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MNVSARAALAAGVTALTGGALMFTPSVLPATMSTVEVVRPVAFAADGTPITPVSDDDVRAALELIGNLGS VAGPRKVTVRLGGHDHPEAARAILPTARVVDAGGTDPASVDAPAAAADGQALDEPVAQNAASDLIDTVYS ISRYWANYVSLELGPWLINWIPFGYLISDQIYIWYPDFVLPVVDSFVYDFLDPVVNDPLNLNVWLDGIGD IINTALTGVYNGVVGEIQYALSFDWFPIPLPPLPPFPPLPIFDAADSAPTEVTLASSETDGDETGATAIE ATDSDDTDAVTDVPVDDPITETVVTPAPEDAAGEEAPAGTAAEDEPETPVEDVEESVEDAVEEDADEASG ETGAETPAPAEDTGADGPGTDEPASEPASDEKDSVAASASGD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3794 | - | - | 100% (392) | hypothetical protein Mvan_3794 |
| M. vanbaalenii PYR-1 | Mvan_5180 | - | 8e-10 | 29.13% (127) | hypothetical protein Mvan_5180 |
| M. vanbaalenii PYR-1 | Mvan_2723 | - | 1e-09 | 27.24% (257) | hypothetical protein Mvan_2723 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1205c | PE12 | 2e-06 | 23.29% (249) | PE family protein |
| M. gilvum PYR-GCK | Mflv_2738 | - | 2e-79 | 46.29% (404) | hypothetical protein Mflv_2738 |
| M. tuberculosis H37Rv | Rv1172c | PE12 | 2e-06 | 23.29% (249) | PE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2679 | - | 1e-23 | 26.41% (462) | hypothetical protein MAB_2679 |
| M. marinum M | MMAR_2416 | lgt | 1e-06 | 29.80% (151) | prolipoprotein diacylglyceryl transferases Lgt |
| M. avium 104 | MAV_0048 | - | 5e-05 | 31.43% (140) | hypothetical protein MAV_0048 |
| M. smegmatis MC2 155 | MSMEG_5127 | - | 7e-20 | 27.42% (361) | hypothetical protein MSMEG_5127 |
| M. thermoresistible (build 8) | TH_3064 | - | 3e-12 | 26.27% (354) | PUTATIVE putative PE family protein |
| M. ulcerans Agy99 | MUL_1019 | - | 2e-06 | 26.97% (152) | PE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1205c|M.bovis_AF2122/97 --------------------------------------MSFVFAAPEALA
Rv1172c|M.tuberculosis_H37Rv --------------------------------------MSFVFAAPEALA
MUL_1019|M.ulcerans_Agy99 --------------------------------------MSYVATVPEALT
Mvan_3794|M.vanbaalenii_PYR-1 ----------------------------------------MNVSARAALA
Mflv_2738|M.gilvum_PYR-GCK ------------------------------------MGNEMHASIRAALA
MAB_2679|M.abscessus_ATCC_1997 ----------------------------------------MDRTANPLFK
MSMEG_5127|M.smegmatis_MC2_155 ----------------------------------------MTVSVRAYLM
TH_3064|M.thermoresistible__bu --------------------------------------------------
MMAR_2416|M.marinum_M MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARG
MAV_0048|M.avium_104 ------------------------------------MAIFGRMTARQRLR
Mb1205c|M.bovis_AF2122/97 AAAADMAGIGSTLNAANVVA-------------AVPTTGVLAAAADEVST
Rv1172c|M.tuberculosis_H37Rv AAAADMAGIGSTLNAANVVA-------------AVPTTGVLAAAADEVST
MUL_1019|M.ulcerans_Agy99 AAASDAAGIGTTISSANAAA-------------SAPTTGVLAAAGDQVSA
Mvan_3794|M.vanbaalenii_PYR-1 AGVTALTGGALMFTPSVLPATMSTVEVVRPVAFAADGTPITPVSDDDVRA
Mflv_2738|M.gilvum_PYR-GCK AGVTTLTASALAFAPPPQPP-------------AAQALSVQPLS-----I
MAB_2679|M.abscessus_ATCC_1997 AGMAAITATALIVAPAVTPPTRQSIPLP-----DIRSASVRLSSLAFTPR
MSMEG_5127|M.smegmatis_MC2_155 AGAAAATATTIALTSVQVTP-------------PDVVVPAQPTAPQ----
TH_3064|M.thermoresistible__bu --VAAVGAAAVAFAPVQALPP------------DIAVTAEQPVLDASASR
MMAR_2416|M.marinum_M GERGVIYDIALWMVPFGLIGGRLYHLSTDWQTYFGEGGAGLGAALRIWDG
MAV_0048|M.avium_104 RATRESLSIPAFSSPVDCTPWVTGGLWP---AELSTVTPETATLAEYLKA
.
Mb1205c|M.bovis_AF2122/97 QVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRASADAYATAEASAAQT
Rv1172c|M.tuberculosis_H37Rv QVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRASADAYATAEASAAQT
MUL_1019|M.ulcerans_Agy99 QVAALFSS-HGEIYQRLSSQLST-FHDQFAAALNTSANSYASAEANAAKT
Mvan_3794|M.vanbaalenii_PYR-1 ALELIGNLGSVAGPRKVTVRLGGHDHPEAARAILPTARVVDAGGTDPAS-
Mflv_2738|M.gilvum_PYR-GCK ASEMVSAASFTAG----STRILPVTDPRALAALTAFTQPWPGTPSDAADP
MAB_2679|M.abscessus_ATCC_1997 AAEVPASPLAALKLSLSPASAAPASPLKRAPLGQLATAVQPRAAAAPLPT
MSMEG_5127|M.smegmatis_MC2_155 -----------------PELTQAMVDLLAAARRTTITIPVPPDAPRVAPP
TH_3064|M.thermoresistible__bu EAVALLAAVQG-----LAVRPASPPVAPTAPTPDEVQAAVTAIQELAAPG
MMAR_2416|M.marinum_M GLGIWGAVTLGTVGAWIGCRRRGIPLPAFLDAVAPGVVMGQAIGRLGNYF
MAV_0048|M.avium_104 DLQRIADGANDELRKLKRAGMTDTARQAAEARVIEQARTRAVRRVESTIR
Mb1205c|M.bovis_AF2122/97 MVNAVNAPARALLGHPLIS-ADASTGGGSNALSRV----HSMFLGTGG-S
Rv1172c|M.tuberculosis_H37Rv MVNAVNAPARALLGHPLIS-ADASTGGGSNALSRV----QSMFLGTGG-S
MUL_1019|M.ulcerans_Agy99 LLSAVNSPAEKLLGQPLMG-QGGIV---ANAVSQV----QSVFAGAG--S
Mvan_3794|M.vanbaalenii_PYR-1 VDAPAAAADGQALDEPVAQNAASDLIDTVYSISRY----WANYVSLELGP
Mflv_2738|M.gilvum_PYR-GCK TDLATVTTADEPLEDPVALNAASDVIDTVYAFTRY----WANYVSLELGP
MAB_2679|M.abscessus_ATCC_1997 PVSAPTQPDAATASSPVVASSLTNGIDQAYQFIQY----WVDYGVDLAQW
MSMEG_5127|M.smegmatis_MC2_155 HGNAAPDAQATASGDVTVQNAASDFVVDAWEAAVP----WIDYGVGLV-D
TH_3064|M.thermoresistible__bu APATTAAADSAIEVGTAAFPGAANAIKDVYNLIEP----YVAWGVEVA-Q
MMAR_2416|M.marinum_M NQELYGRETTVPWGLEIFYRRDPSGFVDVHSLDGV----STGQVAVVVQP
MAV_0048|M.avium_104 YLHAVQSGARPPAPPRPTLDAPGADLERTQVLPAVGDAEHTAGPPAQQTP
Mb1205c|M.bovis_AF2122/97 SALGGSAAANAAASGALQLQPTGGASGLSAVGALLPRAGAAAA-------
Rv1172c|M.tuberculosis_H37Rv SALGGSAAANAAASGALQLQPTGGASGLSAVGALLPRAGAAAA-------
MUL_1019|M.ulcerans_Agy99 NALG------ANAS-MLALAPTGGAATAAASGSLLG-PIASAA-------
Mvan_3794|M.vanbaalenii_PYR-1 WLINWIPFGYLISDQIYIWYPDFVLPVVDSFVYDFLDPVVNDP-------
Mflv_2738|M.gilvum_PYR-GCK WLINWVPFGYLISDQILIWYPNFVLPVVDSFVYDFLDPVVNDP-------
MAB_2679|M.abscessus_ATCC_1997 GAGFVPVIGGLVSAQIGIVYDNLVRPIANSFVYNLVDPILNDPSFSNIVN
MSMEG_5127|M.smegmatis_MC2_155 GALGWVPGLAIVGNQVSLLWTYLGYPVANSVVLDLVAPVVNAP-------
TH_3064|M.thermoresistible__bu WAVGWVPWVGLLSGQIGIFYT-FGEAIVYSVVFNVADWIGGTVG------
MMAR_2416|M.marinum_M TFLYELIWNLLVFAALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLRD
MAV_0048|M.avium_104 EARPRPTRRRAAEDEPAQLEETRVLPAIRDDAAAADASVPETPASETP--
Mb1205c|M.bovis_AF2122/97 ----------------------AALPALAAES---IGNAIKNLYNA----
Rv1172c|M.tuberculosis_H37Rv ----------------------AALPALAAES---IGNAIKNLYNA----
MUL_1019|M.ulcerans_Agy99 ----------------------AAPAAILPVS---VATAIQNFCLA----
Mvan_3794|M.vanbaalenii_PYR-1 ----------------------LNLNVWLDGIGDIINTALTGVYNG----
Mflv_2738|M.gilvum_PYR-GCK ----------------------LNLEVWAQGIGSIIDTAVAGVRNG----
MAB_2679|M.abscessus_ATCC_1997 SFGRFGS----DIVNSVINFAWAEARYFLPPLPPLPGLALQTTTDANGAA
MSMEG_5127|M.smegmatis_MC2_155 ----------------------LNLDVWANGFGAVASTTANSLVNTG---
TH_3064|M.thermoresistible__bu ------------------------FGEGLANIAAATSQAVTDLIRD----
MMAR_2416|M.marinum_M DTATHIAGIRINSFTSTFVFIGAVVYIILAPKGREDPASVRGTAAAAEEV
MAV_0048|M.avium_104 ----------------------VPEAPAAEAPVPEAPAPEAPAAEVPEAP
.
Mb1205c|M.bovis_AF2122/97 ----VEPWVQYGFN----------------LTAWAVGWLPYIGILAPQIN
Rv1172c|M.tuberculosis_H37Rv ----VEPWVQYGFN----------------LTAWAVGWLPYIGILAPQIN
MUL_1019|M.ulcerans_Agy99 ----VEPWVQYGFN----------------LASWAVGWVPWIGILAPQIN
Mvan_3794|M.vanbaalenii_PYR-1 ----VVGEIQYALS----------------FDWFPIPLPPLPPFP-PLPI
Mflv_2738|M.gilvum_PYR-GCK ----VTAEIQYILD----------------FGWFPFPLPPLPSFPVPGAA
MAB_2679|M.abscessus_ATCC_1997 PTSVHEALVPFTKA----------------FKDAEAHFAEALGLTKPDPK
MSMEG_5127|M.smegmatis_MC2_155 -----VAEFNYFFG----------------WLIPPVALTTPTETLAFDAT
TH_3064|M.thermoresistible__bu ---EINWVRSFFPP----------------LPPLPPVLPAALPMSLPTSL
MMAR_2416|M.marinum_M PEPEPAGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPETVGSAVAGDE
MAV_0048|M.avium_104 APEAPAAEVPEPLG--------EPTTRGRHHAPVPEPVAERVEPDIAAPA
Mb1205c|M.bovis_AF2122/97 F--FYYLGEPIVQAVLFNAIDFVDGTVT-------------FSQALTN--
Rv1172c|M.tuberculosis_H37Rv F--FYYLGEPIVQAVLFNAIDFVDGTVT-------------FSQALTN--
MUL_1019|M.ulcerans_Agy99 F--FYYLFEPIVQSGLFNTLDWLDGTVT-------------FSQGLSN--
Mvan_3794|M.vanbaalenii_PYR-1 F--DAADSAPTEVTLASSETDGDETGAT-------------AIEATDSDD
Mflv_2738|M.gilvum_PYR-GCK G--ASAESADADVQLAS--VDEADAAGA-------------VEDAVEGAE
MAB_2679|M.abscessus_ATCC_1997 S--AALEKTGTAAQTGESLKETTGESVQEEGKTAETGAATGTKEALDRKE
MSMEG_5127|M.smegmatis_MC2_155 VGADLLKQARAAVTSLVEPAEGAEAAEASEAP--------KAPESLESPE
TH_3064|M.thermoresistible__bu PTSEAHPAQQVGIAKAGAAAEVAGSPTATT----------VVEGDLPADE
MMAR_2416|M.marinum_M STADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAE
MAV_0048|M.avium_104 EAADLEQTQVIPVVRRDEPVPEPPVVAPPE----------PAEEPADSGR
Mb1205c|M.bovis_AF2122/97 --------------------------------------IET---------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------IET---------
MUL_1019|M.ulcerans_Agy99 --------------------------------------FSQGLS------
Mvan_3794|M.vanbaalenii_PYR-1 TDAVTDVPVDDPITETVVTPAPEDAA--GEEAPAGTAAEDEPE-------
Mflv_2738|M.gilvum_PYR-GCK GGAAEAVEVDG---DDIVAQKPADVS--GEAVDEALVEEESVEE------
MAB_2679|M.abscessus_ATCC_1997 SAEGKASANDKATAVAEKTKAGDKAT--TESREPVTTATEAAKE------
MSMEG_5127|M.smegmatis_MC2_155 KPETKTPDAPAAEFSAPAGTTENTASGVTENAENTEVVEDTTTP------
TH_3064|M.thermoresistible__bu APEPPAQAQRQPVQRGALLAETDPVEDDSSAPDAGESPAPGVDV------
MMAR_2416|M.marinum_M EAEPGEVEVAEAVEGEVEAAAEAEEAEEAEEAEEAEEAEEAEPGEIEVAE
MAV_0048|M.avium_104 HHAPADRDEPATEGRTAVADTDTAQPRVEKPAPTTVFDNNRLNR------
Mb1205c|M.bovis_AF2122/97 -------------ATAASINQFINTEINWIRGFLPP-------------L
Rv1172c|M.tuberculosis_H37Rv -------------ATAASINQFINTEINWIRGFLPP-------------L
MUL_1019|M.ulcerans_Agy99 ---------NFWSATTASVNQFIQTEINWIRNFFPP-------------F
Mvan_3794|M.vanbaalenii_PYR-1 ---------TPVEDVEESVEDAVEEDADEASGETGA-------------E
Mflv_2738|M.gilvum_PYR-GCK ---------ESVDVVDEESVEAVDDETDQVEETVDE-------------E
MAB_2679|M.abscessus_ATCC_1997 ---------STKDSVKDAAVPGVAADSDAASGNLTKGTLAAK------ET
MSMEG_5127|M.smegmatis_MC2_155 ---------TKADTSTKAPVKPVRTITKNIKRDLKKATAGLRGVVKDIRD
TH_3064|M.thermoresistible__bu ---------RPGPRPGTALRDSLQEVARAATASVEXX------------X
MMAR_2416|M.marinum_M AVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAAEAVEGEVEVA
MAV_0048|M.avium_104 -------LLEFVVRQEPRLNWAIGDRADGTTILVTDLAHGWIP-----SG
:
Mb1205c|M.bovis_AF2122/97 PPISPPGFPSLP--------------------------------------
Rv1172c|M.tuberculosis_H37Rv PPISPPGFPSLP--------------------------------------
MUL_1019|M.ulcerans_Agy99 PPLP---F------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 TPAPAEDTGADGPGTDEPASEPASDEKDSVAASASGD-------------
Mflv_2738|M.gilvum_PYR-GCK SAEDGATTDDEPTDEDAPA---GSDSGDDTSGSETE--------------
MAB_2679|M.abscessus_ATCC_1997 GNQQQSATDGKPSPSSAPADKPDKPVKPKVPAASTTEHGSISAQGIVRGP
MSMEG_5127|M.smegmatis_MC2_155 GLVKPKKPATKPSKKAEPAKKAEPSKQSASESSSSDSDD-----------
TH_3064|M.thermoresistible__bu XGPPWPAGPAMPAPTGPPCSSPAGSAPPAPCAAFITCSISELNIPVCPPS
MMAR_2416|M.marinum_M AEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGGQTGVDDAGEADA
MAV_0048|M.avium_104 IALPAGVRLLEPERRSGDVVALIGETVRRVTYTPGDTLRRSADFAATQSS
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 VSQSTSGQSGPSASTPKTADSKVSSSGASGFQTSDTGTPESKMSDTKTAT
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu PPAP----------------------------------------------
MMAR_2416|M.marinum_M EPDDDSTAAEPEVVVEQADIEEIEPQEPEAEAVAAAEATDADEGDGEPAE
MAV_0048|M.avium_104 SQPRELPPIDDLATAISRAIRGRAGLPKIVPRLADAAAAGAVIVDQEVDV
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 GTTAGTKATETKPKAAETKPSDAKSSGSTTSGTKSPGTTAHDSANKPSAS
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MMAR_2416|M.marinum_M PASDDLDAVAAEDADVDVDATATEAEESGDESPEPAADSEEPEADESAPE
MAV_0048|M.avium_104 LRVHLDTARYQLLVQYPNVNPALLLKCLLMATTEGIASGDPVSANYHLAW
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 ASSAAKSGGEGSKSSSGSHR------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MMAR_2416|M.marinum_M DSAEDTSSGESDTQSELEQSQTIEQGSDQTSAGDGEGPPPSAAVDGDTGP
MAV_0048|M.avium_104 YRTLAAPSPGG---------------------------------------
Mb1205c|M.bovis_AF2122/97 ------------------
Rv1172c|M.tuberculosis_H37Rv ------------------
MUL_1019|M.ulcerans_Agy99 ------------------
Mvan_3794|M.vanbaalenii_PYR-1 ------------------
Mflv_2738|M.gilvum_PYR-GCK ------------------
MAB_2679|M.abscessus_ATCC_1997 ------------------
MSMEG_5127|M.smegmatis_MC2_155 ------------------
TH_3064|M.thermoresistible__bu ------------------
MMAR_2416|M.marinum_M TRQGWRGRLRNRMRRSGR
MAV_0048|M.avium_104 ------------------