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VSSSRVYGGVEAPDRQAERRNRLLDAGLDLLTSGPAPNLTVRGVCKHAGVVARYFYENFTDLDQLSAEVF DRAIGHVATTTQQAVDAAPLPEKTSAGIANLVRVIEGDPRIGTLMFGNNPANSVIAERRQAAWDMFAALS GQHMNKTYQATNDETLRAVSYYTVGGVGHTLAAWVSGQLKLPGTELVRVLTELLQPVRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4330 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2494c | - | 4e-34 | 37.31% (193) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1638 | - | 3e-21 | 32.83% (198) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 5e-44 | 46.39% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0331 | - | 3e-42 | 45.55% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 3e-43 | 45.88% (194) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0536 | - | 1e-41 | 44.79% (192) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 2e-44 | 46.67% (195) | FadD27 protein |
| M. smegmatis MC2 155 | MSMEG_0612 | - | 1e-41 | 44.85% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 7e-44 | 42.42% (198) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 6e-42 | 44.79% (192) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0409 | - | 6e-31 | 41.56% (154) | FadD27 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0281c|M.bovis_AF2122/97 ----MTRSD--RPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
Rv0275c|M.tuberculosis_H37Rv ----MTRSD--RPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
MAV_4882|M.avium_104 -MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLDLLGAEQQNIAAVTV
MMAR_0536|M.marinum_M ----------MRPYRGVEATERLAARRSQLLESGLELLGSSDRDIAELTV
MUL_1200|M.ulcerans_Agy99 ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
Mflv_0331|M.gilvum_PYR-GCK MGCMA----QVRPYRGVDAPARVAERRRRLLEAGLDLLGG-QLNPPELTV
Mvan_0409|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_0801|M.thermoresistible__bu MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
MSMEG_0612|M.smegmatis_MC2_155 -------MTPVRPYRGIEAADRLAQRRGQLLAAGLDLLGD---ENAEVTV
MAB_4330|M.abscessus_ATCC_1997 -------MSSSRVYGGVEAPDRQAERRNRLLDAGLDLLTSG--PAPNLTV
:
Mb0281c|M.bovis_AF2122/97 RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
Rv0275c|M.tuberculosis_H37Rv RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
MAV_4882|M.avium_104 RGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAELAATTQAAVTAVPAH
MMAR_0536|M.marinum_M RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
MUL_1200|M.ulcerans_Agy99 RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
Mflv_0331|M.gilvum_PYR-GCK RAICAQSGLAARYFYESFTDKDVFVGAVFDRVIADIATTTQAAVAAAPPR
Mvan_0409|M.vanbaalenii_PYR-1 RAICAQSGLAARYFYESFADKDVFVGAVFDWVVADIAATTQAAVAAAPVR
TH_0801|M.thermoresistible__bu RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAAAPRR
MSMEG_0612|M.smegmatis_MC2_155 RAVCQRAGLAARYFYESFGDKDAFVSEVYDWVIAEIAASTQAAVASVPLA
MAB_4330|M.abscessus_ATCC_1997 RGVCKHAGVVARYFYENFTDLDQLSAEVFDRAIGHVATTTQQAVDAAPLP
* :* .:*: *****.* * * : . *:* .:..:.:: * ** :.*
Mb0281c|M.bovis_AF2122/97 EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
Rv0275c|M.tuberculosis_H37Rv EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
MAV_4882|M.avium_104 EQTRAGMANIVRTITEDARVGRLLFSTQLADPVVVRKRAESSALFAMLSG
MMAR_0536|M.marinum_M EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
MUL_1200|M.ulcerans_Agy99 EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
Mflv_0331|M.gilvum_PYR-GCK EQSRQGMANIVRAISEDARVGRLLFNAHLDNPVVVRKRAESGALFALLSG
Mvan_0409|M.vanbaalenii_PYR-1 EQSRQGMANIVNTISDDIRVGRLLFNTRLDNPVVVRKRAESGALFALLSG
TH_0801|M.thermoresistible__bu DQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESGALFAMLSG
MSMEG_0612|M.smegmatis_MC2_155 EQTTAAMTNIVRTIADDPRIGRLLFSAKLSNEVVVRKRVEGIGFFAGLLG
MAB_4330|M.abscessus_ATCC_1997 EKTSAGIANLVRVIEGDPRIGTLMFGNNPANSVIAERRQAAWDMFAALSG
::: .::::*..: * *:* *:*. . .:..:* . :** * *
Mb0281c|M.bovis_AF2122/97 QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
Rv0275c|M.tuberculosis_H37Rv QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
MAV_4882|M.avium_104 QHVGDALRMPANDRIKAAAHFVVGGVAQTISAWLAGEVRLEPDQLVDQLA
MMAR_0536|M.marinum_M QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
MUL_1200|M.ulcerans_Agy99 QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
Mflv_0331|M.gilvum_PYR-GCK QHAGSALRLERNDRITSAAHFVVGGVAQTLSAWLAGDLTFTEAQLAAQLG
Mvan_0409|M.vanbaalenii_PYR-1 QHAGTALQVEPNERIRAAAHFAVGGVAQTLSAWLAGDLAFTPEQLAGQLG
TH_0801|M.thermoresistible__bu QHVGSTMQLPENERIKATSHFVVGGVGQTIGAWLAGEVRLSPEALIDQLA
MSMEG_0612|M.smegmatis_MC2_155 QHTVDALRLPENDQLRATAHFAVGGVTQTISAWLGGEVSFTPDELVQQLR
MAB_4330|M.abscessus_ATCC_1997 QHMNKTYQATNDETLRAVSYYTVGGVGHTLAAWVSGQLKLPGTELVRVLT
** : : :: : ::: **** :*:.**: *:: : * *
Mb0281c|M.bovis_AF2122/97 ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
MAV_4882|M.avium_104 ALLDELAEPALYRR--TETPAQS------------------------
MMAR_0536|M.marinum_M SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
MUL_1200|M.ulcerans_Agy99 SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
Mflv_0331|M.gilvum_PYR-GCK ALIDQLADPALYRD---------------------------------
Mvan_0409|M.vanbaalenii_PYR-1 ALLDQLADPTLYRD---------------------------------
TH_0801|M.thermoresistible__bu SVIDQLAKPELFRAD--------------------------------
MSMEG_0612|M.smegmatis_MC2_155 SLLDALANLQSRK----------------------------------
MAB_4330|M.abscessus_ATCC_1997 ELLQPVRR---------------------------------------
::: :