For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb3367 (-)

annotation: MerR family transcriptional regulator
coordinates: 3678506 - 3678946
length: 146

MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIH
DRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIE
VSDIHA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3367--100% (146)MerR family transcriptional regulator
M. bovis AF2122 / 97Mb0361hspR2e-0532.32% (99) HEAT shock protein transcriptional regulator HspR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3212-5e-2643.65% (126) MerR family transcriptional regulator
M. tuberculosis H37RvRv3334-1e-81100.00% (146) MerR family transcriptional regulator
M. leprae Br4923MLBr_02493hspR8e-0533.78% (74) heat shock regulator
M. abscessus ATCC 19977MAB_4723c-7e-0833.66% (101) MerR family transcriptional regulator
M. marinum MMMAR_0009-6e-0629.75% (121) transcriptional regulator
M. avium 104MAV_3222-8e-0934.69% (98) transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_1447-2e-0940.74% (81) transcriptional regulator, MerR family protein
M. thermoresistible (build 8)TH_0931soxR9e-0733.33% (108) redox-sensitive transcriptional activator SoxR
M. ulcerans Agy99MUL_0011-3e-0632.38% (105) transcriptional regulator
M. vanbaalenii PYR-1Mvan_4691-8e-1237.29% (118) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3367|M.bovis_AF2122/97            ----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTAS
Rv3334|M.tuberculosis_H37Rv         ----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTAS
Mflv_3212|M.gilvum_PYR-GCK          ----------------MRIGKLAEATGATTATLRYYEDEGLLPPAERSPA
MAV_3222|M.avium_104                ---------------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTRLG-
Mvan_4691|M.vanbaalenii_PYR-1       ---------------MIDISAVARRSGLPTSTLRFYEEKGLIASVGRRS-
MMAR_0009|M.marinum_M               -------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAAS
MUL_0011|M.ulcerans_Agy99           -------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAAS
MSMEG_1447|M.smegmatis_MC2_155      ------MTVPGTDQDLLQIGEVAARTELSVKTIRHYDEVGLVVPSARSAG
TH_0931|M.thermoresistible__bu      -----------MGAHELTPSEMSARSGVAVSALHFYEREGLITS-RRTAG
MLBr_02493|M.leprae_Br4923          MMTRNSRDPRQQESRTFLISAAAELAGMHAQTLRTYDRLGLVSPSRASGG
MAB_4723c|M.abscessus_ATCC_199      -----MATDAEGVAVGWSTRELADLAGTSLRTVRHYHDVGLLGEPERRPN
                                                          :        ::: *.  **:        

Mb3367|M.bovis_AF2122/97            GYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIH-DRGEAPCAHVRQL
Rv3334|M.tuberculosis_H37Rv         GYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIH-DRGEAPCAHVRQL
Mflv_3212|M.gilvum_PYR-GCK          GYRDYAADTIARVGFIRRGQAAGFSLAQIRQILDIR-DSGHAPCTHVRDL
MAV_3222|M.avium_104                GQRRYDEAVLSRLEVIALCKTAGFALDEIQRLFAD----DAPGRPASRAL
Mvan_4691|M.vanbaalenii_PYR-1       RRRLFGPDVFDRLALITLGRAAGFSLDEIATMLTL----GGP-RQIDRKA
MMAR_0009|M.marinum_M               GYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDE----GNAVSHLVRQR
MUL_0011|M.ulcerans_Agy99           GYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDE----GNAVSHLVRQR
MSMEG_1447|M.smegmatis_MC2_155      GFRLYTTDDVRRLMAIRRMKPLGFTLDEMGRLLDA-----LAVLDKPAAT
TH_0931|M.thermoresistible__bu      NQRRYPREMLRRVAFIRMSQRLGIPLARIREALATL-PSDRVPTSKDWAE
MLBr_02493|M.leprae_Br4923          GRRYSQHDVELLRQVQRLSQNEGVNLAGIKRIIELT-NQVEALQLKLQEL
MAB_4723c|M.abscessus_ATCC_199      GYKSYGVAHLVRVLQIKRLTGLGLSLKQIAEMDEADENQQEALRALDAEL
                                      :                    . *  :                     

Mb3367|M.bovis_AF2122/97            LST--RIDEVRAQIAELIALEGHLQTLLDHASYGPPTE------------
Rv3334|M.tuberculosis_H37Rv         LST--RIDEVRAQIAELIALEGHLQTLLDHASYGPPTE------------
Mflv_3212|M.gilvum_PYR-GCK          LDI--RLTDLDEQISALVALRETIARLRQGAESVDPES------------
MAV_3222|M.avium_104                ARA--KLAQIDAQLDSLTRARAVIEWGMRCTCPS----------------
Mvan_4691|M.vanbaalenii_PYR-1       LTT--RAAEIDSTIERLTAISTALKHAAACPAPDHMECPTFRGY------
MMAR_0009|M.marinum_M               ER---VMARLDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYR
MUL_0011|M.ulcerans_Agy99           ER---VMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYR
MSMEG_1447|M.smegmatis_MC2_155      AAE--RATAAEVVSDCHTRAQEACDRLTRHLAYAR---------------
TH_0931|M.thermoresistible__bu      LSAG-WRADLDERILHLQRLRDNLADCIGCGCLS----------------
MLBr_02493|M.leprae_Br4923          TDEL-VMLRANQRRDLAVVPKSTALVLWQPRKPR----------------
MAB_4723c|M.abscessus_ATCC_199      AATIDRLQGVRDELAQIFSSEIAADLPREFGAAAVDMNFSETDRSLAFVM
                                                                                      

Mb3367|M.bovis_AF2122/97            -----------------------------------------HDHSTVCWI
Rv3334|M.tuberculosis_H37Rv         -----------------------------------------HDHSTVCWI
Mflv_3212|M.gilvum_PYR-GCK          -----------------------------------------CSADDVCRY
MAV_3222|M.avium_104                ------------------------------------------IDACTCGI
Mvan_4691|M.vanbaalenii_PYR-1       ------------------------------------------LDLAAAGL
MMAR_0009|M.marinum_M               AETEQKWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGL
MUL_0011|M.ulcerans_Agy99           VETEQKWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGL
MSMEG_1447|M.smegmatis_MC2_155      -----------------------------------------ELTEQLAKV
TH_0931|M.thermoresistible__bu      ------------------------------------------LKTCALSN
MLBr_02493|M.leprae_Br4923          --------------------------------------------------
MAB_4723c|M.abscessus_ATCC_199      SRVLGPAG-------------------LQAFVGMFLDQQDRALDHELENL
                                                                                      

Mb3367|M.bovis_AF2122/97            LESDLDEPTAIEVSDIHA--------------------------------
Rv3334|M.tuberculosis_H37Rv         LESDLDEPTAIEVSDIHA--------------------------------
Mflv_3212|M.gilvum_PYR-GCK          L-------------------------------------------------
MAV_3222|M.avium_104                H---PTRPAPVGPDVRSARRF-----------------------------
Mvan_4691|M.vanbaalenii_PYR-1       FSESPPRKSPPKPTIKKQVRLGAGQPIRGE--------------------
MMAR_0009|M.marinum_M               PADSEEAMNAAEQHRRHVNRWFYDCPPAFHRSLGDMYVSDPRYIATYDES
MUL_0011|M.ulcerans_Agy99           PADSEEAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDES
MSMEG_1447|M.smegmatis_MC2_155      RG------------------------------------------------
TH_0931|M.thermoresistible__bu      PDDALAARGPGAARL-----------------------------------
MLBr_02493|M.leprae_Br4923          --------------------------------------------------
MAB_4723c|M.abscessus_ATCC_199      PADAGERTRADLAERMSLHAKRLYADHPGMLNSTADAPRGQRFAESTVAR
                                                                                      

Mb3367|M.bovis_AF2122/97            ----------------------------
Rv3334|M.tuberculosis_H37Rv         ----------------------------
Mflv_3212|M.gilvum_PYR-GCK          ----------------------------
MAV_3222|M.avium_104                ----------------------------
Mvan_4691|M.vanbaalenii_PYR-1       ----------------------------
MMAR_0009|M.marinum_M               FGLPGLAAYCREAIHANANRTGG-----
MUL_0011|M.ulcerans_Agy99           FGLPGLAAYCREAIHANANRAGG-----
MSMEG_1447|M.smegmatis_MC2_155      ----------------------------
TH_0931|M.thermoresistible__bu      ----------------------------
MLBr_02493|M.leprae_Br4923          ----------------------------
MAB_4723c|M.abscessus_ATCC_199      ALLDLFNPAQLDVLIRVGAAVRSEPGEG