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M. smegmatis MC2 155 MSMEG_3572 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 3632220 - 3632795
length: 191

VAARTHSADPRAERVRTRLHEAAFALAHERPVDELTVSDIVGRAGVSRQVFYQHFGDRDEAVAAAFATEF
TRAIDGLRGDPRARIVRLFDFAGEHRAMYRNVVPSAVTQRVVNAFRDELTPACAEIAEQGMTVVAPIAGL
SPEAVTRFLVGGFVEVLRSWMEDPDAGDARDLRDRVAAAFDTVNSLLTLNF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3572--100% (191)transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_4142-4e-0829.44% (197) transcriptional repressor, TetR family protein, putative
M. smegmatis MC2 155MSMEG_4333-1e-0729.34% (167) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0281c-6e-0726.34% (186) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_3329-8e-5259.46% (185) TetR family transcriptional regulator
M. tuberculosis H37RvRv0275c-4e-0726.34% (186) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2070c-7e-0728.18% (181) putative transcriptional regulator
M. marinum MMMAR_3144-7e-0728.07% (171) AcrR family transcriptional regulator
M. avium 104MAV_0586-3e-0727.13% (188) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0801fadD276e-0727.27% (187) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY
M. ulcerans Agy99MUL_1200-3e-0626.94% (193) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_3055-2e-5964.32% (185) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3329|M.gilvum_PYR-GCK          -----------MPERGRSADPRAQRVRNSLRDAAFALAR--EHPVDTISV
Mvan_3055|M.vanbaalenii_PYR-1       -----------MTERGRSADPRAERVHTRLREAAFAMAH--EHPVDRITV
MSMEG_3572|M.smegmatis_MC2_155      -----------MAARTHSADPRAERVRTRLHEAAFALAH--ERPVDELTV
Mb0281c|M.bovis_AF2122/97           ------MTRSDRPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
Rv0275c|M.tuberculosis_H37Rv        ------MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
MUL_1200|M.ulcerans_Agy99           ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
TH_0801|M.thermoresistible__bu      MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
MAB_2070c|M.abscessus_ATCC_199      ------MRSRNKRWGGRTGAERRAERRQQLIEAATEIWS--ESGWAAVTM
MMAR_3144|M.marinum_M               -------MSPARVYGGLSATQRDAQRRALLIDAAVALMG--KQGAAACTV
MAV_0586|M.avium_104                ------------------MARWEPDARARLVAAALDLFN--ERGYDQTTV
                                                              :     :.  :    .      ::

Mflv_3329|M.gilvum_PYR-GCK          GDIAARADVSRQVFYRHFRDRDHAVAAAFGHAFDDALAD-----------
Mvan_3055|M.vanbaalenii_PYR-1       GDLVGRAKVSRQVFYRHFRDRDDAVASAFSRAFTDATGG-----------
MSMEG_3572|M.smegmatis_MC2_155      SDIVGRAGVSRQVFYQHFGDRDEAVAAAFATEFTRAIDG-----------
Mb0281c|M.bovis_AF2122/97           RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTA---V
Rv0275c|M.tuberculosis_H37Rv        RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTA---V
MUL_1200|M.ulcerans_Agy99           RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVAT---V
TH_0801|M.thermoresistible__bu      RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAA---A
MAB_2070c|M.abscessus_ATCC_199      RGVCARTSLNDRYFYEDFKTRDELLVAAWDGVRNDMLGEVAALFTERANR
MMAR_3144|M.marinum_M               TAVCTESGVTSRYFYQQFRDRDALLRAMFTKISTTFQAVITKAIPDDT-V
MAV_0586|M.avium_104                AEIAERAGLTKSTFFRHFPDKRDVLAAGQDAIAQLLREGIAAAPAD---A
                                      :  .: :.   *:. *  :   :                         

Mflv_3329|M.gilvum_PYR-GCK          GAGQDARARILDLFGFAAAHPRLCRNVVPSTVHQHVLVTYRDALYAPCRR
Mvan_3055|M.vanbaalenii_PYR-1       ATGGDARTRILDLFEFAGAHPAMCRNIVPSTVNQHVLATYRDALFEPCQQ
MSMEG_3572|M.smegmatis_MC2_155      LRG-DPRARIVRLFDFAGEHRAMYRNVVPSAVTQRVVNAFRDELTPACAE
Mb0281c|M.bovis_AF2122/97           PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAM
Rv0275c|M.tuberculosis_H37Rv        PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAM
MUL_1200|M.ulcerans_Agy99           PPPEQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAM
TH_0801|M.thermoresistible__bu      PRRDQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESGALFAM
MAB_2070c|M.abscessus_ATCC_199      PPIETITAAIAIVVDGIARDPGRAHILLAQHVGSSPLQDRRAVALQEATQ
MMAR_3144|M.marinum_M               APQELAYAPIKALVQMIENDPSMARILFVESGAEPLLRQLRSELMSEFAE
MAV_0586|M.avium_104                TPLALVCSGLKSAAAAFTPFNKELAPRLRAAIAASAELQERNALKQIGLA
                                           : :                 .            *         

Mflv_3329|M.gilvum_PYR-GCK          IAGQS-MEVLDAVS--SLPAEAVTRFLVGGLVEVLRSWMEDP---DATDL
Mvan_3055|M.vanbaalenii_PYR-1       IAEQG-MAVLDTVA--PLPAEAVTRFLVGGFMEVLRSWMEDP---HATDL
MSMEG_3572|M.smegmatis_MC2_155      IAEQG-MTVVAPIA--GLSPEAVTRFLVGGFVEVLRSWMEDPDAGDARDL
Mb0281c|M.bovis_AF2122/97           LSGQHAVDTLHAPA--NDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQL
Rv0275c|M.tuberculosis_H37Rv        LSGQHAVDTLHAPA--NDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQL
MUL_1200|M.ulcerans_Agy99           LSGQHAGDALRIPA--NDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQL
TH_0801|M.thermoresistible__bu      LSGQHVGSTMQLPE--NERIKATSHFVVGGVGQTIGAWLAGEVRLSPEAL
MAB_2070c|M.abscessus_ATCC_199      LVVEASRPHLRHDAD-EMALRMDTLIAVGGFVEVITAWHSGLLAVTEKEV
MMAR_3144|M.marinum_M               LVLREARLHLDIPSEVIQVADLAATYGVGGLFEILRRWIDGQLNLSTEVL
MAV_0586|M.avium_104                LAVSEALQARGVPEP---AAALAAELGALAFKTAYARWAEPD---ESGDL
                                    :                      :   . ..      *           :

Mflv_3329|M.gilvum_PYR-GCK          NGRIQAALDTVD--ALLGIASAQKGSTRG---------------------
Mvan_3055|M.vanbaalenii_PYR-1       HARVSAALDTVD--ALLGTSPAQKGPTHG---------------------
MSMEG_3572|M.smegmatis_MC2_155      RDRVAAAFDTVN--SLLTLNF-----------------------------
Mb0281c|M.bovis_AF2122/97           VDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPAR
Rv0275c|M.tuberculosis_H37Rv        VDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPAR
MUL_1200|M.ulcerans_Agy99           VDQLASLLDELSDPRLYGLR----GTRAGATAASPAQ-------------
TH_0801|M.thermoresistible__bu      IDQLASVIDQLAKPELFRAD------------------------------
MAB_2070c|M.abscessus_ATCC_199      VAHTSRLAETLAQRYVVSD-------------------------------
MMAR_3144|M.marinum_M               IEHCAGFLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR-----------
MAV_0586|M.avium_104                GDMACQALRELHAAAADLG-------------------------------
                                              :                                       

Mflv_3329|M.gilvum_PYR-GCK          --
Mvan_3055|M.vanbaalenii_PYR-1       --
MSMEG_3572|M.smegmatis_MC2_155      --
Mb0281c|M.bovis_AF2122/97           RS
Rv0275c|M.tuberculosis_H37Rv        RS
MUL_1200|M.ulcerans_Agy99           --
TH_0801|M.thermoresistible__bu      --
MAB_2070c|M.abscessus_ATCC_199      --
MMAR_3144|M.marinum_M               --
MAV_0586|M.avium_104                --