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VIVSSNPDCLESHGVSIAEAAQRTGLSRHTLRYYERAGLIESVERSTSGRRQYAASDLDWFAFLVRLRQT GMPITQMQQFARLRADGAATLEQRRQLLDEHRRHVEAAIAVQQGHLAALTDKIAHYEQLITGRQGDQT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4935 | - | - | 100% (139) | MerR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4811 | - | 4e-07 | 29.82% (114) | MerR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0637 | - | 4e-06 | 34.09% (88) | MerR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 7e-11 | 33.04% (115) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3212 | - | 2e-11 | 35.09% (114) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 7e-11 | 33.04% (115) | MerR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02493 | hspR | 5e-06 | 30.61% (98) | heat shock regulator |
| M. abscessus ATCC 19977 | MAB_4121c | - | 3e-18 | 37.82% (119) | MerR family transcriptional regulator |
| M. marinum M | MMAR_0009 | - | 4e-07 | 31.00% (100) | transcriptional regulator |
| M. avium 104 | MAV_4105 | - | 6e-06 | 31.25% (96) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_5450 | soxR | 1e-06 | 29.46% (112) | redox-sensitive transcriptional activator SoxR |
| M. thermoresistible (build 8) | TH_0931 | soxR | 4e-06 | 28.07% (114) | redox-sensitive transcriptional activator SoxR |
| M. ulcerans Agy99 | MUL_0011 | - | 3e-07 | 31.00% (100) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4935|M.vanbaalenii_PYR-1 --MVIVSSNPDCLESHGVSIAEAAQRTGLSRHTLRYYERAGLIESVERST
MAB_4121c|M.abscessus_ATCC_199 ----MSTSEP---SHAGFPISHVAQRTGLSIDALRWFEREGLFPRVPRDA
MLBr_02493|M.leprae_Br4923 -MMTRNSRDPRQQESRTFLISAAAELAGMHAQTLRTYDRLGLVS-PSRAS
MAV_4105|M.avium_104 MADRRGNAGAPASDQGVYGISVAAELSGIAVQSLRLYERHGLVT-PARSQ
Mb3367|M.bovis_AF2122/97 -----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTA
Rv3334|M.tuberculosis_H37Rv -----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTA
Mflv_3212|M.gilvum_PYR-GCK -----------------MRIGKLAEATGATTATLRYYEDEGLLPPAERSP
MMAR_0009|M.marinum_M --------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAA
MUL_0011|M.ulcerans_Agy99 --------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAA
MSMEG_5450|M.smegmatis_MC2_155 --------------MHELTPGELAQRSGVAVSALHFYEREGLIT-SRRTS
TH_0931|M.thermoresistible__bu ------------MGAHELTPSEMSARSGVAVSALHFYEREGLIT-SRRTA
. : . :*: :: **. *
Mvan_4935|M.vanbaalenii_PYR-1 SGRRQYAASDLDWFAFLVRLRQ-TGMPITQMQ-------QFARLRADG--
MAB_4121c|M.abscessus_ATCC_199 GGRRRFSDDDIERVQLMLRLRR-TGMPVRDMR-------RFIELLAGG--
MLBr_02493|M.leprae_Br4923 GGGRRYSQHDVELLRQVQRLSQNEGVNLAGIK-------RIIELTNQ---
MAV_4105|M.avium_104 GGTRRYSADDLARLKRISKLVD-AGVNLAGVA-------RILALEDD---
Mb3367|M.bovis_AF2122/97 SGYRNYGPEIVDRLRFIHRGQA-AGLALQEVR-------QILAIHDRG--
Rv3334|M.tuberculosis_H37Rv SGYRNYGPEIVDRLRFIHRGQA-AGLALQEVR-------QILAIHDRG--
Mflv_3212|M.gilvum_PYR-GCK AGYRDYAADTIARVGFIRRGQA-AGFSLAQIR-------QILDIRDSG--
MMAR_0009|M.marinum_M SGYRVYTSADLTRLSQVIVYRR-LELPLDEIARLLDEGNAVSHLVRQRER
MUL_0011|M.ulcerans_Agy99 SGYRVYTSADLTRLSQVIVYRR-LELPLDEIARLLDEGNAVSHLVRQRER
MSMEG_5450|M.smegmatis_MC2_155 GNQRRYARETLRRVAFIRMSQR-LGIPLSRIR------EALSTLPND---
TH_0931|M.thermoresistible__bu GNQRRYPREMLRRVAFIRMSQR-LGIPLARIR------EALATLPSD---
.. * : : . : . : : . :
Mvan_4935|M.vanbaalenii_PYR-1 ---------------------------------------------AATLE
MAB_4121c|M.abscessus_ATCC_199 ---------------------------------------------EETHA
MLBr_02493|M.leprae_Br4923 ---------------------------------------------VEALQ
MAV_4105|M.avium_104 ---------------------------------------------NATLS
Mb3367|M.bovis_AF2122/97 ---------------------------------------------EAPCA
Rv3334|M.tuberculosis_H37Rv ---------------------------------------------EAPCA
Mflv_3212|M.gilvum_PYR-GCK ---------------------------------------------HAPCT
MMAR_0009|M.marinum_M VMARLDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAETEQ
MUL_0011|M.ulcerans_Agy99 VMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQ
MSMEG_5450|M.smegmatis_MC2_155 --------------------------------------------RVPTSK
TH_0931|M.thermoresistible__bu --------------------------------------------RVPTSK
.
Mvan_4935|M.vanbaalenii_PYR-1 QRRQ------------------------------------LLDEHRRHVE
MAB_4121c|M.abscessus_ATCC_199 ERLE------------------------------------LLFAQRVRIL
MLBr_02493|M.leprae_Br4923 LKLQ------------------------------------ELTDELVMLR
MAV_4105|M.avium_104 AANT------------------------------------DLRSTNRALR
Mb3367|M.bovis_AF2122/97 HVRQ------------------------------------LLSTRIDEVR
Rv3334|M.tuberculosis_H37Rv HVRQ------------------------------------LLSTRIDEVR
Mflv_3212|M.gilvum_PYR-GCK HVRD------------------------------------LLDIRLTDLD
MMAR_0009|M.marinum_M KWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPADSE
MUL_0011|M.ulcerans_Agy99 KWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSE
MSMEG_5450|M.smegmatis_MC2_155 DWAR------------------------------------LSAGWRQDLD
TH_0931|M.thermoresistible__bu DWAE------------------------------------LSAGWRADLD
Mvan_4935|M.vanbaalenii_PYR-1 AAIAVQQGHLAALTDKIAHYEQLITGRQGDQT------------------
MAB_4121c|M.abscessus_ATCC_199 AAMERLTEDLRVVDFKVAYYTESVNGASAQSAGGKKN-------------
MLBr_02493|M.leprae_Br4923 ANQRRDLAVVPKSTALVLWQPRKPR-------------------------
MAV_4105|M.avium_104 EAAKTADGDAATG-------------------------------------
Mb3367|M.bovis_AF2122/97 AQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVS
Rv3334|M.tuberculosis_H37Rv AQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVS
Mflv_3212|M.gilvum_PYR-GCK EQISALVALRETIARLRQGAESVDPESCSADDVCRYL-------------
MMAR_0009|M.marinum_M EAMNAAEQHRRHVNRWFYDCPPAFHRSLGDMYVSDPRYIATYDESFGLPG
MUL_0011|M.ulcerans_Agy99 EAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPG
MSMEG_5450|M.smegmatis_MC2_155 DRIMHLQRLRDNLT----GCIGCGCLSLKTCQLTNPGDVLAERG----PG
TH_0931|M.thermoresistible__bu ERILHLQRLRDNLA----DCIGCGCLSLKTCALSNPDDALAARG----PG
Mvan_4935|M.vanbaalenii_PYR-1 ------------------
MAB_4121c|M.abscessus_ATCC_199 ------------------
MLBr_02493|M.leprae_Br4923 ------------------
MAV_4105|M.avium_104 ------------------
Mb3367|M.bovis_AF2122/97 DIHA--------------
Rv3334|M.tuberculosis_H37Rv DIHA--------------
Mflv_3212|M.gilvum_PYR-GCK ------------------
MMAR_0009|M.marinum_M LAAYCREAIHANANRTGG
MUL_0011|M.ulcerans_Agy99 LAAYCREAIHANANRAGG
MSMEG_5450|M.smegmatis_MC2_155 AARL--------------
TH_0931|M.thermoresistible__bu AARL--------------