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MPERGRSADPRAQRVRNSLRDAAFALAREHPVDTISVGDIAARADVSRQVFYRHFRDRDHAVAAAFGHAF DDALADGAGQDARARILDLFGFAAAHPRLCRNVVPSTVHQHVLVTYRDALYAPCRRIAGQSMEVLDAVSS LPAEAVTRFLVGGLVEVLRSWMEDPDATDLNGRIQAALDTVDALLGIASAQKGSTRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3329 | - | - | 100% (197) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4630 | - | 6e-08 | 28.07% (171) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5054 | - | 6e-07 | 41.67% (60) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 1e-07 | 25.26% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 3e-07 | 26.29% (194) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4330 | - | 2e-06 | 24.55% (167) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5384 | - | 1e-06 | 26.63% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 1e-07 | 25.00% (188) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3572 | - | 1e-51 | 59.46% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2910 | - | 7e-07 | 32.18% (87) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_5004 | - | 4e-06 | 26.53% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3055 | - | 9e-79 | 72.08% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3329|M.gilvum_PYR-GCK -----------------MPERGRSADPRAQRVRNSLRDAAFALAREH--P
Mvan_3055|M.vanbaalenii_PYR-1 -----------------MTERGRSADPRAERVHTRLREAAFAMAHEH--P
MSMEG_3572|M.smegmatis_MC2_155 -----------------MAARTHSADPRAERVRTRLHEAAFALAHER--P
Mb0281c|M.bovis_AF2122/97 ------------MTRSDRPYRGVEAAERLATRRRQLLSAGLDLLGSDQHD
Rv0275c|M.tuberculosis_H37Rv ------------MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHD
MAB_4330|M.abscessus_ATCC_1997 ------------MS-SSRVYGGVEAPDRQAERRNRLLDAGLDLLTSG--P
MAV_3986|M.avium_104 -------------MSSPSRWAGVPLKDRRAERRALLVEAAYRLFGSE--G
MMAR_5384|M.marinum_M -------------------MVRPAQTVRSERTREALRQAAVVRFLAQ--G
MUL_5004|M.ulcerans_Agy99 -------------------MVRPAQTVRSERTREALRQAAVVRFLAQ--G
TH_2910|M.thermoresistible__bu MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARLLDAATSLLTSG--G
* : .*.
Mflv_3329|M.gilvum_PYR-GCK VDTISVGDIAARADVSRQVFYRHFRDRDHAVAAAFGHAFDDALAD-----
Mvan_3055|M.vanbaalenii_PYR-1 VDRITVGDLVGRAKVSRQVFYRHFRDRDDAVASAFSRAFTDATGG-----
MSMEG_3572|M.smegmatis_MC2_155 VDELTVSDIVGRAGVSRQVFYQHFGDRDEAVAAAFATEFTRAIDG-----
Mb0281c|M.bovis_AF2122/97 IAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAV
Rv0275c|M.tuberculosis_H37Rv IAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAV
MAB_4330|M.abscessus_ATCC_1997 APNLTVRGVCKHAGVVARYFYENFTDLDQLSAEVFDRAIGHVATTTQQAV
MAV_3986|M.avium_104 EAAVSVRSVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQLEEVIAAAI
MMAR_5384|M.marinum_M VEETSAEQIAADAGVSLRTFYRHFRSKHDLLFADYTGLHWFRAALDARPV
MUL_5004|M.ulcerans_Agy99 VEETSAEQIAADAGVSLRTFYRHFRSKHDLLFADYTGLHWFRAALDARPV
TH_2910|M.thermoresistible__bu VEAVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERLLPQVTSPPATG-
: : . : :*. * . . :
Mflv_3329|M.gilvum_PYR-GCK -----GAGQDARARILDLFGFAAAHPRLCRNVVPSTVHQHVLVTYRDALY
Mvan_3055|M.vanbaalenii_PYR-1 -----ATGGDARTRILDLFEFAGAHPAMCRNIVPSTVNQHVLATYRDALF
MSMEG_3572|M.smegmatis_MC2_155 -----LRG-DPRARIVRLFDFAGEHRAMYRNVVPSAVTQRVVNAFRDELT
Mb0281c|M.bovis_AF2122/97 TAV--PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESS
Rv0275c|M.tuberculosis_H37Rv TAV--PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESS
MAB_4330|M.abscessus_ATCC_1997 DAA--PLPEKTSAGIANLVRVIEGDPRIGTLMFGNNPANSVIAERRQAAW
MAV_3986|M.avium_104 EQAGDSLRARTRAGIAAVLGFSSADPRRGRVLFTDARTNPVLAARRRATQ
MMAR_5384|M.marinum_M DET---IIDSVQTAIFAFPYDVEAVAKIATLRGGELDPSRIVRHIQEVQA
MUL_5004|M.ulcerans_Agy99 DEA---IIDSVQTAIFAFPYDVEAVAKIATLRGGELDPSRIVRHIQEVQA
TH_2910|M.thermoresistible__bu -----DLRDQLIELVHRQAALIDEAPLHLTALAWLALGPDPNSDARQPLA
: :
Mflv_3329|M.gilvum_PYR-GCK APCRRIAGQS-MEVLDAV--------SSLPAEAVTRFLVGGLVEVLRSWM
Mvan_3055|M.vanbaalenii_PYR-1 EPCQQIAEQG-MAVLDTV--------APLPAEAVTRFLVGGFMEVLRSWM
MSMEG_3572|M.smegmatis_MC2_155 PACAEIAEQG-MTVVAPI--------AGLSPEAVTRFLVGGFVEVLRSWM
Mb0281c|M.bovis_AF2122/97 ALFAMLSGQHAVDTLHAP--------ANDHVKAVAHFAVGGVGQTISAWL
Rv0275c|M.tuberculosis_H37Rv ALFAMLSGQHAVDTLHAP--------ANDHVKAVAHFAVGGVGQTISAWL
MAB_4330|M.abscessus_ATCC_1997 DMFAALSGQHMNKTYQAT--------NDETLRAVSYYTVGGVGHTLAAWV
MAV_3986|M.avium_104 DMLRQGVLSEGWRLNPRS--------DPVAAEVAAAMYTGAMAELAQQWL
MMAR_5384|M.marinum_M DFAEVIAAQLRRRSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWM
MUL_5004|M.ulcerans_Agy99 DFAEVIAAQLLRRSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWM
TH_2910|M.thermoresistible__bu GLSARVIEQYRQPFDELLAG--AAARDELDDFDTTLAIIQLLGPIVFAKL
. .: . :
Mflv_3329|M.gilvum_PYR-GCK EDP---DATDLNGRIQAALDTVDALLGIASAQKGSTRG------------
Mvan_3055|M.vanbaalenii_PYR-1 EDP---HATDLHARVSAALDTVDALLGTSPAQKGPTHG------------
MSMEG_3572|M.smegmatis_MC2_155 EDPDAGDARDLRDRVAAAFDTVNSLLTLNF--------------------
Mb0281c|M.bovis_AF2122/97 AGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVA
Rv0275c|M.tuberculosis_H37Rv AGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVA
MAB_4330|M.abscessus_ATCC_1997 SGQLKLPGTELVRVLTELL-------------------------------
MAV_3986|M.avium_104 AGHLGGDLDAVVDYASKLVLR-----------------------------
MMAR_5384|M.marinum_M LGEDR-SLGELARVCQLALETLRAGLTNTWCPDRPRTVSS----------
MUL_5004|M.ulcerans_Agy99 LGEDR-SLGELARVCQLALETSRAGLTNTWCPDRPRTVSS----------
TH_2910|M.thermoresistible__bu TGMKTLTPADRVRIVDDFLVAHRPPTPETA--------------------
. .
Mflv_3329|M.gilvum_PYR-GCK -------------
Mvan_3055|M.vanbaalenii_PYR-1 -------------
MSMEG_3572|M.smegmatis_MC2_155 -------------
Mb0281c|M.bovis_AF2122/97 GQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv GQPPSSARPARRS
MAB_4330|M.abscessus_ATCC_1997 -------QPVRR-
MAV_3986|M.avium_104 -------------
MMAR_5384|M.marinum_M -------------
MUL_5004|M.ulcerans_Agy99 -------------
TH_2910|M.thermoresistible__bu -------------