For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2910 (-)

annotation: transcriptional regulator, TetR family
coordinates: 4453711 - 4454373
length: 221

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2910--100% (221)transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_0409-6e-3946.70% (197) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0084-8e-0930.18% (169) putative transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1581-6e-0935.11% (94) regulatory protein
M. gilvum PYR-GCKMflv_4579-3e-6663.27% (196) TetR family transcriptional regulator
M. tuberculosis H37RvRv1556-6e-0935.11% (94) regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0579c-3e-0941.89% (74) TetR family transcriptional regulator
M. marinum MMMAR_4834-3e-6865.99% (197) TetR family transcriptional regulator
M. avium 104MAV_3805-2e-5755.67% (203) putative transcriptional regulator
M. smegmatis MC2 155MSMEG_1430-8e-4551.76% (199) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_1934-2e-1127.64% (199) regulatory protein
M. vanbaalenii PYR-1Mvan_0323-4e-6663.27% (196) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1581|M.bovis_AF2122/97            -------------MVGAVTQIA-----------DRPTDPSPWSPRE-TEL
Rv1556|M.tuberculosis_H37Rv         -------------MVGAVTQIA-----------DRPTDPSPWSPRE-TEL
MUL_1934|M.ulcerans_Agy99           --------------MGAMTQTA-----------DRSAQVSPWSPRE-AEL
Mflv_4579|M.gilvum_PYR-GCK          --------------MSDSQSVP---------VPDD--DVDPRRIRSRTRL
Mvan_0323|M.vanbaalenii_PYR-1       --------------MSDSQSVP---------VPDD--DVDPRRIRSRTRL
MAV_3805|M.avium_104                --------------MG-TQPAE---------TPDDEDDVDPRRTRSRTRL
MMAR_4834|M.marinum_M               -------------MERDTLEFP---------VDDD-DDVDPRRLRSRTRL
TH_2910|M.thermoresistible__bu      --------------MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARL
MSMEG_1430|M.smegmatis_MC2_155      --------------MTPGS-------------------NDPRPARSRARL
MAB_0579c|M.abscessus_ATCC_199      MATPRTSSASEAAQSGDGDTDATSQPAAVSALSDDDLGSSAQRERR-KRI
                                                                           ..   *   .:

Mb1581|M.bovis_AF2122/97            LAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG
Rv1556|M.tuberculosis_H37Rv         LAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG
MUL_1934|M.ulcerans_Agy99           LAVTLQLLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG
Mflv_4579|M.gilvum_PYR-GCK          LDAAATLLSTGGVEAVTIDAVTKASKVARTTLYRHFHSSSHLLAATFERL
Mvan_0323|M.vanbaalenii_PYR-1       LDAAATLLSTGGVEAVTIDAVTKASKVARTTLYRHFHSSSHLLAATFERL
MAV_3805|M.avium_104                LDAAANLLKTGGIEAVTIDAVTKASKVARTTLYRHFNSSSQLLAATFERL
MMAR_4834|M.marinum_M               LDAATKLLSAGGIEAVTIDAVTKASKVARTTLYRHFSSSTQLLAATFERL
TH_2910|M.thermoresistible__bu      LDAATSLLTSGGVEAVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERL
MSMEG_1430|M.smegmatis_MC2_155      LEAATVLLRSGGPSAVTVDAVTRAANVARATLYRHFPSGNDLLAAAFRQL
MAB_0579c|M.abscessus_ATCC_199      LDATLAIASKGGYEAVQMRTVAERADVAVGTLYRYFPSKVHLLVSALERE
                                    * .:  :    * . : : :*:  : .:  *:** : *  .*:  :: . 

Mb1581|M.bovis_AF2122/97            IRQVAVP-----PNTGNLRDDLLRLG---ELICREVGQHASTIRAVLVEV
Rv1556|M.tuberculosis_H37Rv         IRQVAVP-----PNTGNLRDDLLRLG---ELICREVGQHASTIRAVLVEV
MUL_1934|M.ulcerans_Agy99           VRQVAVA-----PNTGSLRDDLVKIG---EGICGQAHQQASTIRAVLVEV
Mflv_4579|M.gilvum_PYR-GCK          LPQVTTPA----PTSGPLREQLIELLSRQAALFNDAPLHVTTLAWLSLGP
Mvan_0323|M.vanbaalenii_PYR-1       LPQVTTPA----PTSGPLREQLIELLSRQAALFNDAPLHVTTLAWLSLGP
MAV_3805|M.avium_104                LPQVIPPA----PTSGTLRERLIELLSRQADLFAEAPVQVTTLAWAALGP
MMAR_4834|M.marinum_M               LPQVHPP-----PATGSMRDQLIELLSRQATLFQEAPLHVTTLAWVALGP
TH_2910|M.thermoresistible__bu      LPQVTSP-----PATGDLRDQLIELVHRQAALIDEAPLHLTALAWLALGP
MSMEG_1430|M.smegmatis_MC2_155      IPAAPTP-----PQEGTLRDRLIALVSAQAELIAEAPVTVTAMSWLALGA
MAB_0579c|M.abscessus_ATCC_199      FEQIDAKSDRNAVSGGTPYERLHAAITRLNRNMQRNPLLTEAMTRALVFA
                                    .              *   : *                   ::    :  

Mb1581|M.bovis_AF2122/97            SRN----PALNDV----LQHQFVDHRKALIQYILQQAVDRGEISSAAISD
Rv1556|M.tuberculosis_H37Rv         SRN----PALNDV----LQHQFVDHRKALIQYILQQAVDRGEISSAAISD
MUL_1934|M.ulcerans_Agy99           SRH----PALSDA----LQRQFVDQRKALIQQVLQQAVDRGEITQAAITD
Mflv_4579|M.gilvum_PYR-GCK          TGS-NNEADDRHT-SVALRARVVDQYRQPFDAILTSPKAQAELDDFDREL
Mvan_0323|M.vanbaalenii_PYR-1       TGS-NNEADDRHT-SGALRARVVDQYRQPFDAILTSPKAQAELDDFDREL
MAV_3805|M.avium_104                AET-HEPNTVQHAGAGTLRMRVIEQYRRPFDEILYSPESVDQLGELDIEL
MMAR_4834|M.marinum_M               TPDGTQETQDRHA----LRARIIDQYRQPFVALLQSPEARADLDDFDMEL
TH_2910|M.thermoresistible__bu      DPN----SDARQP-LAGLSARVIEQYRQPFDELLAGAAARDELDDFDTTL
MSMEG_1430|M.smegmatis_MC2_155      DMEHLPLSASPEV--LSLRERVAEQYAAPFEAIFTSPEAREELGDVDRAQ
MAB_0579c|M.abscessus_ATCC_199      DAS---------------AAGEVDHVGRLMDGIFARAMAG-EDDPTDAQF
                                                           ::    :  ::  .    :        

Mb1581|M.bovis_AF2122/97            ELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG-------
Rv1556|M.tuberculosis_H37Rv         ELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG-------
MUL_1934|M.ulcerans_Agy99           ELWDLLPGYLIFRSIIPNRPPTPHTVQLLVDDFIMPGLTQATG-------
Mflv_4579|M.gilvum_PYR-GCK          ALCQLVGPLAFARMTGIRTITHNDCAN-IVDDFLTAHRKTDSDAKESKIA
Mvan_0323|M.vanbaalenii_PYR-1       ALCQLVGPLAFARMTGIRTITHNDCAN-IVDDFLTAHRKTDSDAKESKIA
MAV_3805|M.avium_104                ALCQLVGPLVFARMTGLRVITHQDCTR-IVEGFIAAQTGDQPAWVEASSP
MMAR_4834|M.marinum_M               ILCQLIGPVAFARLTGLRAIDRQDCER-IVDDFLVAHRRQADKPAQRAVS
TH_2910|M.thermoresistible__bu      AIIQLLGPIVFAKLTGMKTLTPADRVR-IVDDFLVAHRPPTPETA-----
MSMEG_1430|M.smegmatis_MC2_155      AAALLLGPIVLGKLSTLPEFDYATCVRSAVDGFLATHRRTVSESSNESAG
MAB_0579c|M.abscessus_ATCC_199      HIARVISDVWTSNMIAWLTRRASATDVSHRLDRTVRLLLGIT--------
                                        ::      .                  .                  

Mb1581|M.bovis_AF2122/97            ------------
Rv1556|M.tuberculosis_H37Rv         ------------
MUL_1934|M.ulcerans_Agy99           ------------
Mflv_4579|M.gilvum_PYR-GCK          TKQTGRPARLAR
Mvan_0323|M.vanbaalenii_PYR-1       TSRRAAPRV---
MAV_3805|M.avium_104                NQ----------
MMAR_4834|M.marinum_M               RKPVSRRSGSD-
TH_2910|M.thermoresistible__bu      ------------
MSMEG_1430|M.smegmatis_MC2_155      A-----------
MAB_0579c|M.abscessus_ATCC_199      ------------