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MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDPDVVILDIGLP GVDGIEVCRQLRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESP AAVTPELSPPRVFGALRINVDGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRKQLLDTVWGDTWVGN DNIVDVHVGHLRQKLGDSPSQPRYVMTVRGVGYRMGTGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3339 | - | - | 100% (249) | putative sensory transduction protein |
| M. abscessus ATCC 19977 | MAB_4047c | - | 8e-50 | 44.05% (227) | sensory transduction protein RegX3 |
| M. abscessus ATCC 19977 | MAB_3591c | - | 5e-47 | 43.91% (230) | DNA-binding response regulator MtrA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0501 | regX3 | 5e-48 | 43.61% (227) | two component sensory transduction protein RegX3 |
| M. gilvum PYR-GCK | Mflv_3887 | - | 4e-94 | 69.66% (234) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 5e-48 | 43.61% (227) | two component sensory transduction protein RegX3 |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-47 | 43.48% (230) | putative two-component response regulator |
| M. marinum M | MMAR_0816 | regX3 | 1e-47 | 43.61% (227) | two-component sensory transduction protein RegX3 |
| M. avium 104 | MAV_4660 | - | 6e-48 | 43.17% (227) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_0937 | regX3 | 2e-49 | 44.49% (227) | DNA-binding response regulator RegX3 |
| M. thermoresistible (build 8) | TH_4312 | - | 1e-48 | 44.05% (227) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 8e-48 | 43.61% (227) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_3674 | - | 7e-99 | 72.61% (241) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0501|M.bovis_AF2122/97 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
Rv0491|M.tuberculosis_H37Rv -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MAV_4660|M.avium_104 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MMAR_0816|M.marinum_M -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MUL_4560|M.ulcerans_Agy99 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MSMEG_0937|M.smegmatis_MC2_155 --------------------MLIVEDEESLADPLAFLLRKEGFEATVVGD
TH_4312|M.thermoresistible__bu -----------------MTSVLIVEDEESLADPLAFLLRKEGFETTIVTD
MLBr_00773|M.leprae_Br4923 ---MD----------IMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGD
Mflv_3887|M.gilvum_PYR-GCK MSTMDHPQGSPSE-HSRGYRALVVDDEVPLAEVVASYLQREQFDAVVADN
Mvan_3674|M.vanbaalenii_PYR-1 ---MEKPAATP----SAGYRALVVDDEVPLAEVVASYLRREQFDVSLAHS
MAB_3339|M.abscessus_ATCC_1997 ---MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHD
*:*:*: .**: :: *: * *:. : .
Mb0501|M.bovis_AF2122/97 GPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
Rv0491|M.tuberculosis_H37Rv GPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MAV_4660|M.avium_104 GSAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MMAR_0816|M.marinum_M GPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MUL_4560|M.ulcerans_Agy99 GPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MSMEG_0937|M.smegmatis_MC2_155 GPSALAEFERSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
TH_4312|M.thermoresistible__bu GPSALAEFERSGADIILLDLMLPGMSGTDVCRRLRAKSKVPVIMVTARDS
MLBr_00773|M.leprae_Br4923 GTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTD
Mflv_3887|M.gilvum_PYR-GCK GVDAIALARDFDPDVVILDLGLPGIDGLEVCRSLRTFSDAYVVMLTARDT
Mvan_3674|M.vanbaalenii_PYR-1 GADALAQAREIDPDVVILDLALPGIDGVEVCRQLRTFSDAYVVMLTARDT
MAB_3339|M.abscessus_ATCC_1997 GRRALDLAREVDPDVVILDIGLPGVDGIEVCRQLRVFSDAYVVMLTARDT
* *: .*:::**: ***:.* :**: **. * . ::*:**:
Mb0501|M.bovis_AF2122/97 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEMSDGVLE
Rv0491|M.tuberculosis_H37Rv EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEMSDGVLE
MAV_4660|M.avium_104 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEISDGVLE
MMAR_0816|M.marinum_M EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLE
MUL_4560|M.ulcerans_Agy99 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLE
MSMEG_0937|M.smegmatis_MC2_155 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADNDDAGADDGVLE
TH_4312|M.thermoresistible__bu EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSVLE
MLBr_00773|M.leprae_Br4923 TVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-----EPAEMLS
Mflv_3887|M.gilvum_PYR-GCK ELDTVLGLTVGADDYVTKPFSPRELVARIRAMLRRPRLLQSPPTGADR-E
Mvan_3674|M.vanbaalenii_PYR-1 EMDTIVGLSVGADDYVTKPFSPRELVARIRAMLRRPRTVATPISAATAAD
MAB_3339|M.abscessus_ATCC_1997 EVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESPAAVTP-E
:* ::** *****: **:..:*::**:** *** .
Mb0501|M.bovis_AF2122/97 SGP------VRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRG
Rv0491|M.tuberculosis_H37Rv SGP------VRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRG
MAV_4660|M.avium_104 SGP------VRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRG
MMAR_0816|M.marinum_M SGP------VRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRG
MUL_4560|M.ulcerans_Agy99 SGP------VRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRG
MSMEG_0937|M.smegmatis_MC2_155 AGP------VRMDVERHVVSVNGEPITLPLKEFDLLEYLMRNSGRVLTRG
TH_4312|M.thermoresistible__bu AGP------VRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRG
MLBr_00773|M.leprae_Br4923 IAD------VDIDVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRD
Mflv_3887|M.gilvum_PYR-GCK VTPPRRFGALSIDVAAREVRIADDPILLTRTEFDILQALSGRPGIVLSRR
Mvan_3674|M.vanbaalenii_PYR-1 EPPPRAFGPLAIDVAGRQVFIDDEPVLLTRTEFDILAALSSRPAVVFSRR
MAB_3339|M.abscessus_ATCC_1997 LSPPRVFGALRINVDGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRK
: ::* : * : *. **::* * .. *::*
Mb0501|M.bovis_AF2122/97 QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE
Rv0491|M.tuberculosis_H37Rv QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE
MAV_4660|M.avium_104 QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE
MMAR_0816|M.marinum_M QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE
MUL_4560|M.ulcerans_Agy99 QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE
MSMEG_0937|M.smegmatis_MC2_155 QLIDRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLE
TH_4312|M.thermoresistible__bu QLIDRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLE
MLBr_00773|M.leprae_Br4923 VLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAG
Mflv_3887|M.gilvum_PYR-GCK QLLEIIRDEPWVGNDQLVDVHIGHLRRKLGDDAARPRYIATVRGVGYRMG
Mvan_3674|M.vanbaalenii_PYR-1 QLLEAVWGDSWGGNEHLVDVHIGHLRRKLADDPADPRYVITVRGVGYRMG
MAB_3339|M.abscessus_ATCC_1997 QLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRGVGYRMG
*:: : . .: . ::**: :** *: .. * : ****:**:
Mb0501|M.bovis_AF2122/97 G--
Rv0491|M.tuberculosis_H37Rv G--
MAV_4660|M.avium_104 G--
MMAR_0816|M.marinum_M G--
MUL_4560|M.ulcerans_Agy99 G--
MSMEG_0937|M.smegmatis_MC2_155 G--
TH_4312|M.thermoresistible__bu G--
MLBr_00773|M.leprae_Br4923 PP-
Mflv_3887|M.gilvum_PYR-GCK TGA
Mvan_3674|M.vanbaalenii_PYR-1 SGQ
MAB_3339|M.abscessus_ATCC_1997 TGS