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VRPAQTVRSERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRTFYRHFRSKHDLLFADYTGLHWFR AALDARPVDEAIIDSVQTAIFAFPYDVEAVAKIATLRGGELDPSRIVRHIQEVQADFAEVIAAQLLRRSC AAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRSLGELARVCQLALETSRAGLTNTWCPDRPR TVSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_5004 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2933 | - | 9e-27 | 36.73% (196) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_0910 | - | 3e-07 | 49.02% (51) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-87 | 78.16% (206) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 8e-73 | 70.59% (204) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 1e-87 | 78.16% (206) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3837 | - | 5e-07 | 23.33% (180) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_5384 | - | 1e-117 | 98.60% (215) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0197 | - | 2e-90 | 78.60% (215) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6503 | - | 3e-07 | 34.13% (167) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3524 | - | 1e-11 | 31.19% (202) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_5077 | - | 2e-73 | 71.29% (202) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1676|M.gilvum_PYR-GCK -MVRPAQTVR-SERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRT
Mvan_5077|M.vanbaalenii_PYR-1 -MVRPAQTAR-SERTREALRQAAVVRFLAQGVEDTSAEQIAADAGVSLRT
MUL_5004|M.ulcerans_Agy99 -MVRPAQTVR-SERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
MMAR_5384|M.marinum_M -MVRPAQTVR-SERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
Mb3860c|M.bovis_AF2122/97 -MVRPPQTAR-SERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
Rv3830c|M.tuberculosis_H37Rv -MVRPPQTAR-SERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
MAV_0197|M.avium_104 -MVRPAQTAR-SERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRT
TH_3524|M.thermoresistible__bu --------VR-GHRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPRT
MAB_3837|M.abscessus_ATCC_1997 MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRT
MSMEG_6503|M.smegmatis_MC2_155 -MTKP----R-GRGGRERIVAAAAALFEAQGITATTMEQIAAKAPVSKRT
* *: : .* * :* .: ::** * :: **
Mflv_1676|M.gilvum_PYR-GCK FYRHFASKH----DLLFADYDAGLHWFRAALATRSPEDPILDTVQAAIMA
Mvan_5077|M.vanbaalenii_PYR-1 FYRHFASKH----DLLFADYDAGLHWFRSALAARSPEESIFESVQSAIMA
MUL_5004|M.ulcerans_Agy99 FYRHFRSKH----DLLFADY-TGLHWFRAALDARPVDEAIIDSVQTAIFA
MMAR_5384|M.marinum_M FYRHFRSKH----DLLFADY-TGLHWFRAALDARPVDETIIDSVQTAIFA
Mb3860c|M.bovis_AF2122/97 FYRHFRSKH----DLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFS
Rv3830c|M.tuberculosis_H37Rv FYRHFRSKH----DLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFS
MAV_0197|M.avium_104 FYRHFRSKH----DLLFADY-TGLHWFRAALDARPADEPIIDSVQAAIFS
TH_3524|M.thermoresistible__bu FFRHFAAKE----DILFHGYADRLAEATRRFRAARSG-SLWKALAEASEA
MAB_3837|M.abscessus_ATCC_1997 VFRYYSSKN----AIVWGDFDSHLGVMRALLDETADTVDTSTALRQAVLT
MSMEG_6503|M.smegmatis_MC2_155 LYAHFPTKDDLVVEFLQYVYRSGLTVESALYDADVPARERILAMFTVPTR
.: :: :*. :: : * :: .
Mflv_1676|M.gilvum_PYR-GCK APYDDWAVTKIAAMRSQELDAGRIVR-HIRQVEADFADAIDEHLARADGA
Mvan_5077|M.vanbaalenii_PYR-1 SPYEDWAVTKIAAMRAKELDTGRIVR-HIRQVEADFAEAVEQHMAAAGAA
MUL_5004|M.ulcerans_Agy99 FPYDVEAVAKIATLRGGELDPSRIVR-HIQEVQADFAEVIAAQLLRRSCA
MMAR_5384|M.marinum_M FPYDVEAVAKIATLRGGELDPSRIVR-HIQEVQADFAEVIAAQLRRRSCA
Mb3860c|M.bovis_AF2122/97 FPYDVDAVTKIASLRRGELEPSRIVR-HMREVEADFADAIQAQLRRRNCD
Rv3830c|M.tuberculosis_H37Rv FPYDVDAVTKIASLRRGELEPSRIVR-HMREVEADFADAIQAQLRRRNCD
MAV_0197|M.avium_104 FPYDVDAVTKIAALRHEELDPGRIVR-HIRDVQADFAEAIAAQLQRRGRG
TH_3524|M.thermoresistible__bu VATAIAENPGIFLVRARMYGELPALRATMLRINDDWIDQMTTEVARWLGS
MAB_3837|M.abscessus_ATCC_1997 FNDFPVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFVARRSGT
MSMEG_6503|M.smegmatis_MC2_155 GDGPVRG-CPFVAAATEFPDPDSPAHAYTRERKQAFTLRIAELLTELGAD
: : : :
Mflv_1676|M.gilvum_PYR-GCK SPGTD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDSS-----LPELD
Mvan_5077|M.vanbaalenii_PYR-1 APGTD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDRS-----LPELD
MUL_5004|M.ulcerans_Agy99 AAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRS-----LGELA
MMAR_5384|M.marinum_M AAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRS-----LGELA
Mb3860c|M.bovis_AF2122/97 IAGAP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRS-----LGELA
Rv3830c|M.tuberculosis_H37Rv IAGAP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRS-----LGELA
MAV_0197|M.avium_104 -AGAPTA--DQRVRAAVTARCIAAAVFGAMEVWMVGDERS-----LGELA
TH_3524|M.thermoresistible__bu DAAVD-------VRPRLAATVINGANRTAIDLWVSADGKGDLVELMADAV
MAB_3837|M.abscessus_ATCC_1997 DPGSL--------LPQTVAWTLLGVALAAYEQWLADESSK--------LT
MSMEG_6503|M.smegmatis_MC2_155 DPHGL-----------AEQLAILTDGVASRSMVFNDARRG----------
. : : . .
Mflv_1676|M.gilvum_PYR-GCK RLCRHALDLLRTGIADPA----------
Mvan_5077|M.vanbaalenii_PYR-1 RLCRQALTLLRSGIEDPVG---------
MUL_5004|M.ulcerans_Agy99 RVCQLALETSRAGLTNTWCPDRPRTVSS
MMAR_5384|M.marinum_M RVCQLALETLRAGLTNTWCPDRPRTVSS
Mb3860c|M.bovis_AF2122/97 RVCHVALESLRVGISDTWTTLT---VSS
Rv3830c|M.tuberculosis_H37Rv RVCHVALESLRVGISDTWTTLT---VSS
MAV_0197|M.avium_104 RLCHAALESLRAGITDSWSTATAPQVSS
TH_3524|M.thermoresistible__bu RLVRPTLDRIERESRTVANPVRRRDVV-
MAB_3837|M.abscessus_ATCC_1997 TLLGKGFDAAEVGLRALR----------
MSMEG_6503|M.smegmatis_MC2_155 DVGRAAAEALLTAAGL------------
: