For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GNEMHASIRAALAAGVTTLTASALAFAPPPQPPAAQALSVQPLSIASEMVSAASFTAGSTRILPVTDPRA LAALTAFTQPWPGTPSDAADPTDLATVTTADEPLEDPVALNAASDVIDTVYAFTRYWANYVSLELGPWLI NWVPFGYLISDQILIWYPNFVLPVVDSFVYDFLDPVVNDPLNLEVWAQGIGSIIDTAVAGVRNGVTAEIQ YILDFGWFPFPLPPLPSFPVPGAAGASAESADADVQLASVDEADAAGAVEDAVEGAEGGAAEAVEVDGDD IVAQKPADVSGEAVDEALVEEESVEEESVDVVDEESVEAVDDETDQVEETVDEESAEDGATTDDEPTDED APAGSDSGDDTSGSETE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2738 | - | - | 100% (368) | hypothetical protein Mflv_2738 |
| M. gilvum PYR-GCK | Mflv_4518 | - | 4e-08 | 31.91% (141) | hypothetical protein Mflv_4518 |
| M. gilvum PYR-GCK | Mflv_5244 | - | 8e-08 | 36.17% (94) | hypothetical protein Mflv_5244 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1205c | PE12 | 2e-06 | 22.46% (236) | PE family protein |
| M. tuberculosis H37Rv | Rv1172c | PE12 | 2e-06 | 22.46% (236) | PE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2679 | - | 4e-27 | 30.79% (354) | hypothetical protein MAB_2679 |
| M. marinum M | MMAR_4280 | - | 3e-07 | 28.95% (152) | PE family protein |
| M. avium 104 | MAV_3172 | - | 5e-07 | 27.20% (125) | prolipoprotein diacylglyceryl transferase |
| M. smegmatis MC2 155 | MSMEG_5127 | - | 1e-21 | 28.44% (327) | hypothetical protein MSMEG_5127 |
| M. thermoresistible (build 8) | TH_3064 | - | 1e-12 | 27.27% (308) | PUTATIVE putative PE family protein |
| M. ulcerans Agy99 | MUL_1019 | - | 2e-08 | 29.61% (152) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_3794 | - | 2e-79 | 46.29% (404) | hypothetical protein Mvan_3794 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1205c|M.bovis_AF2122/97 -----MSFVFAAPEALAAAAADMAGIGSTLNAANVVA-------------
Rv1172c|M.tuberculosis_H37Rv -----MSFVFAAPEALAAAAADMAGIGSTLNAANVVA-------------
MMAR_4280|M.marinum_M -----MSYVAAVPEALTAAASDVAGIGTTISSANAAA-------------
MUL_1019|M.ulcerans_Agy99 -----MSYVATVPEALTAAASDAAGIGTTISSANAAA-------------
Mflv_2738|M.gilvum_PYR-GCK ---MGNEMHASIRAALAAGVTTLTASALAFAPPPQPP-------------
Mvan_3794|M.vanbaalenii_PYR-1 -------MNVSARAALAAGVTALTGGALMFTPSVLPATMSTVEVVRPVA-
MAB_2679|M.abscessus_ATCC_1997 -------MDRTANPLFKAGMAAITATALIVAPAVTPPTRQSIPLP-----
TH_3064|M.thermoresistible__bu -------------------VAAVGAAAVAFAPVQALPP------------
MSMEG_5127|M.smegmatis_MC2_155 -------MTVSVRAYLMAGAAAATATTIALTSVQVTPP------------
MAV_3172|M.avium_104 MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEARGG
. . . .
Mb1205c|M.bovis_AF2122/97 --AVPTTGVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQ
Rv1172c|M.tuberculosis_H37Rv --AVPTTGVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQ
MMAR_4280|M.marinum_M --SAPTTGVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAA
MUL_1019|M.ulcerans_Agy99 --SAPTTGVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAA
Mflv_2738|M.gilvum_PYR-GCK --AAQALSVQPLS-----IASEMVSAASFTAG----STRILPVTDPRALA
Mvan_3794|M.vanbaalenii_PYR-1 -FAADGTPITPVSDDDVRAALELIGNLGSVAGPRKVTVRLGGHDHPEAAR
MAB_2679|M.abscessus_ATCC_1997 --DIRSASVRLSSLAFTPRAAEVPASPLAALKLSLSPASAAPASPLKRAP
TH_3064|M.thermoresistible__bu --DIAVTAEQPVLDASASREAVALLAAVQGLAVRPASPPVAP-----TAP
MSMEG_5127|M.smegmatis_MC2_155 --DVVVPAQPTAPQPELTQAMVDLLAA----------------------A
MAV_3172|M.avium_104 ERGVIYDIALWTVPFGLVGGRLYHLATDWRTYWGPGGAGFGAAVRIWDGG
Mb1205c|M.bovis_AF2122/97 ALRASADAYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNA
Rv1172c|M.tuberculosis_H37Rv ALRASADAYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNA
MMAR_4280|M.marinum_M ALNTSANSYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANA
MUL_1019|M.ulcerans_Agy99 ALNTSANSYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANA
Mflv_2738|M.gilvum_PYR-GCK ALTAFTQPWPGTPSDAADPTDLATVTTADEPLEDPVALNAASDVIDTVYA
Mvan_3794|M.vanbaalenii_PYR-1 AILPTARVVDAGGTDPAS-VDAPAAAADGQALDEPVAQNAASDLIDTVYS
MAB_2679|M.abscessus_ATCC_1997 LGQLATAVQPRAAAAPLPTPVSAPTQPDAATASSPVVASSLTNGIDQAYQ
TH_3064|M.thermoresistible__bu TPDEVQAAVTAIQELAAPGAPATTAAADSAIEVGTAAFPGAANAIKDVYN
MSMEG_5127|M.smegmatis_MC2_155 RRTTITIPVPPDAPRVAPPHGNAAPDAQATASGDVTVQNAASDFVVDAWE
MAV_3172|M.avium_104 LGIWGAVALGAVGAWIGCRRHGIPLPAFADALAPGIILAQAIGRLGNYFN
.
Mb1205c|M.bovis_AF2122/97 LSRVHSMFLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGAL
Rv1172c|M.tuberculosis_H37Rv LSRVQSMFLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGAL
MMAR_4280|M.marinum_M VSQVQSVFAGAG--SNALG--------ANASMLALAPTGGAATAAASGSL
MUL_1019|M.ulcerans_Agy99 VSQVQSVFAGAG--SNALG--------ANASMLALAPTGGAATAAASGSL
Mflv_2738|M.gilvum_PYR-GCK FTRYWANYVSLELGPWLINWVPFGY-LISDQILIWYPNFVLPVVDSFVYD
Mvan_3794|M.vanbaalenii_PYR-1 ISRYWANYVSLELGPWLINWIPFGY-LISDQIYIWYPDFVLPVVDSFVYD
MAB_2679|M.abscessus_ATCC_1997 FIQYWVDY-GVDLAQWGAGFVPVIGGLVSAQIGIVYDNLVRPIANSFVYN
TH_3064|M.thermoresistible__bu LIEPYVAW-GVEVAQWAVGWVPWVG-LLSGQIGIFY-TFGEAIVYSVVFN
MSMEG_5127|M.smegmatis_MC2_155 AAVPWIDY-GVGLVDGALGWVPGLA-IVGNQVSLLWTYLGYPVANSVVLD
MAV_3172|M.avium_104 QELYGRETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALVVQPTFLYE
:
Mb1205c|M.bovis_AF2122/97 LPRAGAAAA-------------------------AALPALAAES---IGN
Rv1172c|M.tuberculosis_H37Rv LPRAGAAAA-------------------------AALPALAAES---IGN
MMAR_4280|M.marinum_M LG-PIASAA-------------------------AAPAAILPVS---VAT
MUL_1019|M.ulcerans_Agy99 LG-PIASAA-------------------------AAPAAILPVS---VAT
Mflv_2738|M.gilvum_PYR-GCK FLDPVVNDP-------------------------LNLEVWAQGIGSIIDT
Mvan_3794|M.vanbaalenii_PYR-1 FLDPVVNDP-------------------------LNLNVWLDGIGDIINT
MAB_2679|M.abscessus_ATCC_1997 LVDPILNDPSFSNIVNSFGRFGSDIVNSVINFAWAEARYFLPPLPPLPGL
TH_3064|M.thermoresistible__bu VADWIGGTVGFG----------------------EGLANIAAATSQAVTD
MSMEG_5127|M.smegmatis_MC2_155 LVAPVVNAP-------------------------LNLDVWANGFGAVAST
MAV_3172|M.avium_104 LLWNLLIFVALL----------------------YADRRLTLGHGRLFAL
.
Mb1205c|M.bovis_AF2122/97 AIKNLYNA--------VEPWVQYG-FNLTAWAVGWLPYIGILAPQINFFY
Rv1172c|M.tuberculosis_H37Rv AIKNLYNA--------VEPWVQYG-FNLTAWAVGWLPYIGILAPQINFFY
MMAR_4280|M.marinum_M AIQNFYLA--------VEPWVQYG-FNLASWAVGWVPWIGILAPQINFFY
MUL_1019|M.ulcerans_Agy99 AIQNFCLA--------VEPWVQYG-FNLASWAVGWVPWIGILAPQINFFY
Mflv_2738|M.gilvum_PYR-GCK AVAGVRNG--------VTAEIQYI-LDFGWFPFPLPPLPSFPVPGAAGAS
Mvan_3794|M.vanbaalenii_PYR-1 ALTGVYNG--------VVGEIQYA-LSFDWFPIPLPPLPPFP-PLPIFDA
MAB_2679|M.abscessus_ATCC_1997 ALQTTTDANGAAPTSVHEALVPFT-KAFKDAEAHFAEALGLTKPDPKSAA
TH_3064|M.thermoresistible__bu LIRDEINWVRSFFPPLPPLPPVLP-AALPMSLPTSLPTSEAHPAQQVGIA
MSMEG_5127|M.smegmatis_MC2_155 TANSLVNTG------VAEFNYFFG-WLIPPVALTTPTETLAFDATVGADL
MAV_3172|M.avium_104 YVAGYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIGAVVYLMAAPKG
:
Mb1205c|M.bovis_AF2122/97 YLGEPIVQAVLFNAIDFVDG-------------TVTFSQALT--------
Rv1172c|M.tuberculosis_H37Rv YLGEPIVQAVLFNAIDFVDG-------------TVTFSQALT--------
MMAR_4280|M.marinum_M YLFEPIVQSGLFNTLDWLDG-------------TITFSQGLS--------
MUL_1019|M.ulcerans_Agy99 YLFEPIVQSGLFNTLDWLDG-------------TVTFSQGLSNF------
Mflv_2738|M.gilvum_PYR-GCK AESADADVQLAS--VDEADA-------------AGAVEDAVEGAEGGAAE
Mvan_3794|M.vanbaalenii_PYR-1 ADSAPTEVTLASSETDGDET-------------GATAIEATDSDDTDAVT
MAB_2679|M.abscessus_ATCC_1997 LEKTGTAAQTGESLKETTGESVQEEGKTAETGAATGTKEALDRKESAEGK
TH_3064|M.thermoresistible__bu KAGAAAEVAGSPTATTVVEG-------------DLPADEAPEPPAQAQRQ
MSMEG_5127|M.smegmatis_MC2_155 LKQARAAVTSLVEPAEGAEAAEAS--------EAPKAPESLESPEKPETK
MAV_3172|M.avium_104 REDPESLRGNQYVEEEPAEP------------EPATVAATTEAATEGVAA
Mb1205c|M.bovis_AF2122/97 ---------------------------------------NIETATAASIN
Rv1172c|M.tuberculosis_H37Rv ---------------------------------------NIETATAASIN
MMAR_4280|M.marinum_M ---------------------------------------NFWSATTASVN
MUL_1019|M.ulcerans_Agy99 ----------------------------------SQGLSNFWSATTASVN
Mflv_2738|M.gilvum_PYR-GCK A--VEVDG---DDIVAQKPADVSGEAVDEALVEEESVEEESVDVVDEESV
Mvan_3794|M.vanbaalenii_PYR-1 D--VPVDDPITETVVTPAPEDAAGEEAPAGTAAEDEPE-TPVEDVEESVE
MAB_2679|M.abscessus_ATCC_1997 A--SANDKATAVAEKTKAGDKATTESREPVTTATEAAKESTKDSVKDAAV
TH_3064|M.thermoresistible__bu P--VQRGALLAETDPVEDDSSAPDAGESPAPGVDVRPGPRPGTALRDSLQ
MSMEG_5127|M.smegmatis_MC2_155 TPDAPAAEFSAPAGTTENTASGVTENAENTEVVEDTTTPTKADTSTKAPV
MAV_3172|M.avium_104 PADGAEAAGADATAQRPEESAEPDVEKPESEETEAEAAEEPESEETEAAE
Mb1205c|M.bovis_AF2122/97 QFINTEINWIRGFLPPLPPISPPGFPSLP---------------------
Rv1172c|M.tuberculosis_H37Rv QFINTEINWIRGFLPPLPPISPPGFPSLP---------------------
MMAR_4280|M.marinum_M QFIQTEINWIRHFFPPFPPLP---F-------------------------
MUL_1019|M.ulcerans_Agy99 QFIQTEINWIRNFFPPFPPLP---F-------------------------
Mflv_2738|M.gilvum_PYR-GCK EAVDDETDQVEETVDEESAEDGATTDDEPTDED-------APA---GSDS
Mvan_3794|M.vanbaalenii_PYR-1 DAVEEDADEASGETGAETPAPAEDTGADGPGTD-------EPASEPASDE
MAB_2679|M.abscessus_ATCC_1997 PGVAADSDAASGNLTKGTLAAKETGNQQQSATDGKPSPSSAPADKPDKPV
TH_3064|M.thermoresistible__bu EVARAATASVEXXXX-GPPWPAGPAMPAPTGPPCSSPAGSAPPAPCAAFI
MSMEG_5127|M.smegmatis_MC2_155 KPVRTITKNIKRDLKKATAGLRGVVKDIRDGLVKPKKPATKPSKKAEPAK
MAV_3172|M.avium_104 EPGEPEAEEPEEPEAEEPEEPETEEPEADSDEEPEEESGEAPEQPVAEEP
.
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK GDDTSGSETE----------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 KDSVAASASGD---------------------------------------
MAB_2679|M.abscessus_ATCC_1997 KPKVPAASTTEHGSISAQGIVRGPVSQSTSGQSGPSASTPKTADSKVSSS
TH_3064|M.thermoresistible__bu TCSISELNIPVCPPSPPAP-------------------------------
MSMEG_5127|M.smegmatis_MC2_155 KAEPSKQSASESSSSDSDD-------------------------------
MAV_3172|M.avium_104 EPAPQQPETKRRWGARLRDRLSGR--------------------------
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 GASGFQTSDTGTPESKMSDTKTATGTTAGTKATETKPKAAETKPSDAKSS
TH_3064|M.thermoresistible__bu --------------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3172|M.avium_104 --------------------------------------------------
Mb1205c|M.bovis_AF2122/97 --------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 GSTTSGTKSPGTTAHDSANKPSASASSAAKSGGEGSKSSSGSHR
TH_3064|M.thermoresistible__bu --------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------
MAV_3172|M.avium_104 --------------------------------------------