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MDRTANPLFKAGMAAITATALIVAPAVTPPTRQSIPLPDIRSASVRLSSLAFTPRAAEVPASPLAALKLS LSPASAAPASPLKRAPLGQLATAVQPRAAAAPLPTPVSAPTQPDAATASSPVVASSLTNGIDQAYQFIQY WVDYGVDLAQWGAGFVPVIGGLVSAQIGIVYDNLVRPIANSFVYNLVDPILNDPSFSNIVNSFGRFGSDI VNSVINFAWAEARYFLPPLPPLPGLALQTTTDANGAAPTSVHEALVPFTKAFKDAEAHFAEALGLTKPDP KSAALEKTGTAAQTGESLKETTGESVQEEGKTAETGAATGTKEALDRKESAEGKASANDKATAVAEKTKA GDKATTESREPVTTATEAAKESTKDSVKDAAVPGVAADSDAASGNLTKGTLAAKETGNQQQSATDGKPSP SSAPADKPDKPVKPKVPAASTTEHGSISAQGIVRGPVSQSTSGQSGPSASTPKTADSKVSSSGASGFQTS DTGTPESKMSDTKTATGTTAGTKATETKPKAAETKPSDAKSSGSTTSGTKSPGTTAHDSANKPSASASSA AKSGGEGSKSSSGSHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2679 | - | - | 100% (576) | hypothetical protein MAB_2679 |
| M. abscessus ATCC 19977 | MAB_0974 | - | 7e-13 | 26.89% (305) | hypothetical protein MAB_0974 |
| M. abscessus ATCC 19977 | MAB_0978 | - | 1e-11 | 25.68% (222) | hypothetical protein MAB_0978 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1205c | PE12 | 7e-14 | 31.10% (164) | PE family protein |
| M. gilvum PYR-GCK | Mflv_2738 | - | 8e-27 | 30.79% (354) | hypothetical protein Mflv_2738 |
| M. tuberculosis H37Rv | Rv1172c | PE12 | 8e-14 | 31.10% (164) | PE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4280 | - | 7e-16 | 35.19% (162) | PE family protein |
| M. avium 104 | MAV_0290 | - | 3e-07 | 24.72% (271) | hypothetical protein MAV_0290 |
| M. smegmatis MC2 155 | MSMEG_5127 | - | 1e-23 | 29.44% (394) | hypothetical protein MSMEG_5127 |
| M. thermoresistible (build 8) | TH_3064 | - | 1e-19 | 27.86% (384) | PUTATIVE putative PE family protein |
| M. ulcerans Agy99 | MUL_1019 | - | 3e-14 | 34.91% (169) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_3794 | - | 2e-23 | 27.61% (402) | hypothetical protein Mvan_3794 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MAV_0290|M.avium_104 MAQFGGLASPIPDPTPQPHGAASTTDIPVRGTPDAADTKPEPATESKPDA
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MAV_0290|M.avium_104 EEKRRPNRDGKTPADPKPVPDAGEKPDTDEKPKPDVDKAEPKAKVKDIGQ
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MAV_0290|M.avium_104 VTANDKVSTIGKSFGKAYLEAAKSPIKGIPAIVKAEYKAGTALGEKLAGK
Mb1205c|M.bovis_AF2122/97 ----MSFVFAAPEALAAAAADMAGIGSTLNAANVVA--------------
Rv1172c|M.tuberculosis_H37Rv ----MSFVFAAPEALAAAAADMAGIGSTLNAANVVA--------------
MMAR_4280|M.marinum_M ----MSYVAAVPEALTAAASDVAGIGTTISSANAAA--------------
MUL_1019|M.ulcerans_Agy99 ----MSYVATVPEALTAAASDAAGIGTTISSANAAA--------------
Mflv_2738|M.gilvum_PYR-GCK --MGNEMHASIRAALAAGVTTLTASALAFAPPPQPP--------------
Mvan_3794|M.vanbaalenii_PYR-1 ------MNVSARAALAAGVTALTGGALMFTPSVLPATMSTVEVVRPVA--
MAB_2679|M.abscessus_ATCC_1997 ------MDRTANPLFKAGMAAITATALIVAPAVTPPTRQSIPLP------
MSMEG_5127|M.smegmatis_MC2_155 ------MTVSVRAYLMAGAAAATATTIALTSVQVTP--------------
TH_3064|M.thermoresistible__bu ------------------VAAVGAAAVAFAPVQALPP-------------
MAV_0290|M.avium_104 IAGEGLLKSASRVSLKTAGRLVPGVGTAIGVISAYKNFEQGDYVGAAINM
. .
Mb1205c|M.bovis_AF2122/97 ---------------------------------------------AVPTT
Rv1172c|M.tuberculosis_H37Rv ---------------------------------------------AVPTT
MMAR_4280|M.marinum_M ---------------------------------------------SAPTT
MUL_1019|M.ulcerans_Agy99 ---------------------------------------------SAPTT
Mflv_2738|M.gilvum_PYR-GCK ---------------------------------------------AAQAL
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------FAADGT
MAB_2679|M.abscessus_ATCC_1997 ---------------------------------------------DIRSA
MSMEG_5127|M.smegmatis_MC2_155 ---------------------------------------------PDVVV
TH_3064|M.thermoresistible__bu ---------------------------------------------DIAVT
MAV_0290|M.avium_104 VSAIPGPIGWVGIAASTAWEAFDLGGNKIGQWDSPDGSTTHILPAAAHDI
Mb1205c|M.bovis_AF2122/97 GVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRASAD
Rv1172c|M.tuberculosis_H37Rv GVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRASAD
MMAR_4280|M.marinum_M GVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAAALNTSAN
MUL_1019|M.ulcerans_Agy99 GVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAAALNTSAN
Mflv_2738|M.gilvum_PYR-GCK SVQPLS-----IASEMVSAASFTAG----STRILPVTDPRALAALTAFTQ
Mvan_3794|M.vanbaalenii_PYR-1 PITPVSDDDVRAALELIGNLGSVAGPRKVTVRLGGHDHPEAARAILPTAR
MAB_2679|M.abscessus_ATCC_1997 SVRLSSLAFTPRAAEVPASPLAALKLSLSPASAAPASPLKRAPLGQLATA
MSMEG_5127|M.smegmatis_MC2_155 PAQPTAPQ---------------------PELTQAMVDLLAAARRTTITI
TH_3064|M.thermoresistible__bu AEQPVLDASASREAVALLAAVQG-----LAVRPASPPVAPTAPTPDEVQA
MAV_0290|M.avium_104 GGVTALDSQLREAQQCVFSFQDGPRGKVWDSNPPEALRLDGADIQKEIAE
Mb1205c|M.bovis_AF2122/97 AYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNALSRVHSM
Rv1172c|M.tuberculosis_H37Rv AYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNALSRVQSM
MMAR_4280|M.marinum_M SYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANAVSQVQSV
MUL_1019|M.ulcerans_Agy99 SYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANAVSQVQSV
Mflv_2738|M.gilvum_PYR-GCK PWPGTPSDAADPTDLATVTTADEPLEDPVALNAASDVIDTVYAFTRYWAN
Mvan_3794|M.vanbaalenii_PYR-1 VVDAGGTDPAS-VDAPAAAADGQALDEPVAQNAASDLIDTVYSISRYWAN
MAB_2679|M.abscessus_ATCC_1997 VQPRAAAAPLPTPVSAPTQPDAATASSPVVASSLTNGIDQAYQFIQYWVD
MSMEG_5127|M.smegmatis_MC2_155 PVPPDAPRVAPPHGNAAPDAQATASGDVTVQNAASDFVVDAWEAAVPWID
TH_3064|M.thermoresistible__bu AVTAIQELAAPGAPATTAAADSAIEVGTAAFPGAANAIKDVYNLIEPYVA
MAV_0290|M.avium_104 ALGGISDLFAEVDRVMSSAGEAYFDEYKARLQPHLEAMAALKEQVKPFTQ
Mb1205c|M.bovis_AF2122/97 FLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGALLPRAGAA
Rv1172c|M.tuberculosis_H37Rv FLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGALLPRAGAA
MMAR_4280|M.marinum_M FAGAG--SNALG--------ANASMLALAPTGGAATAAASGSLLG-PIAS
MUL_1019|M.ulcerans_Agy99 FAGAG--SNALG--------ANASMLALAPTGGAATAAASGSLLG-PIAS
Mflv_2738|M.gilvum_PYR-GCK YVSLELGPWLINWVPFGY-LISDQILIWYPNFVLPVVDSFVYDFLDPVVN
Mvan_3794|M.vanbaalenii_PYR-1 YVSLELGPWLINWIPFGY-LISDQIYIWYPDFVLPVVDSFVYDFLDPVVN
MAB_2679|M.abscessus_ATCC_1997 Y-GVDLAQWGAGFVPVIGGLVSAQIGIVYDNLVRPIANSFVYNLVDPILN
MSMEG_5127|M.smegmatis_MC2_155 Y-GVGLVDGALGWVPGLA-IVGNQVSLLWTYLGYPVANSVVLDLVAPVVN
TH_3064|M.thermoresistible__bu W-GVEVAQWAVGWVPWVG-LLSGQIGIFYT-FGEAIVYSVVFNVADWIGG
MAV_0290|M.avium_104 QLGNASDGAATAYTAVLDANRAAREQLVADGKLSDQGPASTFTSAVSAAG
. :
Mb1205c|M.bovis_AF2122/97 AA-------------------------AALPALAAES---IGNAIKNLYN
Rv1172c|M.tuberculosis_H37Rv AA-------------------------AALPALAAES---IGNAIKNLYN
MMAR_4280|M.marinum_M AA-------------------------AAPAAILPVS---VATAIQNFYL
MUL_1019|M.ulcerans_Agy99 AA-------------------------AAPAAILPVS---VATAIQNFCL
Mflv_2738|M.gilvum_PYR-GCK DP-------------------------LNLEVWAQGIGSIIDTAVAGVRN
Mvan_3794|M.vanbaalenii_PYR-1 DP-------------------------LNLNVWLDGIGDIINTALTGVYN
MAB_2679|M.abscessus_ATCC_1997 DPSFSNIVNSFGRFGSDIVNSVINFAWAEARYFLPPLPPLPGLALQTTTD
MSMEG_5127|M.smegmatis_MC2_155 AP-------------------------LNLDVWANGFGAVASTTANSLVN
TH_3064|M.thermoresistible__bu TVG--------------------------FGEGLANIAAATSQAVTDLIR
MAV_0290|M.avium_104 SQVTAADQNIANLFG------------EPAAVLTATVASGTGTRIDPSKK
Mb1205c|M.bovis_AF2122/97 A--------VEPWVQYGFNLTAWAVGWLPYIGILAPQINF--FYYLGEPI
Rv1172c|M.tuberculosis_H37Rv A--------VEPWVQYGFNLTAWAVGWLPYIGILAPQINF--FYYLGEPI
MMAR_4280|M.marinum_M A--------VEPWVQYGFNLASWAVGWVPWIGILAPQINF--FYYLFEPI
MUL_1019|M.ulcerans_Agy99 A--------VEPWVQYGFNLASWAVGWVPWIGILAPQINF--FYYLFEPI
Mflv_2738|M.gilvum_PYR-GCK G--------VTAEIQYILDFGWFPFPLPPLPSFPVPGAAG--ASAESADA
Mvan_3794|M.vanbaalenii_PYR-1 G--------VVGEIQYALSFDWFPIPLPPLPPFP-PLPIF--DAADSAPT
MAB_2679|M.abscessus_ATCC_1997 ANGAAPTSVHEALVPFTKAFKDAEAHFAEALGLTKPDPKS--AALEKTGT
MSMEG_5127|M.smegmatis_MC2_155 TG--------VAEFNYFFGWLIPPVALTTPTETLAFDATVGADLLKQARA
TH_3064|M.thermoresistible__bu D-------EINWVRSFFPPLPPLPPVLPAALPMSLPTSLPTSEAHPAQQV
MAV_0290|M.avium_104 GAPVQTTASPAAQTPVTPTSQTPTVTPKTETPAKTTDALGDLLRSLNQKQ
Mb1205c|M.bovis_AF2122/97 VQAVLFNAIDFVDG--------------TVTFSQALT-------------
Rv1172c|M.tuberculosis_H37Rv VQAVLFNAIDFVDG--------------TVTFSQALT-------------
MMAR_4280|M.marinum_M VQSGLFNTLDWLDG--------------TITFSQGLS-------------
MUL_1019|M.ulcerans_Agy99 VQSGLFNTLDWLDG--------------TVTFSQGLSNF-----------
Mflv_2738|M.gilvum_PYR-GCK DVQLAS--VDEADA--------------AGAVEDAVEGAEGGAAEAVEVD
Mvan_3794|M.vanbaalenii_PYR-1 EVTLASSETDGDET--------------GATAIEATDSDDTDAVTDVPVD
MAB_2679|M.abscessus_ATCC_1997 AAQTGESLKETTGESVQEEGK-TAETGAATGTKEALDRKESAEGKASAND
MSMEG_5127|M.smegmatis_MC2_155 AVTSLVEPAEGAEAAEAS---------EAPKAPESLESPEKPETKTPDAP
TH_3064|M.thermoresistible__bu GIAKAGAAAEVAGSP-----------TATTVVEGDLPADEAPEPPAQAQR
MAV_0290|M.avium_104 QMPTTPSTPNLGNGLGSGSPLGTGGSPLSTSPSKPLDTSSDRKLDDGRKG
:
Mb1205c|M.bovis_AF2122/97 -----NIETATAASIN-----------------------------QFINT
Rv1172c|M.tuberculosis_H37Rv -----NIETATAASIN-----------------------------QFINT
MMAR_4280|M.marinum_M -----NFWSATTASVN-----------------------------QFIQT
MUL_1019|M.ulcerans_Agy99 SQGLSNFWSATTASVN-----------------------------QFIQT
Mflv_2738|M.gilvum_PYR-GCK G---DDIVAQKPADVSGEAV--DEALVEEESVEEESVDVVDEESVEAVDD
Mvan_3794|M.vanbaalenii_PYR-1 DPITETVVTPAPEDAAGEEA--PAGTAAEDEPE-TPVEDVEESVEDAVEE
MAB_2679|M.abscessus_ATCC_1997 KATAVAEKTKAGDKATTESR--EPVTTATEAAKESTKDSVKDAAVPGVAA
MSMEG_5127|M.smegmatis_MC2_155 AAEFSAPAGTTENTASGVTENAENTEVVEDTTTPTKADTSTKAPVKPVRT
TH_3064|M.thermoresistible__bu QPVQRGALLAETDPVEDDSSAPDAGESPAPGVDVRPGPRPGTALRDSLQE
MAV_0290|M.avium_104 EEKKEERKLAEPKKEKSETKPSLAASKTDNAKAPESKLATAEKPGAHTAA
Mb1205c|M.bovis_AF2122/97 EINWIRGFLPPLPPISPPGFPSLP--------------------------
Rv1172c|M.tuberculosis_H37Rv EINWIRGFLPPLPPISPPGFPSLP--------------------------
MMAR_4280|M.marinum_M EINWIRHFFPPFPPLP---F------------------------------
MUL_1019|M.ulcerans_Agy99 EINWIRNFFPPFPPLP---F------------------------------
Mflv_2738|M.gilvum_PYR-GCK ETDQVEETVDEESAEDGATTDDEPTDED-------APA---GSDSGDDTS
Mvan_3794|M.vanbaalenii_PYR-1 DADEASGETGAETPAPAEDTGADGPGTD-------EPASEPASDEKDSVA
MAB_2679|M.abscessus_ATCC_1997 DSDAASGNLTKGTLAAKETGNQQQSATDGKPSPSSAPADKPDKPVKPKVP
MSMEG_5127|M.smegmatis_MC2_155 ITKNIKRDLKKATAGLRGVVKDIRDGLVKPKKPATKPSKKAEPAKKAEPS
TH_3064|M.thermoresistible__bu VARAATASVEXXXXGPPWPAGPAMPAPTGPPCSSPAGSAPPAPCAAFITC
MAV_0290|M.avium_104 VPAQPSAAAAAANPAAPAAQGQSAPPEQSKQVDVKGTRVEFPDAKTAKLA
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK GSETE---------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 ASASGD--------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 AASTTEHGSISAQGIVRGPVSQSTSGQSGPSASTPKTADSKVSSSGASGF
MSMEG_5127|M.smegmatis_MC2_155 KQSASESSSSDSDD------------------------------------
TH_3064|M.thermoresistible__bu SISELNIPVCPPSPPAP---------------------------------
MAV_0290|M.avium_104 SLLANADPAHPLSLAEAAKMAGLTPPVPGQDPGSQVAPAQAKPGDLLVAG
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 QTSDTGTPESKMSDTKTATGTTAGTKATETKPKAAETKPSDAKSSGSTTS
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MAV_0290|M.avium_104 DKKYMLLEPGKFYDLQEYKVVSADQLPQDAGSRGGYFHLNDPSPTGAPGT
Mb1205c|M.bovis_AF2122/97 --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4280|M.marinum_M --------------------------------------------------
MUL_1019|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 GTKSPGTTAHDSANKPSASASSAAKSGGEGSKSSSGSHR-----------
MSMEG_5127|M.smegmatis_MC2_155 --------------------------------------------------
TH_3064|M.thermoresistible__bu --------------------------------------------------
MAV_0290|M.avium_104 QPVSGQTPGGVDQAVPGGTPPPAAPADATPQKPHDPAAGAPAPSGGVPSA
Mb1205c|M.bovis_AF2122/97 -------------------------------------------
Rv1172c|M.tuberculosis_H37Rv -------------------------------------------
MMAR_4280|M.marinum_M -------------------------------------------
MUL_1019|M.ulcerans_Agy99 -------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK -------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1 -------------------------------------------
MAB_2679|M.abscessus_ATCC_1997 -------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155 -------------------------------------------
TH_3064|M.thermoresistible__bu -------------------------------------------
MAV_0290|M.avium_104 GTPGAPKPTATGGGPSSAEATQTGVGQPSPSPSTSALDPTAVR