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M. gilvum PYR-GCK Mflv_3212 (-)

annotation: MerR family transcriptional regulator
coordinates: 3409903 - 3410292
length: 129

RIGKLAEATGATTATLRYYEDEGLLPPAERSPAGYRDYAADTIARVGFIRRGQAAGFSLAQIRQILDIRD
SGHAPCTHVRDLLDIRLTDLDEQISALVALRETIARLRQGAESVDPESCSADDVCRYL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3212--100% (129)MerR family transcriptional regulator
M. gilvum PYR-GCKMflv_1922-1e-0935.58% (104) MerR family transcriptional regulator
M. gilvum PYR-GCKMflv_0148-4e-0829.13% (127) MerR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3367-3e-2643.65% (126) MerR family transcriptional regulator
M. tuberculosis H37RvRv3334-3e-2643.65% (126) MerR family transcriptional regulator
M. leprae Br4923MLBr_02075-9e-0538.46% (65) hypothetical protein MLBr_02075
M. abscessus ATCC 19977MAB_2246-4e-0934.78% (115) thiol-specific antioxidant related protein/peroxidoxin BcpB
M. marinum MMMAR_2990hspR_25e-0739.02% (82) heat shock protein transcriptional repressor HspR_2
M. avium 104MAV_3222-9e-0932.77% (119) transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_1969-7e-1136.11% (108) MerR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_0931soxR1e-0832.38% (105) redox-sensitive transcriptional activator SoxR
M. ulcerans Agy99MUL_0011-7e-0727.08% (96) transcriptional regulator
M. vanbaalenii PYR-1Mvan_4935-2e-1135.09% (114) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3367|M.bovis_AF2122/97            -----------------MKISEVAALT-----NTSTKTLRFYENSGLLPP
Rv3334|M.tuberculosis_H37Rv         -----------------MKISEVAALT-----NTSTKTLRFYENSGLLPP
Mflv_3212|M.gilvum_PYR-GCK          -----------------MRIGKLAEAT-----GATTATLRYYEDEGLLPP
MSMEG_1969|M.smegmatis_MC2_155      -----------------MKIGELARST-----GVSVRSLRYYEQRRLIS-
MMAR_2990|M.marinum_M               MADRPGHAGGPAPDVGVYGISVTAELS-----GIAVQSLRLYERHGLVT-
MAB_2246|M.abscessus_ATCC_1997      -----------------MQISELARRA-----GVSLKAVRYYERLGLVM-
TH_0931|M.thermoresistible__bu      ------------MGAHELTPSEMSARS-----GVAVSALHFYEREGLIT-
MAV_3222|M.avium_104                ----------------MLTIGEVARRS-----GVAATTLRYYEQIGLLPA
MUL_0011|M.ulcerans_Agy99           --------------MDGLTVGQVAERF-----GITVRTLHHYDEIGLLIP
Mvan_4935|M.vanbaalenii_PYR-1       --MVIVSSNPDCLESHGVSIAEAAQRT-----GLSRHTLRYYERAGLIES
MLBr_02075|M.leprae_Br4923          ------MSAPDSPALVGMSIGAVLDLLRSDFPDVTISKIRFLEAEGLVT-
                                                        .           . :   ::  :   *:  

Mb3367|M.bovis_AF2122/97            PARTASGYRNYGPEIVDRLRFIHRGQAAG-LALQEVRQILAIH-DRGEAP
Rv3334|M.tuberculosis_H37Rv         PARTASGYRNYGPEIVDRLRFIHRGQAAG-LALQEVRQILAIH-DRGEAP
Mflv_3212|M.gilvum_PYR-GCK          AERSPAGYRDYAADTIARVGFIRRGQAAG-FSLAQIRQILDIR-DSGHAP
MSMEG_1969|M.smegmatis_MC2_155      ARRTPGGQRIYDEDAVERVALIKELFAAG-ISSDGVVQMLPCI-DSGTAT
MMAR_2990|M.marinum_M               PARSEGGTRRYSADDLVRLQRVSVLIEAG-INLAGISRILNLE-DDNAAL
MAB_2246|M.abscessus_ATCC_1997      PSRLGNGYRDYTDDDLQIVGEIRSLAAAG-ISPSLARPFIECL-REGHDH
TH_0931|M.thermoresistible__bu      SRRTAGNQRRYPREMLRRVAFIRMSQRLG-IPLARIREALATLPSDRVPT
MAV_3222|M.avium_104                PTRLG-GQRRYDEAVLSRLEVIALCKTAG-FALDEIQRLFADD----APG
MUL_0011|M.ulcerans_Agy99           SRRAASGYRVYTSADLTRLSQVIVYRRLE-LPLDEIARLLDEG--NAVSH
Mvan_4935|M.vanbaalenii_PYR-1       VERSTSGRRQYAASDLDWFAFLVRLRQTG-MPITQMQQFARLR-ADGAAT
MLBr_02075|M.leprae_Br4923          PQRSASGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPS
                                      *   . * :       .  :        :                   

Mb3367|M.bovis_AF2122/97            CAH------VRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEH
Rv3334|M.tuberculosis_H37Rv         CAH------VRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEH
Mflv_3212|M.gilvum_PYR-GCK          CTH------VRDLLDIRLTDLDEQISALVALRETIARLRQGAESVDPESC
MSMEG_1969|M.smegmatis_MC2_155      PAM------VERLVCER-ARIDAEMKRLAATRDRLDQIIVETRRHVRSRA
MMAR_2990|M.marinum_M               AAA------NCDLLASN--------RSLRDAARAAVRLMNHGRSAENGEG
MAB_2246|M.abscessus_ATCC_1997      SDD------CPSALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTF
TH_0931|M.thermoresistible__bu      SKD------WAELSAGWRADLDERILHLQRLRDNLADCIGCGCLSLKTCA
MAV_3222|M.avium_104                RPA------SRALARAKLAQIDAQLDSLTRARAVIEWGMRCTCPSIDACT
MUL_0011|M.ulcerans_Agy99           LVR------QRERVMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELF
Mvan_4935|M.vanbaalenii_PYR-1       LEQ------RRQLLDEHRRHVEAAIAVQQGHLAALTDKIAHYEQLITGRQ
MLBr_02075|M.leprae_Br4923          FGSPYVAPRLFSVTGGPGAGVGSGVGSDIPAVSPAGVRLSREDLLDRSGV
                                                                                      

Mb3367|M.bovis_AF2122/97            DHSTVCWILESDLDEPTAIEVSDIHA------------------------
Rv3334|M.tuberculosis_H37Rv         DHSTVCWILESDLDEPTAIEVSDIHA------------------------
Mflv_3212|M.gilvum_PYR-GCK          SADDVCRYL-----------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      AAG-----------------------------------------------
MMAR_2990|M.marinum_M               GDTS----------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      TEEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMATGGCAVRLR
TH_0931|M.thermoresistible__bu      LSNPDDALAARGPGAARL--------------------------------
MAV_3222|M.avium_104                CGIHPTRPAPVGPDVRSARRF-----------------------------
MUL_0011|M.ulcerans_Agy99           GDGFDDYRVETEQKWGETAEWKESQRRTKSYGKDEWVRIKAEG-------
Mvan_4935|M.vanbaalenii_PYR-1       GDQT----------------------------------------------
MLBr_02075|M.leprae_Br4923          ADDLLTALLKAGVITTGPGGFFDEHAIVILQCARALS-------------
                                                                                      

Mb3367|M.bovis_AF2122/97            --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3212|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_2990|M.marinum_M               --------------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      GLPEGRTVLYLYPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELR
TH_0931|M.thermoresistible__bu      --------------------------------------------------
MAV_3222|M.avium_104                --------------------------------------------------
MUL_0011|M.ulcerans_Agy99           ---------------------------QAIEKALSDAFRAGLPADSEEAM
Mvan_4935|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02075|M.leprae_Br4923          --------------------------EYGVEPRHLRAFRSAADRQSDLIV
                                                                                      

Mb3367|M.bovis_AF2122/97            --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3212|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_2990|M.marinum_M               --------------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      AAGAQQVWGLSSQDTDYQAEVVRRLRLPFHMLSDPDFTLAEALHLPTFAA
TH_0931|M.thermoresistible__bu      --------------------------------------------------
MAV_3222|M.avium_104                --------------------------------------------------
MUL_0011|M.ulcerans_Agy99           NAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPGLAA
Mvan_4935|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02075|M.leprae_Br4923          QIAGPIVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRGVLHR---
                                                                                      

Mb3367|M.bovis_AF2122/97            ----------------------------------------------
Rv3334|M.tuberculosis_H37Rv         ----------------------------------------------
Mflv_3212|M.gilvum_PYR-GCK          ----------------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      ----------------------------------------------
MMAR_2990|M.marinum_M               ----------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      VGHPRLYARITLVVRDGRIEQVFYPIFPPDTHAQQVLEWLTSHPMD
TH_0931|M.thermoresistible__bu      ----------------------------------------------
MAV_3222|M.avium_104                ----------------------------------------------
MUL_0011|M.ulcerans_Agy99           YCREAIHANANRAGG-------------------------------
Mvan_4935|M.vanbaalenii_PYR-1       ----------------------------------------------
MLBr_02075|M.leprae_Br4923          ----------------------------------------------