGPRHIGLHNLTVPTLVIGS
** : * .*.:: . :. * * : .
Mflv_0518|M.gilvum_PYR-GCK DKDRLIPVAGSRQLMECIGSPDAHLKVYPGLYHEVFNEPEKELVLDDVTS
Mvan_0150|M.vanbaalenii_PYR-1 DNDKLIPVEGSRKLVDRVGSADVHLKEYPGLYHEVFNEPEKALVLDDVTS
MSMEG_0220|M.smegmatis_MC2_155 DKDRLIPVAGSRLLVDRVASEDVHLKVYPGLYHEVFNEPEQKLVLDDVTS
Mb0189|M.bovis_AF2122/97 TDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVA
Rv0183|M.tuberculosis_H37Rv TDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVA
MMAR_0427|M.marinum_M TDDRLIPIEGSRRLVGHVGSADVELKEYPGLYHEAFNEPERDQVLDDVVS
MUL_1077|M.ulcerans_Agy99 TDDRLIPIEGSRRLVGHVGSADVELKEYPGPYHEAFNEPERDQVLDDVVS
MAV_4997|M.avium_104 SDDRLIPVAGSRRLVECVGSADVELKVYPGLYHEVFNEPEREQVLDDVVG
MLBr_02603|M.leprae_Br4923 SEDRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERDQVLEDVVC
MAB_4551c|M.abscessus_ATCC_199 SDDRLTAPEGSRWLSESAP--DATLKIWNGLYHEIFNEFEKELVLDEVVG
TH_0684|M.thermoresistible__bu DRDRLLPLVSSRRIAEAAPN-LFDFVELPGGHCAILECPDRVNDHLRALA
*:* .*: : : * : :: :: .
Mflv_0518|M.gilvum_PYR-GCK WIESKL-----
Mvan_0150|M.vanbaalenii_PYR-1 WIESQL-----
MSMEG_0220|M.smegmatis_MC2_155 WIVSHL-----
Mb0189|M.bovis_AF2122/97 WLTERL-----
Rv0183|M.tuberculosis_H37Rv WLTERL-----
MMAR_0427|M.marinum_M WITARL-----
MUL_1077|M.ulcerans_Agy99 WITARL-----
MAV_4997|M.avium_104 WITARL-----
MLBr_02603|M.leprae_Br4923 WILKRL-----
MAB_4551c|M.abscessus_ATCC_199 WIDARL-----
TH_0684|M.thermoresistible__bu AAAADARRATS